ID

45868

Beschreibung

Principal Investigator: Donald W. Bowden, Wake Forest School of Medicine, Winston-Salem, NC, USA MeSH: Cardiovascular Diseases,Vascular Calcification,Diabetes Mellitus https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs001012 The Diabetes Heart Study is a family based study enriched for type 2 diabetes (T2D). The cohort included 1220 self-reported European Americans from 475 families (Bowden et al 2010 Review of Diabetic Studies 7:188-201: PMID: 21409311; Bowden et al 2008 Annals of Human Genetics 72:598-601 PMID: 18460048) and included siblings concordant for T2D; where possible unaffected siblings were also recruited. The cohort was recruited between 1998 and 2006. Participants were extensively phenotyped for measures of subclinical CVD and other known CVD risk factors. Primary outcomes were quantified burden of vascular calcified plaque in the coronary artery, carotid artery and abdominal aorta all determined from non-contrast computed tomography scans.

Link

dbGaP study = phs001012

Stichworte

Versionen (1)
  1. 26/10/23 26/10/23 - Simon Heim
Rechteinhaber

Donald W. Bowden, Wake Forest School of Medicine, Winston-Salem, NC, USA

Hochgeladen am

26 ottobre 2023

DOI

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Lizenz

Creative Commons BY 4.0
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dbGaP phs001012 The Diabetes Heart Study (DHS)

Englisch

The dataset includes diagnosis information of participants (Type 2 diabetes), blood test results for high and low density lipoproteins, triglycerides, and C-reactive protein, BMI values, IMT thickness and extent of calcified carotid plaques.

6 Formulare  
pht005550
Beschreibung

pht005550

Alias
UMLS CUI [1,1]
C3846158
De-identified Subject ID
Beschreibung

SUBJECT_ID

Datentyp

string

Alias
UMLS CUI [1,1]
C4684638
UMLS CUI [1,2]
C2348585
Age at recruitment
Beschreibung

age

Datentyp

text

Maßeinheiten
  • Years
Alias
UMLS CUI [1,1]
C0001779
UMLS CUI [1,2]
C2985691
Years
Gender of participant
Beschreibung

gender

Datentyp

text

Alias
UMLS CUI [1,1]
C0079399
Type 2 diabetes affected
Beschreibung

t2dm_affected

Datentyp

text

Alias
UMLS CUI [1,1]
C4014362
First admixture proportion
Beschreibung

admix1

Datentyp

float

Alias
UMLS CUI [1,1]
C1510816
UMLS CUI [1,2]
C1709707
UMLS CUI [1,3]
C0205435
Secondary admixture proportion
Beschreibung

admix2

Datentyp

float

Alias
UMLS CUI [1,1]
C1510816
UMLS CUI [1,2]
C1709707
UMLS CUI [1,3]
C0205436
Coronary artery calcified plaque
Beschreibung

avecac

Datentyp

float

Alias
UMLS CUI [1,1]
C4697970
UMLS CUI [1,2]
C0205042
Carotid artery calcified plaque (130)
Beschreibung

avecarotid

Datentyp

float

Alias
UMLS CUI [1,1]
C4697970
UMLS CUI [1,2]
C0007272
Abdominal aortic calcified plaque
Beschreibung

aorta

Datentyp

float

Alias
UMLS CUI [1,1]
C4697970
UMLS CUI [1,2]
C0003484
Aortic intima-media thickness
Beschreibung

imt

Datentyp

float

Maßeinheiten
  • mm
Alias
UMLS CUI [1,1]
C1960467
UMLS CUI [1,2]
C0003483
mm
Body mass index
Beschreibung

bmi

Datentyp

float

Maßeinheiten
  • kg/m2
Alias
UMLS CUI [1,1]
C1305855
kg/m2
Triglycerides
Beschreibung

trig

Datentyp

float

Maßeinheiten
  • mg/dl
Alias
UMLS CUI [1,1]
C0202236
mg/dl
High density lipoprotein
Beschreibung

hdl

Datentyp

float

Maßeinheiten
  • mg/dl
Alias
UMLS CUI [1,1]
C0392885
mg/dl
Low density lipoprotein
Beschreibung

ldl

Datentyp

float

Maßeinheiten
  • mg/dl
Alias
UMLS CUI [1,1]
C0202117
mg/dl
C-reactive protein
Beschreibung

crp

Datentyp

float

Maßeinheiten
  • mg/dl
Alias
UMLS CUI [1,1]
C0006560
mg/dl
Total cholesterol
Beschreibung

chol

Datentyp

float

Maßeinheiten
  • mg/dl
Alias
UMLS CUI [1,1]
C1445957
mg/dl
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Ähnliche Modelle

The dataset includes diagnosis information of participants (Type 2 diabetes), blood test results for high and low density lipoproteins, triglycerides, and C-reactive protein, BMI values, IMT thickness and extent of calcified carotid plaques.

6 Formulare
Name
Typ
Description | Question | Decode (Coded Value)
Datentyp
Alias
Item Group
pht005550
C3846158 (UMLS CUI [1,1])
SUBJECT_ID
Item
De-identified Subject ID
string
C4684638 (UMLS CUI [1,1])
C2348585 (UMLS CUI [1,2])
age
Item
Age at recruitment
text
C0001779 (UMLS CUI [1,1])
C2985691 (UMLS CUI [1,2])
Item
Gender of participant
text
C0079399 (UMLS CUI [1,1])
gender
Code List
Gender of participant
CL Item
Male (0)
C0086582 (UMLS CUI [1,1])
CL Item
Female (1)
C0086287 (UMLS CUI [1,1])
CL Item
Missing (NA)
Item
Type 2 diabetes affected
text
C4014362 (UMLS CUI [1,1])
t2dm_affected
Code List
Type 2 diabetes affected
CL Item
Not affected (0)
CL Item
Affected (1)
C3274647 (UMLS CUI [1,1])
CL Item
Missing (NA)
admix1
Item
First admixture proportion
float
C1510816 (UMLS CUI [1,1])
C1709707 (UMLS CUI [1,2])
C0205435 (UMLS CUI [1,3])
admix2
Item
Secondary admixture proportion
float
C1510816 (UMLS CUI [1,1])
C1709707 (UMLS CUI [1,2])
C0205436 (UMLS CUI [1,3])
avecac
Item
Coronary artery calcified plaque
float
C4697970 (UMLS CUI [1,1])
C0205042 (UMLS CUI [1,2])
avecarotid
Item
Carotid artery calcified plaque (130)
float
C4697970 (UMLS CUI [1,1])
C0007272 (UMLS CUI [1,2])
aorta
Item
Abdominal aortic calcified plaque
float
C4697970 (UMLS CUI [1,1])
C0003484 (UMLS CUI [1,2])
imt
Item
Aortic intima-media thickness
float
C1960467 (UMLS CUI [1,1])
C0003483 (UMLS CUI [1,2])
bmi
Item
Body mass index
float
C1305855 (UMLS CUI [1,1])
trig
Item
Triglycerides
float
C0202236 (UMLS CUI [1,1])
hdl
Item
High density lipoprotein
float
C0392885 (UMLS CUI [1,1])
ldl
Item
Low density lipoprotein
float
C0202117 (UMLS CUI [1,1])
crp
Item
C-reactive protein
float
C0006560 (UMLS CUI [1,1])
chol
Item
Total cholesterol
float
C1445957 (UMLS CUI [1,1])
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