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ID

13078

Descrizione

Randomized Study of Fetal Neurotransplantation for the Treatment of Parkinson's Disease; ODM derived from: https://clinicaltrials.gov/show/NCT00004844

collegamento

https://clinicaltrials.gov/show/NCT00004844

Keywords

  1. 15/01/16 15/01/16 -
Titolare del copyright

CC BY-NC 3.0

Caricato su

15 gennaio 2016

DOI

Per favore, per richiedere un accesso.

Licenza

Creative Commons BY-NC 3.0

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    Eligibility Parkinson Disease NCT00004844

    Eligibility Parkinson Disease NCT00004844

    Criteria
    Descrizione

    Criteria

    idiopathic parkinson's disease for at least 7 years with rest tremor or bradykinesia and one of the following cardinal signs: rigidity flexed posture loss of postural reflexes freezing (motor blocks)
    Descrizione

    parkinson's disease

    Tipo di dati

    boolean

    Alias
    UMLS CUI [1]
    C0030567 (Parkinson Disease)
    SNOMED
    49049000
    continuing response to levodopa
    Descrizione

    levodopa

    Tipo di dati

    boolean

    Alias
    UMLS CUI [1]
    C0023570 (levodopa)
    SNOMED
    15383004
    presence of at least one of the following intractable symptoms or signs: intractable disabling fluctuations intractable disabling dyskinesias intractable "on" freezing (i.e., motor blocks that interfere with walking despite being "on"
    Descrizione

    intractable symptoms

    Tipo di dati

    boolean

    Alias
    UMLS CUI [1]
    C0205269 (Unresponsive to Treatment)
    SNOMED
    20646008
    bilateral parkinsonism when "off" (may be asymmetry between right and left sides)
    Descrizione

    bilateral parkinsonism

    Tipo di dati

    boolean

    decreased dopa uptake in the striatum
    Descrizione

    dopa uptake

    Tipo di dati

    boolean

    Alias
    UMLS CUI [1]
    C0013023 (Dopa)
    SNOMED
    65955006
    no prior brain surgery
    Descrizione

    brain surgery

    Tipo di dati

    boolean

    Alias
    UMLS CUI [1]
    C0195775 (Operation on brain)
    SNOMED
    70586009
    cardiovascular: no severe cardiopulmonary disease
    Descrizione

    cardiopulmonary disease

    Tipo di dati

    boolean

    Alias
    UMLS CUI [1]
    C0009488 (Comorbidity)
    neurologic: no history of strokes no neuroleptics no encephalitis no oculogyric crisis no remission no cerebellar signs no dementia (mini-mental state score no greater than 22) no supranuclear gaze palsy no babinski sign no orthostatic hypotension no hydrocephalus no brain tumor no occlusive cerebrovascular disease
    Descrizione

    neurologic disorder

    Tipo di dati

    boolean

    Alias
    UMLS CUI [1]
    C0027765 (nervous system disorder)
    SNOMED
    118940003
    LOINC
    LA10590-0
    pulmonary: absolute standing pressure at least 90/60 mmhg
    Descrizione

    pulmonary pressure

    Tipo di dati

    boolean

    Alias
    UMLS CUI [1]
    C0428642 (Pulmonary artery pressure)
    SNOMED
    250767002
    other: no diabetes mellitus no exposure to toxins no other severe medical disease hamilton depression scale score of less than 20 points
    Descrizione

    comorbidity

    Tipo di dati

    boolean

    Alias
    UMLS CUI [1]
    C0009488 (Comorbidity)

    Similar models

    Eligibility Parkinson Disease NCT00004844

    Name
    genere
    Description | Question | Decode (Coded Value)
    Tipo di dati
    Alias
    Item Group
    parkinson's disease
    Item
    idiopathic parkinson's disease for at least 7 years with rest tremor or bradykinesia and one of the following cardinal signs: rigidity flexed posture loss of postural reflexes freezing (motor blocks)
    boolean
    C0030567 (UMLS CUI [1])
    levodopa
    Item
    continuing response to levodopa
    boolean
    C0023570 (UMLS CUI [1])
    intractable symptoms
    Item
    presence of at least one of the following intractable symptoms or signs: intractable disabling fluctuations intractable disabling dyskinesias intractable "on" freezing (i.e., motor blocks that interfere with walking despite being "on"
    boolean
    C0205269 (UMLS CUI [1])
    bilateral parkinsonism
    Item
    bilateral parkinsonism when "off" (may be asymmetry between right and left sides)
    boolean
    dopa uptake
    Item
    decreased dopa uptake in the striatum
    boolean
    C0013023 (UMLS CUI [1])
    brain surgery
    Item
    no prior brain surgery
    boolean
    C0195775 (UMLS CUI [1])
    cardiopulmonary disease
    Item
    cardiovascular: no severe cardiopulmonary disease
    boolean
    C0009488 (UMLS CUI [1])
    neurologic disorder
    Item
    neurologic: no history of strokes no neuroleptics no encephalitis no oculogyric crisis no remission no cerebellar signs no dementia (mini-mental state score no greater than 22) no supranuclear gaze palsy no babinski sign no orthostatic hypotension no hydrocephalus no brain tumor no occlusive cerebrovascular disease
    boolean
    C0027765 (UMLS CUI [1])
    pulmonary pressure
    Item
    pulmonary: absolute standing pressure at least 90/60 mmhg
    boolean
    C0428642 (UMLS CUI [1])
    comorbidity
    Item
    other: no diabetes mellitus no exposure to toxins no other severe medical disease hamilton depression scale score of less than 20 points
    boolean
    C0009488 (UMLS CUI [1])

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