ID

42298

Description

Study Title: LEOSS: Lean European Open Survey on SARS-CoV-2 Infected Patients https://leoss.net Study Indication: COVID-19 Date: 19.03.2021 Published with permission by Prof. Dr. med. J.-J. Vehreschild. LEOSS, a multi-center cohort study, has been created to get more in-depth knowledge about the epidemiology and clinical course of patients infected with SARS-CoV-2. Initiated by the ESCMID Emerging Infections Task Force (EITaF) and the German Infectious Disease Society, and supported by all German Centers for Health Research (DZG), LEOSS has developed into an international network of contributors. Via an integrative research approach with anonymous recruitment and collection of routine data in an open science context, LEOSS is building a uniform clinical dataset and providing real-time analyses. For more information feel free to explore https://leoss.net/. This document is for the solid organ transplant sub-cohort. All questions refer to the day of diagnosis (diagnosis means first positive virus result). Please note that only cases with known outcome are collected at LEOSS!

Link

https://leoss.net

Keywords

Versions (3)
  1. 11/5/20 11/5/20 -
  2. 4/24/21 4/24/21 -
  3. 5/11/21 5/11/21 - Sarah Riepenhausen
Copyright Holder

LEOSS

Uploaded on

May 11, 2021

DOI

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License

Creative Commons BY 4.0
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LEOSS: Lean European Open Survey on SARS-CoV-2 Infected Patients

English

Solid organ transplant sub-cohort

1 forms  
Type of functioning organ transplant
Description

Type of functioning organ transplant

Alias
UMLS CUI-1
C0029216
UMLS CUI-2
C0332307
UMLS CUI-3
C0205245
Heart
Description

Functional Heart transplant

Data type

boolean

Alias
UMLS CUI [1,1]
C0018787
UMLS CUI [1,2]
C0029216
UMLS CUI [1,3]
C0205245
Liver
Description

Functional Liver transplant

Data type

boolean

Alias
UMLS CUI [1,1]
C0023884
UMLS CUI [1,2]
C0029216
UMLS CUI [1,3]
C0205245
Lung
Description

Functional Lung transplant

Data type

boolean

Alias
UMLS CUI [1,1]
C0024109
UMLS CUI [1,2]
C0029216
UMLS CUI [1,3]
C0205245
Kidney
Description

Functional kidney transplant

Data type

boolean

Alias
UMLS CUI [1,1]
C0022646
UMLS CUI [1,2]
C0029216
UMLS CUI [1,3]
C0205245
Pancreas
Description

Functional pancreas transplant

Data type

boolean

Alias
UMLS CUI [1,1]
C0030274
UMLS CUI [1,2]
C0029216
UMLS CUI [1,3]
C0205245
Small bowel
Description

Functional small bowel transplant

Data type

boolean

Alias
UMLS CUI [1,1]
C0021852
UMLS CUI [1,2]
C0029216
UMLS CUI [1,3]
C0205245
Unknown
Description

Functional transplant unknown

Data type

boolean

Alias
UMLS CUI [1,1]
C0439673
UMLS CUI [1,2]
C0029216
UMLS CUI [1,3]
C0205245
Most recent transplantation
Description

Most recent transplantation

Alias
UMLS CUI-1
C1513491
UMLS CUI-2
C0029216
Time since most recent transplantation
Description

Most recent transplantation

Data type

integer

Alias
UMLS CUI [1,1]
C1272706
UMLS CUI [1,2]
C1513491
UMLS CUI [1,3]
C0029216
Immunsuppression at diagnosis of SARS-CoV-2
Description

Immunsuppression at diagnosis of SARS-CoV-2

Alias
UMLS CUI-1
C5203676
UMLS CUI-2
C0021079
UMLS CUI-3
C0011900
Azathioprine
Description

Indicate immunosuppressive medication at diagnosis of SARS-CoV-2.

Data type

integer

Alias
UMLS CUI [1]
C0004482
Belatacept
Description

Indicate immunosuppressive medication at diagnosis of SARS-CoV-2.

Data type

integer

Alias
UMLS CUI [1]
C1619962
Corticosteroids
Description

Indicate immunosuppressive medication at diagnosis of SARS-CoV-2.

Data type

integer

Alias
UMLS CUI [1]
C0001617
Cyclosporine
Description

Indicate immunosuppressive medication at diagnosis of SARS-CoV-2.

Data type

integer

Alias
UMLS CUI [1]
C0010592
mTOR-Inhibitor
Description

Indicate immunosuppressive medication at diagnosis of SARS-CoV-2.

