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ID

13078

Beskrivning

Randomized Study of Fetal Neurotransplantation for the Treatment of Parkinson's Disease; ODM derived from: https://clinicaltrials.gov/show/NCT00004844

Länk

https://clinicaltrials.gov/show/NCT00004844

Nyckelord

  1. 2016-01-15 2016-01-15 -
Rättsinnehavare

CC BY-NC 3.0

Uppladdad den

15 januari 2016

DOI

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Licens

Creative Commons BY-NC 3.0

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    Eligibility Parkinson Disease NCT00004844

    Eligibility Parkinson Disease NCT00004844

    Criteria
    Beskrivning

    Criteria

    idiopathic parkinson's disease for at least 7 years with rest tremor or bradykinesia and one of the following cardinal signs: rigidity flexed posture loss of postural reflexes freezing (motor blocks)
    Beskrivning

    parkinson's disease

    Datatyp

    boolean

    Alias
    UMLS CUI [1]
    C0030567
    continuing response to levodopa
    Beskrivning

    levodopa

    Datatyp

    boolean

    Alias
    UMLS CUI [1]
    C0023570
    presence of at least one of the following intractable symptoms or signs: intractable disabling fluctuations intractable disabling dyskinesias intractable "on" freezing (i.e., motor blocks that interfere with walking despite being "on"
    Beskrivning

    intractable symptoms

    Datatyp

    boolean

    Alias
    UMLS CUI [1]
    C0205269
    bilateral parkinsonism when "off" (may be asymmetry between right and left sides)
    Beskrivning

    bilateral parkinsonism

    Datatyp

    boolean

    decreased dopa uptake in the striatum
    Beskrivning

    dopa uptake

    Datatyp

    boolean

    Alias
    UMLS CUI [1]
    C0013023
    no prior brain surgery
    Beskrivning

    brain surgery

    Datatyp

    boolean

    Alias
    UMLS CUI [1]
    C0195775
    cardiovascular: no severe cardiopulmonary disease
    Beskrivning

    cardiopulmonary disease

    Datatyp

    boolean

    Alias
    UMLS CUI [1]
    C0009488
    neurologic: no history of strokes no neuroleptics no encephalitis no oculogyric crisis no remission no cerebellar signs no dementia (mini-mental state score no greater than 22) no supranuclear gaze palsy no babinski sign no orthostatic hypotension no hydrocephalus no brain tumor no occlusive cerebrovascular disease
    Beskrivning

    neurologic disorder

    Datatyp

    boolean

    Alias
    UMLS CUI [1]
    C0027765
    pulmonary: absolute standing pressure at least 90/60 mmhg
    Beskrivning

    pulmonary pressure

    Datatyp

    boolean

    Alias
    UMLS CUI [1]
    C0428642
    other: no diabetes mellitus no exposure to toxins no other severe medical disease hamilton depression scale score of less than 20 points
    Beskrivning

    comorbidity

    Datatyp

    boolean

    Alias
    UMLS CUI [1]
    C0009488

    Similar models

    Eligibility Parkinson Disease NCT00004844

    Name
    Typ
    Description | Question | Decode (Coded Value)
    Datatyp
    Alias
    Item Group
    parkinson's disease
    Item
    idiopathic parkinson's disease for at least 7 years with rest tremor or bradykinesia and one of the following cardinal signs: rigidity flexed posture loss of postural reflexes freezing (motor blocks)
    boolean
    C0030567 (UMLS CUI [1])
    levodopa
    Item
    continuing response to levodopa
    boolean
    C0023570 (UMLS CUI [1])
    intractable symptoms
    Item
    presence of at least one of the following intractable symptoms or signs: intractable disabling fluctuations intractable disabling dyskinesias intractable "on" freezing (i.e., motor blocks that interfere with walking despite being "on"
    boolean
    C0205269 (UMLS CUI [1])
    bilateral parkinsonism
    Item
    bilateral parkinsonism when "off" (may be asymmetry between right and left sides)
    boolean
    dopa uptake
    Item
    decreased dopa uptake in the striatum
    boolean
    C0013023 (UMLS CUI [1])
    brain surgery
    Item
    no prior brain surgery
    boolean
    C0195775 (UMLS CUI [1])
    cardiopulmonary disease
    Item
    cardiovascular: no severe cardiopulmonary disease
    boolean
    C0009488 (UMLS CUI [1])
    neurologic disorder
    Item
    neurologic: no history of strokes no neuroleptics no encephalitis no oculogyric crisis no remission no cerebellar signs no dementia (mini-mental state score no greater than 22) no supranuclear gaze palsy no babinski sign no orthostatic hypotension no hydrocephalus no brain tumor no occlusive cerebrovascular disease
    boolean
    C0027765 (UMLS CUI [1])
    pulmonary pressure
    Item
    pulmonary: absolute standing pressure at least 90/60 mmhg
    boolean
    C0428642 (UMLS CUI [1])
    comorbidity
    Item
    other: no diabetes mellitus no exposure to toxins no other severe medical disease hamilton depression scale score of less than 20 points
    boolean
    C0009488 (UMLS CUI [1])

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