ID

45766

Beschreibung

Principal Investigator: Jerry L. Nadler, Eastern Virginia Medical School, Norfolk, VA, USA MeSH: Diabetes Mellitus, Type 2,Diabetes Complications https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs001130 The NIDDM-Atherosclerosis Study, funded by NHLBI, was designed as a family study to examine the genetic basis of subclinical atherosclerosis and diabetes in Hispanic families. Family members of probands with T2D were recruited in the Los Angeles area. The baseline examination of the cohort included the euglycemic hyperinsulinemic clamp test from which the two key phenotypes were obtained: insulin sensitivity (M) and metabolic clearance rate of insulin (MCRI). Genome-wide genotyping was obtained under separate funding by NIDDK as a part of the GUARDIAN (Genetics Underlying Diabetes in Hispanics) Consortium.

Link

dbGaP-study=phs001130

Stichworte

  1. 16.06.23 16.06.23 - Chiara Middel
Rechteinhaber

Jerry L. Nadler, Eastern Virginia Medical School, Norfolk, VA, USA

Hochgeladen am

16. Juni 2023

DOI

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Lizenz

Creative Commons BY 4.0

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dbGaP phs001130 NIDDM-Atherosclerosis Study (NIDDM-Athero)

The dataset provides onformation of metabolic clearance rate of insulin, insulin sensitivity, BMI measurements, and presence/absence of coronary artery disease, in addition to basic socio-demographic information.

pht008418
Beschreibung

pht008418

Alias
UMLS CUI [1,1]
C3846158
De-identified Subject ID
Beschreibung

Collected in Exam 1

Datentyp

string

Alias
UMLS CUI [1,1]
C4684638
UMLS CUI [1,2]
C2348585
Subject age
Beschreibung

Collected in Exam 1

Datentyp

float

Maßeinheiten
  • Years
Alias
UMLS CUI [1,1]
C0001779
Years
Body Mass Index
Beschreibung

Collected in Exam 1

Datentyp

float

Maßeinheiten
  • kg/m2
Alias
UMLS CUI [1,1]
C1305855
kg/m2
Metabolic clearance rate of insulin
Beschreibung

Collected in Exam 1

Datentyp

float

Alias
UMLS CUI [1,1]
C0025515
UMLS CUI [1,2]
C0021641
M (insulin sensitivity) normalized by surface area/steady state plasma insulin
Beschreibung

Collected in Exam 1

Datentyp

float

Alias
UMLS CUI [1,1]
C4049919
UMLS CUI [1,2]
C0456603
UMLS CUI [1,3]
C0005902
UMLS CUI [1,4]
C0678587
UMLS CUI [1,5]
C0032105
UMLS CUI [1,6]
C0021641
Presence of Coronary artery disease
Beschreibung

Collected in Exam 1

Datentyp

text

Alias
UMLS CUI [1,1]
C1956346
UMLS CUI [1,2]
C3854307
Absence of Coronary artery disease
Beschreibung

Collected in Exam 1

Datentyp

text

Alias
UMLS CUI [1,1]
C1956346
UMLS CUI [1,2]
C0332197
Subject Ethnicity
Beschreibung

Collected in Exam 1

Datentyp

string

Alias
UMLS CUI [1,1]
C0015031
Gender of participant
Beschreibung

Collected in Exam 1

Datentyp

text

Alias
UMLS CUI [1,1]
C0079399

Ähnliche Modelle

The dataset provides onformation of metabolic clearance rate of insulin, insulin sensitivity, BMI measurements, and presence/absence of coronary artery disease, in addition to basic socio-demographic information.

Name
Typ
Description | Question | Decode (Coded Value)
Datentyp
Alias
Item Group
pht008418
C3846158 (UMLS CUI [1,1])
SUBJECT_ID
Item
De-identified Subject ID
string
C4684638 (UMLS CUI [1,1])
C2348585 (UMLS CUI [1,2])
AGE
Item
Subject age
float
C0001779 (UMLS CUI [1,1])
BMI
Item
Body Mass Index
float
C1305855 (UMLS CUI [1,1])
MCRI
Item
Metabolic clearance rate of insulin
float
C0025515 (UMLS CUI [1,1])
C0021641 (UMLS CUI [1,2])
SI
Item
M (insulin sensitivity) normalized by surface area/steady state plasma insulin
float
C4049919 (UMLS CUI [1,1])
C0456603 (UMLS CUI [1,2])
C0005902 (UMLS CUI [1,3])
C0678587 (UMLS CUI [1,4])
C0032105 (UMLS CUI [1,5])
C0021641 (UMLS CUI [1,6])
Item
Presence of Coronary artery disease
text
C1956346 (UMLS CUI [1,1])
C3854307 (UMLS CUI [1,2])
Code List
Presence of Coronary artery disease
CL Item
No (0)
CL Item
Yes (1)
Item
Absence of Coronary artery disease
text
C1956346 (UMLS CUI [1,1])
C0332197 (UMLS CUI [1,2])
Code List
Absence of Coronary artery disease
CL Item
No (0)
CL Item
Yes (1)
ETHNICITY
Item
Subject Ethnicity
string
C0015031 (UMLS CUI [1,1])
Item
Gender of participant
text
C0079399 (UMLS CUI [1,1])
Code List
Gender of participant
CL Item
Male (1)
C0086582 (UMLS CUI [1,1])
CL Item
Female (2)
C0086287 (UMLS CUI [1,1])

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