0 Evaluaciones

ID

42298

Descripción

Study Title: LEOSS: Lean European Open Survey on SARS-CoV-2 Infected Patients https://leoss.net Study Indication: COVID-19 Date: 19.03.2021 Published with permission by Prof. Dr. med. J.-J. Vehreschild. LEOSS, a multi-center cohort study, has been created to get more in-depth knowledge about the epidemiology and clinical course of patients infected with SARS-CoV-2. Initiated by the ESCMID Emerging Infections Task Force (EITaF) and the German Infectious Disease Society, and supported by all German Centers for Health Research (DZG), LEOSS has developed into an international network of contributors. Via an integrative research approach with anonymous recruitment and collection of routine data in an open science context, LEOSS is building a uniform clinical dataset and providing real-time analyses. For more information feel free to explore https://leoss.net/. This document is for the solid organ transplant sub-cohort. All questions refer to the day of diagnosis (diagnosis means first positive virus result). Please note that only cases with known outcome are collected at LEOSS!

Link

https://leoss.net

Palabras clave

  1. 5/11/20 5/11/20 -
  2. 24/4/21 24/4/21 -
  3. 11/5/21 11/5/21 - Sarah Riepenhausen
Titular de derechos de autor

LEOSS

Subido en

11 de mayo de 2021

DOI

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Licencia

Creative Commons BY 4.0

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    LEOSS: Lean European Open Survey on SARS-CoV-2 Infected Patients

    Solid organ transplant sub-cohort

    Type of functioning organ transplant
    Descripción

    Type of functioning organ transplant

    Alias
    UMLS CUI-1
    C0029216
    UMLS CUI-2
    C0332307
    UMLS CUI-3
    C0205245
    Heart
    Descripción

    Functional Heart transplant

    Tipo de datos

    boolean

    Alias
    UMLS CUI [1,1]
    C0018787
    UMLS CUI [1,2]
    C0029216
    UMLS CUI [1,3]
    C0205245
    Liver
    Descripción

    Functional Liver transplant

    Tipo de datos

    boolean

    Alias
    UMLS CUI [1,1]
    C0023884
    UMLS CUI [1,2]
    C0029216
    UMLS CUI [1,3]
    C0205245
    Lung
    Descripción

    Functional Lung transplant

    Tipo de datos

    boolean

    Alias
    UMLS CUI [1,1]
    C0024109
    UMLS CUI [1,2]
    C0029216
    UMLS CUI [1,3]
    C0205245
    Kidney
    Descripción

    Functional kidney transplant

    Tipo de datos

    boolean

    Alias
    UMLS CUI [1,1]
    C0022646
    UMLS CUI [1,2]
    C0029216
    UMLS CUI [1,3]
    C0205245
    Pancreas
    Descripción

    Functional pancreas transplant

    Tipo de datos

    boolean

    Alias
    UMLS CUI [1,1]
    C0030274
    UMLS CUI [1,2]
    C0029216
    UMLS CUI [1,3]
    C0205245
    Small bowel
    Descripción

    Functional small bowel transplant

    Tipo de datos

    boolean

    Alias
    UMLS CUI [1,1]
    C0021852
    UMLS CUI [1,2]
    C0029216
    UMLS CUI [1,3]
    C0205245
    Unknown
    Descripción

    Functional transplant unknown

    Tipo de datos

    boolean

    Alias
    UMLS CUI [1,1]
    C0439673
    UMLS CUI [1,2]
    C0029216
    UMLS CUI [1,3]
    C0205245
    Most recent transplantation
    Descripción

    Most recent transplantation

    Alias
    UMLS CUI-1
    C1513491
    UMLS CUI-2
    C0029216
    Time since most recent transplantation
    Descripción

    Most recent transplantation

    Tipo de datos

    integer

    Alias
    UMLS CUI [1,1]
    C1272706
    UMLS CUI [1,2]
    C1513491
    UMLS CUI [1,3]
    C0029216
    Immunsuppression at diagnosis of SARS-CoV-2
    Descripción

    Immunsuppression at diagnosis of SARS-CoV-2

    Alias
    UMLS CUI-1
    C5203676
    UMLS CUI-2
    C0021079
    UMLS CUI-3
    C0011900
    Azathioprine
    Descripción

    Indicate immunosuppressive medication at diagnosis of SARS-CoV-2.

