ID

16936

Beschrijving

NINDS Common Data Elements, Multiple Sclerosis Laboratory Tests Recommendations Table 3 – CSF and Table 4 – CSF Culture Used from the National Institute of Neurological Disorders and Stroke Common Data Elements (https://www.commondataelements.ninds.nih.gov/) References: Grinnon ST, Miller K, Marler JR, Lu Y, Stout A, Odenkirchen J, Kunitz S. National Institute of Neurological Disorders and Stroke Common Data Element Project - approach and methods. Clin Trials. 2012;9(3):322-9.

Link

https://www.commondataelements.ninds.nih.gov/

Trefwoorden

Versies (1)
  1. 15-08-16 15-08-16 -
Geüploaded op

15 augustus 2016

DOI

Voor een aanvraag inloggen.

Licentie

Creative Commons BY-NC 3.0
Model Commentaren :

Hier kunt u commentaar leveren op het model. U kunt de tekstballonnen bij de itemgroepen en items gebruiken om er specifiek commentaar op te geven.

Terug naar het model Commentaren
Itemgroep Commentaren voor :

Item Commentaren voor :

U moet ingelogd zijn om formulieren te downloaden. AUB inloggen of schrijf u gratis in.

NINDS CDE Laboratory Tests Recommendations Table 3 – CSF and Table 4 – CSF Culture Multiple Sclerosis

Engels

Laboratory Tests Recommendations Table 3 – CSF and Table 4 – CSF Culture

1 Formulieren  
Table 3 – CSF
Beschrijving

Table 3 – CSF

Alias
UMLS CUI-1
C0007806
Albumin index
Beschrijving

CSF to serum albumin ratio, x100. Reflects BBB permeability.

Datatype

float

Maateenheden
  • mg/dL
Alias
UMLS CUI [1]
C0201838
mg/dL
Albumin, CSF
Beschrijving

Major CSF protein component. Originates from blood.

Datatype

float

Maateenheden
  • mg/dL
Alias
UMLS CUI [1,1]
C0201838
UMLS CUI [1,2]
C0007806
mg/dL
Cell count and Diff, CSF
Beschrijving

WBC components. Predominantly mononuclears (lymphocytes, monocytes) but can also include neutrophils, eosinophils, plasma cells and other cells.

Datatype

float

Maateenheden
  • cells/µL
Alias
UMLS CUI [1]
C0007584
cells/µL
CSF lactate
Beschrijving

CSF lactic acid level. Increased with tissue acidosis, anaerobic metabolism.

Datatype

float

Maateenheden
  • mmol/L
Alias
UMLS CUI [1,1]
C0202113
UMLS CUI [1,2]
C0007806
mmol/L
CSF PCR for viruses
Beschrijving

Virus nucleic acid (DNA or RNA) detection in CSF.

Datatype

text

Alias
UMLS CUI [1,1]
C0032520
UMLS CUI [1,2]
C0042776
UMLS CUI [1,3]
C0007806
Cytopathology, CSF
Beschrijving

Specialized technique to collect CSF cells with preserved morphology; used to detect malignant cells.

Datatype

text

Alias
UMLS CUI [1,1]
C0456521
UMLS CUI [1,2]
C0007806
Glucose, CSF
Beschrijving

Measures glucose level in CSF; dependent on blood level (normally 60 to 80% of blood level)

Datatype

float

Maateenheden
  • mg/dL
Alias
UMLS CUI [1,1]
C0202042
UMLS CUI [1,2]
C0007806
mg/dL
IgG, CSF
Beschrijving

Quantitative IgG level in CSF.

Datatype

float

Maateenheden
  • mg/dL
Alias
UMLS CUI [1,1]
C0202087
UMLS CUI [1,2]
C0007806
mg/dL
IgG Index, CSF
Beschrijving

Measures intrathecal IgG production. Derived from ratio of CSF IgG to CSF albumin compared to serum IgG to serum albumin ratio (quantitative abnormality).

Datatype

float

Maateenheden
  • mg/dL
Alias
UMLS CUI [1,1]
C0202087
UMLS CUI [1,2]
C0007806
mg/dL
Immunofixation Electrophoresis, Serum
Beschrijving

Proteins are separated by electrophoresis, and then immune reactions are used to visualize and identify proteins.

Datatype

text

Alias
UMLS CUI [1,1]
C1611269
UMLS CUI [1,2]
C0229671
Lyme Disease Ab, CSF
Beschrijving

Positive; Negative. Immunoglobulin reactivity to B Burgdorferi. Measured by ELISA and/or Western blot.

