ID

45476

Descrição

Principal Investigator: Todd Lencz, PhD, Feinstein Institute for Medical Research, North Shore - LIJ Health System, Manhasset, NY, USA MeSH: Schizophrenia https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs000448 Schizophrenia is characterized by high heritability (~80%), yet the identification of susceptibility genes has proven extremely challenging. The Ashkenazi Jewish population, derived from a limited number of founders, may be enriched for a subset of susceptibility alleles, which may also have higher odds ratios than those detected by previous studies. GWAS was conducted in a large Ashkenazi case-control cohort, derived from the Hebrew University Genetic Resource, using the Illumina HumanOmni1-Quad BeadChip.

Link

dbGap study = phs000448

Palavras-chave

  1. 26/10/2022 26/10/2022 - Simon Heim
  2. 13/12/2022 13/12/2022 - Kristina Keller
Titular dos direitos

Todd Lencz, PhD, Feinstein Institute for Medical Research, North Shore - LIJ Health System, Manhasset, NY, USA

Transferido a

13 de dezembro de 2022

DOI

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Licença

Creative Commons BY 4.0

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dbGaP phs000448 Genetics of Schizophrenia in an Ashkenazi Jewish Case-Control Cohort

Eligibility Criteria

Inclusion and exclusion criteria
Descrição

Inclusion and exclusion criteria

Inclusion criteria for all subjects: self-identified 4 grandparents of Ashkenazi Jewish heritage Inclusion criteria for cases: hospitalized inpatients meeting DSM-IV criteria for schizophrenia or schizoaffective disorder.
Descrição

Inclusion criteria for all subjects: self-identified 4 grandparents of Ashkenazi Jewish heritage Inclusion criteria for cases: hospitalized inpatients meeting DSM-IV criteria for schizophrenia or schizoaffective disorder.

Tipo de dados

boolean

Alias
UMLS CUI [1,1]
C1512693
UMLS CUI [1,2]
C0009932
UMLS CUI [1,3]
C1706256
UMLS CUI [1,4]
C0337471
UMLS CUI [1,5]
C2135555
UMLS CUI [2,1]
C1512693
UMLS CUI [2,2]
C1706256
UMLS CUI [2,3]
C0220952
UMLS CUI [2,4]
C0036341
UMLS CUI [2,5]
C0036337

Similar models

Eligibility Criteria

Name
Tipo
Description | Question | Decode (Coded Value)
Tipo de dados
Alias
Item Group
Inclusion and exclusion criteria
Inclusion criteria for all subjects: self-identified 4 grandparents of Ashkenazi Jewish heritage Inclusion criteria for cases: hospitalized inpatients meeting DSM-IV criteria for schizophrenia or schizoaffective disorder.
Item
Inclusion criteria for all subjects: self-identified 4 grandparents of Ashkenazi Jewish heritage Inclusion criteria for cases: hospitalized inpatients meeting DSM-IV criteria for schizophrenia or schizoaffective disorder.
boolean
C1512693 (UMLS CUI [1,1])
C0009932 (UMLS CUI [1,2])
C1706256 (UMLS CUI [1,3])
C0337471 (UMLS CUI [1,4])
C2135555 (UMLS CUI [1,5])
C1512693 (UMLS CUI [2,1])
C1706256 (UMLS CUI [2,2])
C0220952 (UMLS CUI [2,3])
C0036341 (UMLS CUI [2,4])
C0036337 (UMLS CUI [2,5])

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