ID

13914

Description

Background and Purpose: The purpose of the DESCRIBE study is to document the natural course of diseases in context of medical care of neurodegenerative disorders as well as cerebrovascular diseases and to perform phenotyping of the test persons. Disease-spanning analyses of the measured clincial data, the results of the imaging processes, results of the analysis of the biometerials including genetic analysis are planed. Principal Investigator: Prof. Klockgether, Dr. Spottke DZNE, Bonn. Source: DESCRIBE-Studie http://www.dzne.de/forschung/forschungsbereiche/klinische-forschung/studien/describe-bn006.html Participating Study Sites: Berlin, Bonn, Göttingen, Dresden, Köln, Magdeburg, München, Rostock/Greifswald, Tübingen

Link

http://www.dzne.de/forschung/forschungsbereiche/klinische-forschung/studien/describe-bn006.html

Keywords

  1. 3/15/16 3/15/16 -
  2. 3/16/16 3/16/16 -
Uploaded on

March 16, 2016

DOI

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License

Creative Commons BY-NC 3.0

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DESCRIBE (DZNE – Clinical Register Study of neurodegenerative Disorders) CRF Continuous Documentation

CRF Continuous Documentation

Diseases
Description

Diseases

Alias
UMLS CUI-1
C0012634
Study-ID:
Description

study id

Data type

text

Alias
UMLS CUI [1]
C2826693
Does the participant have any pre-existing conditions or comorbidities?
Description

If 'yes' please fill-out the following table

Data type

boolean

Alias
UMLS CUI [1]
C0521987
UMLS CUI [2]
C0009488
Documentation of diseases
Description

Documentation of diseases

No.
Description

no of diagnosis

Data type

integer

Alias
UMLS CUI [1,1]
C0237753
UMLS CUI [1,2]
C0011900
Diagnosis
Description

Please regard the following diagnoses: Hypertension, diabetes mellitus, hypercholesterolemia, stroke, epilepsy, heart attack, recurrent depressive episode, neoplasms, thyroid disease, renal insufficiency. You can use the checklist pre-existing condition. In the database one can choose the ICD-Code after data entry.

Data type

text

Alias
UMLS CUI [1]
C0011900
Onset of disease
Description

onset of disease

Data type

date

Alias
UMLS CUI [1]
C0277793
End of disease
Description

end of disease

Data type

date

Alias
UMLS CUI [1]
C4019088
Disease enduring
Description

enduring

Data type

boolean

Alias
UMLS CUI [1]
C1314677
Checklist pre-existing conditions
Description

Checklist pre-existing conditions

No. 1 Hypertension
Description

hypertension diagnosed

Data type

text

Alias
UMLS CUI [1]
C0020538
Initial diagnosis
Description

date initial diagnosis hypertension

Data type

date

Alias
UMLS CUI [1,1]
C0020538
UMLS CUI [1,2]
C2316983
No.2 Hypercholesterolemia
Description

hypercholesterolemia

Data type

text

Alias
UMLS CUI [1]
C0020443
Initial diagnosis
Description

date initial diagnosis hypercholesterolemia

Data type

date

Alias
UMLS CUI [1,1]
C0020443
UMLS CUI [1,2]
C2316983
No.3 Hypertriglyceridemia
Description

hypertriglyceridemia

Data type

text

Alias
UMLS CUI [1]
C0020557
Initial diagnosis
Description

date initial diagnosis hypertriglyceridemia

Data type

date

Alias
UMLS CUI [1,1]
C0020557
UMLS CUI [1,2]
C2316983
No.4 Other hyperlipedimia or dyslipidemia
Description

hyperlipedimia or dyslipidemia

Data type

text

Alias
UMLS CUI [1]
C0020473
UMLS CUI [2]
C0242339
Initial diagnosis
Description

initial diagnosis of hyperlipedimia or dyslipedimia

Data type

date

Alias
UMLS CUI [1,1]
C0020473
UMLS CUI [1,2]
C2316983
UMLS CUI [2,1]
C0242339
UMLS CUI [2,2]
C2316983
No. 5 Diabetes mellitus type 1
Description

diabetes mellitus type 1

Data type

text

Alias
UMLS CUI [1]
C0011854
Initial diagnosis
Description

initial diagnosis of diabetes type 1

Data type

date

Alias
UMLS CUI [1,1]
C0011854
UMLS CUI [1,2]
C2316983
No. 6 Diabetes mellitus type 2
Description

diabetes mellitus type 2

Data type

text

Alias
UMLS CUI [1]
C0011860
Initial diagnosis
Description

initial diagnosis of diabetes type 2

Data type

date

Alias
UMLS CUI [1,1]
C0011860
UMLS CUI [1,2]
C2316983
No. 7 Diabetic polyneuropathy
Description

diabetic polyneuropathy

Data type

text

Alias
UMLS CUI [1]
C0271680
Initial diagnosis
Description

initial diagnosis of diabetic polyneuropathy

Data type

date

Alias
UMLS CUI [1,1]
C0271680
UMLS CUI [1,2]
C2316983
No. 8 Cardiac infarction
Description

cardiac infarction

Data type

text

Alias
UMLS CUI [1]
C0027051
Initial diagnosis
Description

date of initial diagnosis cardiac infarction

Data type

date

Alias
UMLS CUI [1,1]
C0027051
UMLS CUI [1,2]
C2316983
No.9 Transient ischemic attack (TIA)
Description

transient ischemic attack

Data type

text

Alias
UMLS CUI [1]
C0007787
Initial diagnosis
Description

date of initial diagnosis TIA

Data type

date

Alias
UMLS CUI [1,1]
C0007787
UMLS CUI [1,2]
C2316983
No. 10 Coronary heart disease
Description

coronary heart disease

Data type

text

Alias
UMLS CUI [1]
C0010068
Initial diagnosis
Description

date of initial diagnosis coronary heart disease

Data type

date

Alias
UMLS CUI [1,1]
C0010068
UMLS CUI [1,2]
C2316983
No. 11 Stroke (ischemic)
Description

stroke

Data type

text

Alias
UMLS CUI [1]
C0038454
Initial diagnosis
Description

date of initial diagnosis stroke

Data type

date

Alias
UMLS CUI [1,1]
C0038454
UMLS CUI [1,2]
C2316983
No. 12 Cerebral venous sinus thrombosis or cerebral thrombosis
Description

cerebral venous sinus thrombosis or cerebral thrombosis

Data type

text

Alias
UMLS CUI [1]
C0338573
UMLS CUI [2]
C0079102
Initial date
Description

date of initial diagnosis cerebral venous sinus thrombosis

Data type

date

Alias
UMLS CUI [1,1]
C0338573
UMLS CUI [1,2]
C2316983
UMLS CUI [2,1]
C0079102
UMLS CUI [2,2]
C2316983
No. 13 Subarachnoid hemorrhage
Description

subarachnoid hemorrhage

Data type

text

Alias
UMLS CUI [1]
C0038525
Initial diagnosis
Description

date of initial diagnosis SAB

Data type

date

Alias
UMLS CUI [1,1]
C0038525
UMLS CUI [1,2]
C2316983
No. 14 Intracerebral hemorrhage (ICH)
Description