    Tipo de datos

    integer

    Alias
    UMLS CUI [1]
    C0004482
    Belatacept
    Descripción

    Indicate immunosuppressive medication at diagnosis of SARS-CoV-2.

    Tipo de datos

    integer

    Alias
    UMLS CUI [1]
    C1619962
    Corticosteroids
    Descripción

    Indicate immunosuppressive medication at diagnosis of SARS-CoV-2.

    Tipo de datos

    integer

    Alias
    UMLS CUI [1]
    C0001617
    Cyclosporine
    Descripción

    Indicate immunosuppressive medication at diagnosis of SARS-CoV-2.

    Tipo de datos

    integer

    Alias
    UMLS CUI [1]
    C0010592
    mTOR-Inhibitor
    Descripción

    Indicate immunosuppressive medication at diagnosis of SARS-CoV-2.

    Tipo de datos

    integer

    Alias
    UMLS CUI [1]
    C2746052
    Mycophenolic acid/mycofenolate mofetil
    Descripción

    Indicate immunosuppressive medication at diagnosis of SARS-CoV-2.

    Tipo de datos

    integer

    Alias
    UMLS CUI [1]
    C0026933
    UMLS CUI [2]
    C0209368
    Tacrolimus
    Descripción

    Indicate immunosuppressive medication at diagnosis of SARS-CoV-2.

    Tipo de datos

    integer

    Alias
    UMLS CUI [1]
    C0085149
    Other
    Descripción

    Indicate other immunosuppressive medication at diagnosis of SARS-CoV-2.

    Tipo de datos

    integer

    Alias
    UMLS CUI [1,1]
    C0205394
    UMLS CUI [1,2]
    C0021079
    Graft status before COVID-19
    Descripción

    Graft status before COVID-19

    Alias
    UMLS CUI-1
    C0478647
    UMLS CUI-2
    C0332152
    UMLS CUI-3
    C5203676
    Stable graft function over >3 months
    Descripción

    Indicate graft status before diagnosis of SARS-CoV-2.

    Tipo de datos

    boolean

    Alias
    UMLS CUI [1,1]
    C0478647
    UMLS CUI [1,2]
    C0205360
    UMLS CUI [1,3]
    C0449238
    Known chronic rejection
    Descripción

    Indicate graft status before diagnosis of SARS-CoV-2.

    Tipo de datos

    boolean

    Alias
    UMLS CUI [1,1]
    C0877542
    UMLS CUI [1,2]
    C0205191
    UMLS CUI [1,3]
    C0205309
    T-cell depleting therapy within last 6 months
    Descripción

    Indicate T-cell depleting therapy within last 6 month before diagnosis of SARS-CoV-2.

    Tipo de datos

    boolean

    Alias
    UMLS CUI [1,1]
    C0677960
    UMLS CUI [1,2]
    C0332185
    B-cell depleting therapy within last 6 months
    Descripción

    Indicate B-cell depleting therapy within last 6 month before diagnosis of SARS-CoV-2.

    Tipo de datos

    boolean

    Alias
    UMLS CUI [1,1]
    C1171324
    UMLS CUI [1,2]
    C0332185
    Steroid bolus therapy within last 6 months
    Descripción

    Recent steroid bolus therapy

    Tipo de datos

    boolean

    Alias
    UMLS CUI [1,1]
    C0149783
    UMLS CUI [1,2]
    C1705509
    UMLS CUI [1,3]
    C0332185
    Unknown
    Descripción

    Graft status unknown

    Tipo de datos

    boolean

    Alias
    UMLS CUI [1,1]
    C0439673
    UMLS CUI [1,2]
    C0478647
    Therapeutic measures of transplant specific therapy
    Descripción

    Therapeutic measures of transplant specific therapy

    Alias
    UMLS CUI-1
    C0087111
    UMLS CUI-2
    C0079809
    UMLS CUI-3
    C0029216
    Azathioprine dose
    Descripción

    Indicate therapeutic measures of transplant specific therapy during SARS-CoV-2 infection.

