ID

41517

Description

Study Title: LEOSS: Lean European Open Survey on SARS-CoV-2 Infected Patients https://leoss.net Study Indication: COVID-19 Date: 14.10.2020, 15:22 Published with permission by Prof. Dr. med. J.-J. Vehreschild. LEOSS is mandated by the ESCMID Emerging Infections Task Force (EITaF) and supported by the German Infectious Disease Society. It aims at a better understanding of the implications of the new virus on patients by systematically documenting patient data across Europe (Text adapted from leoss.net). For more information please visit the official website. This document is for Immunsuppressive drug-related data. If a text field can't be filled out, note 'ND' (for not determined).

Link

https://leoss.net

Keywords

Versions (2)
  1. 10/30/20 10/30/20 -
  2. 5/7/21 5/7/21 -
Copyright Holder

LEOSS

Uploaded on

October 30, 2020

DOI

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License

Creative Commons BY 4.0
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LEOSS: Lean European Open Survey on SARS-CoV-2 Infected Patients

English

Immunsuppressive drug-related data

1 forms  
Antibodies: Anti-CD20
Description

Antibodies: Anti-CD20

Alias
UMLS CUI-1
C3891557
Obinutuzumab (in the last 6 months)
Description

Note: This question is critical for the further course of the questionnaire.

Data type

integer

Alias
UMLS CUI [1,1]
C2742503
UMLS CUI [1,2]
C0332185
Ocrelizumab (in the last 6 months)
Description

Note: This question is critical for the further course of the questionnaire.

Data type

integer

Alias
UMLS CUI [1,1]
C1882138
UMLS CUI [1,2]
C0332185
Ofatumumab (in the last 3 months)
Description

Note: This question is critical for the further course of the questionnaire.

Data type

integer

Alias
UMLS CUI [1,1]
C1832027
UMLS CUI [1,2]
C0332185
Rituximab (in the last 6 months)
Description

Note: This question is critical for the further course of the questionnaire.

Data type

integer

Alias
UMLS CUI [1,1]
C0393022
UMLS CUI [1,2]
C0332185
Antibodies: CD-22
Description

Antibodies: CD-22

Alias
UMLS CUI-1
C0003241
UMLS CUI-2
C0054947
Inotuzumab-Ozogamicin
Description

Note: This question is critical for the further course of the questionnaire.

Data type

integer

Alias
UMLS CUI [1]
C1567130
Antibodies: CD-38
Description

Antibodies: CD-38

Alias
UMLS CUI-1
C0003241
UMLS CUI-2
C0075742
Daratumumab
Description

Note: This question is critical for the further course of the questionnaire.

Data type

integer

Alias
UMLS CUI [1]
C2346801
Antibodies: CD-52
Description

Antibodies: CD-52

Alias
UMLS CUI-1
C0003241
UMLS CUI-2
C1610534
Alemtuzumab (in the last 12 months)
Description

Note: This question is critical for the further course of the questionnaire.

Data type

integer

Alias
UMLS CUI [1,1]
C0383429
UMLS CUI [1,2]
C0332185
Antibodies: Anti-CD79b
Description

Antibodies: Anti-CD79b

Alias
UMLS CUI-1
C0104979
UMLS CUI-2
C0003241
Polatuzumab-Vedotin
Description

Note: This question is critical for the further course of the questionnaire.

Data type

integer

Alias
UMLS CUI [1]
C4078806
Antibodies: B Lymphocyte stimulator-specific inhibitor (BLyS)
Description

Antibodies: B Lymphocyte stimulator-specific inhibitor (BLyS)

Alias
UMLS CUI-1
C0003241
UMLS CUI-2
C3160093
Belimumab (in the last 6 months)
Description

Note: This question is critical for the further course of the questionnaire.

Data type

integer

Alias
UMLS CUI [1,1]
C1723401
UMLS CUI [1,2]
C0332185
Antibodies: CD19-BiTE
Description

Antibodies: CD19-BiTE

Alias
UMLS CUI-1
C0003241
UMLS CUI-2
C4727095
Blinatumomab
Description

Note: This question is critical for the further course of the questionnaire.

Data type

integer

Alias
UMLS CUI [1]
C3853839
Antibodies: Complement inhibitors
Description

Antibodies: Complement inhibitors

Alias
UMLS CUI-1
C0003241
UMLS CUI-2
C1564892
Crovalimab
Description

Note: This question is critical for the further course of the questionnaire.

Data type

integer

Alias
UMLS CUI [1,1]
C1564892
UMLS CUI [1,2]
C3846158
Eculizumab
Description

Note: This question is critical for the further course of the questionnaire.

Data type

integer

Alias
UMLS CUI [1]
C1541483
Pegcetacoplan (APL-2)
Description

Note: This question is critical for the further course of the questionnaire.

Data type

integer

Alias
UMLS CUI [1]
C4053680
Ravulizumab
Description

Note: This question is critical for the further course of the questionnaire.

Data type

integer

Alias
UMLS CUI [1]
C4550350
Antibodies: Co-stimulation inhibitors
Description

Antibodies: Co-stimulation inhibitors

Alias
UMLS CUI-1
C0003241
UMLS CUI-2
C1622572
UMLS CUI-3
C1999216
Abatacept
Description

Note: This question is critical for the further course of the questionnaire.