Data type

integer

Alias
UMLS CUI [1]
C2746052
Mycophenolic acid/mycofenolate mofetil
Description

Indicate immunosuppressive medication at diagnosis of SARS-CoV-2.

Data type

integer

Alias
UMLS CUI [1]
C0026933
UMLS CUI [2]
C0209368
Tacrolimus
Description

Indicate immunosuppressive medication at diagnosis of SARS-CoV-2.

Data type

integer

Alias
UMLS CUI [1]
C0085149
Other
Description

Indicate other immunosuppressive medication at diagnosis of SARS-CoV-2.

Data type

integer

Alias
UMLS CUI [1,1]
C0205394
UMLS CUI [1,2]
C0021079
Graft status before COVID-19
Description

Graft status before COVID-19

Alias
UMLS CUI-1
C0478647
UMLS CUI-2
C0332152
UMLS CUI-3
C5203676
Stable graft function over >3 months
Description

Indicate graft status before diagnosis of SARS-CoV-2.

Data type

boolean

Alias
UMLS CUI [1,1]
C0478647
UMLS CUI [1,2]
C0205360
UMLS CUI [1,3]
C0449238
Known chronic rejection
Description

Indicate graft status before diagnosis of SARS-CoV-2.

Data type

boolean

Alias
UMLS CUI [1,1]
C0877542
UMLS CUI [1,2]
C0205191
UMLS CUI [1,3]
C0205309
T-cell depleting therapy within last 6 months
Description

Indicate T-cell depleting therapy within last 6 month before diagnosis of SARS-CoV-2.

Data type

boolean

Alias
UMLS CUI [1,1]
C0677960
UMLS CUI [1,2]
C0332185
B-cell depleting therapy within last 6 months
Description

Indicate B-cell depleting therapy within last 6 month before diagnosis of SARS-CoV-2.

Data type

boolean

Alias
UMLS CUI [1,1]
C1171324
UMLS CUI [1,2]
C0332185
Steroid bolus therapy within last 6 months
Description

Recent steroid bolus therapy

Data type

boolean

Alias
UMLS CUI [1,1]
C0149783
UMLS CUI [1,2]
C1705509
UMLS CUI [1,3]
C0332185
Unknown
Description

Graft status unknown

Data type

boolean

Alias
UMLS CUI [1,1]
C0439673
UMLS CUI [1,2]
C0478647
Therapeutic measures of transplant specific therapy
Description

Therapeutic measures of transplant specific therapy

Alias
UMLS CUI-1
C0087111
UMLS CUI-2
C0079809
UMLS CUI-3
C0029216
Azathioprine dose
Description

Indicate therapeutic measures of transplant specific therapy during SARS-CoV-2 infection.

Data type

integer

Alias
UMLS CUI [1,1]
C0004482
UMLS CUI [1,2]
C3174092
Belatacept dose
Description

Indicate therapeutic measures of transplant specific therapy during SARS-CoV-2 infection.

Data type

integer

Alias
UMLS CUI [1,1]
C3174092
UMLS CUI [1,2]
C1619962
Corticosteroid dose
Description

Indicate therapeutic measures of transplant specific therapy during SARS-CoV-2 infection.

Data type

integer

Alias
UMLS CUI [1,1]
C0001617
UMLS CUI [1,2]
C3174092
Cyclosporine dose
Description

Indicate therapeutic measures of transplant specific therapy during SARS-CoV-2 infection.

Data type

integer

Alias
UMLS CUI [1,1]
C0010592
UMLS CUI [1,2]
C3174092
mTOR-Inhibitor dose
Description

Indicate therapeutic measures of transplant specific therapy during SARS-CoV-2 infection.

Data type

integer

Alias
UMLS CUI [1,1]
C2746052
UMLS CUI [1,2]
C3174092
Mycophenolic acid/mycofenolate mofetil dose
Description

Indicate therapeutic measures of transplant specific therapy during SARS-CoV-2 infection.

Data type

integer

Alias
UMLS CUI [1,1]
C0026933
UMLS CUI [1,2]
C3174092
UMLS CUI [2,1]
C0209368
UMLS CUI [2,2]
C3174092
Tacrolimus dose
Description

Indicate therapeutic measures of transplant specific therapy during SARS-CoV-2 infection.

Data type

integer

Alias
UMLS CUI [1,1]
C0085149
UMLS CUI [1,2]
C3174092
Other
Description

Indicate other therapeutic measures of transplant specific therapy during SARS-CoV-2 infection.

