ID

15160

Description

The CoDe (”Coding of Death in HIV”) Project A significant proportion of deaths in HIV-1 infected persons are now caused by non-AIDS events. It is important to closely monitor the causes of death in this population in order to target interventions appropriately, should specific causes of death emerge or become predominant. It is possible that deaths from diseases related to an accelerated aging process will become more frequent. The same applies for causes of death related to co-infections (e.g. hepatitis) or other co-morbidities (e.g. sequelae of intravenous drug use). Furthermore, it is important to be able to evaluate the risk factors for such emerging diseases, including their possible relationship with immunodeficiency. Until now there has not been a uniform classification system for causes of death in HIV patients. Studies have either created their own coding systems based o­n frequent and/or ‘important’ causes (e.g. rare but important adverse events such as lactic acidosis and pancreatitis), or have used ICD9 or ICD10 codes from death certificates. In many cases, the ICD system cannot be directly adapted to HIV infected persons. Many AIDS defining illnesses are poorly identified in the ICD system, and some diseases (e.g. CNS diseases) have a different aetiology in HIV patients and are therefore not covered by the ICD system, or at great risk of mis-classification. In July 2004, a meeting was held in Copenhagen with the participation from executive committees of a large number of pivotal observational studies and clinical trials that routinely collect data o­n causes of death. At this meeting, it became clear that there was a need for a harmonization and standardization of the approach taken when collecting data o­n cause of death and when reviewing these deaths. As a result, the CoDe Project was initiated. The CoDe Project is a uniform coding system that can be applied to studies of individuals with HIV infection, including a detailed data collection o­n the causes of death and contributing factors, as well as a centralised review process of the data collected. http://www.cphiv.dk/Tools-Standards/CoDe/About Contains: Risk factors, co-morbidities

Link

http://www.cphiv.dk/Tools-Standards/CoDe/About

Keywords

  1. 5/20/16 5/20/16 -
  2. 5/20/16 5/20/16 -
  3. 6/7/16 6/7/16 -
Uploaded on

May 20, 2016

DOI

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License

Creative Commons BY-NC 3.0

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Determining factor The CoDe (”Coding of Death in HIV”) Project

Determining factor

  1. StudyEvent: ODM
    1. Determining factor
Ongoing risk factors in the year prior to death:
Description

Ongoing risk factors in the year prior to death:

Cigarette smoking
Description

Cigarette smoking

Data type

text

Alias
UMLS CUI [1]
C0543414
Excessive alcohol consumption
Description

Excessive alcohol consumption

Data type

text

Alias
UMLS CUI [1]
C0001948
Active illicit injecting drug use
Description

Active illicit injecting drug use

Data type

text

Alias
UMLS CUI [1]
C0556025
Active illicit non-injecting drug use
Description

Active illicit non-injecting drug use

Data type

text

Alias
UMLS CUI [1]
C0242510
Opiate substitution (methadone)
Description

Opiate substitution (methadone)

Data type

text

Alias
UMLS CUI [1]
C0746569
Comorbidities - Ongoing chronic conditions:
Description

Comorbidities - Ongoing chronic conditions:

Hypertension
Description

Hypertension

Data type

text

Alias
UMLS CUI [1]
C0020538
Diabetes mellitus
Description

Diabetes mellitus

Data type

text

Alias
UMLS CUI [1]
C0011849
Dyslipidemia
Description

Dyslipidemia

Data type

text

Alias
UMLS CUI [1]
C0242339
Comorbidities Prior cardiovascular Disease
Description

Comorbidities Prior cardiovascular Disease

Prior Cardiovascular Disease (myocardial infarction, stroke or invasive cardiovascular procedure)
Description

Prior Cardiovascular Disease

Data type

text

Alias
UMLS CUI [1]
C0455539
Comorbidities History of depression
Description

Comorbidities History of depression

History of depression
Description

History of depression

Data type

text

Alias
UMLS CUI [1]
C0455503
Comorbidities History of psychosis
Description

Comorbidities History of psychosis

History of psychosis
Description

History of psychosis

Data type

text

Alias
UMLS CUI [1]
C3887134
Comorbidities Liver Disease
Description

Comorbidities Liver Disease

Chronic elevation of liver transaminases
Description

Chronic elevation of liver transaminases

Data type

text

Alias
UMLS CUI [1]
C0438717
Chronic HBV infection
Description

Chronic HBV infection

Data type

text

Alias
UMLS CUI [1]
C0524909
Chronic HCV infection
Description

Chronic HCV infection

Data type

text

Alias
UMLS CUI [1]
C0524910
HDV infection
Description

HDV infection

Data type

text

Alias
UMLS CUI [1]
C0011226
History of previous liver decompensation
Description

History of previous liver decompensation

Data type

text

Alias
UMLS CUI [1,1]
C0455483
UMLS CUI [1,2]
C0085605
Clinical signs of liver failure in the 4 weeks before death
Description

Clinical signs of liver failure in the 4 weeks before death

Data type

text

Alias
UMLS CUI [1,1]
C0085605
UMLS CUI [1,2]
C0439230
UMLS CUI [1,3]
C0332152
UMLS CUI [1,4]
C0011065
Liver histology available (ever)
Description

Liver histology available (ever)

Data type

text

Alias
UMLS CUI [1]
C0586689
Date of Liver Biopsy
Description

If previous question "Yes", please indicate: the date of most recent biopsy

Data type

date

Alias
UMLS CUI [1,1]
C0011008
UMLS CUI [1,2]
C0586689
Stage of fibrosis (0-4)
Description

if "liver histology available (ever)" was "yes"