Data type

integer

Alias
UMLS CUI [1]
C1619966
Belatacept
Description

Note: This question is critical for the further course of the questionnaire.

Data type

integer

Alias
UMLS CUI [1]
C1619962
Antibodies: Integrin antagonists
Description

Antibodies: Integrin antagonists

Alias
UMLS CUI-1
C0003241
UMLS CUI-2
C2917367
Natalizumab
Description

Note: This question is critical for the further course of the questionnaire.

Data type

integer

Alias
UMLS CUI [1]
C1172734
Vedolizumab
Description

Note: This question is critical for the further course of the questionnaire.

Data type

integer

Alias
UMLS CUI [1]
C2742797
Antibodies: Interleukin inhibitors
Description

Antibodies: Interleukin inhibitors

Alias
UMLS CUI-1
C3653320
UMLS CUI-2
C0003241
Basiliximab
Description

Note: This question is critical for the further course of the questionnaire.

Data type

integer

Alias
UMLS CUI [1]
C0676831
Canakinumab
Description

Note: This question is critical for the further course of the questionnaire.

Data type

integer

Alias
UMLS CUI [1]
C2718773
Ixekizumab
Description

Note: This question is critical for the further course of the questionnaire.

Data type

integer

Alias
UMLS CUI [1]
C3489764
Sarilumab
Description

Note: This question is critical for the further course of the questionnaire.

Data type

integer

Alias
UMLS CUI [1]
C3885145
Secukinumab
Description

Note: This question is critical for the further course of the questionnaire.

Data type

integer

Alias
UMLS CUI [1]
C3179547
Tocilizumab
Description

Note: This question is critical for the further course of the questionnaire.

Data type

integer

Alias
UMLS CUI [1]
C1609165
Ustekinumab
Description

Note: This question is critical for the further course of the questionnaire.

Data type

integer

Alias
UMLS CUI [1]
C1608841
Antibodies: TNF-alpha inhibitors
Description

Antibodies: TNF-alpha inhibitors

Alias
UMLS CUI-1
C3653350
UMLS CUI-2
C0003241
Adalimumab
Description

Note: This question is critical for the further course of the questionnaire.

Data type

integer

Alias
UMLS CUI [1]
C1122087
Certolizumab
Description

Note: This question is critical for the further course of the questionnaire.

Data type

integer

Alias
UMLS CUI [1]
C1872109
Etanercept
Description

Note: This question is critical for the further course of the questionnaire.

Data type

integer

Alias
UMLS CUI [1]
C0717758
Golimumab
Description

Note: This question is critical for the further course of the questionnaire.

Data type

integer

Alias
UMLS CUI [1]
C2353893
Infliximab
Description

Note: This question is critical for the further course of the questionnaire.

Data type

integer

Alias
UMLS CUI [1]
C0666743
Other Antibodies
Description

Other Antibodies

Alias
UMLS CUI-1
C0003241
UMLS CUI-2
C0205394
Other Antibodies
Description

Note: This question is critical for the further course of the questionnaire.

Data type

integer

Alias
UMLS CUI [1,1]
C0003241
UMLS CUI [1,2]
C0205394
Other, please specify:
Description

Other Antibodies, to specify

Data type

text

Alias
UMLS CUI [1,1]
C0205394
UMLS CUI [1,2]
C1521902
UMLS CUI [1,3]
C0003241
Chemotherapeutics: Antimetabolites
Description

Chemotherapeutics: Antimetabolites

Alias
UMLS CUI-1
C0003376
UMLS CUI-2
C0729502
6-Mercaptopurine
Description

Note: This question is critical for the further course of the questionnaire.

Data type

integer

Alias
UMLS CUI [1]
C0000618
Azathioprine
Description

Note: This question is critical for the further course of the questionnaire.

Data type

integer

Alias
UMLS CUI [1]
C0004482
Leflunomide
Description

Note: This question is critical for the further course of the questionnaire.

Data type

integer

Alias
UMLS CUI [1]
C0063041
Methotrexate
Description

Note: This question is critical for the further course of the questionnaire.

Data type

integer

Alias
UMLS CUI [1]
C0025677
Mycophenolate mofetil / Mycophenolic acid
Description

Note: This question is critical for the further course of the questionnaire.

Data type

integer

Alias
UMLS CUI [1]
C0209368
UMLS CUI [2]
C0026933
Sulfasalazine
Description

Note: This question is critical for the further course of the questionnaire.

Data type

integer

Alias
UMLS CUI [1]
C0036078
Teriflunomide
Description

Note: This question is critical for the further course of the questionnaire.

Data type

integer

Alias
UMLS CUI [1]
C1718383
Chemotherapeutics: Cytostatics
Description

Chemotherapeutics: Cytostatics

Alias
UMLS CUI-1
C0010858
UMLS CUI-2
C0729502
Cladribine (2-CDA) i.v./s.c. (in the last 12 months)
Description

Note: This question is critical for the further course of the questionnaire.

