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ID
44936
Description
https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs000016.v2.p2 The goal of the project is to complete a 600,000 tag SNP genome-wide association scan of 958 parent-child trios from the International Multisite ADHD Genetics (IMAGE) project, in order to assess the association of SNP markers with ADHD, analyze quantitative ADHD phenotypes, complete copy number analyses, assess parent of origin effects and season of birth effects, and test for epistasis among apparently uncorrelated genes. *Acquiring DNA Samples* All consent forms stipulate that the samples can only be used by researchers who have been approved by the National Institute of Mental Health (NIMH), National Institutes of Health. All consent forms, except those used at the Zürich site (N=141 subjects), explicitly indicate that the samples may be used by researchers from commercial enterprises seeking to benefit financially from the analysis of the samples. The Zürich consent does not prohibit such use. The Zürich consent form also included an "opt out" that allowed the subjects to indicate that they did not want their samples stored at the NIMH repository or used by researchers external to the project. No subjects enrolled in the project opted out. *Consent groups and participant set* - ADHD (ADHD): 2758 (924 trios)
Link
https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs000016.v2.p2
Keywords
Versions (4)
- 5/11/22 5/11/22 - Martin Dugas
- 5/11/22 5/11/22 - Martin Dugas
- 5/12/22 5/12/22 - Martin Dugas
- 5/20/22 5/20/22 - Dr. Christian Niklas
Copyright Holder
S. Faraone, SUNY Upstate Medical University, Syracuse, NY, USA
Uploaded on
May 11, 2022
DOI
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License
Creative Commons BY 4.0
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phs000016.v2.p2 International Multi-Center ADHD Genetics Project
The data table contains the main diagnosis (DSM-IV), information on comorbidity, prorated hyperactivity scores (quantitative trait 1, 2, 3, 4), I.Q. score, medication status (n=10 variables) and sociodemographic information (n=12 variables).
- StudyEvent: SEV1
- The data table contains the main diagnosis (DSM-IV), information on comorbidity, prorated hyperactivity scores (quantitative trait 1, 2, 3, 4), I.Q. score, medication status (n=10 variables) and sociodemographic information (n=12 variables).
- The data table contains information obtained through the Conners' behavioral rating scale (n=80 questions), describing the child's behavior as observed by the parent.
- The data table contains information obtained through the Conners' behavioral rating scale (n=59 questions), describing the child's behavior as observed by a teacher.
- The data table contains information obtained through the PACS (Parental Account of Childhood Symptoms) interview administered by a trained interviewer (n=200 questions). Questions represent four behavioral sub-categories: emotional pattern; activity level and inattentive behavior; disruptive behavior; comorbidity and other problems (including autism spectrum disorders).
- The data table contains information obtained through the SDQ (Strength and Difficulties, n=25 questions) questionnaire describing the child's behavior as observed by the parent. The questions address five subcategories: emotional symptoms scale; conduct problem scale; hyperactivity scale; peer problems scale; prosocial scale.
- The data table contains information obtained through the SDQ (Strength and Difficulties, n=25 questions) questionnaire describing the child's behavior as observed by a teacher. The questions address five subcategories: emotional symptoms scale; conduct problem scale; hyperactivity scale; peer problems scale; prosocial scale.
- ADHD Pedigree Information
- Subject - Consent Information
- Subject - Sample Mapping
Similar models
The data table contains the main diagnosis (DSM-IV), information on comorbidity, prorated hyperactivity scores (quantitative trait 1, 2, 3, 4), I.Q. score, medication status (n=10 variables) and sociodemographic information (n=12 variables).
- StudyEvent: SEV1
- The data table contains the main diagnosis (DSM-IV), information on comorbidity, prorated hyperactivity scores (quantitative trait 1, 2, 3, 4), I.Q. score, medication status (n=10 variables) and sociodemographic information (n=12 variables).
- The data table contains information obtained through the Conners' behavioral rating scale (n=80 questions), describing the child's behavior as observed by the parent.
- The data table contains information obtained through the Conners' behavioral rating scale (n=59 questions), describing the child's behavior as observed by a teacher.
- The data table contains information obtained through the PACS (Parental Account of Childhood Symptoms) interview administered by a trained interviewer (n=200 questions). Questions represent four behavioral sub-categories: emotional pattern; activity level and inattentive behavior; disruptive behavior; comorbidity and other problems (including autism spectrum disorders).
- The data table contains information obtained through the SDQ (Strength and Difficulties, n=25 questions) questionnaire describing the child's behavior as observed by the parent. The questions address five subcategories: emotional symptoms scale; conduct problem scale; hyperactivity scale; peer problems scale; prosocial scale.
- The data table contains information obtained through the SDQ (Strength and Difficulties, n=25 questions) questionnaire describing the child's behavior as observed by a teacher. The questions address five subcategories: emotional symptoms scale; conduct problem scale; hyperactivity scale; peer problems scale; prosocial scale.
