ID

45453

Description

Principal Investigator: Winnie Liang, PhD, Translational Genomics Research Institute, Phoenix, AZ, USA MeSH: https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs000745 In this study, RNA sequencing was performed on astrocytes microdissected from the posterior cingulate cortex of Alzheimer's disease subjects and healthy elderly controls.

Lien

dbGaP-study=phs000745

Mots-clés

  1. 11/12/2022 11/12/2022 - Chiara Middel
Détendeur de droits

Winnie Liang, PhD, Translational Genomics Research Institute, Phoenix, AZ, USA

Téléchargé le

11 décembre 2022

DOI

Pour une demande vous connecter.

Licence

Creative Commons BY 4.0

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dbGaP phs000745 RNAseq analysis of posterior cingulate astrocytes in Alzheimer's disease

Eligibility Criteria

Inclusion and exclusion criteria
Description

Inclusion and exclusion criteria

Alias
UMLS CUI [1,1]
C1512693
UMLS CUI [1,2]
C0680251
Alzheimer's subjects had expired ages > 65, frequent plaque densities, Braak scores of at least IV, and intermediate to high criteria met for NIA-R.
Description

Elig.phs000745.v1.p1.1

Type de données

boolean

Alias
UMLS CUI [1,1]
C1698493
UMLS CUI [1,2]
C0002395
UMLS CUI [1,3]
C0001779
UMLS CUI [1,4]
C0332461
UMLS CUI [1,5]
C0178587
UMLS CUI [1,6]
C0449394
UMLS CUI [1,7]
C0205250
UMLS CUI [1,8]
C0449820
UMLS CUI [1,9]
C0679228
UMLS CUI [1,10]
C0205250
UMLS CUI [1,11]
C0205103
Healthy elderly controls had expired ages of > 65, zero to moderate plaque densities, Braak scores less than or equal to IV, and no criteria met for NIA-R.
Description

Elig.phs000745.v1.p1.2

Type de données

boolean

Alias
UMLS CUI [1,1]
C2986479
UMLS CUI [1,2]
C0001779
UMLS CUI [1,3]
C0332461
UMLS CUI [1,4]
C0178587
UMLS CUI [1,5]
C0449394
UMLS CUI [1,6]
C0449820
UMLS CUI [1,7]
C0679228

Similar models

Eligibility Criteria

Name
Type
Description | Question | Decode (Coded Value)
Type de données
Alias
Item Group
Inclusion and exclusion criteria
C1512693 (UMLS CUI [1,1])
C0680251 (UMLS CUI [1,2])
Elig.phs000745.v1.p1.1
Item
Alzheimer's subjects had expired ages > 65, frequent plaque densities, Braak scores of at least IV, and intermediate to high criteria met for NIA-R.
boolean
C1698493 (UMLS CUI [1,1])
C0002395 (UMLS CUI [1,2])
C0001779 (UMLS CUI [1,3])
C0332461 (UMLS CUI [1,4])
C0178587 (UMLS CUI [1,5])
C0449394 (UMLS CUI [1,6])
C0205250 (UMLS CUI [1,7])
C0449820 (UMLS CUI [1,8])
C0679228 (UMLS CUI [1,9])
C0205250 (UMLS CUI [1,10])
C0205103 (UMLS CUI [1,11])
Elig.phs000745.v1.p1.2
Item
Healthy elderly controls had expired ages of > 65, zero to moderate plaque densities, Braak scores less than or equal to IV, and no criteria met for NIA-R.
boolean
C2986479 (UMLS CUI [1,1])
C0001779 (UMLS CUI [1,2])
C0332461 (UMLS CUI [1,3])
C0178587 (UMLS CUI [1,4])
C0449394 (UMLS CUI [1,5])
C0449820 (UMLS CUI [1,6])
C0679228 (UMLS CUI [1,7])

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