ID

14701

Description

Participants are asked to fast for at least 9 hours (generally overnight) prior to the Oral Glucose Tolerance Test (OGTT). Participants are asked a series of exclusionary questions and then have an initial blood draw to determine Fasting Plasma Glucose levels. Participants are next asked to drink a calibrated dose (generally 75 grams/10 ounces) of a dextrose solution (e.g., Trutol®) and have a second venipuncture 2 hours (plus or minus 15 minutes) after the first venipuncture. The plasma is separated from the blood via centrifugation, and glucose concentration is determined via the hexokinase method. ODM derived from: https://cde.nlm.nih.gov Primary source: https://www.phenxtoolkit.org/ Recent publication: Hendershot, T., Pan, H., Haines, J., Harlan, W.R., Marazita, M.L., McCarty, C.A., Ramos, E.M., and Hamilton, C.M. (2015) Using the PhenX toolkit to add standard measures to a study. Curr. Protoc. Hum. Genet. 86:1.21.1-1.21.17. doi: 10.1002/0471142905.hg0121s86 Permission to publish granted by Carol M. Hamilton.

Link

https://cde.nlm.nih.gov

Keywords

Versions (1)
  1. 4/26/16 4/26/16 -
Uploaded on

April 26, 2016

DOI

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License

Creative Commons BY-NC 3.0
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Oral Glucose Tolerance Test Protocol PhenX Toolkit

English

Oral Glucose Tolerance Test Protocol PhenX Toolkit

1 forms  
PhenX - oral glucose tolerance test protocol
Description

PhenX - oral glucose tolerance test protocol

Alias
UMLS CUI-1
C3171861
Did you eat or drink anything other than plain water after 11:30 last night?
Description

eat or drink

Data type

integer

Alias
UMLS CUI [1]
C3176746
When did you last eat or drink anything other than plain water?
Description

last time eat or drink

Data type

datetime

Alias
UMLS CUI [1]
C3176748
Have you had any of the following since {insert time from 1 here}? Coffee or tea with cream and sugar? [Include milk or non-dairy creamers.]
Description

coffee tea

Data type

boolean

Alias
UMLS CUI [1]
C3176749
If Yes, record date
Description

coffee tea time

Data type

datetime

Alias
UMLS CUI [1]
C3176751
Have you had any of the following since {insert time from 1 here}? Alcohol, such as beer, wine, or liquor?
Description

alcohol

Data type

boolean

Alias
UMLS CUI [1]
C3176752
If Yes, record date
Description

alcohol time

Data type

datetime

Alias
UMLS CUI [1]
C3176754
Have you had any of the following since {insert time from 1 here}? Gum, breath mints, lozenges, or cough drops, or other cough or cold remedies?
Description

gum

Data type

boolean

Alias
UMLS CUI [1]
C3176013
If Yes, record date
Description

gum time

Data type

datetime

Alias
UMLS CUI [1]
C3176188
Have you had any of the following since {insert time from 1 here}? Antacids, laxatives, or anti-diarrheals?
Description

antacids

Data type

boolean

Alias
UMLS CUI [1]
C3176189
If Yes, record date
Description

anticids time

Data type

datetime

Alias
UMLS CUI [1]
C3176191
Have you had any of the following since {insert time from 1 here}? Dietary Supplements such as vitamins and minerals? [Include multivitamins and single nutrient supplements.]
Description

dietary supplements

Data type

boolean

Alias
UMLS CUI [1]
C3176023
If Yes, record date
Description

dietary supplements time

Data type

datetime

Alias
UMLS CUI [1]
C3176025
Are you currently pregnant?
Description

pregnancy

Data type

integer

Alias
UMLS CUI [1]
C0032961
{Is SP/Are you} now taking insulin?
Description

taking insulin

Data type

integer

Alias
UMLS CUI [1]
C3842788
{Is SP/Are you} now taking diabetic pills to lower {his/her}/your} blood sugar?
Description

diabetic pills

Data type

integer

Alias
UMLS CUI [1]
C3176196
Do you have hemophilia?
Description

hemophilia

Data type

integer

Alias
UMLS CUI [1]
C0684275
Have you received cancer chemotherapy in the past four weeks or do you anticipate such therapy in the next four weeks?
Description

chemotherapy

Data type

integer

Alias
UMLS CUI [1]
C0392920
Exclusion Criteria
Description

exclusion criteria

Data type

integer

Alias
UMLS CUI [1]
C0680251
Service comment: Record any comments about the blood draw, including any reasons for the tube not being drawn according to the protocol.
Description