- ADHD Pedigree Information
- Subject - Consent Information
- Subject - Sample Mapping
Name
Type
Description | Question | Decode (Coded Value)
Data type
Alias
subid
Item
Child's Project ID
text
father
Item
Father's Project ID
text
mother
Item
Mother's Project ID
text
CL Item
Male (1)
CL Item
Female (2)
age
Item
Age at assessment
text
Item
Main Diagnosis: DSM-IV (Diagnostic and Statistical Manual [of mental disease], IVth edition) ADHD Diagnosis
text
Code List
Main Diagnosis: DSM-IV (Diagnostic and Statistical Manual [of mental disease], IVth edition) ADHD Diagnosis
CL Item
Non-ADHD (0)
CL Item
Inattentive subtype (1)
CL Item
Hyperactive subtype (2)
CL Item
Combined subtype (3)
CL Item
ADHD-NOS (Attention Deficit Hyperactivity Disorder-Not Otherwise Specified) (4)
CL Item
Not available (NA)
dna
Item
DNA barcode at local database/ also sent to Perlegen
text
sdqp
Item
Quantitative trait 1; prorated SDQ Hyperactivity T score, parent's version
text
sdqt
Item
Quantitative trait 2; prorated SDQ Hyperactivity T score, teacher's version
text
conp
Item
Quantitative trait 3; prorated Conners' Hyperactivity T score, parents' version
text
cont
Item
Quantitative trait 4; prorated Conners' Hyperactivity T score, teachers' version
text
CL Item
No (0)
CL Item
Yes/probable (1)
CL Item
Not enough information to make the diagnosis (9)
CL Item
Not Applicable (NA)
CL Item
No (0)
CL Item
Yes/probable (1)
CL Item
Not enough information to make the diagnosis (9)
CL Item
Not Applicable (NA)
CL Item
Currently not taking medication: rate behaviour over last 6 months with special reference to a representative period (1)
CL Item
Off medication for 1-week: rate behaviour during time off medication (2)
CL Item
Intermittent use of medication: rate behaviour for days off medication (3)
CL Item
Constant use of medication: rate behaviour for last period off medication (retrospective assessment) (4)
CL Item
Constant use of medication, no period off in last 2-years: rating is for behaviour while medicated (5)
CL Item
Not Applicable (NA)
dges
Item
Subject's gestational age at birth in weeks
text
iq
Item
Full scale I.Q. (prorated)
text
CL Item
Not answered (0)
CL Item
European origin (predominantly white Caucasian) (1)
CL Item
Asian origin (2)
CL Item
African origin (3)
CL Item
Mixed ethnicity (4)
CL Item
Other (5)
CL Item
Don't know (6)
CL Item
Not Applicable (NA)
CL Item
Not answered (0)
CL Item
European origin (predominantly white Caucasian) (1)
CL Item
Asian origin (2)
CL Item
African origin (3)
CL Item
Mixed ethnicity (4)
CL Item
Other (5)
CL Item
Don't know (6)
CL Item
Not Applicable (NA)
CL Item
Not answered (0)
CL Item
European origin (predominantly white Caucasian) (1)
CL Item
Asian origin (2)
CL Item
African origin (3)
CL Item
Mixed ethnicity (4)
CL Item
Other (5)
CL Item
Don't know (6)
CL Item
Not Applicable (NA)
CL Item
Not answered (0)
CL Item
European origin (predominantly white Caucasian) (1)
CL Item
Asian origin (2)
CL Item
African origin (3)
CL Item
Mixed ethnicity (4)
CL Item
Other (5)
CL Item
Don't know (6)
CL Item
Not Applicable (NA)
CL Item
Not answered (0)
CL Item
European origin (predominantly white Caucasian) (1)
CL Item
Asian origin (2)
CL Item
African origin (3)
CL Item
Mixed ethnicity (4)
CL Item
Other (5)
CL Item
Don't know (6)
CL Item
Not Applicable (NA)
CL Item
Not answered (0)
CL Item
European origin (predominantly white Caucasian) (1)
CL Item
Asian origin (2)
CL Item
African origin (3)
CL Item
Mixed ethnicity (4)
CL Item
Other (5)
CL Item
Don't know (6)
CL Item
Not Applicable (NA)
CL Item
Not answered (0)
CL Item
European origin (predominantly white Caucasian) (1)
CL Item
Asian origin (2)
CL Item
African origin (3)
CL Item
Mixed ethnicity (4)
CL Item
Other (5)
CL Item
Don't know (6)
CL Item
Not Applicable (NA)
CL Item
Not completed (0)
CL Item
Professional (1)
CL Item
Clerk (2)
CL Item
Services/Sales (3)
CL Item
Labourer (4)
CL Item
Other (5)
CL Item
Not Applicable (NA)
CL Item
Not completed (0)
CL Item
Professional (1)
CL Item
Clerk (2)
CL Item
Services/Sales (3)
CL Item
Labourer (4)
CL Item
Other (5)
CL Item
Not Applicable (NA)
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