0 Ratings
ID

45480

Description

Principal Investigator: Markku Laakso, MD, PhD, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland MeSH: Metabolic Syndrome,Diabetes Mellitus, Type 2,Cardiovascular Diseases https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs000743 The METSIM Study includes 10,197 men, aged from 45 to 73 years, randomly selected from the population register of the town of Kuopio, Eastern Finland, and examined in 2005-2010. The aim of the study is to investigate genetic and non-genetic factors associated with the risk of type 2 diabetes (T2D), cardiovascular disease (CVD), and insulin resistance-related traits in a cross-sectional and longitudinal setting. Study protocol includes collection of data on CVD risk factors (smoking, exercise, diet, history of chronic diseases including coronary heart disease, stroke, cardiac failure, medication, history of diabetes or early onset coronary heart disease in the family), questionnaire on the FINDRISC Score, measurement of height, weight, waist, hip, blood pressure, and bioimpedance for the evaluation of fat percentage. July 2016 - This first study release includes phenotype and whole exome sequencing data of n=982 participants in substudy: Type 2 Diabetes Genetic Exploration by Next-Generation Sequencing in Multi-Ethnic Samples (T2D-GENES) Project 1: Metabolic Syndrome in Men Study (METSIM) - phs001100.v2.p1. The second release (v2) includes phenotype data for the entire METSIM cohort and makes two additional substudies available, phs000919.v1.p1 and phs000752.v1.p1. *The METSIM Study v2 is utilized in the following dbGaP sub-studies.* To view genotypes, other molecular data, and derived variables collected in these sub-studies, please click on the following sub-studies below or in the "Sub-studies" section of this top-level study page phs000743.v2.p1 METSIM Study v2. - phs000752 METSIM FinMetSeq Exome Sequencing - phs000919 METSIM GWAS and Exome Chip - phs001100 METSIM T2D-GENES Exome Sequencing

Link

dbGaP-study=phs000743

Keywords

Versions (1)
  1. 12/13/22 12/13/22 - Chiara Middel
Copyright Holder

Markku Laakso, MD, PhD, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland

Uploaded on

December 13, 2022

DOI

To request one please log in.

License

Creative Commons BY 4.0
Model comments :

You can comment on the data model here. Via the speech bubbles at the itemgroups and items you can add comments to those specificially.

Back to model comments
Itemgroup comments for :

Item comments for :

  • Newest
  • Oldest
  • Popular
  • Newest
    • Newest
    • Oldest
    • Popular

    No comments

    In order to download data models you must be logged in. Please log in or register for free.

    dbGaP phs000743 METSIM (METabolic Syndrome In Men) Study

    English

    Subject ID, age, plasma adiponectin, blood pressure, cholesterol, C-peptide, creatinine, diabetes, glucose, GHbA1C, GAD antibodies, insulin, triglycerides, weight, height, BMI, waist circumference and medications of participants in the "METSIM (METabolic Syndrome In Men) Study" project.

    8 forms  
    pht005603
    Description

    pht005603

    Alias
    UMLS CUI [1,1]
    C3846158
    Subject ID
    Description

    SUBJECT_ID

    Data type

    text

    Alias
    UMLS CUI [1,1]
    C2348585
    Sex
    Description

    sex

    Data type

    text

    Alias
    UMLS CUI [1,1]
    C0079399
    Age at METSIM baseline visit
    Description

    studyage

    Data type

    float

    Measurement units
    • years
    Alias
    UMLS CUI [1,1]
    C0001779
    UMLS CUI [1,2]
    C1442488
    UMLS CUI [1,3]
    C0545082
    years
    Type of diabetes
    Description

    dmtype

    Data type

    text

    Alias
    UMLS CUI [1,1]
    C0332307
    UMLS CUI [1,2]
    C0011849
    Glucose tolerance according to WHO 1997
    Description

    gltol6_1

    Data type

    text

    Alias
    UMLS CUI [1,1]
    C0178665
    Age of onset of diabetes
    Description

