ID

44964

Descrição

Principal Investigator: S. Faraone, SUNY Upstate Medical University, Syracuse, NY, USA MeSH: Attention Deficit Disorder with Hyperactivity https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs000016 The goal of the project is to complete a 600,000 tag SNP genome-wide association scan of 958 parent-child trios from the International Multisite ADHD Genetics (IMAGE) project, in order to assess the association of SNP markers with ADHD, analyze quantitative ADHD phenotypes, complete copy number analyses, assess parent of origin effects and season of birth effects, and test for epistasis among apparently uncorrelated genes. *Acquiring DNA Samples* All consent forms stipulate that the samples can only be used by researchers who have been approved by the National Institute of Mental Health (NIMH), National Institutes of Health. All consent forms, except those used at the Zürich site (N=141 subjects), explicitly indicate that the samples may be used by researchers from commercial enterprises seeking to benefit financially from the analysis of the samples. The Zürich consent does not prohibit such use. The Zürich consent form also included an "opt out" that allowed the subjects to indicate that they did not want their samples stored at the NIMH repository or used by researchers external to the project. No subjects enrolled in the project opted out. *Consent groups and participant set* - ADHD (ADHD): 2758 (924 trios)

Link

https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs000016

Palavras-chave

  1. 11/05/2022 11/05/2022 - Martin Dugas
  2. 11/05/2022 11/05/2022 - Martin Dugas
  3. 12/05/2022 12/05/2022 - Martin Dugas
  4. 20/05/2022 20/05/2022 - Dr. Christian Niklas
Titular dos direitos

S. Faraone, SUNY Upstate Medical University, Syracuse, NY, USA

Transferido a

20 de maio de 2022

DOI

Para um pedido faça login.

Licença

Creative Commons BY-NC 4.0

Comentários do modelo :

Aqui pode comentar o modelo. Pode comentá-lo especificamente através dos balões de texto nos grupos de itens e itens.

Comentários do grupo de itens para :

Comentários do item para :


Sem comentários

Para descarregar formulários, precisa de ter uma sessão iniciada. Por favor faça login ou registe-se gratuitamente.

dbGaP phs000016 International Multi-Center ADHD Genetics Project

Eligibility Criteria

  1. StudyEvent: SEV1
    1. Eligibility Criteria
    2. The data table contains the main diagnosis (DSM-IV), information on comorbidity, prorated hyperactivity scores (quantitative trait 1, 2, 3, 4), I.Q. score, medication status (n=10 variables) and sociodemographic information (n=12 variables).
    3. The data table contains information obtained through the Conners' behavioral rating scale (n=80 questions), describing the child's behavior as observed by the parent.
    4. The data table contains information obtained through the Conners' behavioral rating scale (n=59 questions), describing the child's behavior as observed by a teacher.
    5. The data table contains information obtained through the PACS (Parental Account of Childhood Symptoms) interview administered by a trained interviewer (n=200 questions). Questions represent four behavioral sub-categories: emotional pattern; activity level and inattentive behavior; disruptive behavior; comorbidity and other problems (including autism spectrum disorders).
    6. The data table contains information obtained through the SDQ (Strength and Difficulties, n=25 questions) questionnaire describing the child's behavior as observed by the parent. The questions address five subcategories: emotional symptoms scale; conduct problem scale; hyperactivity scale; peer problems scale; prosocial scale.
    7. The data table contains information obtained through the SDQ (Strength and Difficulties, n=25 questions) questionnaire describing the child's behavior as observed by a teacher. The questions address five subcategories: emotional symptoms scale; conduct problem scale; hyperactivity scale; peer problems scale; prosocial scale.
    8. ADHD Pedigree Information
    9. Subject - Consent Information
    10. Subject - Sample Mapping
Inclusion and exclusion criteria
Descrição

Inclusion and exclusion criteria

Proband diagnosis: combined subtype ADHD
Descrição

Elig.phs000016.v2.p2.1

Tipo de dados

boolean

Children aged 6-17 years (inclusive)
Descrição

Elig.phs000016.v2.p2.2

Tipo de dados

boolean

One or more sibling(s) in the same age range
Descrição

Elig.phs000016.v2.p2.3

Tipo de dados

boolean

Both parents available to provide DNA sample or one parent available plus two or more siblings
Descrição