Datatype

text

Alias
UMLS CUI [1,1]
C0024198
UMLS CUI [1,2]
C0007806
MRZ Reaction
Beschrijving

May be decreased by treatments that change intrathecal immunoglobulin production. Antibody index, q-specific versus the q IgG, localized in spinal fluid; 1.5 cutoff.

Datatype

text

Oligoclonal Banding, CSF
Beschrijving

Positive; Negative. Two or more discrete IgG electrophoretic bands in CSF not in serum. Reflects restricted intrathecal IgG production (qualitative abnormality).

Datatype

text

Alias
UMLS CUI [1]
C0201942
Protein, CSF
Beschrijving

Measures total protein level in CSF predominantly albumin; reflects serum proteins with trace CNS components and intrathecal modified components.

Datatype

float

Maateenheden
  • mg/dL
Alias
UMLS CUI [1]
C0201943
mg/dL
Red Blood Cell Count, CSF
Beschrijving

Erythrocytes detected in CSF, RBCs per mm3.

Datatype

float

Maateenheden
  • cells/mm3
Alias
UMLS CUI [1]
C3888459
cells/mm3
VDRL, CSF
Beschrijving

Positive; Negative. Nonspecific serologic test for syphilis; Venereal Disease Research Laboratory test is used to screen CSF for reagin antibodies diagnostic for neurosyphyilis.

Datatype

text

Alias
UMLS CUI [1]
C0236336
CSF Antibodies against CNS antigens
Beschrijving

Detection of CSG antibodies directed against a specific CNS autoantigen target.

Datatype

text

CSF CXCL13
Beschrijving

Quantitative measure of CXCL13 chemokine levels in CSF.

Datatype

float

Maateenheden
  • pg
Alias
UMLS CUI [1]
C3847043
pg
CSF cytokines and chemokines
Beschrijving

Quantitative detection of levels of a specific cytokine/chemokine in CSF.

Datatype

text

Alias
UMLS CUI [1,1]
C0010813
UMLS CUI [1,2]
C0282554
UMLS CUI [1,3]
C0007806
CSF glial fibrillary acidic protein (GFAP)
Beschrijving

Quantitative measure of soluble GFAP in CSF.

Datatype

text

Maateenheden
  • ng/mL
Alias
UMLS CUI [1,1]
C0017626
UMLS CUI [1,2]
C0007806
ng/mL
CSF IgM index
Beschrijving

Measures intrathecal IgM production. Derived from ratio of CSF IgM to CSF albumin compared to serum IgM to serum albumin.

Datatype

float

Maateenheden
  • mg/dL
Alias
UMLS CUI [1]
C1628437
mg/dL
CSF immunophenotyping by FACS
Beschrijving

CSF cell population identification by antigens expressed by the cells, detected by specific antibodies.

Datatype

text

Alias
UMLS CUI [1,1]
C0079611
UMLS CUI [1,2]
C0007806
CSF kappa
Beschrijving

Quantitative measure of kappa free light chains in CSF.

Datatype

text

Alias
UMLS CUI [1]
C1954403
CSF myelin basic protein (MBP)
Beschrijving

Quantitative measure of detectable MBP like material in CSF.

Datatype

text

Alias
UMLS CUI [1]
C0364783
CSF neural cell adhesion molecule (NCAM)
Beschrijving

Quantitative measure of soluble NCAM in CSF.

Datatype

float

Maateenheden
  • ng/mL
Alias
UMLS CUI [1,1]
C0282587
UMLS CUI [1,2]
C0007806
ng/mL
CSF neurofilament light chains
Beschrijving

neurofilament CSF

Datatype

text

Alias
UMLS CUI [1,1]
C0027834
UMLS CUI [1,2]
C0007806
CSF NMO IgG
Beschrijving

IgG antibodies reacting to aquaporin 4. Biomarker for NMO Devic spectrum disorder.

Datatype

text

Alias
UMLS CUI [1]
C1830792
Tears OCB
Beschrijving

Qualitative detection of two or more IgG electrophoretic bands in tears but not blood.

Datatype

text

Table 4 – CSF Culture
Beschrijving

Table 4 – CSF Culture

Alias
UMLS CUI-1
C0430403
Bacterial, Fungal culture
Beschrijving

Cryptococcus neoformans antigen; Mycobacteria culture. Culture of CSF to identify presence of a bacterial or fungal pathogen.

Datatype

text

Alias
UMLS CUI [1]
C0430402
UMLS CUI [2]
C0200954
Sterile fluid culture
Beschrijving

Gram stain. No identification/growth of any microbial pathogen from CSF cultures.