ICH

Data type

text

Alias
UMLS CUI [1]
C2937358
Initial diagnosis
Description

date of initial diagnosis ICH

Data type

date

Alias
UMLS CUI [1,1]
C2937358
UMLS CUI [1,2]
C2316983
No. 15 Subdural hematoma
Description

subdural hematoma

Data type

text

Alias
UMLS CUI [1]
C0018946
Initial diagnosis
Description

date of initial diagnosis subdural hematoma

Data type

date

Alias
UMLS CUI [1,1]
C0018946
UMLS CUI [1,2]
C2316983
No. 16 Concussion
Description

concussion

Data type

text

Alias
UMLS CUI [1]
C0006107
Initial diagnosis
Description

date of initial diagnosis concussion

Data type

date

Alias
UMLS CUI [1,1]
C0006107
UMLS CUI [1,2]
C2316983
No. 17 Other pre-existing brain condition
Description

other pre-existing brain condition

Data type

text

Alias
UMLS CUI [1,1]
C0006111
UMLS CUI [1,2]
C2347662
UMLS CUI [1,3]
C0205394
Initial diagnosis
Description

date of initial diagnosis other pre-existing brain condition

Data type

date

Alias
UMLS CUI [1,1]
C0006111
UMLS CUI [1,2]
C2347662
UMLS CUI [1,3]
C0205394
UMLS CUI [1,4]
C2316983
No. 18 Peripheral arterial disease
Description

peripheral arterial disease

Data type

text

Alias
UMLS CUI [1]
C1704436
Initial diagnosis
Description

date of initial diagnosis PAD

Data type

date

Alias
UMLS CUI [1,1]
C1704436
UMLS CUI [1,2]
C2316983
No. 19 Atrial fibrillation
Description

atrial fibrillation

Data type

text

Alias
UMLS CUI [1]
C0004238
Initial diagnosis
Description

date of initial diagnosis atrial fillibration

Data type

date

Alias
UMLS CUI [1,1]
C0004238
UMLS CUI [1,2]
C2316983
No. 20 Hemophilia
Description

hemophilia

Data type

text

Alias
UMLS CUI [1]
C0684275
Initial diagnosis
Description

date of initial diagnosis hemophilia

Data type

date

Alias
UMLS CUI [1,1]
C0684275
UMLS CUI [1,2]
C2316983
No. 21 Parkinson's disease
Description

parkinsons disease

Data type

text

Alias
UMLS CUI [1]
C0030567
Initial diagnosis
Description

date of initial diagnosis PD

Data type

date

Alias
UMLS CUI [1,1]
C0030567
UMLS CUI [1,2]
C2316983
No. 22 Rheumatism or arthritis
Description

rheumatism or arthritis

Data type

text

Alias
UMLS CUI [1]
C0035435
UMLS CUI [2]
C0003864
Initial diagnosis
Description

date of initial diagnosis rheumatism or arthritis

Data type

date

Alias
UMLS CUI [1,1]
C0035435
UMLS CUI [1,2]
C2316983
UMLS CUI [2,1]
C0003864
UMLS CUI [2,2]
C2316983
No. 23 Hypersensitivity
Description

allergies

Data type

text

Alias
UMLS CUI [1]
C0020517
Initial diagnosis
Description

date of initial diagnosis hypersensitivity

Data type

date

Alias
UMLS CUI [1,1]
C0020517
UMLS CUI [1,2]
C2316983
Procedures
Description

Procedures

Alias
UMLS CUI-1
C0087111
Did the participant receive one or several treatments in the past?
Description

If 'Yes', please fill out the following table.

Data type

text

Documentation of procedures
Description

Documentation of procedures

No.
Description

number of procedure

Data type

integer

Alias
UMLS CUI [1,1]
C0237753
UMLS CUI [1,2]
C0087111
Procedure
Description

Please regard implantation of cardiac pacemaker, tissue transplantation, blood transfusion, giving birth and joint replacement.

Data type

text

Alias
UMLS CUI [1]
C0087111
Indication
Description

indication of procedure

Data type

text

Alias
UMLS CUI [1,1]
C0087111
UMLS CUI [1,2]
C0392360
Date of procedure
Description

Date of procedure

Data type

date

Alias
UMLS CUI [1]
C2584899
Medication
Description

Medication

Alias
UMLS CUI-1
C0013227
Does the participant take any medication at the moment?
Description

current medication

Data type

text

Alias
UMLS CUI [1]
C1553892
Documentation of medication
Description

Documentation of medication

No.
Description

number of medication

Data type

integer

Alias
UMLS CUI [1,1]
C0237753
UMLS CUI [1,2]
C0013227
Medical drug/active agents
Description

medical drug

Data type

text

Alias
UMLS CUI [1]
C0013227
Daily dose
Description

daily dose

Data type

float

Alias
UMLS CUI [1]
C2348070
Unit
Description

daily dose unit

Data type

text

Alias
UMLS CUI [1]
C0869039
Type of application
Description

type of application

Data type

integer

Alias
UMLS CUI [1]
C0185125
Route of application
Description

route of application

Data type

integer

Alias
UMLS CUI [1]
C0013153
Indication
Description

indication of procedure

Data type

text

Alias
UMLS CUI [1,1]
C0087111
UMLS CUI [1,2]
C0392360
Duration - Start of procedure
Description

