Information:
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ID
45453
Description
Principal Investigator: Winnie Liang, PhD, Translational Genomics Research Institute, Phoenix, AZ, USA MeSH: https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs000745 In this study, RNA sequencing was performed on astrocytes microdissected from the posterior cingulate cortex of Alzheimer's disease subjects and healthy elderly controls.
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Keywords
Versions (1)
- 12/11/22 12/11/22 - Chiara Middel
Copyright Holder
Winnie Liang, PhD, Translational Genomics Research Institute, Phoenix, AZ, USA
Uploaded on
December 11, 2022
DOI
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License
Creative Commons BY 4.0
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dbGaP phs000745 RNAseq analysis of posterior cingulate astrocytes in Alzheimer's disease
Eligibility Criteria
- StudyEvent: SEV1
- Eligibility Criteria
- Subject - Consent - Affection Status Information
- Subject - Sample Mapping
- The dataset contains data about the APOE genotype, Braak-, NIA-R scores, density of plaques observed, age at time of death and time elapsed between death and tissue preparation, in addition to race and age of subjects.
- Sample - Attribute Information
Similar models
Eligibility Criteria
- StudyEvent: SEV1
- Eligibility Criteria
- Subject - Consent - Affection Status Information
- Subject - Sample Mapping
- The dataset contains data about the APOE genotype, Braak-, NIA-R scores, density of plaques observed, age at time of death and time elapsed between death and tissue preparation, in addition to race and age of subjects.
- Sample - Attribute Information
Name
Type
Description | Question | Decode (Coded Value)
Data type
Alias
Item Group
Inclusion and exclusion criteria
C1512693 (UMLS CUI [1,1])
C0680251 (UMLS CUI [1,2])
C0680251 (UMLS CUI [1,2])
Elig.phs000745.v1.p1.1
Item
Alzheimer's subjects had expired ages > 65, frequent plaque densities, Braak scores of at least IV, and intermediate to high criteria met for NIA-R.
boolean
C1698493 (UMLS CUI [1,1])
C0002395 (UMLS CUI [1,2])
C0001779 (UMLS CUI [1,3])
C0332461 (UMLS CUI [1,4])
C0178587 (UMLS CUI [1,5])
C0449394 (UMLS CUI [1,6])
C0205250 (UMLS CUI [1,7])
C0449820 (UMLS CUI [1,8])
C0679228 (UMLS CUI [1,9])
C0205250 (UMLS CUI [1,10])
C0205103 (UMLS CUI [1,11])
C0002395 (UMLS CUI [1,2])
C0001779 (UMLS CUI [1,3])
C0332461 (UMLS CUI [1,4])
C0178587 (UMLS CUI [1,5])
C0449394 (UMLS CUI [1,6])
C0205250 (UMLS CUI [1,7])
C0449820 (UMLS CUI [1,8])
C0679228 (UMLS CUI [1,9])
C0205250 (UMLS CUI [1,10])
C0205103 (UMLS CUI [1,11])
Elig.phs000745.v1.p1.2
Item
Healthy elderly controls had expired ages of > 65, zero to moderate plaque densities, Braak scores less than or equal to IV, and no criteria met for NIA-R.
boolean
C2986479 (UMLS CUI [1,1])
C0001779 (UMLS CUI [1,2])
C0332461 (UMLS CUI [1,3])
C0178587 (UMLS CUI [1,4])
C0449394 (UMLS CUI [1,5])
C0449820 (UMLS CUI [1,6])
C0679228 (UMLS CUI [1,7])
C0001779 (UMLS CUI [1,2])
C0332461 (UMLS CUI [1,3])
C0178587 (UMLS CUI [1,4])
C0449394 (UMLS CUI [1,5])
C0449820 (UMLS CUI [1,6])
C0679228 (UMLS CUI [1,7])