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dbGaP phs000725 Rare Cancer Tumors Project - pht003882.v2.p1

- 2023-01-06 - 9 Formulär, 1 Item-grupp, 5 Dataelement, 1 Språk
Item-grupp: pht003882
Principal Investigator: David A. Wheeler, PhD, Human Genome Sequencing Center, Baylor College of Medicine, Houston, Texas, USA MeSH: Neoplasms,Brain Neoplasms,Germinoma,Neoplasms, Germ Cell and Embryonal,Endodermal Sinus Tumor,Teratoma,Carcinoma, Embryonal,Choriocarcinoma,Polycythemia Vera,Craniopharyngioma https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs000725 A large proportion of common cancers affecting patients around the world have been selected for comprehensive cancer genome studies. Further efforts will be needed to tackle the remaining tumor types, including the rare forms of cancers. Although rare, these cancers tend to be more aggressive and fast growing with an early recurrence following initial chemotherapy and poor prognosis. Besides, patients diagnosed with rare cancers may have difficulty finding a physician knowledgeable in treating their type of cancer. While sample collection is a major challenge, the integrated genomic analyses would identify novel causative genes in these rare cancers, shed new light on the biology of the rare cancers, as well as guide novel targeted cancer therapies. Through efficient collaboration, the Human Genome Sequencing Center (HGSC) at Baylor College of Medicine (BCM) has collected/is expected to collect 20 different types of rare cancers, 15-30 cases each. Whole-exome sequencing and high-resolution SNP array analysis were/will be performed for all cases and whole-genome sequencing was designed for a selected subset of the cases. *The Rare Cancer Tumors Cohort is utilized in the following dbGaP sub-studies.* To view genotypes, other molecular data, and derived variables collected in this sub-study, please click on the following sub-study below or in the "Sub-studies" section of this top-level study page phs000725 Rare Cancer Tumors Cohort.- phs000754 Intracranial Germ Cell Tumors - phs000861 Craniopharyngioma Tumors - phs000859 Sezary Syndrome Genomic Analysis

pht003885.v2.p1

1 Item-grupp 3 Dataelement

pht003886.v2.p1

1 Item-grupp 5 Dataelement

pht004475.v2.p1

1 Item-grupp 4 Dataelement

pht004476.v2.p1

1 Item-grupp 6 Dataelement

pht004585.v2.p1

1 Item-grupp 5 Dataelement

Eligibility

1 Item-grupp 1 Dataelement

SIOP CNS GCT II Basic data on radiotherapy DRKS00003907 - Basic data on radiotherapy

- 2014-09-19 - 1 Formulär, 9 Item-grupper, 54 Dataelement, 2 Språk
Item-grupper: Show identification of patient, Basic data on radiotherapy, Whole brain, Spinal canal, Ventricles, Boost tumour site, Tumour site only, Boost sites of metastatic disease, Tumour, cumulative dose
SIOP CNS GCT II: Prospective Trial for the Diagnosis and Treatment of Children, Adolescents and Young Adults With Intracranial Germ Cell Tumors. Principal Investigator Gabriele Calaminus, MD. http://clinicaltrials.gov/show/NCT01424839

SIOP CNS GCT II Treatment technique DRKS00003907 - Treatment technique

- 2014-09-19 - 1 Formulär, 6 Item-grupper, 51 Dataelement, 2 Språk
Item-grupper: Show identification of patient, Technique whole brain, Technique spinal axis, Technique ventricular system, Technique boost to tumour bed or TR to Tumour site only, Technique boost to sites of metastatic disease
SIOP CNS GCT II: Prospective Trial for the Diagnosis and Treatment of Children, Adolescents and Young Adults With Intracranial Germ Cell Tumors. Principal Investigator Gabriele Calaminus, MD. http://clinicaltrials.gov/show/NCT01424839

SIOP CNS GCT II DRKS00003907 NCT01424839 - Toxicity during chemotherapy course NCT01424839

- 2015-06-06 - 1 Formulär, 10 Item-grupper, 39 Dataelement, 2 Språk
Item-grupper: Toxicity hematology, Toxicity neurological, Toxicity infection, Toxicity gastrointestinal, Toxicity skin, Toxicity renal, Toxicity Hearing, Toxicity cardiac, Toxicity metabolic/laboratory, Toxicity other
SIOP CNS GCT II: Prospective Trial for the Diagnosis and Treatment of Children, Adolescents and Young Adults With Intracranial Germ Cell Tumors. Principal Investigator Gabriele Calaminus, MD. http://clinicaltrials.gov/show/NCT01424839

SIOP CNS GCT II Toxicity during radiotherapy DRKS00003907 - Toxicity during radiotherapy

- 2014-09-19 - 1 Formulär, 8 Item-grupper, 25 Dataelement, 2 Språk
Item-grupper: Show identification of patient, Toxicity hematology, Toxicity neurological, Toxicity infection, Toxicity gastrointestinal, Toxicity skin, Toxicity other, Further data on radiotherapy toxicity
SIOP CNS GCT II: Prospective Trial for the Diagnosis and Treatment of Children, Adolescents and Young Adults With Intracranial Germ Cell Tumors. Principal Investigator Gabriele Calaminus, MD. http://clinicaltrials.gov/show/NCT01424839

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