service comment

Data type

text

Alias
UMLS CUI [1]
C0485795
Service comment: Record any comments about the blood draw, including any reasons for the tube not being drawn according to the protocol.
Description

service comment

Data type

text

Alias
UMLS CUI [1]
C0485795
Body weight
Description

body weight

Data type

float

Measurement units
  • kg
Alias
UMLS CUI [1]
C0005910
kg
Record the amount of dextrose solution administered
Description

amount of dextrose solution

Data type

float

Measurement units
  • ml
Alias
UMLS CUI [1]
C1165603
ml
Record the amount of dextrose solution the participant drank
Description

amount of dextrose solution the participant drank

Data type

integer

Alias
UMLS CUI [1]
C3176775
Record whether all of the solution was consumed in 10 minutes
Description

all of the solution was consumed in 10 minutes

Data type

integer

Alias
UMLS CUI [1]
C3176777
Record the number of minutes elapsed between consuming dextrose solution and administering the second blood draw
Description

minutes elapsed administering the second blood draw

Data type

float

Measurement units
  • min
Alias
UMLS CUI [1]
C3176778
min
Make of the equipment used to perform...
Description

make of equipment used

Data type

text

Alias
UMLS CUI [1]
C3176779
Manufacturer of the equipment used to perform...
Description

manufacturer of equipment used

Data type

text

Alias
UMLS CUI [1]
C3176781
Blood draw [PhenX]
Description

blood draw

Data type

text

Alias
UMLS CUI [1]
C3176783
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Similar models

