ID

45114

Beschreibung

Principal Investigator: Stephen V. Faraone, PhD, Departments of Psychiatry and Neuroscience and Physiology, SUNY Upstate Medical University, Syracuse, NY, USA MeSH: Attention Deficit Hyperactivity Disorder https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs000358 The PUWMa GWAS of ADHD is a multi-site collaboration initiated to conduct a family-based association study from existing research samples. The source sample of ADHD families was ascertained at Massachusetts General Hospital (MGH, N=309 trios), Washington University at St. Louis (WASH-U, N=272 trios), and University of California at Los Angeles (UCLA, N=156 trios). All offspring met criteria for DSM-IV-TR attention-deficit hyperactivity disorder with childhood onset.

Link

https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs000358

Stichworte

Versionen (2)
  1. 30.08.22 30.08.22 - Simon Heim
  2. 12.10.22 12.10.22 - Adrian Schulz
Rechteinhaber

Stephen V. Faraone, PhD, Departments of Psychiatry and Neuroscience and Physiology, SUNY Upstate Medical University, Syracuse, NY, USA

Hochgeladen am

30. August 2022

DOI

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Lizenz

Creative Commons BY 4.0
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dbGaP phs000358 PGC: the PUWMa GWAS of ADHD

Englisch

Eligibility Criteria

5 Formulare  
Inclusion and exclusion criteria
Beschreibung

Inclusion and exclusion criteria

At MGH, initial affection status was based on DSM-IIIR criteria but lifetime DSM-IV-TR criteria was confirmed with Schedule for Affective Disorders and Schizophrenia for School-Age Children Epidemiologic Version (K-SADSE) at follow-up assessments. At UCLA, children and adolescents were assessed using the Schedule for Affective Disorders and Schizophrenia for School-Age Children-Present and Lifetime version (K-SADS-PL). At WASH-U subjects were assessed with the Missouri Assessment of Genetics Interview for Children (MAGIC), a semi-structured psychiatric interview allowing DSM-III, DSM-IV, and ICD-10 diagnoses. Cases were excluded if they were positive for any of the following: neurological disorder, head injury resulting in concussion, lifetime diagnoses of schizophrenia or autism. With regard to cognitive ability, MGH and UCLA subjects with estimated Full Scale IQ was <80 or <70, respectively were excluded while subjects at WASH-U were excluded if parents reported mental retardation.
Beschreibung

At MGH, initial affection status was based on DSM-IIIR criteria but lifetime DSM-IV-TR criteria was confirmed with Schedule for Affective Disorders and Schizophrenia for School-Age Children Epidemiologic Version (K-SADSE) at follow-up assessments. At UCLA, children and adolescents were assessed using the Schedule for Affective Disorders and Schizophrenia for School-Age Children-Present and Lifetime version (K-SADS-PL). At WASH-U subjects were assessed with the Missouri Assessment of Genetics Interview for Children (MAGIC), a semi-structured psychiatric interview allowing DSM-III, DSM-IV, and ICD-10 diagnoses. Cases were excluded if they were positive for any of the following: neurological disorder, head injury resulting in concussion, lifetime diagnoses of schizophrenia or autism. With regard to cognitive ability, MGH and UCLA subjects with estimated Full Scale IQ was <80 or <70, respectively were excluded while subjects at WASH-U were excluded if parents reported mental retardation.

Datentyp

boolean

Alias
UMLS CUI [1,1]
C1512693
UMLS CUI [1,2]
C0522476
UMLS CUI [1,3]
C1263846
UMLS CUI [2,1]
C0680251
UMLS CUI [2,2]
C0027765
UMLS CUI [2,3]
C0006107
UMLS CUI [2,4]
C0011900
UMLS CUI [2,5]
C0036341
UMLS CUI [2,6]
C0004352
UMLS CUI [2,7]
C0848034
UMLS CUI [2,8]
C0025362
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Ähnliche Modelle

Eligibility Criteria

5 Formulare
Name
Typ
Description | Question | Decode (Coded Value)
Datentyp
Alias
Item Group
Inclusion and exclusion criteria
At MGH, initial affection status was based on DSM-IIIR criteria but lifetime DSM-IV-TR criteria was confirmed with Schedule for Affective Disorders and Schizophrenia for School-Age Children Epidemiologic Version (K-SADSE) at follow-up assessments. At UCLA, children and adolescents were assessed using the Schedule for Affective Disorders and Schizophrenia for School-Age Children-Present and Lifetime version (K-SADS-PL). At WASH-U subjects were assessed with the Missouri Assessment of Genetics Interview for Children (MAGIC), a semi-structured psychiatric interview allowing DSM-III, DSM-IV, and ICD-10 diagnoses. Cases were excluded if they were positive for any of the following: neurological disorder, head injury resulting in concussion, lifetime diagnoses of schizophrenia or autism. With regard to cognitive ability, MGH and UCLA subjects with estimated Full Scale IQ was <80 or <70, respectively were excluded while subjects at WASH-U were excluded if parents reported mental retardation.
Item
At MGH, initial affection status was based on DSM-IIIR criteria but lifetime DSM-IV-TR criteria was confirmed with Schedule for Affective Disorders and Schizophrenia for School-Age Children Epidemiologic Version (K-SADSE) at follow-up assessments. At UCLA, children and adolescents were assessed using the Schedule for Affective Disorders and Schizophrenia for School-Age Children-Present and Lifetime version (K-SADS-PL). At WASH-U subjects were assessed with the Missouri Assessment of Genetics Interview for Children (MAGIC), a semi-structured psychiatric interview allowing DSM-III, DSM-IV, and ICD-10 diagnoses. Cases were excluded if they were positive for any of the following: neurological disorder, head injury resulting in concussion, lifetime diagnoses of schizophrenia or autism. With regard to cognitive ability, MGH and UCLA subjects with estimated Full Scale IQ was <80 or <70, respectively were excluded while subjects at WASH-U were excluded if parents reported mental retardation.
boolean
C1512693 (UMLS CUI [1,1])
C0522476 (UMLS CUI [1,2])
C1263846 (UMLS CUI [1,3])
C0680251 (UMLS CUI [2,1])
C0027765 (UMLS CUI [2,2])
C0006107 (UMLS CUI [2,3])
C0011900 (UMLS CUI [2,4])
C0036341 (UMLS CUI [2,5])
C0004352 (UMLS CUI [2,6])
C0848034 (UMLS CUI [2,7])
C0025362 (UMLS CUI [2,8])
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