ID

45658

Description

Principal Investigator: Neil E Caporaso, MD, National Institutes of Health, Bethesda, MD, USA MeSH: Waldenstrom Macroglobulinemia,Lymphoplasmacytoid Lymphoma https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs001284 A discovery GWAS is performed, consisting of genotyping 221 Waldenstrom macroglobulinemia (WM) cases on the Illumina Omni Express 12v1.1 platform and analyzing the genotypes together with those of 3798 previously genotyped controls in a model taking into account gender, age, and principal components of ancestry (i.e., significant eigenvectors). Directly genotyped data are supplemented by imputation using the Haplotype Reference Consortium.

Lien

dbGaP study = phs001284

Mots-clés

  1. 23/03/2023 23/03/2023 - Simon Heim
Détendeur de droits

Neil E Caporaso, MD, National Institutes of Health, Bethesda, MD, USA

Téléchargé le

23 mars 2023

DOI

Pour une demande vous connecter.

Licence

Creative Commons BY 4.0

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dbGaP phs001284 NCI Waldenstrom Macroglobulinemia Genome-wide Association Study

Eligibility Criteria

Inclusion and exclusion criteria
Description

Inclusion and exclusion criteria

Alias
UMLS CUI [1,1]
C1512693
UMLS CUI [1,2]
C0680251
*Inclusion criteria, Cases:* Individuals with a confirmed diagnosis of Waldenstrom Macroglobulinemia or lymphoplasmacytic lymphoma who provide informed consent for DNA collection, genetic studies and data-sharing.
Description

*Inclusion criteria, Cases:* Individuals with a confirmed diagnosis of Waldenstrom Macroglobulinemia or lymphoplasmacytic lymphoma who provide informed consent for DNA collection, genetic studies and data-sharing.

Type de données

boolean

Alias
UMLS CUI [1,1]
C1512693
UMLS CUI [1,2]
C1706256
UMLS CUI [1,3]
C0011900
UMLS CUI [1,4]
C0750484
UMLS CUI [1,5]
C0024419
UMLS CUI [1,6]
C0334633
UMLS CUI [1,7]
C0021430
UMLS CUI [1,8]
C0012854
UMLS CUI [1,9]
C0200345
UMLS CUI [1,10]
C2827447
UMLS CUI [1,11]
C2713450
*Inclusion criteria, Controls:* Adults with no history of Waldenstrom macroglobulinemia, lymphoplasmacytic lymphoma, or other B-cell malignancy at enrollment who provide informed consent for DNA collection and genetic studies.
Description

*Inclusion criteria, Controls:* Adults with no history of Waldenstrom macroglobulinemia, lymphoplasmacytic lymphoma, or other B-cell malignancy at enrollment who provide informed consent for DNA collection and genetic studies.

Type de données

boolean

Alias
UMLS CUI [1,1]
C1512693
UMLS CUI [1,2]
C0009932
UMLS CUI [1,3]
C0001675
UMLS CUI [1,4]
C0332122
UMLS CUI [1,5]
C0024419
UMLS CUI [1,6]
C0334633
UMLS CUI [1,7]
C0079731
UMLS CUI [1,8]
C0021430
UMLS CUI [1,9]
C0012854
UMLS CUI [1,10]
C0200345
UMLS CUI [1,11]
C2827447
*Exclusion criteria:* 1) Diagnosis of monoclonal gammopathy of IgM type; 2) diagnosis of primary B-cell disorder other than Waldenstrom macroglobulinemia or lymphoplasmacytic lymphoma; 3) non-European ancestry
Description

*Exclusion criteria:* 1) Diagnosis of monoclonal gammopathy of IgM type; 2) diagnosis of primary B-cell disorder other than Waldenstrom macroglobulinemia or lymphoplasmacytic lymphoma; 3) non-European ancestry

Type de données

boolean

Alias
UMLS CUI [1,1]
C0680251
UMLS CUI [1,2]
C0011900
UMLS CUI [1,3]
C4288918
UMLS CUI [1,4]
C5555430
UMLS CUI [1,5]
C4723751
UMLS CUI [1,6]
C0024419
UMLS CUI [1,7]
C0334633
UMLS CUI [1,8]
C1518422
UMLS CUI [1,9]
C1257905

Similar models

Eligibility Criteria

Name
Type
Description | Question | Decode (Coded Value)
Type de données
Alias
Item Group
Inclusion and exclusion criteria
C1512693 (UMLS CUI [1,1])
C0680251 (UMLS CUI [1,2])
*Inclusion criteria, Cases:* Individuals with a confirmed diagnosis of Waldenstrom Macroglobulinemia or lymphoplasmacytic lymphoma who provide informed consent for DNA collection, genetic studies and data-sharing.
Item
*Inclusion criteria, Cases:* Individuals with a confirmed diagnosis of Waldenstrom Macroglobulinemia or lymphoplasmacytic lymphoma who provide informed consent for DNA collection, genetic studies and data-sharing.
boolean
C1512693 (UMLS CUI [1,1])
C1706256 (UMLS CUI [1,2])
C0011900 (UMLS CUI [1,3])
C0750484 (UMLS CUI [1,4])
C0024419 (UMLS CUI [1,5])
C0334633 (UMLS CUI [1,6])
C0021430 (UMLS CUI [1,7])
C0012854 (UMLS CUI [1,8])
C0200345 (UMLS CUI [1,9])
C2827447 (UMLS CUI [1,10])
C2713450 (UMLS CUI [1,11])
*Inclusion criteria, Controls:* Adults with no history of Waldenstrom macroglobulinemia, lymphoplasmacytic lymphoma, or other B-cell malignancy at enrollment who provide informed consent for DNA collection and genetic studies.
Item
*Inclusion criteria, Controls:* Adults with no history of Waldenstrom macroglobulinemia, lymphoplasmacytic lymphoma, or other B-cell malignancy at enrollment who provide informed consent for DNA collection and genetic studies.
boolean
C1512693 (UMLS CUI [1,1])
C0009932 (UMLS CUI [1,2])
C0001675 (UMLS CUI [1,3])
C0332122 (UMLS CUI [1,4])
C0024419 (UMLS CUI [1,5])
C0334633 (UMLS CUI [1,6])
C0079731 (UMLS CUI [1,7])
C0021430 (UMLS CUI [1,8])
C0012854 (UMLS CUI [1,9])
C0200345 (UMLS CUI [1,10])
C2827447 (UMLS CUI [1,11])
*Exclusion criteria:* 1) Diagnosis of monoclonal gammopathy of IgM type; 2) diagnosis of primary B-cell disorder other than Waldenstrom macroglobulinemia or lymphoplasmacytic lymphoma; 3) non-European ancestry
Item
*Exclusion criteria:* 1) Diagnosis of monoclonal gammopathy of IgM type; 2) diagnosis of primary B-cell disorder other than Waldenstrom macroglobulinemia or lymphoplasmacytic lymphoma; 3) non-European ancestry
boolean
C0680251 (UMLS CUI [1,1])
C0011900 (UMLS CUI [1,2])
C4288918 (UMLS CUI [1,3])
C5555430 (UMLS CUI [1,4])
C4723751 (UMLS CUI [1,5])
C0024419 (UMLS CUI [1,6])
C0334633 (UMLS CUI [1,7])
C1518422 (UMLS CUI [1,8])
C1257905 (UMLS CUI [1,9])

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