    aoo

    Data type

    text

    Measurement units
    • years
    Alias
    UMLS CUI [1,1]
    C0001779
    UMLS CUI [1,2]
    C0574845
    UMLS CUI [1,3]
    C0011849
    years
    OGTT fasting plasma glucose
    Description

    glu_fast

    Data type

    float

    Measurement units
    • mmol/l
    Alias
    UMLS CUI [1,1]
    C0029161
    UMLS CUI [1,2]
    C0583513
    mmol/l
    OGTT fasting plasma insulin
    Description

    ins_fast

    Data type

    float

    Measurement units
    • pmol/l
    Alias
    UMLS CUI [1,1]
    C0029161
    UMLS CUI [1,2]
    C0015663
    UMLS CUI [1,3]
    C0857690
    pmol/l
    Serum C-peptide
    Description

    cpep_fast

    Data type

    float

    Measurement units
    • nmol/l
    Alias
    UMLS CUI [1,1]
    C0006558
    UMLS CUI [1,2]
    C0229671
    nmol/l
    OGTT 120 min plasma glucose
    Description

    glu_2h

    Data type

    float

    Measurement units
    • mmol/l
    Alias
    UMLS CUI [1,1]
    C0202042
    UMLS CUI [1,2]
    C0029161
    UMLS CUI [1,3]
    C0429928
    UMLS CUI [1,4]
    C1292425
    mmol/l
    OGTT 120 min plasma insulin
    Description

    ins_2h

    Data type

    float

    Measurement units
    • pmol/l
    Alias
    UMLS CUI [1,1]
    C0029161
    UMLS CUI [1,2]
    C0429928
    UMLS CUI [1,3]
    C1292425
    UMLS CUI [1,4]
    C0032105
    UMLS CUI [1,5]
    C0021641
    pmol/l
    Blood GHbA1C
    Description

    hba1c

    Data type

    float

    Measurement units
    • %
    Alias
    UMLS CUI [1,1]
    C0019018
    %
    Plasma adiponectin
    Description

    p_adipon

    Data type

    float

    Measurement units
    • ug/ml
    Alias
    UMLS CUI [1,1]
    C0032105
    UMLS CUI [1,2]
    C2700366
    ug/ml
    Serum GAD antibodies
    Description

    s_gadab

    Data type

    float

    Measurement units
    • U/ml
    Alias
    UMLS CUI [1,1]
    C0229671
    UMLS CUI [1,2]
    C0443891
    U/ml
    Creatinine
    Description

    s_krea

    Data type

    text

    Measurement units
    • umol/l
    Alias
    UMLS CUI [1,1]
    C0201976
    umol/l
    Total cholesterol
    Description

    chol

    Data type

    float

    Measurement units
    • mmol/l
    Alias
    UMLS CUI [1,1]
    C0543421
    mmol/l
    LDL cholesterol
    Description

    ldl

    Data type

    float

    Measurement units
    • mmol/l
    Alias
    UMLS CUI [1,1]
    C0428474
    mmol/l
    HDL cholesterol
    Description

    hdl

    Data type

    float

    Measurement units
    • mmol/l
    Alias
    UMLS CUI [1,1]
    C0428472
    mmol/l
    Total triglycerides
    Description

    tg

    Data type

    float

    Measurement units
    • mmol/l
    Alias
    UMLS CUI [1,1]
    C0202236
    mmol/l
    Height
    Description

    height

    Data type

    float

    Measurement units
    • cm
    Alias
    UMLS CUI [1,1]
    C0005890
    cm
    Weight
    Description

    weight

    Data type

    float

    Measurement units
    • kg
    Alias
    UMLS CUI [1,1]
    C0005910
    kg
    Body mass index
    Description

    bmi

    Data type

    float

    Measurement units
    • kg/m^2
    Alias
    UMLS CUI [1,1]
    C1305855
    kg/m^2
    Hip circumference
    Description