Data type

integer

Alias
UMLS CUI [1,1]
C0092801
UMLS CUI [1,2]
C0348016
UMLS CUI [1,3]
C0332185
UMLS CUI [2,1]
C0092801
UMLS CUI [2,2]
C0021499
UMLS CUI [2,3]
C0332185
Cladribine (2-CDA) p.o. (in the last 12 months)
Description

Note: This question is critical for the further course of the questionnaire.

Data type

integer

Alias
UMLS CUI [1,1]
C0092801
UMLS CUI [1,2]
C0001563
UMLS CUI [1,3]
C0332185
Cyclophosphamide i.v.(in the last 3 months)
Description

Note: This question is critical for the further course of the questionnaire.

Data type

integer

Alias
UMLS CUI [1,1]
C0010583
UMLS CUI [1,2]
C0348016
UMLS CUI [1,3]
C0332185
Cyclophosphamide p.o. (in the last 3 months)
Description

Note: This question is critical for the further course of the questionnaire.

Data type

integer

Alias
UMLS CUI [1,1]
C0010583
UMLS CUI [1,2]
C0001563
UMLS CUI [1,3]
C0332185
Mitoxantrone (in the last 3 months)
Description

Note: This question is critical for the further course of the questionnaire.

Data type

integer

Alias
UMLS CUI [1,1]
C0026259
UMLS CUI [1,2]
C0332185
Other Chemotherapeutics
Description

Other Chemotherapeutics

Alias
UMLS CUI-1
C0205394
UMLS CUI-2
C0729502
Other Chemotherapeutics
Description

Note: This question is critical for the further course of the questionnaire.

Data type

integer

Alias
UMLS CUI [1,1]
C0205394
UMLS CUI [1,2]
C0729502
Other, please specify:
Description

Note: This question is critical for the further course of the questionnaire.

Data type

text

Alias
UMLS CUI [1,1]
C0729502
UMLS CUI [1,2]
C0205394
UMLS CUI [1,3]
C1521902
Inhibitors: Calcineurin inhibitors
Description

Inhibitors: Calcineurin inhibitors

Alias
UMLS CUI-1
C1562036
Ciclosporin
Description

Note: This question is critical for the further course of the questionnaire.

Data type

integer

Alias
UMLS CUI [1]
C0010592
Pimecrolimus
Description

Note: This question is critical for the further course of the questionnaire.

Data type

integer

Alias
UMLS CUI [1]
C1099414
Tacrolimus
Description

Note: This question is critical for the further course of the questionnaire.

Data type

integer

Alias
UMLS CUI [1]
C0085149
Inhibitors: Interleukin inhibitor
Description

Inhibitors: Interleukin inhibitor

Alias
UMLS CUI-1
C3653320
Anakinra
Description

Note: This question is critical for the further course of the questionnaire.

Data type

integer

Alias
UMLS CUI [1]
C0245109
Inhibitors: JAK inhibitors
Description

Inhibitors: JAK inhibitors

Alias
UMLS CUI-1
C3854325
Baricitinib
Description

Note: This question is critical for the further course of the questionnaire.

Data type

integer

Alias
UMLS CUI [1]
C4044947
Fedratinib
Description

Note: This question is critical for the further course of the questionnaire.

Data type

integer

Alias
UMLS CUI [1]
C3886623
Ruxolitinib
Description

Note: This question is critical for the further course of the questionnaire.

Data type

integer

Alias
UMLS CUI [1]
C2931926
Tofacitinib
Description

Note: This question is critical for the further course of the questionnaire.

Data type

integer

Alias
UMLS CUI [1]
C2930696
Upadacitinib
Description

Note: This question is critical for the further course of the questionnaire.

Data type

integer

Alias
UMLS CUI [1]
C4726929
Inhibitors: mTOR inhibitors
Description

Inhibitors: mTOR inhibitors

Alias
UMLS CUI-1
C2746052
Everolimus
Description

Note: This question is critical for the further course of the questionnaire.

Data type

integer

Alias
UMLS CUI [1]
C0541315
Sirolimus
Description

Note: This question is critical for the further course of the questionnaire.

Data type

integer

Alias
UMLS CUI [1]
C0072980
Inhibitor: PDE-4-inhibitor
Description

Inhibitor: PDE-4-inhibitor

Alias
UMLS CUI-1
C2936609
Apremilast
Description

Note: This question is critical for the further course of the questionnaire.

Data type

integer

Alias
UMLS CUI [1]
C1678805
Other Inhibitors
Description

Other Inhibitors

Alias
UMLS CUI-1
C0205394
UMLS CUI-2
C0243077
Other inhibitors
Description

Note: This question is critical for the further course of the questionnaire.

Data type

integer

Alias
UMLS CUI [1,1]
C0205394
UMLS CUI [1,2]
C0243077
Other, please specify
Description

Note: This question is critical for the further course of the questionnaire.

Data type

text

Alias
UMLS CUI [1,1]
C0205394
UMLS CUI [1,2]
C1521902
UMLS CUI [1,3]
C0243077
Other immunsuppressive regimens: Corticosteroids
Description

Other immunsuppressive regimens: Corticosteroids

Alias
UMLS CUI-1
C0021081
UMLS CUI-2
C0205394
UMLS CUI-3
C0001617
< 10 mg / d prednisolone equivalent
Description

Note: This question is critical for the further course of the questionnaire.