    Tipo de datos

    integer

    Alias
    UMLS CUI [1,1]
    C0004482
    UMLS CUI [1,2]
    C3174092
    Belatacept dose
    Descripción

    Indicate therapeutic measures of transplant specific therapy during SARS-CoV-2 infection.

    Tipo de datos

    integer

    Alias
    UMLS CUI [1,1]
    C3174092
    UMLS CUI [1,2]
    C1619962
    Corticosteroid dose
    Descripción

    Indicate therapeutic measures of transplant specific therapy during SARS-CoV-2 infection.

    Tipo de datos

    integer

    Alias
    UMLS CUI [1,1]
    C0001617
    UMLS CUI [1,2]
    C3174092
    Cyclosporine dose
    Descripción

    Indicate therapeutic measures of transplant specific therapy during SARS-CoV-2 infection.

    Tipo de datos

    integer

    Alias
    UMLS CUI [1,1]
    C0010592
    UMLS CUI [1,2]
    C3174092
    mTOR-Inhibitor dose
    Descripción

    Indicate therapeutic measures of transplant specific therapy during SARS-CoV-2 infection.

    Tipo de datos

    integer

    Alias
    UMLS CUI [1,1]
    C2746052
    UMLS CUI [1,2]
    C3174092
    Mycophenolic acid/mycofenolate mofetil dose
    Descripción

    Indicate therapeutic measures of transplant specific therapy during SARS-CoV-2 infection.

    Tipo de datos

    integer

    Alias
    UMLS CUI [1,1]
    C0026933
    UMLS CUI [1,2]
    C3174092
    UMLS CUI [2,1]
    C0209368
    UMLS CUI [2,2]
    C3174092
    Tacrolimus dose
    Descripción

    Indicate therapeutic measures of transplant specific therapy during SARS-CoV-2 infection.

    Tipo de datos

    integer

    Alias
    UMLS CUI [1,1]
    C0085149
    UMLS CUI [1,2]
    C3174092
    Other
    Descripción

    Indicate other therapeutic measures of transplant specific therapy during SARS-CoV-2 infection.

    Tipo de datos

    integer

    Alias
    UMLS CUI [1,1]
    C0205394
    UMLS CUI [1,2]
    C0087111
    UMLS CUI [1,3]
    C0029216
    Is data entry for this section finished?
    Descripción

    Is data entry for this section finished?

    Alias
    UMLS CUI-1
    C4684556
    UMLS CUI-2
    C1828479
    UMLS CUI-3
    C0205197
    Is data entry for this section finished?
    Descripción

    Is data entry for this section finished?