Oral Glucose Tolerance Test Protocol PhenX Toolkit

1 forms
Name
Type
Description | Question | Decode (Coded Value)
Data type
Alias
Item Group
PhenX - oral glucose tolerance test protocol
C3171861 (UMLS CUI-1)
Item
Did you eat or drink anything other than plain water after 11:30 last night?
integer
C3176746 (UMLS CUI [1])
eat or drink
Code List
Did you eat or drink anything other than plain water after 11:30 last night?
CL Item
Yes (1)
C1705108 (UMLS CUI-1)
CL Item
No (2)
C1298908 (UMLS CUI-1)
CL Item
Refused (3)
C1705116 (UMLS CUI-1)
CL Item
Don't know (4)
C3843613 (UMLS CUI-1)
last time eat or drink
Item
When did you last eat or drink anything other than plain water?
datetime
C3176748 (UMLS CUI [1])
coffee tea
Item
Have you had any of the following since {insert time from 1 here}? Coffee or tea with cream and sugar? [Include milk or non-dairy creamers.]
boolean
C3176749 (UMLS CUI [1])
coffee tea time
Item
If Yes, record date
datetime
C3176751 (UMLS CUI [1])
alcohol
Item
Have you had any of the following since {insert time from 1 here}? Alcohol, such as beer, wine, or liquor?
boolean
C3176752 (UMLS CUI [1])
alcohol time
Item
If Yes, record date
datetime
C3176754 (UMLS CUI [1])
gum
Item
Have you had any of the following since {insert time from 1 here}? Gum, breath mints, lozenges, or cough drops, or other cough or cold remedies?
boolean
C3176013 (UMLS CUI [1])
gum time
Item
If Yes, record date
datetime
C3176188 (UMLS CUI [1])
antacids
Item
Have you had any of the following since {insert time from 1 here}? Antacids, laxatives, or anti-diarrheals?
boolean
C3176189 (UMLS CUI [1])
anticids time
Item
If Yes, record date
datetime
C3176191 (UMLS CUI [1])
dietary supplements
Item
Have you had any of the following since {insert time from 1 here}? Dietary Supplements such as vitamins and minerals? [Include multivitamins and single nutrient supplements.]
boolean
C3176023 (UMLS CUI [1])
dietary supplements time
Item
If Yes, record date
datetime
C3176025 (UMLS CUI [1])
Item
Are you currently pregnant?
integer
C0032961 (UMLS CUI [1])
pregnancy
Code List
Are you currently pregnant?
CL Item
Yes (1)
C1705108 (UMLS CUI-1)
CL Item
No (2)
C1298908 (UMLS CUI-1)
CL Item
Don't know (3)
C3843613 (UMLS CUI-1)
Item
{Is SP/Are you} now taking insulin?
integer
C3842788 (UMLS CUI [1])
eat or drink
Code List
{Is SP/Are you} now taking insulin?
CL Item
Yes (1)
C1705108 (UMLS CUI-1)
CL Item
No (2)
C1298908 (UMLS CUI-1)
CL Item
Refused (3)
C1705116 (UMLS CUI-1)
CL Item
Don't know (4)
C3843613 (UMLS CUI-1)
Item
{Is SP/Are you} now taking diabetic pills to lower {his/her}/your} blood sugar?
integer
C3176196 (UMLS CUI [1])
eat or drink
Code List
{Is SP/Are you} now taking diabetic pills to lower {his/her}/your} blood sugar?
CL Item
Yes (1)
C1705108 (UMLS CUI-1)
CL Item
No (2)
C1298908 (UMLS CUI-1)
CL Item
Refused (3)
C1705116 (UMLS CUI-1)
CL Item
Don't know (4)
C3843613 (UMLS CUI-1)
Item
Do you have hemophilia?
integer
C0684275 (UMLS CUI [1])
eat or drink
Code List
Do you have hemophilia?
CL Item
Yes (1)
C1705108 (UMLS CUI-1)
CL Item
No (2)
C1298908 (UMLS CUI-1)
CL Item
Refused (3)
C1705116 (UMLS CUI-1)
CL Item
Don't know (4)
C3843613 (UMLS CUI-1)
Item
Have you received cancer chemotherapy in the past four weeks or do you anticipate such therapy in the next four weeks?
integer
C0392920 (UMLS CUI [1])
eat or drink
Code List
Have you received cancer chemotherapy in the past four weeks or do you anticipate such therapy in the next four weeks?
CL Item
Yes (1)
C1705108 (UMLS CUI-1)
CL Item
No (2)
C1298908 (UMLS CUI-1)
CL Item
Refused (3)
C1705116 (UMLS CUI-1)
CL Item
Don't know (4)
C3843613 (UMLS CUI-1)
Item
Exclusion Criteria
integer
C0680251 (UMLS CUI [1])
exclusion criteria
Code List
Exclusion Criteria
CL Item
Hemophilia (1)
C0684275 (UMLS CUI-1)
CL Item
Received cancer chemotherapy in the last 3 weeks (2)
C3842787 (UMLS CUI-1)
CL Item
None – proceed with blood draw (3)
C3842785 (UMLS CUI-1)
service comment
Item
Service comment: Record any comments about the blood draw, including any reasons for the tube not being drawn according to the protocol.
text
C0485795 (UMLS CUI [1])
service comment
Item
Service comment: Record any comments about the blood draw, including any reasons for the tube not being drawn according to the protocol.
text
C0485795 (UMLS CUI [1])
body weight
Item
Body weight
float
C0005910 (UMLS CUI [1])
amount of dextrose solution
Item
Record the amount of dextrose solution administered
float
C1165603 (UMLS CUI [1])
Item
Record the amount of dextrose solution the participant drank
integer
C3176775 (UMLS CUI [1])
amount of dextrose solution the participant drank
Code List
Record the amount of dextrose solution the participant drank
CL Item
All (1)
C0023449 (UMLS CUI-1)
CL Item
Some (2)
C0205392 (UMLS CUI-1)
CL Item
None (3)
C0549184 (UMLS CUI-1)
Item
Record whether all of the solution was consumed in 10 minutes
integer
C3176777 (UMLS CUI [1])
all of the solution was consumed in 10 minutes
Code List
Record whether all of the solution was consumed in 10 minutes
CL Item
Yes – solution consumed in 10 minutes (1)
C3842779 (UMLS CUI-1)
CL Item
No – solution not consumed in 10 minutes (2)
C3842778 (UMLS CUI-1)
minutes elapsed administering the second blood draw
Item
Record the number of minutes elapsed between consuming dextrose solution and administering the second blood draw
float
C3176778 (UMLS CUI [1])
make of equipment used
Item
Make of the equipment used to perform...
text
C3176779 (UMLS CUI [1])
manufacturer of equipment used
Item
Manufacturer of the equipment used to perform...
text
C3176781 (UMLS CUI [1])
Item
Blood draw [PhenX]
text
C3176783 (UMLS CUI [1])
blood draw
Code List
Blood draw [PhenX]
CL Item
Blood draw 1 (Blood draw 1)
CL Item
Blood draw 2 (Blood draw 2)
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