ID

45875

Description

Principal Investigator: Lynne Wagenknecht, Wake Forest University School of Medicine, University of North Carolina, Winston-Salem, NC, USA MeSH: Insulin Resistance https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs001008 TThe IRAS Family Study was a family study designed to examine the genetic and epidemiologic basis of glucose homeostasis traits and abdominal adiposity. Briefly, self-reported Mexican pedigrees were recruited in San Antonio, TX and San Luis Valley, CO. Probands with large families were recruited from the initial non-family-based IRAS Study, which was modestly enriched for impaired glucose tolerance and T2D. GUARDIAN includes 1,024 individuals in 88 pedigrees from the IRAS Family Study. Insulin sensitivity was obtained by FSIGT.

Link

dbGaP study = phs001008

Keywords

  1. 10/31/23 10/31/23 - Simon Heim
Copyright Holder

Lynne Wagenknecht, Wake Forest University School of Medicine, University of North Carolina, Winston-Salem, NC, USA

Uploaded on

October 31, 2023

DOI

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License

Creative Commons BY 4.0

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dbGaP phs001008 GUARDIAN: IRAS FAMILY STUDY (IRASFS)

The dataset provides insulin sensitivity and metabolic clearance values, BMI measurements and sociodemographic information (i.e. age/gender) of participants.

pht005110
Description

pht005110

Alias
UMLS CUI [1,1]
C3846158
Famiy ID
Description

FAMILY_ID

Data type

text

Alias
UMLS CUI [1,1]
C3669174
Subject ID
Description

SUBJECT_ID

Data type

text

Alias
UMLS CUI [1,1]
C2348585
Sex
Description

SEX

Data type

text

Alias
UMLS CUI [1,1]
C0079399
Age (years)
Description

Age

Data type

text

Measurement units
  • Years
Alias
UMLS CUI [1,1]
C0001779
Years
Body Mass Index (Kg/M^2)
Description

BMI

Data type

text

Measurement units
  • kg/m2
Alias
UMLS CUI [1,1]
C1305855
kg/m2
Center
Description

Center

Data type

text

Alias
UMLS CUI [1,1]
C1301943
UMLS CUI [1,2]
C0600091
Insulin Sensitivity Index (x.0001/min/mIU/1ml-1)
Description

SI

Data type

text

Alias
UMLS CUI [1,1]
C5212332
Metabolic Clearance Rate of Insulin (L/min)
Description

MCRI

Data type

text

Measurement units
  • L/min
Alias
UMLS CUI [1,1]
C0025515
UMLS CUI [1,2]
C0021641
L/min
Participant's ethnicity
Description

ETHNICITY

Data type

string

Alias
UMLS CUI [1,1]
C5441552

Similar models

The dataset provides insulin sensitivity and metabolic clearance values, BMI measurements and sociodemographic information (i.e. age/gender) of participants.

Name
Type
Description | Question | Decode (Coded Value)
Data type
Alias
Item Group
pht005110
C3846158 (UMLS CUI [1,1])
FAMILY_ID
Item
Famiy ID
text
C3669174 (UMLS CUI [1,1])
SUBJECT_ID
Item
Subject ID
text
C2348585 (UMLS CUI [1,1])
Item
Sex
text
C0079399 (UMLS CUI [1,1])
Code List
Sex
CL Item
Male (1)
C0086582 (UMLS CUI [1,1])
CL Item
Female (2)
C0086287 (UMLS CUI [1,1])
Age
Item
Age (years)
text
C0001779 (UMLS CUI [1,1])
BMI
Item
Body Mass Index (Kg/M^2)
text
C1305855 (UMLS CUI [1,1])
Item
Center
text
C1301943 (UMLS CUI [1,1])
C0600091 (UMLS CUI [1,2])
Code List
Center
CL Item
San Luis Valley (0)
CL Item
San Antonio (1)
SI
Item
Insulin Sensitivity Index (x.0001/min/mIU/1ml-1)
text
C5212332 (UMLS CUI [1,1])
MCRI
Item
Metabolic Clearance Rate of Insulin (L/min)
text
C0025515 (UMLS CUI [1,1])
C0021641 (UMLS CUI [1,2])
ETHNICITY
Item
Participant's ethnicity
string
C5441552 (UMLS CUI [1,1])

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