ID

45114

Descripción

Principal Investigator: Stephen V. Faraone, PhD, Departments of Psychiatry and Neuroscience and Physiology, SUNY Upstate Medical University, Syracuse, NY, USA MeSH: Attention Deficit Hyperactivity Disorder https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs000358 The PUWMa GWAS of ADHD is a multi-site collaboration initiated to conduct a family-based association study from existing research samples. The source sample of ADHD families was ascertained at Massachusetts General Hospital (MGH, N=309 trios), Washington University at St. Louis (WASH-U, N=272 trios), and University of California at Los Angeles (UCLA, N=156 trios). All offspring met criteria for DSM-IV-TR attention-deficit hyperactivity disorder with childhood onset.

Link

https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs000358

Palabras clave

Versiones (2)
  1. 30/08/2022 30/08/2022 - Simon Heim
  2. 12/10/2022 12/10/2022 - Adrian Schulz
Titular de derechos de autor

Stephen V. Faraone, PhD, Departments of Psychiatry and Neuroscience and Physiology, SUNY Upstate Medical University, Syracuse, NY, USA

Subido en

30 août 2022

DOI

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Licencia

Creative Commons BY 4.0
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dbGaP phs000358 PGC: the PUWMa GWAS of ADHD

Inglés

Eligibility Criteria

5 formularios  
Inclusion and exclusion criteria
Descripción

Inclusion and exclusion criteria

At MGH, initial affection status was based on DSM-IIIR criteria but lifetime DSM-IV-TR criteria was confirmed with Schedule for Affective Disorders and Schizophrenia for School-Age Children Epidemiologic Version (K-SADSE) at follow-up assessments. At UCLA, children and adolescents were assessed using the Schedule for Affective Disorders and Schizophrenia for School-Age Children-Present and Lifetime version (K-SADS-PL). At WASH-U subjects were assessed with the Missouri Assessment of Genetics Interview for Children (MAGIC), a semi-structured psychiatric interview allowing DSM-III, DSM-IV, and ICD-10 diagnoses. Cases were excluded if they were positive for any of the following: neurological disorder, head injury resulting in concussion, lifetime diagnoses of schizophrenia or autism. With regard to cognitive ability, MGH and UCLA subjects with estimated Full Scale IQ was <80 or <70, respectively were excluded while subjects at WASH-U were excluded if parents reported mental retardation.
Descripción

At MGH, initial affection status was based on DSM-IIIR criteria but lifetime DSM-IV-TR criteria was confirmed with Schedule for Affective Disorders and Schizophrenia for School-Age Children Epidemiologic Version (K-SADSE) at follow-up assessments. At UCLA, children and adolescents were assessed using the Schedule for Affective Disorders and Schizophrenia for School-Age Children-Present and Lifetime version (K-SADS-PL). At WASH-U subjects were assessed with the Missouri Assessment of Genetics Interview for Children (MAGIC), a semi-structured psychiatric interview allowing DSM-III, DSM-IV, and ICD-10 diagnoses. Cases were excluded if they were positive for any of the following: neurological disorder, head injury resulting in concussion, lifetime diagnoses of schizophrenia or autism. With regard to cognitive ability, MGH and UCLA subjects with estimated Full Scale IQ was <80 or <70, respectively were excluded while subjects at WASH-U were excluded if parents reported mental retardation.

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C1512693
UMLS CUI [1,2]
C0522476
UMLS CUI [1,3]
C1263846
UMLS CUI [2,1]
C0680251
UMLS CUI [2,2]
C0027765
UMLS CUI [2,3]
C0006107
UMLS CUI [2,4]
C0011900
UMLS CUI [2,5]
C0036341
UMLS CUI [2,6]
C0004352
UMLS CUI [2,7]
C0848034
UMLS CUI [2,8]
C0025362
Volver a la parte superior de la página

Similar models

Eligibility Criteria

5 formularios
Name
Tipo
Description | Question | Decode (Coded Value)
Tipo de datos
Alias
Item Group
Inclusion and exclusion criteria
At MGH, initial affection status was based on DSM-IIIR criteria but lifetime DSM-IV-TR criteria was confirmed with Schedule for Affective Disorders and Schizophrenia for School-Age Children Epidemiologic Version (K-SADSE) at follow-up assessments. At UCLA, children and adolescents were assessed using the Schedule for Affective Disorders and Schizophrenia for School-Age Children-Present and Lifetime version (K-SADS-PL). At WASH-U subjects were assessed with the Missouri Assessment of Genetics Interview for Children (MAGIC), a semi-structured psychiatric interview allowing DSM-III, DSM-IV, and ICD-10 diagnoses. Cases were excluded if they were positive for any of the following: neurological disorder, head injury resulting in concussion, lifetime diagnoses of schizophrenia or autism. With regard to cognitive ability, MGH and UCLA subjects with estimated Full Scale IQ was <80 or <70, respectively were excluded while subjects at WASH-U were excluded if parents reported mental retardation.
Item
At MGH, initial affection status was based on DSM-IIIR criteria but lifetime DSM-IV-TR criteria was confirmed with Schedule for Affective Disorders and Schizophrenia for School-Age Children Epidemiologic Version (K-SADSE) at follow-up assessments. At UCLA, children and adolescents were assessed using the Schedule for Affective Disorders and Schizophrenia for School-Age Children-Present and Lifetime version (K-SADS-PL). At WASH-U subjects were assessed with the Missouri Assessment of Genetics Interview for Children (MAGIC), a semi-structured psychiatric interview allowing DSM-III, DSM-IV, and ICD-10 diagnoses. Cases were excluded if they were positive for any of the following: neurological disorder, head injury resulting in concussion, lifetime diagnoses of schizophrenia or autism. With regard to cognitive ability, MGH and UCLA subjects with estimated Full Scale IQ was <80 or <70, respectively were excluded while subjects at WASH-U were excluded if parents reported mental retardation.
boolean
C1512693 (UMLS CUI [1,1])
C0522476 (UMLS CUI [1,2])
C1263846 (UMLS CUI [1,3])
C0680251 (UMLS CUI [2,1])
C0027765 (UMLS CUI [2,2])
C0006107 (UMLS CUI [2,3])
C0011900 (UMLS CUI [2,4])
C0036341 (UMLS CUI [2,5])
C0004352 (UMLS CUI [2,6])
C0848034 (UMLS CUI [2,7])
C0025362 (UMLS CUI [2,8])
Volver a la parte superior de la página 

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