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6 Zoekresultaten.

Eligibility Metastases of Central Nervous System NCT00831545

- 24-01-16 - 1 Formulier, 2 Itemgroepen, 19 Data-elementen, 1 Taal

Itemgroepen: Inclusion Criteria, Exclusion Criteria

Study to Evaluate the Efficacy and Safety of Temozolomide in Subjects With Brain Metastases of Either Malignant Melanoma, Breast, or Non-small Cell Lung Cancer (P02064); ODM derived from: https://clinicaltrials.gov/show/NCT00831545

dbGaP phs000907 Brain Metastases in Squamous Cell Lung Cancers - Eligibility

- 06-04-24 - 5 Formulieren, 1 Itemgroep, 1 Data-element, 1 Taal

Itemgroep: IG.elig

Principal Investigator: Paul K. Paik, MD, Memorial Sloan Kettering Cancer Center, New York, NY, USA MeSH: Squamous Cell Carcinoma,Nonsmall Cell Lung Cancer https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs000907 Putative oncogenic pathways in squamous cell lung cancer have been recently characterized, although their biologic repercussions in patients is largely unknown. This study sought to discover potential clinical manifestations of major pathways in squamous cell lung cancer, particularly the PI3K pathway. Two key findings emerged: patients with stage IV squamous cell lung cancer whose tumors harbored upstream PI3K aberrations had significantly worse survival and a higher burden of metastatic disease. In addition, brain metastases were significantly more common in these patients than in others. Paired lung primary/brain metastasis genotyping, including RNA sequencing and whole exome sequencing, uncovered a high degree of genetic heterogeneity between lung/brain pairs, and identified potential regulators of the metastatic process to brain.

pht004695.v1.p1

1 Itemgroep 5 Data-elementen

pht004696.v1.p1

1 Itemgroep 5 Data-elementen

pht004697.v1.p1

1 Itemgroep 6 Data-elementen

pht004698.v1.p1

1 Itemgroep 12 Data-elementen

Lung Cancer NCT00096265 Demographic - A5 RTOG Phase III - Multiple Brain Mets Demographic Data Form - version 2 - 2277657v3.0 - A5 RTOG Phase III - Multiple Brain Mets Demographic Data Form - version 2

- 09-01-15 - 1 Formulier, 4 Itemgroepen, 41 Data-elementen, 1 Taal

Itemgroepen: Header, Module 1, Module 2, Family History

A5 RTOG Phase III - Multiple Brain Mets Demographic Data Form - version 2 Radiation Therapy and Stereotactic Radiosurgery With or Without Temozolomide or Erlotinib in Treating Patients With Brain Metastases Secondary to Non-Small Cell Lung Cancer Source Form: NCI FormBuilder: https://formbuilder.nci.nih.gov/FormBuilder/formDetailsAction.do?method=getFormDetails&formIdSeq=D81B5AB0-2D5B-616A-E034-0003BA12F5E7

Eligibility Chemotherapeutic Agent Toxicity NCT01097317

- 27-11-17 - 1 Formulier, 1 Itemgroep, 12 Data-elementen, 1 Taal

Itemgroep: Criteria

First-Line Chemotherapy With or Without Neuromuscular Electrical Stimulation in Treating Patients With Non-Small Cell Lung Cancer; ODM derived from: https://clinicaltrials.gov/show/NCT01097317

Eligibility Carcinoma, Non-Small-Cell Lung NCT00637624

- 14-11-17 - 1 Formulier, 2 Itemgroepen, 11 Data-elementen, 1 Taal

Itemgroepen: Inclusion Criteria, Exclusion Criteria

N-AcetylCysteine vs. Placebo to Prevent Neurotoxicity Induced by Platinum Containing Chemotherapy; ODM derived from: https://clinicaltrials.gov/show/NCT00637624

E5508 On-Study Form NCT01107626

- 20-09-21 - 1 Formulier, 13 Itemgroepen, 75 Data-elementen, 1 Taal

Itemgroepen: Header Module, Patient demographics, Data amendment, Pre-Treatment Characteristics, Pre-Treatment Characteristics1, Advanced NSCLC Disease Description, Metastatic Site, Medical History, Pre-Registration Hematology/Chemistry, Advanced NSCLC Prior Treatment, NSCLC Brain Metastases, Baseline Abnormalities, Comments

E5508 On-Study Form NCT01107626 Bevacizumab or Pemetrexed Disodium Alone or In Combination After Induction Therapy in Treating Patients With Advanced Non-Squamous Non-Small Cell Lung Cancer Source Form: NCI FormBuilder: https://formbuilder.nci.nih.gov/FormBuilder/formDetailsAction.do?method=getFormDetails&formIdSeq=6D435D37-5591-AA13-E040-BB89AD43538D

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