start of precedure

Data type

date

Alias
UMLS CUI [1]
C3897826
Duration - End of procedure
Description

end of procedure

Data type

date

Alias
UMLS CUI [1]
C3897842
Procedure enduring
Description

procedure enduring

Data type

boolean

Alias
UMLS CUI [1]
C1314677
Family history - family tree
Description

Family history - family tree

Alias
UMLS CUI-1
C1148543
Here you have the opportunity to draw a sketch of the family tree.
Description

sketch of family tree

Data type

text

Alias
UMLS CUI [1]
C1148543
Family history - parents
Description

Family history - parents

Alias
UMLS CUI-1
C0241889
Mother: Year of birth
Description

year of birth mother

Data type

integer

Alias
UMLS CUI [1]
C2319404
Screened diseases
Description

screened diseases

Data type

boolean

Alias
UMLS CUI [1,1]
C0012634
UMLS CUI [1,2]
C0018017
Alive?
Description

mother alive

Data type

text

Alias
UMLS CUI [1]
C2321272
Mother - Year of death
Description

if dead

Data type

integer

Alias
UMLS CUI [1,1]
C0425049
UMLS CUI [1,2]
C0439234
Unknown
Description

year of death mother unknown

Data type

boolean

Alias
UMLS CUI [1,1]
C0425049
UMLS CUI [1,2]
C0439234
UMLS CUI [1,3]
C0439673
Father - Year of birth
Description

year of birth father

Data type

integer

Alias
UMLS CUI [1]
C2136977
Screened diseases?
Description

screened disease father

Data type

boolean

Alias
UMLS CUI [1,1]
C0012634
UMLS CUI [1,2]
C0018017
Alive?
Description

father alive

Data type

text

Alias
UMLS CUI [1]
C2321271
Father - Year of death
Description

year of death father

Data type

integer

Alias
UMLS CUI [1,1]
C0425048
UMLS CUI [1,2]
C0439234
Unknown
Description

year of death father unknown

Data type

integer

Alias
UMLS CUI [1,1]
C0425048
UMLS CUI [1,2]
C0439234
UMLS CUI [1,3]
C0439673
Family history - siblings
Description

Family history - siblings

Sibling
Description

sibling gender

Data type

text

Alias
UMLS CUI [1,1]
C0037047
UMLS CUI [1,2]
C0079399
Sibling - Year of birth
Description

year of birth sibling

Data type

integer

Alias
UMLS CUI [1]
C2317653
UMLS CUI [2]
C2317746
Screened diseases?
Description

screened diseases sibling

Data type

boolean

Alias
UMLS CUI [1,1]
C0012634
UMLS CUI [1,2]
C0018017
Alive?
Description

sibling alive

Data type

text

Alias
UMLS CUI [1]
C2321274
UMLS CUI [2]
C2321284
Sibling - Year of death
Description

year of death sibling

Data type

integer

Alias
UMLS CUI [1,1]
C0524344
UMLS CUI [1,2]
C0439234
year of death sibling unknown
Description

year of death sibling unknown

Data type

boolean

Alias
UMLS CUI [1,1]
C0524344
UMLS CUI [1,2]
C0439234
UMLS CUI [1,3]
C0439673
Family history - children
Description

Family history - children

Child
Description

child gender

Data type

text

Alias
UMLS CUI [1,1]
C0008059
UMLS CUI [1,2]
C0079399
Child - Year of birth
Description

year of birth child

Data type

integer

Alias
UMLS CUI [1,1]
C2826771
UMLS CUI [1,2]
C0008059
Screened diseases?
Description

screened diseases child

Data type

boolean

Alias
UMLS CUI [1,1]
C0012634
UMLS CUI [1,2]
C0018017
Alive?
Description

child alive

Data type

text

Alias
UMLS CUI [1,1]
C0008059
UMLS CUI [1,2]
C2584946
Child - Year of death
Description

year of death child

Data type

integer

Alias
UMLS CUI [1,1]
C0524343
UMLS CUI [1,2]
C0439234
Unknown
Description

year of death child unknown

Data type

integer

Alias
UMLS CUI [1,1]
C0524343
UMLS CUI [1,2]
C0439234
UMLS CUI [1,3]
C0439673
Family history - further relatives
Description

Family history - further relatives

Degree of affinity
Description

degree of affinity

Data type

integer

Alias
UMLS CUI [1]
C0680204
Side
Description

degree of affinity side

Data type

text

Alias
UMLS CUI [1]
C0680204
Gender
Description

relative gender

Data type

text

Alias
UMLS CUI [1]
C3172261
Relative - Year of birth
Description

year of birth relative

Data type

integer

Alias
UMLS CUI [1,1]
C2826771
UMLS CUI [1,2]
C0080103
Screened diseases?
Description

screened diseases relative

Data type

boolean

Alias
UMLS CUI [1,1]
C0012634
UMLS CUI [1,2]
C0018017
Alive?
Description

relative alive

Data type

text

Alias
UMLS CUI [1]
C3172264
Relative - Year of death
Description

year of death relative

Data type

integer

Alias
UMLS CUI [1,1]
C0425043
UMLS CUI [1,2]
C0439234
Unknown
Description

year of relative unknown

Data type

boolean

Alias
UMLS CUI [1,1]
C0425043
UMLS CUI [1,2]
C0439234
UMLS CUI [1,3]
C0439673
Family history - relatives with screened diseases
Description

Family history - relatives with screened diseases

Degree of affinity
Description

degree of affinity

Data type

integer

Alias
UMLS CUI [1]
C0680204
Side
Description

degree of affinity side

Data type

text

Alias
UMLS CUI [1]
C0680204
Gender
Description

gender relative

Data type

text

Alias
UMLS CUI [1]
C3172261
Year of birth
Description

relative year of birth

Data type

integer

Alias
UMLS CUI [1,1]
C2826771
UMLS CUI [1,2]
C0080103
Diagnosis
Description

diagnosis

Data type

integer

Alias
UMLS CUI [1]
C0011900
Verified?
Description

verified

Data type

integer

Alias
UMLS CUI [1]
C1711411
Age at onset on symptoms
Description

age at onset of symptoms

Data type

integer

Alias
UMLS CUI [1]
C0150907
Register?
Description

register

Data type

boolean

Alias
UMLS CUI [1]
C0585825
Participant-ID
Description

If 'registered'

