ID
45868
Beschrijving
Principal Investigator: Donald W. Bowden, Wake Forest School of Medicine, Winston-Salem, NC, USA MeSH: Cardiovascular Diseases,Vascular Calcification,Diabetes Mellitus https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs001012 The Diabetes Heart Study is a family based study enriched for type 2 diabetes (T2D). The cohort included 1220 self-reported European Americans from 475 families (Bowden et al 2010 Review of Diabetic Studies 7:188-201: PMID: 21409311; Bowden et al 2008 Annals of Human Genetics 72:598-601 PMID: 18460048) and included siblings concordant for T2D; where possible unaffected siblings were also recruited. The cohort was recruited between 1998 and 2006. Participants were extensively phenotyped for measures of subclinical CVD and other known CVD risk factors. Primary outcomes were quantified burden of vascular calcified plaque in the coronary artery, carotid artery and abdominal aorta all determined from non-contrast computed tomography scans.
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- 26-10-23 26-10-23 - Simon Heim
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Donald W. Bowden, Wake Forest School of Medicine, Winston-Salem, NC, USA
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26 oktober 2023
DOI
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Creative Commons BY 4.0
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dbGaP phs001012 The Diabetes Heart Study (DHS)
Pedigree Information
- StudyEvent: SEV1
- Eligibility Criteria
- Subject - Consent Information
- Pedigree Information
- Subject - Sample Mapping - Sample Use Information
- The dataset includes diagnosis information of participants (Type 2 diabetes), blood test results for high and low density lipoproteins, triglycerides, and C-reactive protein, BMI values, IMT thickness and extent of calcified carotid plaques.
- Sample - Attribute Information
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Pedigree Information
- StudyEvent: SEV1
- Eligibility Criteria
- Subject - Consent Information
- Pedigree Information
- Subject - Sample Mapping - Sample Use Information
- The dataset includes diagnosis information of participants (Type 2 diabetes), blood test results for high and low density lipoproteins, triglycerides, and C-reactive protein, BMI values, IMT thickness and extent of calcified carotid plaques.
- Sample - Attribute Information
C0030761 (UMLS CUI [1,2])
C0030761 (UMLS CUI [1,2])
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