ID

15158

Descrizione

The CoDe (”Coding of Death in HIV”) Project A significant proportion of deaths in HIV-1 infected persons are now caused by non-AIDS events. It is important to closely monitor the causes of death in this population in order to target interventions appropriately, should specific causes of death emerge or become predominant. It is possible that deaths from diseases related to an accelerated aging process will become more frequent. The same applies for causes of death related to co-infections (e.g. hepatitis) or other co-morbidities (e.g. sequelae of intravenous drug use). Furthermore, it is important to be able to evaluate the risk factors for such emerging diseases, including their possible relationship with immunodeficiency. Until now there has not been a uniform classification system for causes of death in HIV patients. Studies have either created their own coding systems based o­n frequent and/or ‘important’ causes (e.g. rare but important adverse events such as lactic acidosis and pancreatitis), or have used ICD9 or ICD10 codes from death certificates. In many cases, the ICD system cannot be directly adapted to HIV infected persons. Many AIDS defining illnesses are poorly identified in the ICD system, and some diseases (e.g. CNS diseases) have a different aetiology in HIV patients and are therefore not covered by the ICD system, or at great risk of mis-classification. In July 2004, a meeting was held in Copenhagen with the participation from executive committees of a large number of pivotal observational studies and clinical trials that routinely collect data o­n causes of death. At this meeting, it became clear that there was a need for a harmonization and standardization of the approach taken when collecting data o­n cause of death and when reviewing these deaths. As a result, the CoDe Project was initiated. The CoDe Project is a uniform coding system that can be applied to studies of individuals with HIV infection, including a detailed data collection o­n the causes of death and contributing factors, as well as a centralised review process of the data collected. http://www.cphiv.dk/Tools-Standards/CoDe/About Contains: Risk factors, co-morbidities

collegamento

http://www.cphiv.dk/Tools-Standards/CoDe/About

Keywords

  1. 20/05/16 20/05/16 -
  2. 20/05/16 20/05/16 -
  3. 07/06/16 07/06/16 -
Caricato su

20 maggio 2016

DOI

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Licenza

Creative Commons BY-NC 3.0

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Determining factor The CoDe (”Coding of Death in HIV”) Project

Determining factor

  1. StudyEvent: ODM
    1. Determining factor
Ongoing risk factors in the year prior to death:
Descrizione

Ongoing risk factors in the year prior to death:

Cigarette smoking
Descrizione

Cigarette smoking

Tipo di dati

text

Alias
UMLS CUI [1]
C0543414
Excessive alcohol consumption
Descrizione

Excessive alcohol consumption

Tipo di dati

text

Alias
UMLS CUI [1]
C0001948
Active illicit injecting drug use
Descrizione

Active illicit injecting drug use

Tipo di dati

text

Alias
UMLS CUI [1]
C0556025
Active illicit non-injecting drug use
Descrizione

Active illicit non-injecting drug use

Tipo di dati

text

Alias
UMLS CUI [1]
C0242510
Opiate substitution (methadone)
Descrizione

Opiate substitution (methadone)

Tipo di dati

text

Alias
UMLS CUI [1]
C0746569
Comorbidities - Ongoing chronic conditions:
Descrizione

Comorbidities - Ongoing chronic conditions:

Hypertension
Descrizione

Hypertension

Tipo di dati

text

Alias
UMLS CUI [1]
C0020538
Diabetes mellitus
Descrizione

Diabetes mellitus

Tipo di dati

text

Alias
UMLS CUI [1]
C0011849
Dyslipidemia
Descrizione

Dyslipidemia

Tipo di dati

text

Alias
UMLS CUI [1]
C0242339
Comorbidities Prior cardiovascular Disease
Descrizione

Comorbidities Prior cardiovascular Disease

Prior Cardiovascular Disease (myocardial infarction, stroke or invasive cardiovascular procedure)
Descrizione

Prior Cardiovascular Disease

Tipo di dati

text

Alias
UMLS CUI [1]
C0455539
Comorbidities History of depression
Descrizione

Comorbidities History of depression

History of depression
Descrizione

History of depression

Tipo di dati

text

Alias
UMLS CUI [1]
C0455503
Comorbidities History of psychosis
Descrizione

Comorbidities History of psychosis

History of psychosis
Descrizione

History of psychosis

Tipo di dati

text

Alias
UMLS CUI [1]
C3887134
Comorbidities Liver Disease
Descrizione

Comorbidities Liver Disease

Chronic elevation of liver transaminases
Descrizione

Chronic elevation of liver transaminases

Tipo di dati

text

Alias
UMLS CUI [1]
C0438717
Chronic HBV infection
Descrizione

Chronic HBV infection

Tipo di dati

text

Alias
UMLS CUI [1]
C0524909
Chronic HCV infection
Descrizione

Chronic HCV infection

Tipo di dati

text

Alias
UMLS CUI [1]
C0524910
HDV infection
Descrizione

HDV infection

Tipo di dati

text

Alias
UMLS CUI [1]
C0011226
History of previous liver decompensation
Descrizione

History of previous liver decompensation

Tipo di dati

text

Alias
UMLS CUI [1,1]
C0455483
UMLS CUI [1,2]
C0085605
Clinical signs of liver failure in the 4 weeks before death
Descrizione