Data type

integer

Alias
UMLS CUI [1,1]
C0445550
UMLS CUI [1,2]
C0038317
10 - 100 mg / d prednisolone equivalent
Description

Note: This question is critical for the further course of the questionnaire.

Data type

integer

Alias
UMLS CUI [1]
C0038317
> 100 mg / d prednisolone equivalent
Description

Note: This question is critical for the further course of the questionnaire.

Data type

integer

Alias
UMLS CUI [1,1]
C0038317
UMLS CUI [1,2]
C0444956
Other immunsuppressive regimens: Fumarate
Description

Other immunsuppressive regimens: Fumarate

Alias
UMLS CUI-1
C0021081
UMLS CUI-2
C0205394
UMLS CUI-3
C0220833
Dimethyl fumarate
Description

Note: This question is critical for the further course of the questionnaire.

Data type

integer

Alias
UMLS CUI [1]
C0058218
Dimethyl fumarate / ethyl hydrogen fumarate
Description

Note: This question is critical for the further course of the questionnaire.

Data type

integer

Alias
UMLS CUI [1]
C0058218
UMLS CUI [2]
C0059764
Other immunsuppressive regimens: Immunosuppressive / immunomodulatory regimens
Description

Other immunsuppressive regimens: Immunosuppressive / immunomodulatory regimens

Alias
UMLS CUI-1
C1963758
UMLS CUI-2
C0205394
UMLS CUI-3
C0021081
Immunoglobulins i.v.
Description

Note: This question is critical for the further course of the questionnaire.

Data type

integer

Alias
UMLS CUI [1,1]
C0021027
UMLS CUI [1,2]
C0348016
Immunoglobulins s.c.
Description

Note: This question is critical for the further course of the questionnaire.

Data type

integer

Alias
UMLS CUI [1,1]
C0021027
UMLS CUI [1,2]
C0021499
Other immunsuppressive regimens: Interferon
Description

Other immunsuppressive regimens: Interferon

Alias
UMLS CUI-1
C0021081
UMLS CUI-2
C0205394
UMLS CUI-3
C3652465
Interferon-alpha
Description

Note: This question is critical for the further course of the questionnaire.

Data type

integer

Alias
UMLS CUI [1]
C0002199
Interferon-beta
Description

Note: This question is critical for the further course of the questionnaire.

Data type

integer

Alias
UMLS CUI [1]
C0015980
Other Immunsuppressive regimens: Other MS drugs
Description

Other Immunsuppressive regimens: Other MS drugs

Alias
UMLS CUI-1
C0021081
UMLS CUI-2
C0205394
UMLS CUI-3
C0013227
UMLS CUI-4
C0026769
Glatirameracetat
Description

Note: This question is critical for the further course of the questionnaire.

Data type

integer

Alias
UMLS CUI [1]
C0289884
Other Immunsuppressive regimens: Sphingosine-1-phosphate receptor modulators
Description

Other Immunsuppressive regimens: Sphingosine-1-phosphate receptor modulators

Alias
UMLS CUI-1
C0021081
UMLS CUI-2
C0205394
UMLS CUI-3
C4760638
Fingolimod
Description

Note: This question is critical for the further course of the questionnaire.

Data type

integer

Alias
UMLS CUI [1]
C1699926
Siponimod
Description

Note: This question is critical for the further course of the questionnaire.

Data type

integer

Alias
UMLS CUI [1]
C3657824
Other immunosuppressive regimens: Other
Description

Other immunosuppressive regimens: Other

Alias
UMLS CUI-1
C0205394
UMLS CUI-2
C0021081
Other Immunsuppressive agents
Description

Note: This question is critical for the further course of the questionnaire.

Data type

integer

Alias
UMLS CUI [1,1]
C0021081
UMLS CUI [1,2]
C0205394
Other, please specify
Description

Note: This question is critical for the further course of the questionnaire.

Data type

text

Alias
UMLS CUI [1,1]
C0021081
UMLS CUI [1,2]
C0205394
UMLS CUI [1,3]
C1521902
Immunosuppressive drugs: Underlying disease
Description

Immunosuppressive drugs: Underlying disease

Alias
UMLS CUI-1
C0021081
UMLS CUI-2
C0277554
Multiple Sclerosis
Description

Note: This question is critical for the further course of the questionnaire.

Data type

integer

Alias
UMLS CUI [1]
C0026769
Other neurological autoimmune diseases
Description

Note: This question is critical for the further course of the questionnaire.

Data type

integer

Alias
UMLS CUI [1,1]
C0205494
UMLS CUI [1,2]
C0004364
UMLS CUI [1,3]
C0205394
Oncology
Description

Note: This question is critical for the further course of the questionnaire.

Data type

integer

Alias
UMLS CUI [1]
C0205478
Organ transplantation
Description

Note: This question is critical for the further course of the questionnaire.

Data type

integer

Alias
UMLS CUI [1]
C0029216
Rheumatic diseases
Description

Note: This question is critical for the further course of the questionnaire.