Datatype

text

Alias
UMLS CUI [1]
C0367249
Terug naar het begin van de pagina

Similar models

Laboratory Tests Recommendations Table 3 – CSF and Table 4 – CSF Culture

1 Formulieren
Name
Type
Description | Question | Decode (Coded Value)
Datatype
Alias
Item Group
Table 3 – CSF
C0007806 (UMLS CUI-1)
Albumin
Item
Albumin index
float
C0201838 (UMLS CUI [1])
Albumin CSF
Item
Albumin, CSF
float
C0201838 (UMLS CUI [1,1])
C0007806 (UMLS CUI [1,2])
Cell count
Item
Cell count and Diff, CSF
float
C0007584 (UMLS CUI [1])
lactate CSF
Item
CSF lactate
float
C0202113 (UMLS CUI [1,1])
C0007806 (UMLS CUI [1,2])
PCR virus CSF
Item
CSF PCR for viruses
text
C0032520 (UMLS CUI [1,1])
C0042776 (UMLS CUI [1,2])
C0007806 (UMLS CUI [1,3])
Cytopathology CSF
Item
Cytopathology, CSF
text
C0456521 (UMLS CUI [1,1])
C0007806 (UMLS CUI [1,2])
Glucose CSF
Item
Glucose, CSF
float
C0202042 (UMLS CUI [1,1])
C0007806 (UMLS CUI [1,2])
IgG CSF
Item
IgG, CSF
float
C0202087 (UMLS CUI [1,1])
C0007806 (UMLS CUI [1,2])
IgG CSF
Item
IgG Index, CSF
float
C0202087 (UMLS CUI [1,1])
C0007806 (UMLS CUI [1,2])
Immunofixation Electrophoresis Serum
Item
Immunofixation Electrophoresis, Serum
text
C1611269 (UMLS CUI [1,1])
C0229671 (UMLS CUI [1,2])
Lyme Disease CSF
Item
Lyme Disease Ab, CSF
text
C0024198 (UMLS CUI [1,1])
C0007806 (UMLS CUI [1,2])
MRZ Reaction
Item
MRZ Reaction
text
Oligoclonal Banding CSF
Item
Oligoclonal Banding, CSF
text
C0201942 (UMLS CUI [1])
Protein, CSF
Item
Protein, CSF
float
C0201943 (UMLS CUI [1])
Red Blood Cell Count, CSF
Item
Red Blood Cell Count, CSF
float
C3888459 (UMLS CUI [1])
VDRL, CSF
Item
VDRL, CSF
text
C0236336 (UMLS CUI [1])
CSF Antibodies against CNS antigens
Item
CSF Antibodies against CNS antigens
text
CSF CXCL13
Item
CSF CXCL13
float
C3847043 (UMLS CUI [1])
cytokines chemokines CSF
Item
CSF cytokines and chemokines
text
C0010813 (UMLS CUI [1,1])
C0282554 (UMLS CUI [1,2])
C0007806 (UMLS CUI [1,3])
Glial Fibrillary Acidic Protein CSF
Item
CSF glial fibrillary acidic protein (GFAP)
text
C0017626 (UMLS CUI [1,1])
C0007806 (UMLS CUI [1,2])
CSF IgM
Item
CSF IgM index
float
C1628437 (UMLS CUI [1])
Immunophenotyping CSF
Item
CSF immunophenotyping by FACS
text
C0079611 (UMLS CUI [1,1])
C0007806 (UMLS CUI [1,2])
CSF kappa
Item
CSF kappa
text
C1954403 (UMLS CUI [1])
CSF myelin basic protein
Item
CSF myelin basic protein (MBP)
text
C0364783 (UMLS CUI [1])
Neural Cell Adhesion Molecules CSF
Item
CSF neural cell adhesion molecule (NCAM)
float
C0282587 (UMLS CUI [1,1])
C0007806 (UMLS CUI [1,2])
neurofilament CSF
Item
CSF neurofilament light chains
text
C0027834 (UMLS CUI [1,1])
C0007806 (UMLS CUI [1,2])
CSF NMO IgG
Item
CSF NMO IgG
text
C1830792 (UMLS CUI [1])
Tears OCB
Item
Tears OCB
text
Item Group
Table 4 – CSF Culture
C0430403 (UMLS CUI-1)
Bacterial culture; Fungal culture
Item
Bacterial, Fungal culture
text
C0430402 (UMLS CUI [1])
C0200954 (UMLS CUI [2])
Sterile fluid culture
Item
Sterile fluid culture
text
C0367249 (UMLS CUI [1])
Terug naar het begin van de pagina 

Contact

Gebruik dit formulier voor feedback, vragen en verbeteringsvoorstellen.

Velden gemarkeerd met een * zijn verplicht.

Help

Do you need help on how to use the search function? Please watch the corresponding tutorial video for more details and learn how to use the search function most efficiently.

Watch Tutorial