0 Evaluaciones

ID

45506

Descripción

Principal Investigator: Matthew Meyerson, MD, PhD, Broad Institute, Cambridge MA, Dana Farber Cancer Institute, Boston MA, USA MeSH: Carcinoma, Non-Small-Cell Lung https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs000488 Lung carcinoma is the leading cause of cancer death in the United States and world-wide; lung adenocarcinoma is the most common cause of lung cancer. Pilot studies of lung adenocarcinoma with hybrid-capture based whole exome sequencing will enable us to identify new targets for therapy and improve diagnosis. We will analyze a blend of whole exome and whole genome sequencing data as well as copy number and somatic mutation calls for 200 tumor and matched normal controls. When completed this study will represent the most comprehensive lung adenocarcinoma genome dataset to date.

Link

dbGap study = phs000488

Palabras clave

  1. 9/11/22 9/11/22 - Dr. med. Lucy Kessler
  2. 13/12/22 13/12/22 - Kristina Keller
Titular de derechos de autor

Matthew Meyerson, MD, PhD, Broad Institute, Cambridge MA, Dana Farber Cancer Institute, Boston MA, USA

Subido en

13 de diciembre de 2022

DOI

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Licencia

Creative Commons BY 4.0

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    dbGaP phs000488 Genomic Sequencing of Lung Adenocarcinoma

    Sample ID, subject ID, and sample use variables obtained from participants with lung adenocarcinoma and involved in the "Genomic Sequencing of Lung Adenocarcinoma" project.

    pht002910
    Descripción

    pht002910

    Alias
    UMLS CUI [1,1]
    C0370003 (Specimen)
    SNOMED
    123038009
    LOINC
    LP7593-9
    UMLS CUI [1,2]
    C0600091 (Identifier)
    SNOMED
    118522005
    LOINC
    LP31795-5
    UMLS CUI [2,1]
    C0200345 (Specimen Collection)
    SNOMED
    17636008
    UMLS CUI [2,2]
    C0457083 (Usage)
    SNOMED
    277889008
    Subject ID
    Descripción

    SUBJECT_ID

    Tipo de datos

    string

    Alias
    UMLS CUI [1,1]
    C2348584 (Subject Unique Identifier)
    Sample ID
    Descripción

    SAMPLE_ID

    Tipo de datos

    string

    Alias
    UMLS CUI [1,1]
    C1299222 (Sample identification number)
    SNOMED
    372274003
    Sample use. Array_SNP: SNP genotypes obtained using standard or custom microarrays; Seq_DNA_WholeExome: Whole exome sequencing; Seq_DNA_WholeGenome: Whole genome sequencing
    Descripción

    SAMPLE_USE

    Tipo de datos

    text

    Alias
    UMLS CUI [1,1]
    C0370003 (Specimen)
    SNOMED
    123038009
    LOINC
    LP7593-9
    UMLS CUI [1,2]
    C4027253 (collection and preparation of genetic sample material for laboratory analysis and report)
    UMLS CUI [1,3]
    C0022885 (Laboratory Procedures)
    SNOMED
    269814003

    Similar models

    Sample ID, subject ID, and sample use variables obtained from participants with lung adenocarcinoma and involved in the "Genomic Sequencing of Lung Adenocarcinoma" project.

    Name
    Tipo
    Description | Question | Decode (Coded Value)
    Tipo de datos
    Alias
    Item Group
    pht002910
    C0370003 (UMLS CUI [1,1])
    C0600091 (UMLS CUI [1,2])
    C0200345 (UMLS CUI [2,1])
    C0457083 (UMLS CUI [2,2])
    SUBJECT_ID
    Item
    Subject ID
    string
    C2348584 (UMLS CUI [1,1])
    SAMPLE_ID
    Item
    Sample ID
    string
    C1299222 (UMLS CUI [1,1])
    SAMPLE_USE
    Item
    Sample use. Array_SNP: SNP genotypes obtained using standard or custom microarrays; Seq_DNA_WholeExome: Whole exome sequencing; Seq_DNA_WholeGenome: Whole genome sequencing
    text
    C0370003 (UMLS CUI [1,1])
    C4027253 (UMLS CUI [1,2])
    C0022885 (UMLS CUI [1,3])

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