Data type

integer

Alias
UMLS CUI [1]
C3495832
Other Underlying disease
Description

Note: This question is critical for the further course of the questionnaire.

Data type

integer

Alias
UMLS CUI [1,1]
C0277554
UMLS CUI [1,2]
C0205394
Other, please specify:
Description

Note: This question is critical for the further course of the questionnaire.

Data type

integer

Alias
UMLS CUI [1,1]
C0277554
UMLS CUI [1,2]
C0205394
UMLS CUI [1,3]
C1521902
Unknown underlying disease
Description

Note: This question is critical for the further course of the questionnaire.

Data type

integer

Alias
UMLS CUI [1,1]
C0439673
UMLS CUI [1,2]
C0277554
Is data entry for this section finished?
Description

Is data entry for this section finished?

Alias
UMLS CUI-1
C4684556
UMLS CUI-2
C1828479
UMLS CUI-3
C0205197
Is data entry for this section finished?
Description

Is data entry for this section finished?

Data type

integer

Alias
UMLS CUI [1,1]
C4684556
UMLS CUI [1,2]
C1828479
UMLS CUI [1,3]
C0205197
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Similar models

Immunsuppressive drug-related data

1 forms
Name
Type
Description | Question | Decode (Coded Value)
Data type
Alias
Item Group
Antibodies: Anti-CD20
C3891557 (UMLS CUI-1)
Item
Obinutuzumab (in the last 6 months)
integer
C2742503 (UMLS CUI [1,1])
C0332185 (UMLS CUI [1,2])
Obinutuzumab (in the last 6 months)
Code List
Obinutuzumab (in the last 6 months)
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Ocrelizumab (in the last 6 months)
integer
C1882138 (UMLS CUI [1,1])
C0332185 (UMLS CUI [1,2])
Ocrelizumab (in the last 6 months)
Code List
Ocrelizumab (in the last 6 months)
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Ofatumumab (in the last 3 months)
integer
C1832027 (UMLS CUI [1,1])
C0332185 (UMLS CUI [1,2])
Ofatumumab (in the last 3 months)
Code List
Ofatumumab (in the last 3 months)
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Rituximab (in the last 6 months)
integer
C0393022 (UMLS CUI [1,1])
C0332185 (UMLS CUI [1,2])
Rituximab (in the last 6 months)
Code List
Rituximab (in the last 6 months)
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item Group
Antibodies: CD-22
C0003241 (UMLS CUI-1)
C0054947 (UMLS CUI-2)
Item
Inotuzumab-Ozogamicin
integer
C1567130 (UMLS CUI [1])
Inotuzumab-Ozogamicin
Code List
Inotuzumab-Ozogamicin
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item Group
Antibodies: CD-38
C0003241 (UMLS CUI-1)
C0075742 (UMLS CUI-2)
Item
Daratumumab
integer
C2346801 (UMLS CUI [1])
Daratumumab
Code List
Daratumumab
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item Group
Antibodies: CD-52
C0003241 (UMLS CUI-1)
C1610534 (UMLS CUI-2)
Item
Alemtuzumab (in the last 12 months)
integer
C0383429 (UMLS CUI [1,1])
C0332185 (UMLS CUI [1,2])
Alemtuzumab (in the last 12 months)
Code List
Alemtuzumab (in the last 12 months)
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item Group
Antibodies: Anti-CD79b
C0104979 (UMLS CUI-1)
C0003241 (UMLS CUI-2)
Item
Polatuzumab-Vedotin
integer
C4078806 (UMLS CUI [1])
Polatuzumab-Vedotin
Code List
Polatuzumab-Vedotin
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item Group
Antibodies: B Lymphocyte stimulator-specific inhibitor (BLyS)
C0003241 (UMLS CUI-1)
C3160093 (UMLS CUI-2)
Item
Belimumab (in the last 6 months)
integer
C1723401 (UMLS CUI [1,1])
C0332185 (UMLS CUI [1,2])
Belimumab (in the last 6 months)
Code List
Belimumab (in the last 6 months)
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item Group
Antibodies: CD19-BiTE
C0003241 (UMLS CUI-1)
C4727095 (UMLS CUI-2)
Item
Blinatumomab
integer
C3853839 (UMLS CUI [1])
Blinatumomab
Code List
Blinatumomab
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item Group
Antibodies: Complement inhibitors
C0003241 (UMLS CUI-1)
C1564892 (UMLS CUI-2)
Item
Crovalimab
integer
C1564892 (UMLS CUI [1,1])
C3846158 (UMLS CUI [1,2])
Crovalimab
Code List
Crovalimab
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Eculizumab
integer
C1541483 (UMLS CUI [1])
Eculizumab
Code List
Eculizumab
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Pegcetacoplan (APL-2)
integer
C4053680 (UMLS CUI [1])
Pegcetacoplan (APL-2)
Code List
Pegcetacoplan (APL-2)
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Ravulizumab
integer
C4550350 (UMLS CUI [1])
Ravulizumab
Code List
Ravulizumab
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item Group
Antibodies: Co-stimulation inhibitors
C0003241 (UMLS CUI-1)
C1622572 (UMLS CUI-2)
C1999216 (UMLS CUI-3)
Item
Abatacept
integer