Data type

integer

Alias
UMLS CUI [1,1]
C0205394
UMLS CUI [1,2]
C0087111
UMLS CUI [1,3]
C0029216
Is data entry for this section finished?
Description

Is data entry for this section finished?

Alias
UMLS CUI-1
C4684556
UMLS CUI-2
C1828479
UMLS CUI-3
C0205197
Is data entry for this section finished?
Description

Is data entry for this section finished?

Data type

integer

Alias
UMLS CUI [1,1]
C4684556
UMLS CUI [1,2]
C1828479
UMLS CUI [1,3]
C0205197
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Similar models

Solid organ transplant sub-cohort

1 forms
Name
Type
Description | Question | Decode (Coded Value)
Data type
Alias
Item Group
Type of functioning organ transplant
C0029216 (UMLS CUI-1)
C0332307 (UMLS CUI-2)
C0205245 (UMLS CUI-3)
Functional Heart transplant
Item
Heart
boolean
C0018787 (UMLS CUI [1,1])
C0029216 (UMLS CUI [1,2])
C0205245 (UMLS CUI [1,3])
Functional Liver transplant
Item
Liver
boolean
C0023884 (UMLS CUI [1,1])
C0029216 (UMLS CUI [1,2])
C0205245 (UMLS CUI [1,3])
Functional Lung transplant
Item
Lung
boolean
C0024109 (UMLS CUI [1,1])
C0029216 (UMLS CUI [1,2])
C0205245 (UMLS CUI [1,3])
Functional kidney transplant
Item
Kidney
boolean
C0022646 (UMLS CUI [1,1])
C0029216 (UMLS CUI [1,2])
C0205245 (UMLS CUI [1,3])
Functional pancreas transplant
Item
Pancreas
boolean
C0030274 (UMLS CUI [1,1])
C0029216 (UMLS CUI [1,2])
C0205245 (UMLS CUI [1,3])
Functional small bowel transplant
Item
Small bowel
boolean
C0021852 (UMLS CUI [1,1])
C0029216 (UMLS CUI [1,2])
C0205245 (UMLS CUI [1,3])
Functional transplant unknown
Item
Unknown
boolean
C0439673 (UMLS CUI [1,1])
C0029216 (UMLS CUI [1,2])
C0205245 (UMLS CUI [1,3])
Item Group
Most recent transplantation
C1513491 (UMLS CUI-1)
C0029216 (UMLS CUI-2)
Item
Time since most recent transplantation
integer
C1272706 (UMLS CUI [1,1])
C1513491 (UMLS CUI [1,2])
C0029216 (UMLS CUI [1,3])
TX_recent
Code List
Time since most recent transplantation
CL Item
<3 months (1)
CL Item
3 - 12 months (2)
CL Item
> 12 months (3)
CL Item
Unknown (4)
Item Group
Immunsuppression at diagnosis of SARS-CoV-2
C5203676 (UMLS CUI-1)
C0021079 (UMLS CUI-2)
C0011900 (UMLS CUI-3)
Item
Azathioprine
integer
C0004482 (UMLS CUI [1])
Azathioprine
Code List
Azathioprine
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Belatacept
integer
C1619962 (UMLS CUI [1])
Belatacept
Code List
Belatacept
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Corticosteroids
integer
C0001617 (UMLS CUI [1])
Corticosteroids
Code List
Corticosteroids
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Cyclosporine
integer
C0010592 (UMLS CUI [1])
Cyclosporine
Code List
Cyclosporine
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
mTOR-Inhibitor
integer
C2746052 (UMLS CUI [1])
mTOR-Inhibitor
Code List
mTOR-Inhibitor
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Mycophenolic acid/mycofenolate mofetil
integer
C0026933 (UMLS CUI [1])
C0209368 (UMLS CUI [2])
Mycophenolic acid/mycofenolate mofetil
Code List
Mycophenolic acid/mycofenolate mofetil
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Tacrolimus
integer
C0085149 (UMLS CUI [1])
Tacrolimus
Code List
Tacrolimus
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Other
integer
C0205394 (UMLS CUI [1,1])
C0021079 (UMLS CUI [1,2])
Unknown
Code List
Other
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item Group