    hip

    Data type

    float

    Measurement units
    • cm
    Alias
    UMLS CUI [1,1]
    C0562350
    cm
    Waist circumference
    Description

    waist

    Data type

    float

    Measurement units
    • cm
    Alias
    UMLS CUI [1,1]
    C0455829
    cm
    Systolic blood pressure
    Description

    sbp

    Data type

    float

    Measurement units
    • mmHg
    Alias
    UMLS CUI [1,1]
    C0871470
    mmHg
    Diastolic blood pressure
    Description

    dbp

    Data type

    float

    Measurement units
    • mmHg
    Alias
    UMLS CUI [1,1]
    C0428883
    mmHg
    Use of blood pressure medication
    Description

    bpmeds

    Data type

    text

    Alias
    UMLS CUI [1,1]
    C0005823
    UMLS CUI [1,2]
    C0013227
    Use of lipid medication
    Description

    lipidmeds

    Data type

    text

    Alias
    UMLS CUI [1,1]
    C0585943
    Use of diabetes medication
    Description

    diabmeds

    Data type

    text

    Alias
    UMLS CUI [1,1]
    C0935929
    Consortium name
    Description

    consortium

    Data type

    string

    Alias
    UMLS CUI [1,1]
    C1880171
    UMLS CUI [1,2]
    C0027365
    T2D-GENES cohort name
    Description

    cohort

    Data type

    string

    Alias
    UMLS CUI [1,1]
    C0599755
    UMLS CUI [1,2]
    C0027365
    Back to the top of the page

    Similar models

    Subject ID, age, plasma adiponectin, blood pressure, cholesterol, C-peptide, creatinine, diabetes, glucose, GHbA1C, GAD antibodies, insulin, triglycerides, weight, height, BMI, waist circumference and medications of participants in the "METSIM (METabolic Syndrome In Men) Study" project.