C1619966 (UMLS CUI [1])
Abatacept
Code List
Abatacept
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Belatacept
integer
C1619962 (UMLS CUI [1])
Belatacept
Code List
Belatacept
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item Group
Antibodies: Integrin antagonists
C0003241 (UMLS CUI-1)
C2917367 (UMLS CUI-2)
Item
Natalizumab
integer
C1172734 (UMLS CUI [1])
Natalizumab
Code List
Natalizumab
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Vedolizumab
integer
C2742797 (UMLS CUI [1])
Vedolizumab
Code List
Vedolizumab
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item Group
Antibodies: Interleukin inhibitors
C3653320 (UMLS CUI-1)
C0003241 (UMLS CUI-2)
Item
Basiliximab
integer
C0676831 (UMLS CUI [1])
Basiliximab
Code List
Basiliximab
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Canakinumab
integer
C2718773 (UMLS CUI [1])
Canakinumab
Code List
Canakinumab
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Ixekizumab
integer
C3489764 (UMLS CUI [1])
Ixekizumab
Code List
Ixekizumab
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Sarilumab
integer
C3885145 (UMLS CUI [1])
Sarilumab
Code List
Sarilumab
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Secukinumab
integer
C3179547 (UMLS CUI [1])
Secukinumab
Code List
Secukinumab
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Tocilizumab
integer
C1609165 (UMLS CUI [1])
Tocilizumab
Code List
Tocilizumab
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Ustekinumab
integer
C1608841 (UMLS CUI [1])
Ustekinumab
Code List
Ustekinumab
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item Group
Antibodies: TNF-alpha inhibitors
C3653350 (UMLS CUI-1)
C0003241 (UMLS CUI-2)
Item
Adalimumab
integer
C1122087 (UMLS CUI [1])
Adalimumab
Code List
Adalimumab
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Certolizumab
integer
C1872109 (UMLS CUI [1])
Certolizumab
Code List
Certolizumab
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Etanercept
integer
C0717758 (UMLS CUI [1])
Etanercept
Code List
Etanercept
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Golimumab
integer
C2353893 (UMLS CUI [1])
Golimumab
Code List
Golimumab
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Infliximab
integer
C0666743 (UMLS CUI [1])
Infliximab
Code List
Infliximab
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item Group
Other Antibodies
C0003241 (UMLS CUI-1)
C0205394 (UMLS CUI-2)
Item
Other Antibodies
integer
C0003241 (UMLS CUI [1,1])
C0205394 (UMLS CUI [1,2])
Other Antibodies
Code List
Other Antibodies
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Other Antibodies, to specify
Item
Other, please specify:
text
C0205394 (UMLS CUI [1,1])
C1521902 (UMLS CUI [1,2])
C0003241 (UMLS CUI [1,3])
Item Group
Chemotherapeutics: Antimetabolites
C0003376 (UMLS CUI-1)
C0729502 (UMLS CUI-2)
Item
6-Mercaptopurine
integer
C0000618 (UMLS CUI [1])
6-Mercaptopurine
Code List
6-Mercaptopurine
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Azathioprine
integer
C0004482 (UMLS CUI [1])
Azathioprine
Code List
Azathioprine
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Leflunomide
integer
C0063041 (UMLS CUI [1])
Leflunomide
Code List
Leflunomide
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Methotrexate
integer
C0025677 (UMLS CUI [1])
Methotrexate
Code List
Methotrexate
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Mycophenolate mofetil / Mycophenolic acid
integer
C0209368 (UMLS CUI [1])
C0026933 (UMLS CUI [2])
Mycophenolate mofetil / Mycophenolic acid
Code List
Mycophenolate mofetil / Mycophenolic acid
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Sulfasalazine
integer
C0036078 (UMLS CUI [1])
Sulfasalazine
Code List
Sulfasalazine
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Teriflunomide
integer
C1718383 (UMLS CUI [1])
Teriflunomide
Code List
Teriflunomide
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item Group
Chemotherapeutics: Cytostatics
C0010858 (UMLS CUI-1)
C0729502 (UMLS CUI-2)
Item
Cladribine (2-CDA) i.v./s.c. (in the last 12 months)
integer
C0092801 (UMLS CUI [1,1])
C0348016 (UMLS CUI [1,2])
C0332185 (UMLS CUI [1,3])
C0092801 (UMLS CUI [2,1])
C0021499 (UMLS CUI [2,2])
C0332185 (UMLS CUI [2,3])
Cladribine (2-CDA) i.v./s.c. (in the last 12 months)
Code List
Cladribine (2-CDA) i.v./s.c. (in the last 12 months)
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Cladribine (2-CDA) p.o. (in the last 12 months)
integer
C0092801 (UMLS CUI [1,1])
C0001563 (UMLS CUI [1,2])
C0332185 (UMLS CUI [1,3])
Cladribine (2-CDA) p.o. (in the last 12 months)