Data type

text

Alias
UMLS CUI [1]
C1300638
Handedness
Description

Handedness

Which hand do you use to write a legible letter?
Description

hand to write letter

Data type

text

Alias
UMLS CUI [1]
C2734042
Which hand do you use to throw a ball?
Description

hand to throw a ball

Data type

text

Alias
UMLS CUI [1]
C2734034
Which hand do you use to play with a racket in a game?
Description

hand to play

Data type

text

Alias
UMLS CUI [1]
C2734048
Which hand do you use as upper hand using a broom?
Description

hand to use broom

Data type

text

Alias
UMLS CUI [1,1]
C0023114
UMLS CUI [1,2]
C3843854
Which hand do you use as upper hand to use a spade snow shoveling?
Description

hand snow shoveling

Data type

text

Alias
UMLS CUI [1,1]
C0023114
UMLS CUI [1,2]
C2712668
Which hand do you use to strike a match?
Description

hand to strike a match

Data type

text

Alias
UMLS CUI [1]
C2734054
Which hand do you use to hold the scissors cutting?
Description

hand to hold scissors

Data type

text

Alias
UMLS CUI [1,1]
C0023114
UMLS CUI [1,2]
C0175735
Which do you use to thread a needle?
Description

hand to thread a needle

Data type

text

Alias
UMLS CUI [1]
C2734060
Which hand do you use to deal cards?
Description

hand to deal cards

Data type

text

Alias
UMLS CUI [1]
C2734058
Which hand do you use to hold a hammer nailing?
Description

hand to hold hammer

Data type

text

Alias
UMLS CUI [1]
C2734052
Which hand do you use to hold a toothbrush?
Description

hand to hold toothbrush

Data type

text

Alias
UMLS CUI [1]
C2734038
Which hand do you use to open a bottle?
Description

hand to open bottle

Data type

text

Alias
UMLS CUI [1,1]
C0023114
UMLS CUI [1,2]
C0179376
Which eye do you use, if you can only use one eye (e.g. keyhole)?
Description

eye dominance

Data type

text

Alias
UMLS CUI [1]
C0422883
Overview - Study participation
Description

Overview - Study participation

Study abbreviation (Study number)
Description

e.g. DELCODE (BN012)

