ID

45868

Beschrijving

Principal Investigator: Donald W. Bowden, Wake Forest School of Medicine, Winston-Salem, NC, USA MeSH: Cardiovascular Diseases,Vascular Calcification,Diabetes Mellitus https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs001012 The Diabetes Heart Study is a family based study enriched for type 2 diabetes (T2D). The cohort included 1220 self-reported European Americans from 475 families (Bowden et al 2010 Review of Diabetic Studies 7:188-201: PMID: 21409311; Bowden et al 2008 Annals of Human Genetics 72:598-601 PMID: 18460048) and included siblings concordant for T2D; where possible unaffected siblings were also recruited. The cohort was recruited between 1998 and 2006. Participants were extensively phenotyped for measures of subclinical CVD and other known CVD risk factors. Primary outcomes were quantified burden of vascular calcified plaque in the coronary artery, carotid artery and abdominal aorta all determined from non-contrast computed tomography scans.

Link

dbGaP study = phs001012

Trefwoorden

Versies (1)
  1. 26-10-23 26-10-23 - Simon Heim
Houder van rechten

Donald W. Bowden, Wake Forest School of Medicine, Winston-Salem, NC, USA

Geüploaded op

26 oktober 2023

DOI

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Licentie

Creative Commons BY 4.0
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dbGaP phs001012 The Diabetes Heart Study (DHS)

Engels

The dataset includes diagnosis information of participants (Type 2 diabetes), blood test results for high and low density lipoproteins, triglycerides, and C-reactive protein, BMI values, IMT thickness and extent of calcified carotid plaques.

6 Formulieren  
pht005550
Beschrijving

pht005550

Alias
UMLS CUI [1,1]
C3846158
De-identified Subject ID
Beschrijving

SUBJECT_ID

Datatype

string

Alias
UMLS CUI [1,1]
C4684638
UMLS CUI [1,2]
C2348585
Age at recruitment
Beschrijving

age

Datatype

text

Maateenheden
  • Years
Alias
UMLS CUI [1,1]
C0001779
UMLS CUI [1,2]
C2985691
Years
Gender of participant
Beschrijving

gender

Datatype

text

Alias
UMLS CUI [1,1]
C0079399
Type 2 diabetes affected
Beschrijving

t2dm_affected

Datatype

text

Alias
UMLS CUI [1,1]
C4014362
First admixture proportion
Beschrijving

admix1

Datatype

float

Alias
UMLS CUI [1,1]
C1510816
UMLS CUI [1,2]
C1709707
UMLS CUI [1,3]
C0205435
Secondary admixture proportion
Beschrijving

admix2

Datatype

float

Alias
UMLS CUI [1,1]
C1510816
UMLS CUI [1,2]
C1709707
UMLS CUI [1,3]
C0205436
Coronary artery calcified plaque
Beschrijving

avecac

Datatype

float

Alias
UMLS CUI [1,1]
C4697970
UMLS CUI [1,2]
C0205042
Carotid artery calcified plaque (130)
Beschrijving

avecarotid

Datatype

float

Alias
UMLS CUI [1,1]
C4697970
UMLS CUI [1,2]
C0007272
Abdominal aortic calcified plaque
Beschrijving

aorta

Datatype

float

Alias
UMLS CUI [1,1]
C4697970
UMLS CUI [1,2]
C0003484
Aortic intima-media thickness
Beschrijving

imt

Datatype

float

Maateenheden
  • mm
Alias
UMLS CUI [1,1]
C1960467
UMLS CUI [1,2]
C0003483
mm
Body mass index
Beschrijving

bmi

Datatype

float

Maateenheden
  • kg/m2
Alias
UMLS CUI [1,1]
C1305855
kg/m2
Triglycerides
Beschrijving

trig

Datatype

float

Maateenheden
  • mg/dl
Alias
UMLS CUI [1,1]
C0202236
mg/dl
High density lipoprotein
Beschrijving

hdl

Datatype

float

Maateenheden
  • mg/dl
Alias
UMLS CUI [1,1]
C0392885
mg/dl
Low density lipoprotein
Beschrijving

ldl

Datatype

float

Maateenheden
  • mg/dl
Alias
UMLS CUI [1,1]
C0202117
mg/dl
C-reactive protein
Beschrijving

crp

Datatype

float

Maateenheden
  • mg/dl
Alias
UMLS CUI [1,1]
C0006560
mg/dl
Total cholesterol
Beschrijving

chol

Datatype

float

Maateenheden
  • mg/dl
Alias
UMLS CUI [1,1]
C1445957
mg/dl
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Similar models

The dataset includes diagnosis information of participants (Type 2 diabetes), blood test results for high and low density lipoproteins, triglycerides, and C-reactive protein, BMI values, IMT thickness and extent of calcified carotid plaques.

6 Formulieren
Name
Type
Description | Question | Decode (Coded Value)
Datatype
Alias
Item Group
pht005550
C3846158 (UMLS CUI [1,1])
SUBJECT_ID
Item
De-identified Subject ID
string
C4684638 (UMLS CUI [1,1])
C2348585 (UMLS CUI [1,2])
age
Item
Age at recruitment
text
C0001779 (UMLS CUI [1,1])
C2985691 (UMLS CUI [1,2])
Item
Gender of participant
text
C0079399 (UMLS CUI [1,1])
gender
Code List
Gender of participant
CL Item
Male (0)
C0086582 (UMLS CUI [1,1])
CL Item
Female (1)
C0086287 (UMLS CUI [1,1])
CL Item
Missing (NA)
Item
Type 2 diabetes affected
text
C4014362 (UMLS CUI [1,1])
t2dm_affected
Code List
Type 2 diabetes affected
CL Item
Not affected (0)
CL Item
Affected (1)
C3274647 (UMLS CUI [1,1])
CL Item
Missing (NA)
admix1
Item
First admixture proportion
float
C1510816 (UMLS CUI [1,1])
C1709707 (UMLS CUI [1,2])
C0205435 (UMLS CUI [1,3])
admix2
Item
Secondary admixture proportion
float
C1510816 (UMLS CUI [1,1])
C1709707 (UMLS CUI [1,2])
C0205436 (UMLS CUI [1,3])
avecac
Item
Coronary artery calcified plaque
float
C4697970 (UMLS CUI [1,1])
C0205042 (UMLS CUI [1,2])
avecarotid
Item
Carotid artery calcified plaque (130)
float
C4697970 (UMLS CUI [1,1])
C0007272 (UMLS CUI [1,2])
aorta
Item
Abdominal aortic calcified plaque
float
C4697970 (UMLS CUI [1,1])
C0003484 (UMLS CUI [1,2])
imt
Item
Aortic intima-media thickness
float
C1960467 (UMLS CUI [1,1])
C0003483 (UMLS CUI [1,2])
bmi
Item
Body mass index
float
C1305855 (UMLS CUI [1,1])
trig
Item
Triglycerides
float
C0202236 (UMLS CUI [1,1])
hdl
Item
High density lipoprotein
float
C0392885 (UMLS CUI [1,1])
ldl
Item
Low density lipoprotein
float
C0202117 (UMLS CUI [1,1])
crp
Item
C-reactive protein
float
C0006560 (UMLS CUI [1,1])
chol
Item
Total cholesterol
float
C1445957 (UMLS CUI [1,1])
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