Data type

integer

Alias
UMLS CUI [1,1]
C1954435
UMLS CUI [1,2]
C0023884

Similar models

Determining factor

  1. StudyEvent: ODM
    1. Determining factor
Name
Type
Description | Question | Decode (Coded Value)
Data type
Alias
Item Group
Ongoing risk factors in the year prior to death:
Item
Cigarette smoking
text
C0543414 (UMLS CUI [1])
Code List
Cigarette smoking
CL Item
Yes (Yes)
CL Item
No  (No )
CL Item
Unknown (Unknown)
Item
Excessive alcohol consumption
text
C0001948 (UMLS CUI [1])
Code List
Excessive alcohol consumption
CL Item
Yes (Yes)
CL Item
No  (No )
CL Item
Unknown (Unknown)
Item
Active illicit injecting drug use
text
C0556025 (UMLS CUI [1])
Code List
Active illicit injecting drug use
CL Item
Yes (Yes)
CL Item
No  (No )
CL Item
Unknown (Unknown)
Item
Active illicit non-injecting drug use
text
C0242510 (UMLS CUI [1])
Code List
Active illicit non-injecting drug use
CL Item
Yes (Yes)
CL Item
No  (No )
CL Item
Unknown (Unknown)
Item
Opiate substitution (methadone)
text
C0746569 (UMLS CUI [1])
Code List
Opiate substitution (methadone)
CL Item
Yes (Yes)
CL Item
No  (No )
CL Item
Unknown (Unknown)
Item Group
Comorbidities - Ongoing chronic conditions:
Item
Hypertension
text
C0020538 (UMLS CUI [1])
Code List
Hypertension
CL Item
Yes (Yes)
CL Item
No  (No )
CL Item
Unknown (Unknown)
Item
Diabetes mellitus
text
C0011849 (UMLS CUI [1])
Code List
Diabetes mellitus
CL Item
Yes (Yes)
CL Item
No  (No )
CL Item
Unknown (Unknown)
Item
Dyslipidemia
text
C0242339 (UMLS CUI [1])
Code List
Dyslipidemia
CL Item
Yes (Yes)
CL Item
No  (No )
CL Item
Unknown (Unknown)
Item Group
Comorbidities Prior cardiovascular Disease
Item
Prior Cardiovascular Disease (myocardial infarction, stroke or invasive cardiovascular procedure)
text
C0455539 (UMLS CUI [1])
Code List
Prior Cardiovascular Disease (myocardial infarction, stroke or invasive cardiovascular procedure)
CL Item
Yes (Yes)
CL Item
No  (No )
CL Item
Unknown (Unknown)
Item Group
Comorbidities History of depression
Item
History of depression
text
C0455503 (UMLS CUI [1])
Code List
History of depression
CL Item
Yes (Yes)
CL Item
No  (No )
CL Item
Unknown (Unknown)
Item Group
Comorbidities History of psychosis
Item
History of psychosis
text
C3887134 (UMLS CUI [1])
Code List
History of psychosis
CL Item
Yes (Yes)
CL Item
No  (No )
CL Item
Unknown (Unknown)
Item Group
Comorbidities Liver Disease
Item
Chronic elevation of liver transaminases
text
C0438717 (UMLS CUI [1])
Code List
Chronic elevation of liver transaminases
CL Item
Yes (Yes)
CL Item
No  (No )
CL Item
Unknown (Unknown)
Item
Chronic HBV infection
text
C0524909 (UMLS CUI [1])
Code List
Chronic HBV infection
CL Item
Yes (Yes)
CL Item
No  (No )
CL Item
Unknown (Unknown)
Item
Chronic HCV infection
text
C0524910 (UMLS CUI [1])
Code List
Chronic HCV infection
CL Item
Yes (Yes)
CL Item
No  (No )
CL Item
Unknown (Unknown)
Item
HDV infection
text
C0011226 (UMLS CUI [1])
Code List
HDV infection
CL Item
Yes (Yes)
CL Item
No  (No )
CL Item
Unknown (Unknown)
Item
History of previous liver decompensation
text
C0455483 (UMLS CUI [1,1])
C0085605 (UMLS CUI [1,2])
Code List
History of previous liver decompensation
CL Item
Yes (Yes)
CL Item
No  (No )
CL Item
Unknown (Unknown)
Item
Clinical signs of liver failure in the 4 weeks before death
text
C0085605 (UMLS CUI [1,1])
C0439230 (UMLS CUI [1,2])
C0332152 (UMLS CUI [1,3])
C0011065 (UMLS CUI [1,4])
Code List
Clinical signs of liver failure in the 4 weeks before death
CL Item
Yes (Yes)
CL Item
No  (No )
CL Item
Unknown (Unknown)
Item
Liver histology available (ever)
text
C0586689 (UMLS CUI [1])
Code List
Liver histology available (ever)
CL Item
Yes (Yes)
CL Item
No  (No )
CL Item
Unknown (Unknown)
LiverBiopsyDate
Item
Date of Liver Biopsy
date
C0011008 (UMLS CUI [1,1])
C0586689 (UMLS CUI [1,2])
Item
Stage of fibrosis (0-4)
integer
C1954435 (UMLS CUI [1,1])
C0023884 (UMLS CUI [1,2])
Code List
Stage of fibrosis (0-4)
CL Item
0 (1)
CL Item
1 (2)
CL Item
2 (3)
CL Item
3 (4)
CL Item
4 (5)

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