Data type

text

Alias
UMLS CUI [1]
C2826693
Date of consent
Description

date of consent

Data type

date

Alias
UMLS CUI [1]
C2985782
Date end of study
Description

date end of study

Data type

date

Alias
UMLS CUI [1]
C2983670

Similar models

CRF Continuous Documentation

Name
Type
Description | Question | Decode (Coded Value)
Data type
Alias
Item Group
Diseases
C0012634 (UMLS CUI-1)
study id
Item
Study-ID:
text
C2826693 (UMLS CUI [1])
pre-existing codition and comorbidities
Item
Does the participant have any pre-existing conditions or comorbidities?
boolean
C0521987 (UMLS CUI [1])
C0009488 (UMLS CUI [2])
Item Group
Documentation of diseases
no of diagnosis
Item
No.
integer
C0237753 (UMLS CUI [1,1])
C0011900 (UMLS CUI [1,2])
diagnosis
Item
Diagnosis
text
C0011900 (UMLS CUI [1])
onset of disease
Item
Onset of disease
date
C0277793 (UMLS CUI [1])
end of disease
Item
End of disease
date
C4019088 (UMLS CUI [1])
enduring
Item
Disease enduring
boolean
C1314677 (UMLS CUI [1])
Item Group
Checklist pre-existing conditions
Item
No. 1 Hypertension
text
C0020538 (UMLS CUI [1])
Code List
No. 1 Hypertension
CL Item
Yes  (Yes )
CL Item
No  (No )
CL Item
Unknown (Unknown)
CL Item
Not specified (Not specified)
date initial diagnosis hypertension
Item
Initial diagnosis
date
C0020538 (UMLS CUI [1,1])
C2316983 (UMLS CUI [1,2])
Item
No.2 Hypercholesterolemia
text
C0020443 (UMLS CUI [1])
Code List
No.2 Hypercholesterolemia
CL Item
Yes  (Yes )
CL Item
No  (No )
CL Item
Unknown (Unknown)
CL Item
Not specified (Not specified)
date initial diagnosis hypercholesterolemia
Item
Initial diagnosis
date
C0020443 (UMLS CUI [1,1])
C2316983 (UMLS CUI [1,2])
Item
No.3 Hypertriglyceridemia
text
C0020557 (UMLS CUI [1])
Code List
No.3 Hypertriglyceridemia
CL Item
Yes  (Yes )
CL Item
No  (No )
CL Item
Unknown (Unknown)
CL Item
Not specified (Not specified)
date initial diagnosis hypertriglyceridemia
Item
Initial diagnosis
date
C0020557 (UMLS CUI [1,1])
C2316983 (UMLS CUI [1,2])
Item
No.4 Other hyperlipedimia or dyslipidemia
text
C0020473 (UMLS CUI [1])
C0242339 (UMLS CUI [2])
Code List
No.4 Other hyperlipedimia or dyslipidemia
CL Item
Yes  (Yes )
CL Item
No  (No )
CL Item
Unknown (Unknown)
CL Item
Not specified (Not specified)
initial diagnosis of hyperlipedimia or dyslipedimia
Item
Initial diagnosis
date
C0020473 (UMLS CUI [1,1])
C2316983 (UMLS CUI [1,2])
C0242339 (UMLS CUI [2,1])
C2316983 (UMLS CUI [2,2])
Item
No. 5 Diabetes mellitus type 1
text
C0011854 (UMLS CUI [1])
Code List
No. 5 Diabetes mellitus type 1
CL Item
Yes  (Yes )
CL Item
No  (No )
CL Item
Unknown (Unknown)
CL Item
Not specified (Not specified)
initial diagnosis of diabetes type 1
Item
Initial diagnosis
date
C0011854 (UMLS CUI [1,1])
C2316983 (UMLS CUI [1,2])
Item
No. 6 Diabetes mellitus type 2
text
C0011860 (UMLS CUI [1])
Code List
No. 6 Diabetes mellitus type 2
CL Item
Yes  (Yes )
CL Item
No  (No )
CL Item
Unknown (Unknown)
CL Item
Not specified (Not specified)
initial diagnosis of diabetes type 2
Item
Initial diagnosis
date
C0011860 (UMLS CUI [1,1])
C2316983 (UMLS CUI [1,2])
Item
No. 7 Diabetic polyneuropathy
text
C0271680 (UMLS CUI [1])
Code List
No. 7 Diabetic polyneuropathy
CL Item
Yes  (Yes )
CL Item
No  (No )
CL Item
Unknown (Unknown)
CL Item
Not specified (Not specified)
initial diagnosis of diabetic polyneuropathy
Item
Initial diagnosis
date
C0271680 (UMLS CUI [1,1])
C2316983 (UMLS CUI [1,2])
Item
No. 8 Cardiac infarction
text
C0027051 (UMLS CUI [1])
Code List
No. 8 Cardiac infarction
CL Item
Yes  (Yes )
CL Item
No  (No )
CL Item
Unknown (Unknown)
CL Item
Not specified (Not specified)
date of initial diagnosis cardiac infarction
Item
Initial diagnosis
date
C0027051 (UMLS CUI [1,1])
C2316983 (UMLS CUI [1,2])
Item
No.9 Transient ischemic attack (TIA)
text
C0007787 (UMLS CUI [1])
Code List
No.9 Transient ischemic attack (TIA)
CL Item
Yes  (Yes )
CL Item
No  (No )
CL Item
Unknown (Unknown)
CL Item
Not specified (Not specified)
date of initial diagnosis TIA
Item
Initial diagnosis
date
C0007787 (UMLS CUI [1,1])
C2316983 (UMLS CUI [1,2])
Item
No. 10 Coronary heart disease
text
C0010068 (UMLS CUI [1])
Code List
No. 10 Coronary heart disease
CL Item
Yes  (Yes )
CL Item
No  (No )
CL Item
Unknown (Unknown)
CL Item
Not specified (Not specified)
date of initial diagnosis coronary heart disease
Item
Initial diagnosis
date
C0010068 (UMLS CUI [1,1])
C2316983 (UMLS CUI [1,2])
Item
No. 11 Stroke (ischemic)
text
C0038454 (UMLS CUI [1])
Code List
No. 11 Stroke (ischemic)
CL Item
Yes  (Yes )
CL Item
No  (No )
CL Item
Unknown (Unknown)
CL Item
Not specified (Not specified)
date of initial diagnosis stroke
Item
Initial diagnosis
date
C0038454 (UMLS CUI [1,1])
C2316983 (UMLS CUI [1,2])
Item
No. 12 Cerebral venous sinus thrombosis or cerebral thrombosis
text
C0338573 (UMLS CUI [1])
C0079102 (UMLS CUI [2])
Code List
No. 12 Cerebral venous sinus thrombosis or cerebral thrombosis
CL Item
Yes  (Yes )
CL Item
No  (No )
CL Item
Unknown (Unknown)
CL Item
Not specified (Not specified)
date of initial diagnosis cerebral venous sinus thrombosis
Item
Initial date
date
C0338573 (UMLS CUI [1,1])
C2316983 (UMLS CUI [1,2])
C0079102 (UMLS CUI [2,1])
C2316983 (UMLS CUI [2,2])
Item
No. 13 Subarachnoid hemorrhage
text
C0038525 (UMLS CUI [1])
Code List
No. 13 Subarachnoid hemorrhage
CL Item
Yes  (Yes )
CL Item
No  (No )
CL Item
Unknown (Unknown)
CL Item
Not specified (Not specified)
date of initial diagnosis SAB
Item
Initial diagnosis
date
C0038525 (UMLS CUI [1,1])
C2316983 (UMLS CUI [1,2])
Item
No. 14 Intracerebral hemorrhage (ICH)
text
C2937358 (UMLS CUI [1])
Code List
No. 14 Intracerebral hemorrhage (ICH)
CL Item
Yes  (Yes )
