ID

45503

Descrizione

Principal Investigator: Geoffrey Ginsburg, MD, PhD, Institute for Genome Science and Policy, Duke University, Durham, NC, USA MeSH: Cardiovascular Diseases,Myocardial Infarction,Coronary Artery Disease https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs000551 Case control cohort: The details have been previously published: American Heart Journal. 2010;160:371-379 e372. Briefly, a nested case:control cohort of CATHGEN participants who had experienced death or MI (n = 250) after their index catheterization and age-, sex-, and race-matched controls (n = 250) who were free of death/MI 2 years after cardiac catheterization was identified as part of the MURDOCK Horizon 1 Cardiovascular Disease Study.21 Sufficient RNA for microarray analysis was available in 447 members of this cohort. Observational cohort: 224 sequential CATHGEN samples were selected for whole blood RNA analysis, of which, 191 had sufficient RNA for microarray analysis.

collegamento

dbGap study = phs000551

Keywords

  1. 03/11/22 03/11/22 - Simon Heim
  2. 13/12/22 13/12/22 - Kristina Keller
Titolare del copyright

Geoffrey Ginsburg, MD, PhD, Institute for Genome Science and Policy, Duke University, Durham, NC, USA

Caricato su

13 dicembre 2022

DOI

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Licenza

Creative Commons BY 4.0

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dbGaP phs000551 Gene expression in CAD

Subject ID, age, sex, race, history or transplantation, days from catheterization to death, death or myocardial infraction, coronary artery disease, hyperlipidemia, hypertension, smoking, and diabetes of participants with or without myocardial infraction or coronary artery disease and involved in the "Gene Expression Signatures in CATHGEN" project.

pht003063
Descrizione

pht003063

Unique Sample ID
Descrizione

subjid

Tipo di dati

text

Alias
UMLS CUI [1,1]
C1299222
Cohort
Descrizione

STUDY1

Tipo di dati

text

Alias
UMLS CUI [1,1]
C0599755
Diabetes
Descrizione

DIABETES

Tipo di dati

text

Alias
UMLS CUI [1,1]
C0011849
Race
Descrizione

RACE

Tipo di dati

text

Alias
UMLS CUI [1,1]
C0034510
Sex
Descrizione

SEX

Tipo di dati

text

Alias
UMLS CUI [1,1]
C0079399
Smoking
Descrizione

SMK_PRED

Tipo di dati

text

Alias
UMLS CUI [1,1]
C0543414
Hypertension
Descrizione

BPPRED

Tipo di dati

text

Alias
UMLS CUI [1,1]
C0020538
Hyperlipdemia
Descrizione

HYL_PRED

Tipo di dati

text

Alias
UMLS CUI [1,1]
C0020473
Coronary artery disease
Descrizione

cad

Tipo di dati

text

Alias
UMLS CUI [1,1]
C1956346
Days from catheterization to death, myocardial infarction, or last follow up
Descrizione

DeathOrMI_Time

Tipo di dati

text

Alias
UMLS CUI [1,1]
C0872291
UMLS CUI [1,2]
C0007430
UMLS CUI [1,3]
C1306577
UMLS CUI [1,4]
C0027051
UMLS CUI [1,5]
C5239465
Death or myocardial infarction in follow up
Descrizione

DeathOrMI_Event

Tipo di dati

text

Alias
UMLS CUI [1,1]
C0027051
UMLS CUI [1,2]
C1306577
UMLS CUI [1,3]
C4745109
Failed quality analysis
Descrizione

QC_POOR

Tipo di dati

text

Alias
UMLS CUI [1,1]
C0231175
UMLS CUI [1,2]
C0936012
UMLS CUI [1,3]
C0332306
History of cardiac transplantation
Descrizione

TRANSPLT

Tipo di dati

text

Alias
UMLS CUI [1,1]
C0262926
UMLS CUI [1,2]
C0018823
Subjects that were profiled in both OBS and CC studies
Descrizione

overlap

Tipo di dati

text

Alias
UMLS CUI [1,1]
C1706256
UMLS CUI [1,2]
C2003903
UMLS CUI [1,3]
C1706086
UMLS CUI [1,4]
C0947630

Similar models

Subject ID, age, sex, race, history or transplantation, days from catheterization to death, death or myocardial infraction, coronary artery disease, hyperlipidemia, hypertension, smoking, and diabetes of participants with or without myocardial infraction or coronary artery disease and involved in the "Gene Expression Signatures in CATHGEN" project.

Name
genere
Description | Question | Decode (Coded Value)
Tipo di dati
Alias
Item Group
pht003063
subjid
Item
Unique Sample ID
text
C1299222 (UMLS CUI [1,1])
Item
Cohort
text
C0599755 (UMLS CUI [1,1])
Code List
Cohort
CL Item
Case-control (CC)
CL Item
Observational (OBS)
Item
Diabetes
text
C0011849 (UMLS CUI [1,1])
Code List
Diabetes
CL Item
No (0)
CL Item
Yes (1)
Item
Race
text
C0034510 (UMLS CUI [1,1])
Code List
Race
CL Item
White (1)
CL Item
Black (2)
CL Item
Native American Indian (3)
CL Item
Other (4)
Item
Sex
text
C0079399 (UMLS CUI [1,1])
Code List
Sex
CL Item
Male (0)
CL Item
Female (1)
Item
Smoking
text
C0543414 (UMLS CUI [1,1])
Code List
Smoking
CL Item
No (0)
CL Item
Yes (1)
Item
Hypertension
text
C0020538 (UMLS CUI [1,1])
Code List
Hypertension
CL Item
No (0)
CL Item
Yes (1)
Item
Hyperlipdemia
text
C0020473 (UMLS CUI [1,1])
Code List
Hyperlipdemia
CL Item
No (0)
CL Item
Yes (1)
Item
Coronary artery disease
text
C1956346 (UMLS CUI [1,1])
Code List
Coronary artery disease
CL Item
No (0)
CL Item
Yes (1)
DeathOrMI_Time
Item
Days from catheterization to death, myocardial infarction, or last follow up
text
C0872291 (UMLS CUI [1,1])
C0007430 (UMLS CUI [1,2])
C1306577 (UMLS CUI [1,3])
C0027051 (UMLS CUI [1,4])
C5239465 (UMLS CUI [1,5])
Item
Death or myocardial infarction in follow up
text
C0027051 (UMLS CUI [1,1])
C1306577 (UMLS CUI [1,2])
C4745109 (UMLS CUI [1,3])
Code List
Death or myocardial infarction in follow up
CL Item
No (0)
CL Item
Yes (1)
Item
Failed quality analysis
text
C0231175 (UMLS CUI [1,1])
C0936012 (UMLS CUI [1,2])
C0332306 (UMLS CUI [1,3])
Code List
Failed quality analysis
CL Item
No (0)
CL Item
Yes (1)
Item
History of cardiac transplantation
text
C0262926 (UMLS CUI [1,1])
C0018823 (UMLS CUI [1,2])
Code List
History of cardiac transplantation
CL Item
No (0)
CL Item
Yes (1)
Item
Subjects that were profiled in both OBS and CC studies
text
C1706256 (UMLS CUI [1,1])
C2003903 (UMLS CUI [1,2])
C1706086 (UMLS CUI [1,3])
C0947630 (UMLS CUI [1,4])
Code List
Subjects that were profiled in both OBS and CC studies
CL Item
No (0)
CL Item
Yes (1)

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