Code List
Cladribine (2-CDA) p.o. (in the last 12 months)
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Cyclophosphamide i.v.(in the last 3 months)
integer
C0010583 (UMLS CUI [1,1])
C0348016 (UMLS CUI [1,2])
C0332185 (UMLS CUI [1,3])
Cyclophosphamide i.v.(in the last 3 months)
Code List
Cyclophosphamide i.v.(in the last 3 months)
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Cyclophosphamide p.o. (in the last 3 months)
integer
C0010583 (UMLS CUI [1,1])
C0001563 (UMLS CUI [1,2])
C0332185 (UMLS CUI [1,3])
Cyclophosphamide p.o. (in the last 3 months)
Code List
Cyclophosphamide p.o. (in the last 3 months)
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Mitoxantrone (in the last 3 months)
integer
C0026259 (UMLS CUI [1,1])
C0332185 (UMLS CUI [1,2])
Mitoxantrone (in the last 3 months)
Code List
Mitoxantrone (in the last 3 months)
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item Group
Other Chemotherapeutics
C0205394 (UMLS CUI-1)
C0729502 (UMLS CUI-2)
Item
Other Chemotherapeutics
integer
C0205394 (UMLS CUI [1,1])
C0729502 (UMLS CUI [1,2])
Other Chemotherapeutics
Code List
Other Chemotherapeutics
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Other Chemotherapeutics, to specify
Item
Other, please specify:
text
C0729502 (UMLS CUI [1,1])
C0205394 (UMLS CUI [1,2])
C1521902 (UMLS CUI [1,3])
Item Group
Inhibitors: Calcineurin inhibitors
C1562036 (UMLS CUI-1)
Item
Ciclosporin
integer
C0010592 (UMLS CUI [1])
Ciclosporin
Code List
Ciclosporin
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Pimecrolimus
integer
C1099414 (UMLS CUI [1])
Pimercrolimus
Code List
Pimecrolimus
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Tacrolimus
integer
C0085149 (UMLS CUI [1])
Tacrolimus
Code List
Tacrolimus
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item Group
Inhibitors: Interleukin inhibitor
C3653320 (UMLS CUI-1)
Item
Anakinra
integer
C0245109 (UMLS CUI [1])
Anakinra
Code List
Anakinra
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item Group
Inhibitors: JAK inhibitors
C3854325 (UMLS CUI-1)
Item
Baricitinib
integer
C4044947 (UMLS CUI [1])
Baricitinib
Code List
Baricitinib
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Fedratinib
integer
C3886623 (UMLS CUI [1])
Fedratinib
Code List
Fedratinib
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Ruxolitinib
integer
C2931926 (UMLS CUI [1])
Ruxolitinib
Code List
Ruxolitinib
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Tofacitinib
integer
C2930696 (UMLS CUI [1])
Tofacitinib
Code List
Tofacitinib
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Upadacitinib
integer
C4726929 (UMLS CUI [1])
Upadacitinib
Code List
Upadacitinib
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item Group
Inhibitors: mTOR inhibitors
C2746052 (UMLS CUI-1)
Item
Everolimus
integer
C0541315 (UMLS CUI [1])
Everolimus
Code List
Everolimus
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Sirolimus
integer
C0072980 (UMLS CUI [1])
Sirolimus
Code List
Sirolimus
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item Group
Inhibitor: PDE-4-inhibitor
C2936609 (UMLS CUI-1)
Item
Apremilast
integer
C1678805 (UMLS CUI [1])
Apremilast
Code List
Apremilast
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item Group
Other Inhibitors
C0205394 (UMLS CUI-1)
C0243077 (UMLS CUI-2)
Item
Other inhibitors
integer
C0205394 (UMLS CUI [1,1])
C0243077 (UMLS CUI [1,2])
Other inhibitors
Code List
Other inhibitors
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Other inhibitors, to specify
Item
Other, please specify
text
C0205394 (UMLS CUI [1,1])
C1521902 (UMLS CUI [1,2])
C0243077 (UMLS CUI [1,3])
Item Group
Other immunsuppressive regimens: Corticosteroids
C0021081 (UMLS CUI-1)
C0205394 (UMLS CUI-2)
C0001617 (UMLS CUI-3)
Item
< 10 mg / d prednisolone equivalent
integer
C0445550 (UMLS CUI [1,1])
C0038317 (UMLS CUI [1,2])
< 10 mg / d prednisolone equivalent
Code List
< 10 mg / d prednisolone equivalent
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
10 - 100 mg / d prednisolone equivalent
integer
C0038317 (UMLS CUI [1])
10 - 100 mg / d prednisolone equivalent
Code List
10 - 100 mg / d prednisolone equivalent
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
> 100 mg / d prednisolone equivalent
integer
C0038317 (UMLS CUI [1,1])
C0444956 (UMLS CUI [1,2])
10 - 100 mg / d prednisolone equivalent
Code List
> 100 mg / d prednisolone equivalent
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item Group
Other immunsuppressive regimens: Fumarate
C0021081 (UMLS CUI-1)