CL Item
No  (No )
CL Item
Unknown (Unknown)
CL Item
Not specified (Not specified)
date of initial diagnosis ICH
Item
Initial diagnosis
date
C2937358 (UMLS CUI [1,1])
C2316983 (UMLS CUI [1,2])
Item
No. 15 Subdural hematoma
text
C0018946 (UMLS CUI [1])
Code List
No. 15 Subdural hematoma
CL Item
Yes  (Yes )
CL Item
No  (No )
CL Item
Unknown (Unknown)
CL Item
Not specified (Not specified)
date of initial diagnosis subdural hematoma
Item
Initial diagnosis
date
C0018946 (UMLS CUI [1,1])
C2316983 (UMLS CUI [1,2])
Item
No. 16 Concussion
text
C0006107 (UMLS CUI [1])
Code List
No. 16 Concussion
CL Item
Yes  (Yes )
CL Item
No  (No )
CL Item
Unknown (Unknown)
CL Item
Not specified (Not specified)
date of initial diagnosis concussion
Item
Initial diagnosis
date
C0006107 (UMLS CUI [1,1])
C2316983 (UMLS CUI [1,2])
Item
No. 17 Other pre-existing brain condition
text
C0006111 (UMLS CUI [1,1])
C2347662 (UMLS CUI [1,2])
C0205394 (UMLS CUI [1,3])
Code List
No. 17 Other pre-existing brain condition
CL Item
Yes  (Yes )
CL Item
No  (No )
CL Item
Unknown (Unknown)
CL Item
Not specified (Not specified)
date of initial diagnosis other pre-existing brain condition
Item
Initial diagnosis
date
C0006111 (UMLS CUI [1,1])
C2347662 (UMLS CUI [1,2])
C0205394 (UMLS CUI [1,3])
C2316983 (UMLS CUI [1,4])
Item
No. 18 Peripheral arterial disease
text
C1704436 (UMLS CUI [1])
Code List
No. 18 Peripheral arterial disease
CL Item
Yes  (Yes )
CL Item
No  (No )
CL Item
Unknown (Unknown)
CL Item
Not specified (Not specified)
date of initial diagnosis PAD
Item
Initial diagnosis
date
C1704436 (UMLS CUI [1,1])
C2316983 (UMLS CUI [1,2])
Item
No. 19 Atrial fibrillation
text
C0004238 (UMLS CUI [1])
Code List
No. 19 Atrial fibrillation
CL Item
Yes  (Yes )
CL Item
No  (No )
CL Item
Unknown (Unknown)
CL Item
Not specified (Not specified)
date of initial diagnosis atrial fillibration
Item
Initial diagnosis
date
C0004238 (UMLS CUI [1,1])
C2316983 (UMLS CUI [1,2])
Item
No. 20 Hemophilia
text
C0684275 (UMLS CUI [1])
Code List
No. 20 Hemophilia
CL Item
Yes  (Yes )
CL Item
No  (No )
CL Item
Unknown (Unknown)
CL Item
Not specified (Not specified)
date of initial diagnosis hemophilia
Item
Initial diagnosis
date
C0684275 (UMLS CUI [1,1])
C2316983 (UMLS CUI [1,2])
Item
No. 21 Parkinson's disease
text
C0030567 (UMLS CUI [1])
Code List
No. 21 Parkinson's disease
CL Item
Yes  (Yes )
CL Item
No  (No )
CL Item
Unknown (Unknown)
CL Item
Not specified (Not specified)
date of initial diagnosis PD
Item
Initial diagnosis
date
C0030567 (UMLS CUI [1,1])
C2316983 (UMLS CUI [1,2])
Item
No. 22 Rheumatism or arthritis
text
C0035435 (UMLS CUI [1])
C0003864 (UMLS CUI [2])
Code List
No. 22 Rheumatism or arthritis
CL Item
Yes  (Yes )
CL Item
No  (No )
CL Item
Unknown (Unknown)
CL Item
Not specified (Not specified)
date of initial diagnosis rheumatism or arthritis
Item
Initial diagnosis
date
C0035435 (UMLS CUI [1,1])
C2316983 (UMLS CUI [1,2])
C0003864 (UMLS CUI [2,1])
C2316983 (UMLS CUI [2,2])
Item
No. 23 Hypersensitivity
text
C0020517 (UMLS CUI [1])
Code List
No. 23 Hypersensitivity
CL Item
Yes  (Yes )
CL Item
No  (No )
CL Item
Unknown (Unknown)
CL Item
Not specified (Not specified)
date of initial diagnosis hypersensitivity
Item
Initial diagnosis
date
C0020517 (UMLS CUI [1,1])
C2316983 (UMLS CUI [1,2])
Item Group
Procedures
C0087111 (UMLS CUI-1)
Item
Did the participant receive one or several treatments in the past?
text
Code List
Did the participant receive one or several treatments in the past?
CL Item
Yes (Yes)
CL Item
No  (No )
CL Item
Unknown (Unknown)
Item Group
Documentation of procedures
number of procedure
Item
No.
integer
C0237753 (UMLS CUI [1,1])
C0087111 (UMLS CUI [1,2])
procedure
Item
Procedure
text
C0087111 (UMLS CUI [1])
indication of procedure
Item
Indication
text
C0087111 (UMLS CUI [1,1])
C0392360 (UMLS CUI [1,2])
Date of procedure
Item
Date of procedure
date
C2584899 (UMLS CUI [1])
Item Group
Medication
C0013227 (UMLS CUI-1)
Item
Does the participant take any medication at the moment?
text
C1553892 (UMLS CUI [1])
Code List
Does the participant take any medication at the moment?
CL Item
Yes (Yes)
CL Item
No  (No )
CL Item
Unknown (Unknown)
Item Group
Documentation of medication
number of medication
Item
No.
integer
C0237753 (UMLS CUI [1,1])
C0013227 (UMLS CUI [1,2])
medical drug
Item
Medical drug/active agents
text
C0013227 (UMLS CUI [1])
daily dose
Item
Daily dose
float
C2348070 (UMLS CUI [1])
daily dose unit
Item
Unit
text
C0869039 (UMLS CUI [1])
Item
Type of application
integer
C0185125 (UMLS CUI [1])
Code List
Type of application
CL Item
tablet (1)
CL Item
cream (2)
CL Item
spray (3)
CL Item
syringe (4)
CL Item
suppository (5)
CL Item
drops (6)
CL Item
infusion (7)
CL Item
transdermal (8)
CL Item
other (9)
Item
Route of application
integer
C0013153 (UMLS CUI [1])
Code List
Route of application
CL Item
per os (1)
CL Item
intravenous (2)
CL Item
intramuscular (3)
CL Item
subcutaneous (4)
CL Item
rectal (5)
CL Item
local (6)
CL Item
per inhalation (7)
CL Item
transdermal (8)
CL Item
other (9)
indication of procedure
Item
Indication
text
C0087111 (UMLS CUI [1,1])
C0392360 (UMLS CUI [1,2])
start of precedure
Item
Duration - Start of procedure
date
C3897826 (UMLS CUI [1])
end of procedure
Item
Duration - End of procedure
date
C3897842 (UMLS CUI [1])
procedure enduring
Item
Procedure enduring
boolean
C1314677 (UMLS CUI [1])
Item Group
Family history - family tree
C1148543 (UMLS CUI-1)
sketch of family tree
Item
Here you have the opportunity to draw a sketch of the family tree.
text
C1148543 (UMLS CUI [1])
Item Group
Family history - parents
C0241889 (UMLS CUI-1)
year of birth mother
Item
