0 Bedömningar

ID

45766

Beskrivning

Principal Investigator: Jerry L. Nadler, Eastern Virginia Medical School, Norfolk, VA, USA MeSH: Diabetes Mellitus, Type 2,Diabetes Complications https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs001130 The NIDDM-Atherosclerosis Study, funded by NHLBI, was designed as a family study to examine the genetic basis of subclinical atherosclerosis and diabetes in Hispanic families. Family members of probands with T2D were recruited in the Los Angeles area. The baseline examination of the cohort included the euglycemic hyperinsulinemic clamp test from which the two key phenotypes were obtained: insulin sensitivity (M) and metabolic clearance rate of insulin (MCRI). Genome-wide genotyping was obtained under separate funding by NIDDK as a part of the GUARDIAN (Genetics Underlying Diabetes in Hispanics) Consortium.

Länk

dbGaP-study=phs001130

Nyckelord

  1. 2023-06-16 2023-06-16 - Chiara Middel
Rättsinnehavare

Jerry L. Nadler, Eastern Virginia Medical School, Norfolk, VA, USA

Uppladdad den

16 juni 2023

DOI

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Licens

Creative Commons BY 4.0

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    dbGaP phs001130 NIDDM-Atherosclerosis Study (NIDDM-Athero)

    The dataset provides onformation of metabolic clearance rate of insulin, insulin sensitivity, BMI measurements, and presence/absence of coronary artery disease, in addition to basic socio-demographic information.

    pht008418
    Beskrivning

    pht008418

    Alias
    UMLS CUI [1,1]
    C3846158
    De-identified Subject ID
    Beskrivning

    Collected in Exam 1

    Datatyp

    string

    Alias
    UMLS CUI [1,1]
    C4684638
    UMLS CUI [1,2]
    C2348585
    Subject age
    Beskrivning

    Collected in Exam 1

    Datatyp

    float

    Måttenheter
    • Years
    Alias
    UMLS CUI [1,1]
    C0001779
    Years
    Body Mass Index
    Beskrivning

    Collected in Exam 1

    Datatyp

    float

    Måttenheter
    • kg/m2
    Alias
    UMLS CUI [1,1]
    C1305855
    kg/m2
    Metabolic clearance rate of insulin
    Beskrivning

    Collected in Exam 1

    Datatyp

    float

    Alias
    UMLS CUI [1,1]
    C0025515
    UMLS CUI [1,2]
    C0021641
    M (insulin sensitivity) normalized by surface area/steady state plasma insulin
    Beskrivning

    Collected in Exam 1

    Datatyp

    float

    Alias
    UMLS CUI [1,1]
    C4049919
    UMLS CUI [1,2]
    C0456603
    UMLS CUI [1,3]
    C0005902
    UMLS CUI [1,4]
    C0678587
    UMLS CUI [1,5]
    C0032105
    UMLS CUI [1,6]
    C0021641
    Presence of Coronary artery disease
    Beskrivning

    Collected in Exam 1

    Datatyp

    text

    Alias
    UMLS CUI [1,1]
    C1956346
    UMLS CUI [1,2]
    C3854307
    Absence of Coronary artery disease
    Beskrivning

    Collected in Exam 1

    Datatyp

    text

    Alias
    UMLS CUI [1,1]
    C1956346
    UMLS CUI [1,2]
    C0332197
    Subject Ethnicity
    Beskrivning

    Collected in Exam 1

    Datatyp

    string

    Alias
    UMLS CUI [1,1]
    C0015031
    Gender of participant
    Beskrivning

    Collected in Exam 1

    Datatyp

    text

    Alias
    UMLS CUI [1,1]
    C0079399

    Similar models

    The dataset provides onformation of metabolic clearance rate of insulin, insulin sensitivity, BMI measurements, and presence/absence of coronary artery disease, in addition to basic socio-demographic information.

    Name
    Typ
    Description | Question | Decode (Coded Value)
    Datatyp
    Alias
    Item Group
    pht008418
    C3846158 (UMLS CUI [1,1])
    SUBJECT_ID
    Item
    De-identified Subject ID
    string
    C4684638 (UMLS CUI [1,1])
    C2348585 (UMLS CUI [1,2])
    AGE
    Item
    Subject age
    float
    C0001779 (UMLS CUI [1,1])
    BMI
    Item
    Body Mass Index
    float
    C1305855 (UMLS CUI [1,1])
    MCRI
    Item
    Metabolic clearance rate of insulin
    float
    C0025515 (UMLS CUI [1,1])
    C0021641 (UMLS CUI [1,2])
    SI
    Item
    M (insulin sensitivity) normalized by surface area/steady state plasma insulin
    float
    C4049919 (UMLS CUI [1,1])
    C0456603 (UMLS CUI [1,2])
    C0005902 (UMLS CUI [1,3])
    C0678587 (UMLS CUI [1,4])
    C0032105 (UMLS CUI [1,5])
    C0021641 (UMLS CUI [1,6])
    Item
    Presence of Coronary artery disease
    text
    C1956346 (UMLS CUI [1,1])
    C3854307 (UMLS CUI [1,2])
    Code List
    Presence of Coronary artery disease
    CL Item
    No (0)
    CL Item
    Yes (1)
    Item
    Absence of Coronary artery disease
    text
    C1956346 (UMLS CUI [1,1])
    C0332197 (UMLS CUI [1,2])
    Code List
    Absence of Coronary artery disease
    CL Item
    No (0)
    CL Item
    Yes (1)
    ETHNICITY
    Item
    Subject Ethnicity
    string
    C0015031 (UMLS CUI [1,1])
    Item
    Gender of participant
    text
    C0079399 (UMLS CUI [1,1])
    Code List
    Gender of participant
    CL Item
    Male (1)
    C0086582 (UMLS CUI [1,1])
    CL Item
    Female (2)
    C0086287 (UMLS CUI [1,1])

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