    Tipo de datos

    integer

    Alias
    UMLS CUI [1,1]
    C4684556
    UMLS CUI [1,2]
    C1828479
    UMLS CUI [1,3]
    C0205197

    Similar models

    Solid organ transplant sub-cohort

    Name
    Tipo
    Description | Question | Decode (Coded Value)
    Tipo de datos
    Alias
    Item Group
    Type of functioning organ transplant
    C0029216 (UMLS CUI-1)
    C0332307 (UMLS CUI-2)
    C0205245 (UMLS CUI-3)
    Functional Heart transplant
    Item
    Heart
    boolean
    C0018787 (UMLS CUI [1,1])
    C0029216 (UMLS CUI [1,2])
    C0205245 (UMLS CUI [1,3])
    Functional Liver transplant
    Item
    Liver
    boolean
    C0023884 (UMLS CUI [1,1])
    C0029216 (UMLS CUI [1,2])
    C0205245 (UMLS CUI [1,3])
    Functional Lung transplant
    Item
    Lung
    boolean
    C0024109 (UMLS CUI [1,1])
    C0029216 (UMLS CUI [1,2])
    C0205245 (UMLS CUI [1,3])
    Functional kidney transplant
    Item
    Kidney
    boolean
    C0022646 (UMLS CUI [1,1])
    C0029216 (UMLS CUI [1,2])
    C0205245 (UMLS CUI [1,3])
    Functional pancreas transplant
    Item
    Pancreas
    boolean
    C0030274 (UMLS CUI [1,1])
    C0029216 (UMLS CUI [1,2])
    C0205245 (UMLS CUI [1,3])
    Functional small bowel transplant
    Item
    Small bowel
    boolean
    C0021852 (UMLS CUI [1,1])
    C0029216 (UMLS CUI [1,2])
    C0205245 (UMLS CUI [1,3])
    Functional transplant unknown
    Item
    Unknown
    boolean
    C0439673 (UMLS CUI [1,1])
    C0029216 (UMLS CUI [1,2])
    C0205245 (UMLS CUI [1,3])
    Item Group
    Most recent transplantation
    C1513491 (UMLS CUI-1)
    C0029216 (UMLS CUI-2)
    Item
    Time since most recent transplantation
    integer
    C1272706 (UMLS CUI [1,1])
    C1513491 (UMLS CUI [1,2])
    C0029216 (UMLS CUI [1,3])
    Code List
    Time since most recent transplantation
    CL Item
    <3 months (1)
    CL Item
    3 - 12 months (2)
    CL Item
    > 12 months (3)
    CL Item
    Unknown (4)
    Item Group
    Immunsuppression at diagnosis of SARS-CoV-2
    C5203676 (UMLS CUI-1)
    C0021079 (UMLS CUI-2)
    C0011900 (UMLS CUI-3)
    Item
    Azathioprine
    integer
    C0004482 (UMLS CUI [1])
    Code List
    Azathioprine
    CL Item
    Yes (1)
    CL Item
    No (2)
    CL Item
    Unknown (3)
    Item
    Belatacept
    integer
    C1619962 (UMLS CUI [1])
    Code List
    Belatacept
    CL Item
    Yes (1)
    CL Item
    No (2)
    CL Item
    Unknown (3)
    Item
    Corticosteroids
    integer
    C0001617 (UMLS CUI [1])
    Code List
    Corticosteroids
    CL Item
    Yes (1)
    CL Item
    No (2)
    CL Item
    Unknown (3)
    Item
    Cyclosporine
    integer
    C0010592 (UMLS CUI [1])
    Code List
    Cyclosporine
    CL Item
    Yes (1)
    CL Item
    No (2)
    CL Item
    Unknown (3)
    Item
    mTOR-Inhibitor
    integer
    C2746052 (UMLS CUI [1])
    Code List
    mTOR-Inhibitor
    CL Item
    Yes (1)
    CL Item
    No (2)
    CL Item
    Unknown (3)
    Item
    Mycophenolic acid/mycofenolate mofetil
    integer
    C0026933 (UMLS CUI [1])
    C0209368 (UMLS CUI [2])
    Code List
    Mycophenolic acid/mycofenolate mofetil
    CL Item
    Yes (1)
    CL Item
    No (2)
    CL Item
    Unknown (3)
    Item
    Tacrolimus
    integer
    C0085149 (UMLS CUI [1])
    Code List
    Tacrolimus
    CL Item
    Yes (1)
    CL Item
    No (2)
    CL Item
    Unknown (3)
    Item
    Other
    integer
    C0205394 (UMLS CUI [1,1])
    C0021079 (UMLS CUI [1,2])
    Code List
    Other
    CL Item
    Yes (1)
    CL Item
    No (2)
    CL Item
    Unknown (3)
    Item Group
    Graft status before COVID-19
    C0478647 (UMLS CUI-1)
    C0332152 (UMLS CUI-2)
    C5203676 (UMLS CUI-3)
    Stable graft function over 3 months