Mother: Year of birth
integer
C2319404 (UMLS CUI [1])
screened diseases
Item
Screened diseases
boolean
C0012634 (UMLS CUI [1,1])
C0018017 (UMLS CUI [1,2])
Item
Alive?
text
C2321272 (UMLS CUI [1])
Code List
Alive?
CL Item
Yes (Yes)
CL Item
No  (No )
CL Item
Unknown (Unknown)
year of death mother
Item
Mother - Year of death
integer
C0425049 (UMLS CUI [1,1])
C0439234 (UMLS CUI [1,2])
year of death mother unknown
Item
Unknown
boolean
C0425049 (UMLS CUI [1,1])
C0439234 (UMLS CUI [1,2])
C0439673 (UMLS CUI [1,3])
year of birth father
Item
Father - Year of birth
integer
C2136977 (UMLS CUI [1])
screened disease father
Item
Screened diseases?
boolean
C0012634 (UMLS CUI [1,1])
C0018017 (UMLS CUI [1,2])
Item
Alive?
text
C2321271 (UMLS CUI [1])
Code List
Alive?
CL Item
Yes (Yes)
CL Item
No  (No )
CL Item
Unknown (Unknown)
year of death father
Item
Father - Year of death
integer
C0425048 (UMLS CUI [1,1])
C0439234 (UMLS CUI [1,2])
year of death father unknown
Item
Unknown
integer
C0425048 (UMLS CUI [1,1])
C0439234 (UMLS CUI [1,2])
C0439673 (UMLS CUI [1,3])
Item Group
Family history - siblings
Item
Sibling
text
C0037047 (UMLS CUI [1,1])
C0079399 (UMLS CUI [1,2])
Code List
Sibling
CL Item
brother (brother)
CL Item
sister (sister)
year of birth sibling
Item
Sibling - Year of birth
integer
C2317653 (UMLS CUI [1])
C2317746 (UMLS CUI [2])
screened diseases sibling
Item
Screened diseases?
boolean
C0012634 (UMLS CUI [1,1])
C0018017 (UMLS CUI [1,2])
Item
Alive?
text
C2321274 (UMLS CUI [1])
C2321284 (UMLS CUI [2])
Code List
Alive?
CL Item
Yes (Yes)
CL Item
No  (No )
CL Item
Unknown (Unknown)
year of death sibling
Item
Sibling - Year of death
integer
C0524344 (UMLS CUI [1,1])
C0439234 (UMLS CUI [1,2])
year of death sibling unknown
Item
boolean
C0524344 (UMLS CUI [1,1])
C0439234 (UMLS CUI [1,2])
C0439673 (UMLS CUI [1,3])
Item Group
Family history - children
Item
Child
text
C0008059 (UMLS CUI [1,1])
C0079399 (UMLS CUI [1,2])
Code List
Child
CL Item
daughter (daughter)
CL Item
son (son)
year of birth child
Item
Child - Year of birth
integer
C2826771 (UMLS CUI [1,1])
C0008059 (UMLS CUI [1,2])
screened diseases child
Item
Screened diseases?
boolean
C0012634 (UMLS CUI [1,1])
C0018017 (UMLS CUI [1,2])
Item
Alive?
text
C0008059 (UMLS CUI [1,1])
C2584946 (UMLS CUI [1,2])
Code List
Alive?
CL Item
Yes (Yes)
CL Item
No  (No )
CL Item
Unknown (Unknown)
year of death child
Item
Child - Year of death
integer
C0524343 (UMLS CUI [1,1])
C0439234 (UMLS CUI [1,2])
year of death child unknown
Item
Unknown
integer
C0524343 (UMLS CUI [1,1])
C0439234 (UMLS CUI [1,2])
C0439673 (UMLS CUI [1,3])
Item Group
Family history - further relatives
Item
Degree of affinity
integer
C0680204 (UMLS CUI [1])
Code List
Degree of affinity
CL Item
Great-Grandfather/Great-Grandmother (1)
CL Item
Grandfather/Grandmother (2)
CL Item
Granduncle/Grand-aunt (3)
CL Item
Father/Mother (4)
CL Item
Uncle/Aunt (5)
CL Item
Brother/Sister (6)
CL Item
Son/Daughter (7)
CL Item
Cousin (8)
CL Item
Cousin (2. degree) (9)
CL Item
Nephew/Niece (10)
CL Item
Grandchild (11)
Item
Side
text
C0680204 (UMLS CUI [1])
CL Item
maternal (M)
CL Item
paternal (P)
CL Item
unknown (U)
Item
Gender
text
C3172261 (UMLS CUI [1])
Code List
Gender
CL Item
Male (Male)
CL Item
Female (Female)
year of birth relative
Item
Relative - Year of birth
integer
C2826771 (UMLS CUI [1,1])
C0080103 (UMLS CUI [1,2])
screened diseases relative
Item
Screened diseases?
boolean
C0012634 (UMLS CUI [1,1])
C0018017 (UMLS CUI [1,2])
Item
Alive?
text
C3172264 (UMLS CUI [1])
Code List
Alive?
CL Item
Yes (Yes)
CL Item
No  (No )
CL Item
Unknown (Unknown)
year of death relative
Item
Relative - Year of death
integer
C0425043 (UMLS CUI [1,1])
C0439234 (UMLS CUI [1,2])
year of relative unknown
Item
Unknown
boolean
C0425043 (UMLS CUI [1,1])
C0439234 (UMLS CUI [1,2])
C0439673 (UMLS CUI [1,3])
Item Group
Family history - relatives with screened diseases
Item
Degree of affinity
integer
C0680204 (UMLS CUI [1])
Code List
Degree of affinity
CL Item
Great-Grandfather/Great-Grandmother (1)
CL Item
Grandfather/Grandmother (2)
CL Item
Granduncle/Grand-aunt (3)
CL Item
Father/Mother (4)
CL Item
Uncle/Aunt (5)
CL Item
Brother/Sister (6)
CL Item
Son/Daughter (7)
CL Item
Cousin (8)
CL Item
Cousin (2. degree) (9)
CL Item
Nephew/Niece (10)
CL Item
Grandchild (11)
Item
Side
text
C0680204 (UMLS CUI [1])
CL Item
maternal (M)
CL Item
paternal (P)
CL Item
unknown (U)
Item
Gender
text
C3172261 (UMLS CUI [1])
Code List
Gender
CL Item
Male (Male)
CL Item
Female (Female)
relative year of birth
Item
Year of birth
integer
C2826771 (UMLS CUI [1,1])
C0080103 (UMLS CUI [1,2])
Item
Diagnosis
integer
C0011900 (UMLS CUI [1])
Code List
Diagnosis
CL Item
Dementia, not further specified (1)
CL Item
Motor disturbances, not further specified (2)
CL Item
Psychiatric disease, not further specified (3)
CL Item
Subjective cognitive decline (SCD) (4)
CL Item
Amnestic mild cognitive disorder (5)
CL Item
Non-amnestic mild cognitive disorder (6)
CL Item
Probable dementia in Alzheimer's disease (AD) (7)
CL Item
Possible dementia in Alzheimer's disease (AD) (8)
CL Item
Posterior cortical atrophy (PCA) (9)
CL Item
Mixed dementia (10)
CL Item
Vascular dementia (VD) (11)
CL Item
Frototemperal dementia (FTD) - behavioral variant (12)
CL Item
Primary progressive aphasia (PPA) (13)
CL Item
Progressive nonfluent aphasia (PNFA) (14)
CL Item
Logopenic progressive Aphasia (LPA) (15)
CL Item
Semantic dementia (SemD) (16)
CL Item
bvFTD + ALS (17)
CL Item
PPA + ALS (18)
CL Item
Idiopathic Parkinson's disease (IPS) (19)
CL Item
Morbus parkinson along with MCI (PD-MCI) (20)
CL Item
Dementia due to morbus parkinson (PPD) (21)
CL Item
