0 Evaluaciones

ID

45476

Descripción

Principal Investigator: Todd Lencz, PhD, Feinstein Institute for Medical Research, North Shore - LIJ Health System, Manhasset, NY, USA MeSH: Schizophrenia https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs000448 Schizophrenia is characterized by high heritability (~80%), yet the identification of susceptibility genes has proven extremely challenging. The Ashkenazi Jewish population, derived from a limited number of founders, may be enriched for a subset of susceptibility alleles, which may also have higher odds ratios than those detected by previous studies. GWAS was conducted in a large Ashkenazi case-control cohort, derived from the Hebrew University Genetic Resource, using the Illumina HumanOmni1-Quad BeadChip.

Link

dbGap study = phs000448

Palabras clave

  1. 26/10/22 26/10/22 - Simon Heim
  2. 13/12/22 13/12/22 - Kristina Keller
Titular de derechos de autor

Todd Lencz, PhD, Feinstein Institute for Medical Research, North Shore - LIJ Health System, Manhasset, NY, USA

Subido en

13 de diciembre de 2022

DOI

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Licencia

Creative Commons BY 4.0

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    dbGaP phs000448 Genetics of Schizophrenia in an Ashkenazi Jewish Case-Control Cohort

    Subject ID, age, place of subject birth, sex, race, diagnostic instrument, diagnosis, and age at diagnosis of participants with or without schizophrenia, obtained from the Ashkenazi Jewish population, and involved in the "Genetics of Schizophrenia in an Ashkenazi Jewish Case-Control Cohort" project.

    pht002510
    Descripción

    pht002510

    De-identified subject ID
    Descripción

    SUBJID

    Tipo de datos

    string

    Alias
    UMLS CUI [1,1]
    C4684638 (De-identified Information)
    UMLS CUI [1,2]
    C2348585 (Clinical Trial Subject Unique Identifier)
    Disease onset age
    Descripción

    Age

    Tipo de datos

    text

    Unidades de medida
    • years
    Alias
    UMLS CUI [1,1]
    C0206132 (Age of Onset)
    years
    Place of subject's birth
    Descripción

    Birthplace

    Tipo de datos

    string

    Alias
    UMLS CUI [1,1]
    C0032040 (Place of Birth)
    SNOMED
    169812000
    Gender of participant
    Descripción

    Sex

    Tipo de datos

    string

    Alias
    UMLS CUI [1,1]
    C0079399 (Gender)
    SNOMED
    263495000
    LOINC
    LP61312-2
    Race of participant
    Descripción

    RACE

    Tipo de datos

    string

    Alias
    UMLS CUI [1,1]
    C0034510 (Racial group)
    SNOMED
    415229000
    LOINC
    LP7528-5
    Diagnostic instrument [DSM-IV]
    Descripción

    Diagnostic_Instrument

    Tipo de datos

    text

    Alias
    UMLS CUI [1,1]
    C0587132 (Clinical diagnostic instrument)
    SNOMED
    309639004
    Diagnosis
    Descripción

    Diagnosis

    Tipo de datos

    text

    Alias
    UMLS CUI [1,1]
    C0011900 (Diagnosis)
    SNOMED
    439401001
    LOINC
    LP30831-9
    Age at diagnosis
    Descripción

    Age_at_Diagnosis

    Tipo de datos

    text

    Alias
    UMLS CUI [1,1]
    C1828181 (Age at diagnosis)
    SNOMED
    423493009
    LOINC
    LP114958-4

    Similar models

    Subject ID, age, place of subject birth, sex, race, diagnostic instrument, diagnosis, and age at diagnosis of participants with or without schizophrenia, obtained from the Ashkenazi Jewish population, and involved in the "Genetics of Schizophrenia in an Ashkenazi Jewish Case-Control Cohort" project.

    Name
    Tipo
    Description | Question | Decode (Coded Value)
    Tipo de datos
    Alias
    Item Group
    pht002510
    SUBJID
    Item
    De-identified subject ID
    string
    C4684638 (UMLS CUI [1,1])
    C2348585 (UMLS CUI [1,2])
    Age
    Item
    Disease onset age
    text
    C0206132 (UMLS CUI [1,1])
    Birthplace
    Item
    Place of subject's birth
    string
    C0032040 (UMLS CUI [1,1])
    Sex
    Item
    Gender of participant
    string
    C0079399 (UMLS CUI [1,1])
    RACE
    Item
    Race of participant
    string
    C0034510 (UMLS CUI [1,1])
    Diagnostic_Instrument
    Item
    Diagnostic instrument [DSM-IV]
    text
    C0587132 (UMLS CUI [1,1])
    Diagnosis
    Item
    Diagnosis
    text
    C0011900 (UMLS CUI [1,1])
    Age_at_Diagnosis
    Item
    Age at diagnosis
    text
    C1828181 (UMLS CUI [1,1])

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