ID
45545
Beskrivning
Principal Investigator: David A. Wheeler, PhD, Human Genome Sequencing Center, Baylor College of Medicine, Houston, Texas, USA MeSH: Neoplasms,Brain Neoplasms,Germinoma,Neoplasms, Germ Cell and Embryonal,Endodermal Sinus Tumor,Teratoma,Carcinoma, Embryonal,Choriocarcinoma,Polycythemia Vera,Craniopharyngioma https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs000725 A large proportion of common cancers affecting patients around the world have been selected for comprehensive cancer genome studies. Further efforts will be needed to tackle the remaining tumor types, including the rare forms of cancers. Although rare, these cancers tend to be more aggressive and fast growing with an early recurrence following initial chemotherapy and poor prognosis. Besides, patients diagnosed with rare cancers may have difficulty finding a physician knowledgeable in treating their type of cancer. While sample collection is a major challenge, the integrated genomic analyses would identify novel causative genes in these rare cancers, shed new light on the biology of the rare cancers, as well as guide novel targeted cancer therapies. Through efficient collaboration, the Human Genome Sequencing Center (HGSC) at Baylor College of Medicine (BCM) has collected/is expected to collect 20 different types of rare cancers, 15-30 cases each. Whole-exome sequencing and high-resolution SNP array analysis were/will be performed for all cases and whole-genome sequencing was designed for a selected subset of the cases. *The Rare Cancer Tumors Cohort is utilized in the following dbGaP sub-studies.* To view genotypes, other molecular data, and derived variables collected in this sub-study, please click on the following sub-study below or in the "Sub-studies" section of this top-level study page phs000725 Rare Cancer Tumors Cohort.- phs000754 Intracranial Germ Cell Tumors - phs000861 Craniopharyngioma Tumors - phs000859 Sezary Syndrome Genomic Analysis
Länk
Nyckelord
Versioner (1)
- 2023-01-06 2023-01-06 - Chiara Middel
Rättsinnehavare
David A. Wheeler, PhD, Human Genome Sequencing Center, Baylor College of Medicine, Houston, Texas, USA
Uppladdad den
6 januari 2023
DOI
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Licens
Creative Commons BY 4.0
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dbGaP phs000725 Rare Cancer Tumors Project
Eligibility Criteria
- StudyEvent: SEV1
- Eligibility Criteria
- Subject ID, affection status, consent group, subject source, and source subject ID of participants with or without rare cancer tumors and involved in the "Rare Cancer Tumors Project" project.
- Subject ID, sample ID, sample source, source sample ID, study accession ID, and sample use variable obtained from participants with or without rare cancer tumors and involved in the "Rare Cancer Tumors Project" project.
- Subject ID, age, gender of participants with or without intracranial germ cell tumors and involve in the "Whole-exome Sequencing of Intracranial Germ Cell Tumors performed at Human Genome Sequencing Center, Baylor College of Medicine" project.
- Sample ID, analyte type, body site, and histological type of tumors of participants with or without intracranial germ cell tumors and involve in the "Whole-exome Sequencing of Intracranial Germ Cell Tumors performed at Human Genome Sequencing Center, Baylor College of Medicine" project.
- Subject ID, age, gender, and race of participants with or without craniopharyngioma tumors and involved in the "Whole Exome Sequencing of Craniopharyngioma Tumors at Human Genome Sequencing Center, Baylor College of Medicine" project.
- Sample ID, analyte type, body site where sample was obtained, sequencing center, tumor specimen, and tumor status of sample of participants with or without craniopharyngioma tumors and involved in the "Whole Exome Sequencing of Craniopharyngioma Tumors at Human Genome Sequencing Center, Baylor College of Medicine" project.
- Subject ID, gender, diagnosis age, race, and study stage of participants with or without Sezary Syndrome and involved in the "Integrated Genomic Analysis of Sezary Syndrome at the Human Genome Sequencing Center, Baylor College of Medicine" project.
- Sample ID, analyte type, body site where sample was obtained, sequences center, and tumor status of sample obtained from participants with or without Sezary Syndrome and involved in the "Integrated Genomic Analysis of Sezary Syndrome at the Human Genome Sequencing Center, Baylor College of Medicine" project.
Similar models
Eligibility Criteria
- StudyEvent: SEV1
- Eligibility Criteria
- Subject ID, affection status, consent group, subject source, and source subject ID of participants with or without rare cancer tumors and involved in the "Rare Cancer Tumors Project" project.
- Subject ID, sample ID, sample source, source sample ID, study accession ID, and sample use variable obtained from participants with or without rare cancer tumors and involved in the "Rare Cancer Tumors Project" project.
- Subject ID, age, gender of participants with or without intracranial germ cell tumors and involve in the "Whole-exome Sequencing of Intracranial Germ Cell Tumors performed at Human Genome Sequencing Center, Baylor College of Medicine" project.
- Sample ID, analyte type, body site, and histological type of tumors of participants with or without intracranial germ cell tumors and involve in the "Whole-exome Sequencing of Intracranial Germ Cell Tumors performed at Human Genome Sequencing Center, Baylor College of Medicine" project.
- Subject ID, age, gender, and race of participants with or without craniopharyngioma tumors and involved in the "Whole Exome Sequencing of Craniopharyngioma Tumors at Human Genome Sequencing Center, Baylor College of Medicine" project.
- Sample ID, analyte type, body site where sample was obtained, sequencing center, tumor specimen, and tumor status of sample of participants with or without craniopharyngioma tumors and involved in the "Whole Exome Sequencing of Craniopharyngioma Tumors at Human Genome Sequencing Center, Baylor College of Medicine" project.
- Subject ID, gender, diagnosis age, race, and study stage of participants with or without Sezary Syndrome and involved in the "Integrated Genomic Analysis of Sezary Syndrome at the Human Genome Sequencing Center, Baylor College of Medicine" project.
- Sample ID, analyte type, body site where sample was obtained, sequences center, and tumor status of sample obtained from participants with or without Sezary Syndrome and involved in the "Integrated Genomic Analysis of Sezary Syndrome at the Human Genome Sequencing Center, Baylor College of Medicine" project.
C0680251 (UMLS CUI [1,2])
C0205469 (UMLS CUI [1,2])
C0011900 (UMLS CUI [1,3])
C1512693 (UMLS CUI [2,1])
C0205170 (UMLS CUI [2,2])
C0012854 (UMLS CUI [2,3])
C0332306 (UMLS CUI [2,4])
C1265611 (UMLS CUI [2,5])