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ID

45111

Description

Principal Investigator: Mark A. Rubin, MD, Weill Cornell Medical College, New York, NY, USA MeSH: Prostatic Neoplasms https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs000311 We have developed FusionSeq to identify fusion transcripts from paired-end RNA-sequencing. FusionSeq includes filters to remove spurious candidate fusions with artifacts such as misalignments or random pairing of transcript fragments and it ranks candidates according to several statistics. It also has a module to identify exact sequences at breakpoint junctions. FusionSeq detected known and novel fusions in a specially sequenced calibration data set, including 8 cancers with and without known rearrangements.

Link

https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs000311

Keywords

Versions (2)
  1. 8/28/22 8/28/22 - Simon Heim
  2. 10/12/22 10/12/22 - Adrian Schulz
Copyright Holder

Mark A. Rubin, MD, Weill Cornell Medical College, New York, NY, USA

Uploaded on

August 28, 2022

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Creative Commons BY 4.0
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    dbGaP phs000311 FusionSeq: Finding Fusions with Paired-End RNA-Seq

    English

    Eligibility Criteria

    5 forms  
    Inclusion and exclusion criteria
    Description

    Inclusion and exclusion criteria

    Prostate tissues collected post-robotic prostatectomy surgery and containing high-density tumor areas were used for this study. DNA samples in the study were extracted from tissue and blood, which were collected prior to the prostatectomy surgery.
    Description

    Prostate tissues collected post-robotic prostatectomy surgery and containing high-density tumor areas were used for this study. DNA samples in the study were extracted from tissue and blood, which were collected prior to the prostatectomy surgery.

    Data type

    boolean

    Alias
    UMLS CUI [1,1]
    C1512693
    UMLS CUI [1,2]
    C0586597
    UMLS CUI [1,3]
    C2922133
    UMLS CUI [1,4]
    C0027651
    UMLS CUI [1,5]
    C1268672
    UMLS CUI [2,1]
    C1512693
    UMLS CUI [2,2]
    C0012854
    UMLS CUI [2,3]
    C0370003
    UMLS CUI [2,4]
    C0586597
    UMLS CUI [2,5]
    C0178913
    UMLS CUI [2,6]
    C0332152
    UMLS CUI [2,7]
    C0033573
    Back to the top of the page

    Similar models

    Eligibility Criteria

    5 forms
    Name
    Type
    Description | Question | Decode (Coded Value)
    Data type
    Alias
    Item Group
    Inclusion and exclusion criteria
    Prostate tissues collected post-robotic prostatectomy surgery and containing high-density tumor areas were used for this study. DNA samples in the study were extracted from tissue and blood, which were collected prior to the prostatectomy surgery.
    Item
    Prostate tissues collected post-robotic prostatectomy surgery and containing high-density tumor areas were used for this study. DNA samples in the study were extracted from tissue and blood, which were collected prior to the prostatectomy surgery.
    boolean
    C1512693 (UMLS CUI [1,1])
    C0586597 (UMLS CUI [1,2])
    C2922133 (UMLS CUI [1,3])
    C0027651 (UMLS CUI [1,4])
    C1268672 (UMLS CUI [1,5])
    C1512693 (UMLS CUI [2,1])
    C0012854 (UMLS CUI [2,2])
    C0370003 (UMLS CUI [2,3])
    C0586597 (UMLS CUI [2,4])
    C0178913 (UMLS CUI [2,5])
    C0332152 (UMLS CUI [2,6])
    C0033573 (UMLS CUI [2,7])
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