Dementia with Lewy bodies (DLB) (22)
CL Item
Progressive supranuclear palsy (PSP) (23)
CL Item
Corticobasal degeneration (CBD) (24)
CL Item
Multiple system atrophy (MSA) (25)
CL Item
MSA-p (Parkinson) (26)
CL Item
MSA-c (cerebral) (27)
CL Item
Essential tremor (ET) (28)
CL Item
Ataxia (29)
CL Item
Amyotrophic lateral sclerosis (ALS) (30)
CL Item
Huntington disease (HD) (31)
CL Item
Creutzfeldt-Jakob-Disease (32)
CL Item
Depression (primary disease) (33)
Item
Verified?
integer
C1711411 (UMLS CUI [1])
Code List
Verified?
CL Item
specialist (neurologist/psychiatrist) (1)
CL Item
DZNE center (2)
CL Item
no verfication (3)
age at onset of symptoms
Item
Age at onset on symptoms
integer
C0150907 (UMLS CUI [1])
register
Item
Register?
boolean
C0585825 (UMLS CUI [1])
identification
Item
Participant-ID
text
C1300638 (UMLS CUI [1])
Item Group
Handedness
Item
Which hand do you use to write a legible letter?
text
C2734042 (UMLS CUI [1])
Code List
Which hand do you use to write a legible letter?
CL Item
always left (-2) (always left (-2))
CL Item
usually left (-1) (usually left (-1))
CL Item
no preference (0) (no preference (0))
CL Item
usually right (+1) (usually right (+1))
CL Item
always right (+2) (always right (+2))
Item
Which hand do you use to throw a ball?
text
C2734034 (UMLS CUI [1])
Code List
Which hand do you use to throw a ball?
CL Item
always left (-2) (always left (-2))
CL Item
usually left (-1) (usually left (-1))
CL Item
no preference (0) (no preference (0))
CL Item
usually right (+1) (usually right (+1))
CL Item
always right (+2) (always right (+2))
Item
Which hand do you use to play with a racket in a game?
text
C2734048 (UMLS CUI [1])
Code List
Which hand do you use to play with a racket in a game?
CL Item
always left (-2) (always left (-2))
CL Item
usually left (-1) (usually left (-1))
CL Item
no preference (0) (no preference (0))
CL Item
usually right (+1) (usually right (+1))
CL Item
always right (+2) (always right (+2))
Item
Which hand do you use as upper hand using a broom?
text
C0023114 (UMLS CUI [1,1])
C3843854 (UMLS CUI [1,2])
Code List
Which hand do you use as upper hand using a broom?
CL Item
always left (-2) (always left (-2))
CL Item
usually left (-1) (usually left (-1))
CL Item
no preference (0) (no preference (0))
CL Item
usually right (+1) (usually right (+1))
CL Item
always right (+2) (always right (+2))
hand snow shoveling
Item
Which hand do you use as upper hand to use a spade snow shoveling?
text
C0023114 (UMLS CUI [1,1])
C2712668 (UMLS CUI [1,2])
Item
Which hand do you use to strike a match?
text
C2734054 (UMLS CUI [1])
Code List
Which hand do you use to strike a match?
CL Item
always left (-2) (always left (-2))
CL Item
usually left (-1) (usually left (-1))
CL Item
no preference (0) (no preference (0))
CL Item
usually right (+1) (usually right (+1))
CL Item
always right (+2) (always right (+2))
Item
Which hand do you use to hold the scissors cutting?
text
C0023114 (UMLS CUI [1,1])
C0175735 (UMLS CUI [1,2])
Code List
Which hand do you use to hold the scissors cutting?
CL Item
always left (-2) (always left (-2))
CL Item
usually left (-1) (usually left (-1))
CL Item
no preference (0) (no preference (0))
CL Item
usually right (+1) (usually right (+1))
CL Item
always right (+2) (always right (+2))
Item
Which do you use to thread a needle?
text
C2734060 (UMLS CUI [1])
Code List
Which do you use to thread a needle?
CL Item
always left (-2) (always left (-2))
CL Item
usually left (-1) (usually left (-1))
CL Item
no preference (0) (no preference (0))
CL Item
usually right (+1) (usually right (+1))
CL Item
always right (+2) (always right (+2))
Item
Which hand do you use to deal cards?
text
C2734058 (UMLS CUI [1])
Code List
Which hand do you use to deal cards?
CL Item
always left (-2) (always left (-2))
CL Item
usually left (-1) (usually left (-1))
CL Item
no preference (0) (no preference (0))
CL Item
usually right (+1) (usually right (+1))
CL Item
always right (+2) (always right (+2))
Item
Which hand do you use to hold a hammer nailing?
text
C2734052 (UMLS CUI [1])
Code List
Which hand do you use to hold a hammer nailing?
CL Item
always left (-2) (always left (-2))
CL Item
usually left (-1) (usually left (-1))
CL Item
no preference (0) (no preference (0))
CL Item
usually right (+1) (usually right (+1))
CL Item
always right (+2) (always right (+2))
Item
Which hand do you use to hold a toothbrush?
text
C2734038 (UMLS CUI [1])
Code List
Which hand do you use to hold a toothbrush?
CL Item
always left (-2) (always left (-2))
CL Item
usually left (-1) (usually left (-1))
CL Item
no preference (0) (no preference (0))
CL Item
usually right (+1) (usually right (+1))
CL Item
always right (+2) (always right (+2))
Item
Which hand do you use to open a bottle?
text
C0023114 (UMLS CUI [1,1])
C0179376 (UMLS CUI [1,2])
Code List
Which hand do you use to open a bottle?
CL Item
always left (-2) (always left (-2))
CL Item
usually left (-1) (usually left (-1))
CL Item
no preference (0) (no preference (0))
CL Item
usually right (+1) (usually right (+1))
CL Item
always right (+2) (always right (+2))
Item
Which eye do you use, if you can only use one eye (e.g. keyhole)?
text
C0422883 (UMLS CUI [1])
Code List
Which eye do you use, if you can only use one eye (e.g. keyhole)?
CL Item
left eye (left eye)
CL Item
right eye (right eye)
Item Group
Overview - Study participation
study
Item
Study abbreviation (Study number)
text
C2826693 (UMLS CUI [1])
date of consent
Item
Date of consent
date
C2985782 (UMLS CUI [1])
date end of study
Item
Date end of study
date
C2983670 (UMLS CUI [1])

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