C0205394 (UMLS CUI-2)
C0220833 (UMLS CUI-3)
Item
Dimethyl fumarate
integer
C0058218 (UMLS CUI [1])
Dimethyl fumarate
Code List
Dimethyl fumarate
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Dimethyl fumarate / ethyl hydrogen fumarate
integer
C0058218 (UMLS CUI [1])
C0059764 (UMLS CUI [2])
Dimethyl fumarate / ethyl hydrogen fumarate
Code List
Dimethyl fumarate / ethyl hydrogen fumarate
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item Group
Other immunsuppressive regimens: Immunosuppressive / immunomodulatory regimens
C1963758 (UMLS CUI-1)
C0205394 (UMLS CUI-2)
C0021081 (UMLS CUI-3)
Item
Immunoglobulins i.v.
integer
C0021027 (UMLS CUI [1,1])
C0348016 (UMLS CUI [1,2])
Immunoglobulins i.v.
Code List
Immunoglobulins i.v.
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Immunoglobulins s.c.
integer
C0021027 (UMLS CUI [1,1])
C0021499 (UMLS CUI [1,2])
Immunoglobulins s.c.
Code List
Immunoglobulins s.c.
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item Group
Other immunsuppressive regimens: Interferon
C0021081 (UMLS CUI-1)
C0205394 (UMLS CUI-2)
C3652465 (UMLS CUI-3)
Item
Interferon-alpha
integer
C0002199 (UMLS CUI [1])
Interferon-alpha
Code List
Interferon-alpha
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Interferon-beta
integer
C0015980 (UMLS CUI [1])
Interferon-beta
Code List
Interferon-beta
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item Group
Other Immunsuppressive regimens: Other MS drugs
C0021081 (UMLS CUI-1)
C0205394 (UMLS CUI-2)
C0013227 (UMLS CUI-3)
C0026769 (UMLS CUI-4)
Item
Glatirameracetat
integer
C0289884 (UMLS CUI [1])
Glatirameracetat
Code List
Glatirameracetat
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item Group
Other Immunsuppressive regimens: Sphingosine-1-phosphate receptor modulators
C0021081 (UMLS CUI-1)
C0205394 (UMLS CUI-2)
C4760638 (UMLS CUI-3)
Item
Fingolimod
integer
C1699926 (UMLS CUI [1])
Fingolimod
Code List
Fingolimod
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Siponimod
integer
C3657824 (UMLS CUI [1])
Siponimod
Code List
Siponimod
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item Group
Other immunosuppressive regimens: Other
C0205394 (UMLS CUI-1)
C0021081 (UMLS CUI-2)
Item
Other Immunsuppressive agents
integer
C0021081 (UMLS CUI [1,1])
C0205394 (UMLS CUI [1,2])
Other Immunsuppressive agents
Code List
Other Immunsuppressive agents
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Other Immunsuppressive agents, to specify
Item
Other, please specify
text
C0021081 (UMLS CUI [1,1])
C0205394 (UMLS CUI [1,2])
C1521902 (UMLS CUI [1,3])
Item Group
Immunosuppressive drugs: Underlying disease
C0021081 (UMLS CUI-1)
C0277554 (UMLS CUI-2)
Item
Multiple Sclerosis
integer
C0026769 (UMLS CUI [1])
Multiple Sclerosis
Code List
Multiple Sclerosis
CL Item
not quoted (0)
CL Item
quoted (1)
Item
Other neurological autoimmune diseases
integer
C0205494 (UMLS CUI [1,1])
C0004364 (UMLS CUI [1,2])
C0205394 (UMLS CUI [1,3])
Other neurological autoimmune diseases
Code List
Other neurological autoimmune diseases
CL Item
not quoted (0)
CL Item
quoted (1)
Item
Oncology
integer
C0205478 (UMLS CUI [1])
Oncology
Code List
Oncology
CL Item
not quoted (0)
CL Item
quoted (1)
Item
Organ transplantation
integer
C0029216 (UMLS CUI [1])
Organ transplantation
Code List
Organ transplantation
CL Item
not quoted (0)
CL Item
quoted (1)
Item
Rheumatic diseases
integer
C3495832 (UMLS CUI [1])
Rheumatic diseases
Code List
Rheumatic diseases
CL Item
not quoted (0)
CL Item
quoted (1)
Item
Other Underlying disease
integer
C0277554 (UMLS CUI [1,1])
C0205394 (UMLS CUI [1,2])
Other Underlying disease
Code List
Other Underlying disease
CL Item
not quoted (0)
CL Item
quoted (1)
Item
Other, please specify:
integer
C0277554 (UMLS CUI [1,1])
C0205394 (UMLS CUI [1,2])
C1521902 (UMLS CUI [1,3])
Other Underlying disease
Code List
Other, please specify:
CL Item
not quoted (0)
CL Item
quoted (1)
Item
Unknown underlying disease
integer
C0439673 (UMLS CUI [1,1])
C0277554 (UMLS CUI [1,2])
Unknown underlying disease
Code List
Unknown underlying disease
CL Item
not quoted (0)
CL Item
quoted (1)
Item Group
Is data entry for this section finished?
C4684556 (UMLS CUI-1)
C1828479 (UMLS CUI-2)
C0205197 (UMLS CUI-3)
Item
Is data entry for this section finished?
integer
C4684556 (UMLS CUI [1,1])
C1828479 (UMLS CUI [1,2])
C0205197 (UMLS CUI [1,3])
Is data entry for this section finished?
Code List
Is data entry for this section finished?
CL Item
Yes (1)
CL Item
No (2)
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