ID

45503

Beschrijving

Principal Investigator: Geoffrey Ginsburg, MD, PhD, Institute for Genome Science and Policy, Duke University, Durham, NC, USA MeSH: Cardiovascular Diseases,Myocardial Infarction,Coronary Artery Disease https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs000551 Case control cohort: The details have been previously published: American Heart Journal. 2010;160:371-379 e372. Briefly, a nested case:control cohort of CATHGEN participants who had experienced death or MI (n = 250) after their index catheterization and age-, sex-, and race-matched controls (n = 250) who were free of death/MI 2 years after cardiac catheterization was identified as part of the MURDOCK Horizon 1 Cardiovascular Disease Study.21 Sufficient RNA for microarray analysis was available in 447 members of this cohort. Observational cohort: 224 sequential CATHGEN samples were selected for whole blood RNA analysis, of which, 191 had sufficient RNA for microarray analysis.

Link

dbGap study = phs000551

Trefwoorden

  1. 03-11-22 03-11-22 - Simon Heim
  2. 13-12-22 13-12-22 - Kristina Keller
Houder van rechten

Geoffrey Ginsburg, MD, PhD, Institute for Genome Science and Policy, Duke University, Durham, NC, USA

Geüploaded op

13 december 2022

DOI

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Licentie

Creative Commons BY 4.0

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dbGaP phs000551 Gene expression in CAD

Eligibility Criteria

Inclusion and exclusion criteria
Beschrijving

Inclusion and exclusion criteria

For both cohorts, subjects consented to participation in the Catheterization Genetics (CATHGEN) biorepository which has banked whole blood RNA in PAXgene® blood tubes from Duke University Medical Center patients at the time of cardiac catheterization.
Beschrijving

For both cohorts, subjects consented to participation in the Catheterization Genetics (CATHGEN) biorepository which has banked whole blood RNA in PAXgene® blood tubes from Duke University Medical Center patients at the time of cardiac catheterization.

Datatype

boolean

Alias
UMLS CUI [1,1]
C0021430
UMLS CUI [1,2]
C0679823
UMLS CUI [1,3]
C1711176
UMLS CUI [1,4]
C1608383
UMLS CUI [1,5]
C5420592
UMLS CUI [1,6]
C4288536
UMLS CUI [1,7]
C0000872
UMLS CUI [1,8]
C0030705
UMLS CUI [1,9]
C1442880
UMLS CUI [1,10]
C0018795

Similar models

Eligibility Criteria

Name
Type
Description | Question | Decode (Coded Value)
Datatype
Alias
Item Group
Inclusion and exclusion criteria
For both cohorts, subjects consented to participation in the Catheterization Genetics (CATHGEN) biorepository which has banked whole blood RNA in PAXgene® blood tubes from Duke University Medical Center patients at the time of cardiac catheterization.
Item
For both cohorts, subjects consented to participation in the Catheterization Genetics (CATHGEN) biorepository which has banked whole blood RNA in PAXgene® blood tubes from Duke University Medical Center patients at the time of cardiac catheterization.
boolean
C0021430 (UMLS CUI [1,1])
C0679823 (UMLS CUI [1,2])
C1711176 (UMLS CUI [1,3])
C1608383 (UMLS CUI [1,4])
C5420592 (UMLS CUI [1,5])
C4288536 (UMLS CUI [1,6])
C0000872 (UMLS CUI [1,7])
C0030705 (UMLS CUI [1,8])
C1442880 (UMLS CUI [1,9])
C0018795 (UMLS CUI [1,10])

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