ID
45710
Beschrijving
Principal Investigator: Michael P. Snyder, PhD, Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA MeSH: Esophageal Neoplasms https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs001214 Paired DNA and RNA profiling is increasingly employed in genomics research to uncover molecular mechanisms of disease and to explore personal genotype and phenotype correlations. We developed a novel simultaneous DNA and RNA sequencing approach (Simul-seq) that enables comprehensive genomic and transcriptomic profiles from small quantities of cells or tissues. In this study, Simul-seq was performed on patient-derived fibroblast cells as well as an esophageal adenocarcinoma tumor sample and compared with standard DNA and RNA-sequencing approaches.
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Trefwoorden
Versies (1)
- 17-05-23 17-05-23 - Chiara Middel
Houder van rechten
Michael P. Snyder, PhD, Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA
Geüploaded op
17 mei 2023
DOI
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Licentie
Creative Commons BY 4.0
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dbGaP phs001214 DNA and RNA Profiling Using Simultaneous Sequencing (Simul-seq)
The subject consent data table contains subject IDs, consent group information, subject source, and affection status for esophageal adenocarcinoma.
- StudyEvent: SEV1
- The subject consent data table contains subject IDs, consent group information, subject source, and affection status for esophageal adenocarcinoma.
- This subject sample mapping data table includes a mapping of study subject IDs to sample IDs. Samples are the final preps submitted for genotyping, sequencing, and/or expression data. For example, if one patient (subject ID) gave one sample, and that sample was processed differently to generate 2 sequencing runs, there would be two rows, both using the same subject ID, but having 2 unique sample IDs. The data table also includes sample source and sample use.
- This subject phenotype table includes gender and race of participant.
- This sample attributes table includes body site where sample was collected, analyte type, histological type, tumor status, metastasis status, tumor location, histologic and pathologic staging, tumor treatment, and sequencing center.
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The subject consent data table contains subject IDs, consent group information, subject source, and affection status for esophageal adenocarcinoma.
- StudyEvent: SEV1
- The subject consent data table contains subject IDs, consent group information, subject source, and affection status for esophageal adenocarcinoma.
- This subject sample mapping data table includes a mapping of study subject IDs to sample IDs. Samples are the final preps submitted for genotyping, sequencing, and/or expression data. For example, if one patient (subject ID) gave one sample, and that sample was processed differently to generate 2 sequencing runs, there would be two rows, both using the same subject ID, but having 2 unique sample IDs. The data table also includes sample source and sample use.
- This subject phenotype table includes gender and race of participant.
- This sample attributes table includes body site where sample was collected, analyte type, histological type, tumor status, metastasis status, tumor location, histologic and pathologic staging, tumor treatment, and sequencing center.
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