    8 forms
    Name
    Type
    Description | Question | Decode (Coded Value)
    Data type
    Alias
    Item Group
    pht005603
    C3846158 (UMLS CUI [1,1])
    SUBJECT_ID
    Item
    Subject ID
    text
    C2348585 (UMLS CUI [1,1])
    Item
    Sex
    text
    C0079399 (UMLS CUI [1,1])
    sex
    Code List
    Sex
    CL Item
    Female (F)
    C0086287 (UMLS CUI [1,1])
    CL Item
    Male (M)
    C0086582 (UMLS CUI [1,1])
    studyage
    Item
    Age at METSIM baseline visit
    float
    C0001779 (UMLS CUI [1,1])
    C1442488 (UMLS CUI [1,2])
    C0545082 (UMLS CUI [1,3])
    Item
    Type of diabetes
    text
    C0332307 (UMLS CUI [1,1])
    C0011849 (UMLS CUI [1,2])
    dmtype
    Code List
    Type of diabetes
    CL Item
    No DM (0)
    CL Item
    T1DM (1)
    CL Item
    T2DM (2)
    Item
    Glucose tolerance according to WHO 1997
    text
    C0178665 (UMLS CUI [1,1])
    gltol6_1
    Code List
    Glucose tolerance according to WHO 1997
    CL Item
    NGT (0)
    CL Item
    Isolated IFG (1)
    CL Item
    Isolated IGT (2)
    CL Item
    IFG & IGT (3)
    CL Item
    T1DM (4)
    CL Item
    New T2DM (5)
    CL Item
    Previous T2DM (6)
    aoo
    Item
    Age of onset of diabetes
    text
    C0001779 (UMLS CUI [1,1])
    C0574845 (UMLS CUI [1,2])
    C0011849 (UMLS CUI [1,3])
    glu_fast
    Item
    OGTT fasting plasma glucose
    float
    C0029161 (UMLS CUI [1,1])
    C0583513 (UMLS CUI [1,2])
    ins_fast
    Item
    OGTT fasting plasma insulin
    float
    C0029161 (UMLS CUI [1,1])
    C0015663 (UMLS CUI [1,2])
    C0857690 (UMLS CUI [1,3])
    cpep_fast
    Item
    Serum C-peptide
    float
    C0006558 (UMLS CUI [1,1])
    C0229671 (UMLS CUI [1,2])
    glu_2h
    Item
    OGTT 120 min plasma glucose
    float
    C0202042 (UMLS CUI [1,1])
    C0029161 (UMLS CUI [1,2])
    C0429928 (UMLS CUI [1,3])
    C1292425 (UMLS CUI [1,4])
    ins_2h
    Item
    OGTT 120 min plasma insulin
    float
    C0029161 (UMLS CUI [1,1])
    C0429928 (UMLS CUI [1,2])
    C1292425 (UMLS CUI [1,3])
    C0032105 (UMLS CUI [1,4])
    C0021641 (UMLS CUI [1,5])
    hba1c
    Item
    Blood GHbA1C
    float
    C0019018 (UMLS CUI [1,1])
    p_adipon
    Item
    Plasma adiponectin
    float
    C0032105 (UMLS CUI [1,1])
    C2700366 (UMLS CUI [1,2])
    s_gadab
    Item
    Serum GAD antibodies
    float
    C0229671 (UMLS CUI [1,1])
    C0443891 (UMLS CUI [1,2])
    s_krea
    Item
    Creatinine
    text
    C0201976 (UMLS CUI [1,1])
    chol
    Item
    Total cholesterol
    float
    C0543421 (UMLS CUI [1,1])
    ldl
    Item
    LDL cholesterol
    float
    C0428474 (UMLS CUI [1,1])
    hdl
    Item
    HDL cholesterol
    float
    C0428472 (UMLS CUI [1,1])
    tg
    Item
    Total triglycerides
    float
    C0202236 (UMLS CUI [1,1])
    height
    Item
    Height
    float
    C0005890 (UMLS CUI [1,1])
    weight
    Item
    Weight
    float
    C0005910 (UMLS CUI [1,1])
    bmi
    Item
    Body mass index
    float
    C1305855 (UMLS CUI [1,1])
    hip
    Item
    Hip circumference
    float
    C0562350 (UMLS CUI [1,1])
    waist
    Item
    Waist circumference
    float
    C0455829 (UMLS CUI [1,1])
    sbp
    Item
    Systolic blood pressure
    float
    C0871470 (UMLS CUI [1,1])
    dbp
    Item
    Diastolic blood pressure
    float
    C0428883 (UMLS CUI [1,1])
    Item
    Use of blood pressure medication
    text
    C0005823 (UMLS CUI [1,1])
    C0013227 (UMLS CUI [1,2])
    bpmeds
    Code List
    Use of blood pressure medication
    CL Item
    No use of blood pressure medication (0)
    CL Item
    Blood pressure medication used (1)
    Item
    Use of lipid medication
    text
    C0585943 (UMLS CUI [1,1])
    lipidmeds
    Code List
    Use of lipid medication
    CL Item
    No use of lipid medication (0)
    CL Item
    Lipid medication used (1)
    Item
    Use of diabetes medication
    text
    C0935929 (UMLS CUI [1,1])
    diabmeds
    Code List
    Use of diabetes medication
    CL Item
    No use of diabetes medication (0)
    CL Item
    Diabetes medication used (1)
    consortium
    Item
    Consortium name
    string
    C1880171 (UMLS CUI [1,1])
    C0027365 (UMLS CUI [1,2])
    cohort
    Item
    T2D-GENES cohort name
    string
    C0599755 (UMLS CUI [1,1])
    C0027365 (UMLS CUI [1,2])
    Back to the top of the page 

    Contact

    Please use this form for feedback, questions and suggestions for improvements.

    Fields marked with * are required.

    Help

    Do you need help on how to use the search function? Please watch the corresponding tutorial video for more details and learn how to use the search function most efficiently.

    Watch Tutorial