Elig.phs000016.v2.p2.4

Tipo de dados

boolean

IQ above 70
Descrição

Elig.phs000016.v2.p2.5

Tipo de dados

boolean

Free of single-gene disorders known to be associated with ADHD (e.g. fragile-X, phenylketonuria, hypercalcaemia, thyroid hormone resistance)
Descrição

Elig.phs000016.v2.p2.6

Tipo de dados

boolean

Free of neurological disease and damage (e.g. hemiplegia and other cerebral palsies, epilepsy, hydrocephalus, post- encephalitic syndromes, psychosis, sensorimotor handicaps)
Descrição

Elig.phs000016.v2.p2.7

Tipo de dados

boolean

Living at home with at least one biological parent and one full sibling
Descrição

Elig.phs000016.v2.p2.8

Tipo de dados

boolean

Not meeting criteria for autism or Asperger's syndrome
Descrição

Elig.phs000016.v2.p2.9

Tipo de dados

boolean

Similar models

Eligibility Criteria

  1. StudyEvent: SEV1
    1. Eligibility Criteria
    2. The data table contains the main diagnosis (DSM-IV), information on comorbidity, prorated hyperactivity scores (quantitative trait 1, 2, 3, 4), I.Q. score, medication status (n=10 variables) and sociodemographic information (n=12 variables).
    3. The data table contains information obtained through the Conners' behavioral rating scale (n=80 questions), describing the child's behavior as observed by the parent.
    4. The data table contains information obtained through the Conners' behavioral rating scale (n=59 questions), describing the child's behavior as observed by a teacher.
    5. The data table contains information obtained through the PACS (Parental Account of Childhood Symptoms) interview administered by a trained interviewer (n=200 questions). Questions represent four behavioral sub-categories: emotional pattern; activity level and inattentive behavior; disruptive behavior; comorbidity and other problems (including autism spectrum disorders).
    6. The data table contains information obtained through the SDQ (Strength and Difficulties, n=25 questions) questionnaire describing the child's behavior as observed by the parent. The questions address five subcategories: emotional symptoms scale; conduct problem scale; hyperactivity scale; peer problems scale; prosocial scale.
    7. The data table contains information obtained through the SDQ (Strength and Difficulties, n=25 questions) questionnaire describing the child's behavior as observed by a teacher. The questions address five subcategories: emotional symptoms scale; conduct problem scale; hyperactivity scale; peer problems scale; prosocial scale.
    8. ADHD Pedigree Information
    9. Subject - Consent Information
    10. Subject - Sample Mapping
Name
Tipo
Description | Question | Decode (Coded Value)
Tipo de dados
Alias
Item Group
Inclusion and exclusion criteria
Elig.phs000016.v2.p2.1
Item
Proband diagnosis: combined subtype ADHD
boolean
Elig.phs000016.v2.p2.2
Item
Children aged 6-17 years (inclusive)
boolean
Elig.phs000016.v2.p2.3
Item
One or more sibling(s) in the same age range
boolean
Elig.phs000016.v2.p2.4
Item
Both parents available to provide DNA sample or one parent available plus two or more siblings
boolean
Elig.phs000016.v2.p2.5
Item
IQ above 70
boolean
Elig.phs000016.v2.p2.6
Item
Free of single-gene disorders known to be associated with ADHD (e.g. fragile-X, phenylketonuria, hypercalcaemia, thyroid hormone resistance)
boolean
Elig.phs000016.v2.p2.7
Item
Free of neurological disease and damage (e.g. hemiplegia and other cerebral palsies, epilepsy, hydrocephalus, post- encephalitic syndromes, psychosis, sensorimotor handicaps)
boolean
Elig.phs000016.v2.p2.8
Item
Living at home with at least one biological parent and one full sibling
boolean
Elig.phs000016.v2.p2.9
Item
Not meeting criteria for autism or Asperger's syndrome
boolean

Use este formulário para feedback, perguntas e sugestões de aperfeiçoamento.

Campos marcados com * são obrigatórios.

Do you need help on how to use the search function? Please watch the corresponding tutorial video for more details and learn how to use the search function most efficiently.

Watch Tutorial