Clinical signs of liver failure in the 4 weeks before death

Tipo di dati

text

Alias
UMLS CUI [1,1]
C0085605
UMLS CUI [1,2]
C0439230
UMLS CUI [1,3]
C0332152
UMLS CUI [1,4]
C0011065
Liver histology available (ever)
Descrizione

Liver histology available (ever)

Tipo di dati

text

Alias
UMLS CUI [1]
C0586689

Similar models

Determining factor

  1. StudyEvent: ODM
    1. Determining factor
Name
genere
Description | Question | Decode (Coded Value)
Tipo di dati
Alias
Item Group
Ongoing risk factors in the year prior to death:
Item
Cigarette smoking
text
C0543414 (UMLS CUI [1])
Code List
Cigarette smoking
CL Item
Yes (Yes)
CL Item
No  (No )
CL Item
Unknown (Unknown)
Item
Excessive alcohol consumption
text
C0001948 (UMLS CUI [1])
Code List
Excessive alcohol consumption
CL Item
Yes (Yes)
CL Item
No  (No )
CL Item
Unknown (Unknown)
Item
Active illicit injecting drug use
text
C0556025 (UMLS CUI [1])
Code List
Active illicit injecting drug use
CL Item
Yes (Yes)
CL Item
No  (No )
CL Item
Unknown (Unknown)
Item
Active illicit non-injecting drug use
text
C0242510 (UMLS CUI [1])
Code List
Active illicit non-injecting drug use
CL Item
Yes (Yes)
CL Item
No  (No )
CL Item
Unknown (Unknown)
Item
Opiate substitution (methadone)
text
C0746569 (UMLS CUI [1])
Code List
Opiate substitution (methadone)
CL Item
Yes (Yes)
CL Item
No  (No )
CL Item
Unknown (Unknown)
Item Group
Comorbidities - Ongoing chronic conditions:
Item
Hypertension
text
C0020538 (UMLS CUI [1])
Code List
Hypertension
CL Item
Yes (Yes)
CL Item
No  (No )
CL Item
Unknown (Unknown)
Item
Diabetes mellitus
text
C0011849 (UMLS CUI [1])
Code List
Diabetes mellitus
CL Item
Yes (Yes)
CL Item
No  (No )
CL Item
Unknown (Unknown)
Item
Dyslipidemia
text
C0242339 (UMLS CUI [1])
Code List
Dyslipidemia
CL Item
Yes (Yes)
CL Item
No  (No )
CL Item
Unknown (Unknown)
Item Group
Comorbidities Prior cardiovascular Disease
Item
Prior Cardiovascular Disease (myocardial infarction, stroke or invasive cardiovascular procedure)
text
C0455539 (UMLS CUI [1])
Code List
Prior Cardiovascular Disease (myocardial infarction, stroke or invasive cardiovascular procedure)
CL Item
Yes (Yes)
CL Item
No  (No )
CL Item
Unknown (Unknown)
Item Group
Comorbidities History of depression
Item
History of depression
text
C0455503 (UMLS CUI [1])
Code List
History of depression
CL Item
Yes (Yes)
CL Item
No  (No )
CL Item
Unknown (Unknown)
Item Group
Comorbidities History of psychosis
Item
History of psychosis
text
C3887134 (UMLS CUI [1])
Code List
History of psychosis
CL Item
Yes (Yes)
CL Item
No  (No )
CL Item
Unknown (Unknown)
Item Group
Comorbidities Liver Disease
Item
Chronic elevation of liver transaminases
text
C0438717 (UMLS CUI [1])
Code List
Chronic elevation of liver transaminases
CL Item
Yes (Yes)
CL Item
No  (No )
CL Item
Unknown (Unknown)
Item
Chronic HBV infection
text
C0524909 (UMLS CUI [1])
Code List
Chronic HBV infection
CL Item
Yes (Yes)
CL Item
No  (No )
CL Item
Unknown (Unknown)
Item
Chronic HCV infection
text
C0524910 (UMLS CUI [1])
Code List
Chronic HCV infection
CL Item
Yes (Yes)
CL Item
No  (No )
CL Item
Unknown (Unknown)
Item
HDV infection
text
C0011226 (UMLS CUI [1])
Code List
HDV infection
CL Item
Yes (Yes)
CL Item
No  (No )
CL Item
Unknown (Unknown)
Item
History of previous liver decompensation
text
C0455483 (UMLS CUI [1,1])
C0085605 (UMLS CUI [1,2])
Code List
History of previous liver decompensation
CL Item
Yes (Yes)
CL Item
No  (No )
CL Item
Unknown (Unknown)
Item
Clinical signs of liver failure in the 4 weeks before death
text
C0085605 (UMLS CUI [1,1])
C0439230 (UMLS CUI [1,2])
C0332152 (UMLS CUI [1,3])
C0011065 (UMLS CUI [1,4])
Code List
Clinical signs of liver failure in the 4 weeks before death
CL Item
Yes (Yes)
CL Item
No  (No )
CL Item
Unknown (Unknown)
Item
Liver histology available (ever)
text
C0586689 (UMLS CUI [1])
Code List
Liver histology available (ever)
CL Item
Yes (Yes)
CL Item
No  (No )
CL Item
Unknown (Unknown)

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