ID
45842
Beschrijving
Principal Investigator: Steven McCarroll, PhD, The Broad Institute of MIT and Harvard, Cambridge, MA, USA MeSH: Schizophrenia,Bipolar Disorder https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs001020 The Center for Genomic Psychiatry at the University of Southern California (USC), SUNY Downstate and an extensive network of academic medical centers have created the Genomic Psychiatry Cohort (GPC). The GPC consists of a large clinical cohort of patients with schizophrenia, bipolar disorder, and healthy controls. The data generation of genotyping and whole genome sequencing of the GPC has been done in collaboration with the USC and the Broad Institute of MIT and Harvard. Genome-wide association studies are being performed with the samples to identify genetic risks for psychiatric disease. Genotyping is also being used to determine ancestry informative markers and replication of candidate genes. Whole genome sequencing identifies functional variants associated with disease risk.
Link
https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs001020
Trefwoorden
Versies (1)
- 24-08-23 24-08-23 - Arman Ghanaat
Houder van rechten
Steven McCarroll, PhD, The Broad Institute of MIT and Harvard, Cambridge, MA, USA
Geüploaded op
24 augustus 2023
DOI
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Licentie
Creative Commons BY 4.0
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dbGaP phs001020 Genomic Psychiatry Cohort (GPC) Whole Genome Sequencing and Genotyping Study
Eligibility Criteria
- StudyEvent: SEV1
- Eligibility Criteria
- This subject consent data table contains subject IDs and consent group information.
- This subject sample mapping data table includes a mapping of study subject IDs to sample IDs. Samples are the final preps submitted for genotyping, sequencing, and/or expression data. For example, if one patient (subject ID) gave one sample, and that sample was processed differently to generate 2 sequencing runs, there would be two rows, both using the same subject ID, but having 2 unique sample IDs.
- This subject phenotype table informs of subject's sex, primary disease, case-control status for schizophrenia or bipolar disorder, and genetically determined ancestry.
- This sample attributes table informs of body site where sample was collected, sample analyte type, sample tumor status, sample histology, whether 30X mean coverage was achieved in the sample during sequencing, and site where sequencing took place.
Similar models
Eligibility Criteria
- StudyEvent: SEV1
- Eligibility Criteria
- This subject consent data table contains subject IDs and consent group information.
- This subject sample mapping data table includes a mapping of study subject IDs to sample IDs. Samples are the final preps submitted for genotyping, sequencing, and/or expression data. For example, if one patient (subject ID) gave one sample, and that sample was processed differently to generate 2 sequencing runs, there would be two rows, both using the same subject ID, but having 2 unique sample IDs.
- This subject phenotype table informs of subject's sex, primary disease, case-control status for schizophrenia or bipolar disorder, and genetically determined ancestry.
- This sample attributes table informs of body site where sample was collected, sample analyte type, sample tumor status, sample histology, whether 30X mean coverage was achieved in the sample during sequencing, and site where sequencing took place.
C0680251 (UMLS CUI [1,2])
C0041703 (UMLS CUI [1,2])
C1518602 (UMLS CUI [1,3])
C0205394 (UMLS CUI [1,4])
C0449604 (UMLS CUI [1,5])
C0001779 (UMLS CUI [2,1])
C0439091 (UMLS CUI [2,2])
C3715206 (UMLS CUI [2,3])
C5444992 (UMLS CUI [3,1])
C0036341 (UMLS CUI [3,2])
C1515981 (UMLS CUI [3,3])
C0205392 (UMLS CUI [3,4])
C0005586 (UMLS CUI [3,5])
C0009932 (UMLS CUI [4,1])
C0445247 (UMLS CUI [4,2])
C0017446 (UMLS CUI [4,3])