    Item
    Stable graft function over >3 months
    boolean
    C0478647 (UMLS CUI [1,1])
    C0205360 (UMLS CUI [1,2])
    C0449238 (UMLS CUI [1,3])
    Known chronic rejection
    Item
    Known chronic rejection
    boolean
    C0877542 (UMLS CUI [1,1])
    C0205191 (UMLS CUI [1,2])
    C0205309 (UMLS CUI [1,3])
    Recent T-cell depletion
    Item
    T-cell depleting therapy within last 6 months
    boolean
    C0677960 (UMLS CUI [1,1])
    C0332185 (UMLS CUI [1,2])
    Recent B-cell depletion
    Item
    B-cell depleting therapy within last 6 months
    boolean
    C1171324 (UMLS CUI [1,1])
    C0332185 (UMLS CUI [1,2])
    Recent steroid bolus therapy
    Item
    Steroid bolus therapy within last 6 months
    boolean
    C0149783 (UMLS CUI [1,1])
    C1705509 (UMLS CUI [1,2])
    C0332185 (UMLS CUI [1,3])
    Graft status unknown
    Item
    Unknown
    boolean
    C0439673 (UMLS CUI [1,1])
    C0478647 (UMLS CUI [1,2])
    Item Group
    Therapeutic measures of transplant specific therapy
    C0087111 (UMLS CUI-1)
    C0079809 (UMLS CUI-2)
    C0029216 (UMLS CUI-3)
    Item
    Azathioprine dose
    integer
    C0004482 (UMLS CUI [1,1])
    C3174092 (UMLS CUI [1,2])
    Code List
    Azathioprine dose
    CL Item
    Unchanged (1)
    CL Item
    >= 50% reduction (2)
    CL Item
    Stopp (3)
    CL Item
    Unknown (4)
    Item
    Belatacept dose
    integer
    C3174092 (UMLS CUI [1,1])
    C1619962 (UMLS CUI [1,2])
    Code List
    Belatacept dose
    CL Item
    Unchanged (1)
    CL Item
    >= 50% reduction (2)
    CL Item
    Stopp (3)
    CL Item
    Unknown (4)
    Item
    Corticosteroid dose
    integer
    C0001617 (UMLS CUI [1,1])
    C3174092 (UMLS CUI [1,2])
    Code List
    Corticosteroid dose
    CL Item
    Unchanged (1)
    CL Item
    >= 50% reduction (2)
    CL Item
    Stopp (3)
    CL Item
    Unknown (4)
    Item
    Cyclosporine dose
    integer
    C0010592 (UMLS CUI [1,1])
    C3174092 (UMLS CUI [1,2])
    Code List
    Cyclosporine dose
    CL Item
    Unchanged (1)
    CL Item
    >= 50% reduction (2)
    CL Item
    Stopp (3)
    CL Item
    Unknown (4)
    Item
    mTOR-Inhibitor dose
    integer
    C2746052 (UMLS CUI [1,1])
    C3174092 (UMLS CUI [1,2])
    Code List
    mTOR-Inhibitor dose
    CL Item
    Unchanged (1)
    CL Item
    >= 50% reduction (2)
    CL Item
    Stopp (3)
    CL Item
    Unknown (4)
    Item
    Mycophenolic acid/mycofenolate mofetil dose
    integer
    C0026933 (UMLS CUI [1,1])
    C3174092 (UMLS CUI [1,2])
    C0209368 (UMLS CUI [2,1])
    C3174092 (UMLS CUI [2,2])
    Code List
    Mycophenolic acid/mycofenolate mofetil dose
    CL Item
    Unchanged (1)
    CL Item
    >= 50% reduction (2)
    CL Item
    Stopp (3)
    CL Item
    Unknown (4)
    Item
    Tacrolimus dose
    integer
    C0085149 (UMLS CUI [1,1])
    C3174092 (UMLS CUI [1,2])
    Code List
    Tacrolimus dose
    CL Item
    Unchanged (1)
    CL Item
    >= 50% reduction (2)
    CL Item
    Stopp (3)
    CL Item
    Unknown (4)
    Item
    Other
    integer
    C0205394 (UMLS CUI [1,1])
    C0087111 (UMLS CUI [1,2])
    C0029216 (UMLS CUI [1,3])
    Code List
    Other
    CL Item
    Unchanged (1)
    CL Item
    >= 50% reduction (2)
    CL Item
    Stopp (3)
    CL Item
    Unknown (4)
    Item Group
    Is data entry for this section finished?
    C4684556 (UMLS CUI-1)
    C1828479 (UMLS CUI-2)
    C0205197 (UMLS CUI-3)
    Item
    Is data entry for this section finished?
    integer
    C4684556 (UMLS CUI [1,1])
    C1828479 (UMLS CUI [1,2])
    C0205197 (UMLS CUI [1,3])
    Code List
    Is data entry for this section finished?
    CL Item
    Yes (1)
    CL Item
    No (2)

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