ID
45480
Description
Principal Investigator: Markku Laakso, MD, PhD, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland MeSH: Metabolic Syndrome,Diabetes Mellitus, Type 2,Cardiovascular Diseases https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs000743 The METSIM Study includes 10,197 men, aged from 45 to 73 years, randomly selected from the population register of the town of Kuopio, Eastern Finland, and examined in 2005-2010. The aim of the study is to investigate genetic and non-genetic factors associated with the risk of type 2 diabetes (T2D), cardiovascular disease (CVD), and insulin resistance-related traits in a cross-sectional and longitudinal setting. Study protocol includes collection of data on CVD risk factors (smoking, exercise, diet, history of chronic diseases including coronary heart disease, stroke, cardiac failure, medication, history of diabetes or early onset coronary heart disease in the family), questionnaire on the FINDRISC Score, measurement of height, weight, waist, hip, blood pressure, and bioimpedance for the evaluation of fat percentage. July 2016 - This first study release includes phenotype and whole exome sequencing data of n=982 participants in substudy: Type 2 Diabetes Genetic Exploration by Next-Generation Sequencing in Multi-Ethnic Samples (T2D-GENES) Project 1: Metabolic Syndrome in Men Study (METSIM) - phs001100.v2.p1. The second release (v2) includes phenotype data for the entire METSIM cohort and makes two additional substudies available, phs000919.v1.p1 and phs000752.v1.p1. *The METSIM Study v2 is utilized in the following dbGaP sub-studies.* To view genotypes, other molecular data, and derived variables collected in these sub-studies, please click on the following sub-studies below or in the "Sub-studies" section of this top-level study page phs000743.v2.p1 METSIM Study v2. - phs000752 METSIM FinMetSeq Exome Sequencing - phs000919 METSIM GWAS and Exome Chip - phs001100 METSIM T2D-GENES Exome Sequencing
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- 12/13/22 12/13/22 - Chiara Middel
Copyright Holder
Markku Laakso, MD, PhD, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland
Uploaded on
December 13, 2022
DOI
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Creative Commons BY 4.0
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dbGaP phs000743 METSIM (METabolic Syndrome In Men) Study
Sample ID, analyte type, body site where sample was obtained, histological type of sample, and sequencing center of participants in the "Type 2 Diabetes Genetic Exploration by Next-Generation Sequencing in Multi-Ethnic Samples (T2D-GENES) Project 1: Metabolic Syndrome in Men Study (METSIM)" project.
- StudyEvent: SEV1
- Eligibility Criteria
- Subject ID and consent group of participants in the "METSIM (METabolic Syndrome In Men) Study" project.
- Subject ID, sample ID, sample use variable, and study of participants in the "METSIM (METabolic Syndrome In Men) Study" project.
- Sample ID, analyte type, and exome chip genotyping batch of participants in the "METSIM (METabolic Syndrome In Men) Study GWAS and Exome Chip" project.
- Sample ID, analyte type, and tissue type of sample obtained from participants in the "METSIM (METabolic Syndrome In Men) Study: FinMetSeq Exome Sequencing" project.
- Subject ID, age, plasma adiponectin, blood pressure, cholesterol, C-peptide, creatinine, diabetes, glucose, GHbA1C, GAD antibodies, insulin, triglycerides, weight, height, BMI, waist circumference and medications of participants in the "METSIM (METabolic Syndrome In Men) Study" project.
- Sample ID, analyte type, body site where sample was obtained, histological type of sample, and sequencing center of participants in the "Type 2 Diabetes Genetic Exploration by Next-Generation Sequencing in Multi-Ethnic Samples (T2D-GENES) Project 1: Metabolic Syndrome in Men Study (METSIM)" project.
- Subject ID, family ID, father, mother, sex, and ID of monozygotic twins of participants in the "METSIM (METabolic Syndrome In Men) Study" project.
Similar models
Sample ID, analyte type, body site where sample was obtained, histological type of sample, and sequencing center of participants in the "Type 2 Diabetes Genetic Exploration by Next-Generation Sequencing in Multi-Ethnic Samples (T2D-GENES) Project 1: Metabolic Syndrome in Men Study (METSIM)" project.
- StudyEvent: SEV1
- Eligibility Criteria
- Subject ID and consent group of participants in the "METSIM (METabolic Syndrome In Men) Study" project.
- Subject ID, sample ID, sample use variable, and study of participants in the "METSIM (METabolic Syndrome In Men) Study" project.
- Sample ID, analyte type, and exome chip genotyping batch of participants in the "METSIM (METabolic Syndrome In Men) Study GWAS and Exome Chip" project.
- Sample ID, analyte type, and tissue type of sample obtained from participants in the "METSIM (METabolic Syndrome In Men) Study: FinMetSeq Exome Sequencing" project.
- Subject ID, age, plasma adiponectin, blood pressure, cholesterol, C-peptide, creatinine, diabetes, glucose, GHbA1C, GAD antibodies, insulin, triglycerides, weight, height, BMI, waist circumference and medications of participants in the "METSIM (METabolic Syndrome In Men) Study" project.
- Sample ID, analyte type, body site where sample was obtained, histological type of sample, and sequencing center of participants in the "Type 2 Diabetes Genetic Exploration by Next-Generation Sequencing in Multi-Ethnic Samples (T2D-GENES) Project 1: Metabolic Syndrome in Men Study (METSIM)" project.
- Subject ID, family ID, father, mother, sex, and ID of monozygotic twins of participants in the "METSIM (METabolic Syndrome In Men) Study" project.
C1299222 (UMLS CUI [1,2])
C0565990 (UMLS CUI [1,2])
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