Graft status before COVID-19
C0478647 (UMLS CUI-1)
C0332152 (UMLS CUI-2)
C5203676 (UMLS CUI-3)
Stable graft function over 3 months
Item
Stable graft function over >3 months
boolean
C0478647 (UMLS CUI [1,1])
C0205360 (UMLS CUI [1,2])
C0449238 (UMLS CUI [1,3])
Known chronic rejection
Item
Known chronic rejection
boolean
C0877542 (UMLS CUI [1,1])
C0205191 (UMLS CUI [1,2])
C0205309 (UMLS CUI [1,3])
Recent T-cell depletion
Item
T-cell depleting therapy within last 6 months
boolean
C0677960 (UMLS CUI [1,1])
C0332185 (UMLS CUI [1,2])
Recent B-cell depletion
Item
B-cell depleting therapy within last 6 months
boolean
C1171324 (UMLS CUI [1,1])
C0332185 (UMLS CUI [1,2])
Recent steroid bolus therapy
Item
Steroid bolus therapy within last 6 months
boolean
C0149783 (UMLS CUI [1,1])
C1705509 (UMLS CUI [1,2])
C0332185 (UMLS CUI [1,3])
Graft status unknown
Item
Unknown
boolean
C0439673 (UMLS CUI [1,1])
C0478647 (UMLS CUI [1,2])
Item Group
Therapeutic measures of transplant specific therapy
C0087111 (UMLS CUI-1)
C0079809 (UMLS CUI-2)
C0029216 (UMLS CUI-3)
Item
Azathioprine dose
integer
C0004482 (UMLS CUI [1,1])
C3174092 (UMLS CUI [1,2])
Azathioprine dose
Code List
Azathioprine dose
CL Item
Unchanged (1)
CL Item
>= 50% reduction (2)
CL Item
Stopp (3)
CL Item
Unknown (4)
Item
Belatacept dose
integer
C3174092 (UMLS CUI [1,1])
C1619962 (UMLS CUI [1,2])
Belatacept dose
Code List
Belatacept dose
CL Item
Unchanged (1)
CL Item
>= 50% reduction (2)
CL Item
Stopp (3)
CL Item
Unknown (4)
Item
Corticosteroid dose
integer
C0001617 (UMLS CUI [1,1])
C3174092 (UMLS CUI [1,2])
Corticosteroid dose
Code List
Corticosteroid dose
CL Item
Unchanged (1)
CL Item
>= 50% reduction (2)
CL Item
Stopp (3)
CL Item
Unknown (4)
Item
Cyclosporine dose
integer
C0010592 (UMLS CUI [1,1])
C3174092 (UMLS CUI [1,2])
Cyclosporine dose
Code List
Cyclosporine dose
CL Item
Unchanged (1)
CL Item
>= 50% reduction (2)
CL Item
Stopp (3)
CL Item
Unknown (4)
Item
mTOR-Inhibitor dose
integer
C2746052 (UMLS CUI [1,1])
C3174092 (UMLS CUI [1,2])
mTOR-Inhibitor dose
Code List
mTOR-Inhibitor dose
CL Item
Unchanged (1)
CL Item
>= 50% reduction (2)
CL Item
Stopp (3)
CL Item
Unknown (4)
Item
Mycophenolic acid/mycofenolate mofetil dose
integer
C0026933 (UMLS CUI [1,1])
C3174092 (UMLS CUI [1,2])
C0209368 (UMLS CUI [2,1])
C3174092 (UMLS CUI [2,2])
Mycophenolic acid/mycofenolate mofetil dose
Code List
Mycophenolic acid/mycofenolate mofetil dose
CL Item
Unchanged (1)
CL Item
>= 50% reduction (2)
CL Item
Stopp (3)
CL Item
Unknown (4)
Item
Tacrolimus dose
integer
C0085149 (UMLS CUI [1,1])
C3174092 (UMLS CUI [1,2])
Tacrolimus dose
Code List
Tacrolimus dose
CL Item
Unchanged (1)
CL Item
>= 50% reduction (2)
CL Item
Stopp (3)
CL Item
Unknown (4)
Item
Other
integer
C0205394 (UMLS CUI [1,1])
C0087111 (UMLS CUI [1,2])
C0029216 (UMLS CUI [1,3])
Other
Code List
Other
CL Item
Unchanged (1)
CL Item
>= 50% reduction (2)
CL Item
Stopp (3)
CL Item
Unknown (4)
Item Group
Is data entry for this section finished?
C4684556 (UMLS CUI-1)
C1828479 (UMLS CUI-2)
C0205197 (UMLS CUI-3)
Item
Is data entry for this section finished?
integer
C4684556 (UMLS CUI [1,1])
C1828479 (UMLS CUI [1,2])
C0205197 (UMLS CUI [1,3])
BL_Completed
Code List
Is data entry for this section finished?
CL Item
Yes (1)
CL Item
No (2)
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