ID

13087

Descrizione

Genetics of Rheumatoid Arthritis; ODM derived from: https://clinicaltrials.gov/show/NCT00001678

collegamento

https://clinicaltrials.gov/show/NCT00001678

Keywords

  1. 15/01/16 15/01/16 -
Titolare del copyright

CC BY-NC 3.0

Caricato su

15 gennaio 2016

DOI

Per favore, per richiedere un accesso.

Licenza

Creative Commons BY-NC 3.0

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Eligibility Rheumatoid Arthritis NCT00001678

Eligibility Rheumatoid Arthritis NCT00001678

Criteria
Descrizione

Criteria

Alias
UMLS CUI-1
C1512693
a diagnosis of rheumatoid arthritis in both sibs by the 1987 acr criteria.
Descrizione

rheumatoid arthritis

Tipo di dati

boolean

Alias
UMLS CUI [1]
C0003873
definite bony erosions in at least one affected sibling.
Descrizione

bony erosions

Tipo di dati

boolean

Alias
UMLS CUI [1]
C0587240
age of disease onset greater than 18 years and less than 60 years in at least one sibling.
Descrizione

disease onset

Tipo di dati

boolean

Alias
UMLS CUI [1]
C0277793
neither sibling has psoriasis, inflammatory bowel disease, or systemic lupus erythematosus.
Descrizione

psoriasis, inflammatory bowel disease, or systemic lupus erythematosus

Tipo di dati

boolean

Alias
UMLS CUI [1]
C0033860
UMLS CUI [2]
C0021390
UMLS CUI [3]
C0024141
blood relatives of affected sibling pairs: age greater than 18 years. where possible, all other affected siblings will be invited to participate. where possible, both parents of affected siblings will be invited to participate. other relatives, both affected and unaffected, may be invited to participate if, in the opinion of the investigators, samples from these individuals would contribute important genetic information. two cases in which this might happen are: a) extended families in which there are several affected individuals, where conventional linkage analysis might be applied; b) affected sibling pairs for which parents are unavailable, where additional siblings will provide information on parental alleles not transmitted to the affected siblings.
Descrizione

blood relatives inclusion

Tipo di dati

boolean

Alias
UMLS CUI [1]
C0001779
Exclusion Criteria
Descrizione

Exclusion Criteria

Alias
UMLS CUI-1
C0680251
psoriasis, inflammatory bowel disease, systemic lupus erythematosus.
Descrizione

psoriasis, inflammatory bowel disease, systemic lupus erythematosus.

Tipo di dati

text

Alias
UMLS CUI [1]
C0033860
UMLS CUI [2]
C0021390
UMLS CUI [3]
C0024141
inability to provide infomed consent.
Descrizione

infomed consent

Tipo di dati

text

Alias
UMLS CUI [1]
C0021430
the sole criterion for exclusion of adult blood relatives of affected sibling pairs would be inability to provide informed consent.
Descrizione

blood relatives informed consent

Tipo di dati

text

Alias
UMLS CUI [1]
C0021430

Similar models

Eligibility Rheumatoid Arthritis NCT00001678

Name
genere
Description | Question | Decode (Coded Value)
Tipo di dati
Alias
Item Group
Criteria
C1512693 (UMLS CUI-1)
rheumatoid arthritis
Item
a diagnosis of rheumatoid arthritis in both sibs by the 1987 acr criteria.
boolean
C0003873 (UMLS CUI [1])
bony erosions
Item
definite bony erosions in at least one affected sibling.
boolean
C0587240 (UMLS CUI [1])
disease onset
Item
age of disease onset greater than 18 years and less than 60 years in at least one sibling.
boolean
C0277793 (UMLS CUI [1])
psoriasis, inflammatory bowel disease, or systemic lupus erythematosus
Item
neither sibling has psoriasis, inflammatory bowel disease, or systemic lupus erythematosus.
boolean
C0033860 (UMLS CUI [1])
C0021390 (UMLS CUI [2])
C0024141 (UMLS CUI [3])
blood relatives inclusion
Item
blood relatives of affected sibling pairs: age greater than 18 years. where possible, all other affected siblings will be invited to participate. where possible, both parents of affected siblings will be invited to participate. other relatives, both affected and unaffected, may be invited to participate if, in the opinion of the investigators, samples from these individuals would contribute important genetic information. two cases in which this might happen are: a) extended families in which there are several affected individuals, where conventional linkage analysis might be applied; b) affected sibling pairs for which parents are unavailable, where additional siblings will provide information on parental alleles not transmitted to the affected siblings.
boolean
C0001779 (UMLS CUI [1])
Item Group
C0680251 (UMLS CUI-1)
psoriasis, inflammatory bowel disease, systemic lupus erythematosus.
Item
psoriasis, inflammatory bowel disease, systemic lupus erythematosus.
text
C0033860 (UMLS CUI [1])
C0021390 (UMLS CUI [2])
C0024141 (UMLS CUI [3])
infomed consent
Item
inability to provide infomed consent.
text
C0021430 (UMLS CUI [1])
blood relatives informed consent
Item
the sole criterion for exclusion of adult blood relatives of affected sibling pairs would be inability to provide informed consent.
text
C0021430 (UMLS CUI [1])

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