ID
42476
Beschrijving
Study Title: LEOSS: Lean European Open Survey on SARS-CoV-2 Infected Patients https://leoss.net Study Indication: COVID-19 Date: 19.03.2021 Published with permission by Prof. Dr. med. J.-J. Vehreschild. LEOSS, a multi-center cohort study, has been created to get more in-depth knowledge about the epidemiology and clinical course of patients infected with SARS-CoV-2. Initiated by the ESCMID Emerging Infections Task Force (EITaF) and the German Infectious Disease Society, and supported by all German Centers for Health Research (DZG), LEOSS has developed into an international network of contributors. Via an integrative research approach with anonymous recruitment and collection of routine data in an open science context, LEOSS is building a uniform clinical dataset and providing real-time analyses. For more information feel free to explore https://leoss.net/. Please note that only cases with known outcome are collected! Baseline / diagnosis is defined as the day the sample of the first positive SARS-CoV-2 result was taken. Criteria of the Uncomplicated Phase: Asymptomatic OR Symptoms of upper respiratory tract infection and/or Nausea, emesis, diarrhea and/or Fever Remember: The Uncomplicated Phase ends, if a previously febrile patient has no fever anymore and has completed 14 days of follow-up without entering Complicated or Critical Phase; then move to Recovery Phase. Also, as soon as one of the criteria of the Complicated or Critical Phase are fulfilled, Uncomplicated Phase ends; move over to there. If the patient has died, the phase ends with the death of the patient. If the patient has died, do not report terminal values, e.g. those recorded after switching off life-support or heart rate "0" after death of the patient. Criteria of the Complicated Phase: * Need for oxygen supplementation (In patients with prior oxygen home therapy, clinically meaningful increase in need for oxygenation.) * paO2 at room air < 70 mmHg * SO2 at room air < 90 % * GOT or GPT > 5x ULN * New cardiac arrhythmia * New pericardial effusion >1cm * New heart failure with pulmonary edema, congestive hepatopathy or peripheral edema Remember: The Complicated Phase ends, if none of the criteria for the Complicated Phase is fulfilled anymore AND the patient is free of fever; then move to Recovery Phase. Also, as soon as one of the criteria of the Critical Phase are fulfilled, Complicated Phase ends; move over to Critical Phase. If the patient has died, the phase ends with the death of the patient. If the patient has died, do not report terminal values, e.g. those recorded after switching off life-support or heart rate "0" after death of the patient. Criteria of the Critical Phase: * Need for catecholamines * Life-threatening cardiac arrhythmia * Mechanical ventilation (invasive or non-invasive) * Liver failure with Quick< 50% * qSOFA >= 2 * Renal failure in need of dialysis Remember: The Critical Phase ends as soon as none of the criteria for the Critical Phase is fulfilled anymore AND the patient is free of fever. If the patient has died, it ends with the death of the patient. If the patient has died, do not report terminal values, i.e. those recorded after turning off life-support or heart rate "0" after death of the patient. Criteria of the Recovery Phase: *Improvement by at least one phase, i.e. Critical to Complicated or Complicated to Uncomplicated * Defervescence Remember: Uncomplicated asymptomatic patients enter recovery phase after 14 days of observation without disease progression No further progression or re-hospitalization If a text field can't be filled out, note 'ND' (for not determined).
Link
Trefwoorden
Versies (3)
- 02-07-21 02-07-21 - Sarah Riepenhausen
- 15-07-21 15-07-21 - Sarah Riepenhausen
- 16-07-21 16-07-21 - Sarah Riepenhausen
Houder van rechten
LEOSS
Geüploaded op
16 juli 2021
DOI
10.21961/mdm:42476
Licentie
Creative Commons BY 4.0
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LEOSS: Lean European Open Survey on SARS-CoV-2 Infected Patients
Emergency care details
- StudyEvent: Baseline
- StudyEvent: Comorbidities and Pre-medication
- StudyEvent: Phases
- StudyEvent: Therapeutics
- StudyEvent: Diagnostics
Beschrijving
Please select the initial therapeutic approaches performed in the emergency department to treat COVID-19
Alias
- UMLS CUI-1
- C0087111
- UMLS CUI-2
- C0205265
- UMLS CUI-3
- C0562508
- UMLS CUI-4
- C5203670
Beschrijving
Cardiopulmonary resuscitation
Datatype
boolean
Alias
- UMLS CUI [1]
- C0007203
Beschrijving
Drugs
Datatype
boolean
Alias
- UMLS CUI [1]
- C0013227
Beschrijving
Fluid administration
Datatype
boolean
Alias
- UMLS CUI [1]
- C0016286
Beschrijving
Inotropic support
Datatype
boolean
Alias
- UMLS CUI [1]
- C0304509
Beschrijving
Airway management
Datatype
boolean
Alias
- UMLS CUI [1]
- C0919655
- UMLS CUI [2]
- C0150126
- UMLS CUI [3]
- C0262756
Beschrijving
Other initial therapeutic approaches
Datatype
boolean
Alias
- UMLS CUI [1,1]
- C0087111
- UMLS CUI [1,2]
- C0205265
- UMLS CUI [1,3]
- C5203670
- UMLS CUI [1,4]
- C0205394
Beschrijving
Indicate other initial therapeutic approaches to treat COVID-19
Datatype
text
Alias
- UMLS CUI [1,1]
- C0087111
- UMLS CUI [1,2]
- C0205265
- UMLS CUI [1,3]
- C5203670
- UMLS CUI [1,4]
- C0205394
- UMLS CUI [1,5]
- C1521902
Beschrijving
Unknown initial therapeutic approaches
Datatype
boolean
Alias
- UMLS CUI [1,1]
- C0087111
- UMLS CUI [1,2]
- C0205265
- UMLS CUI [1,3]
- C5203670
- UMLS CUI [1,4]
- C0439673
Beschrijving
If respiratory / airway management in the emergency department please select
Alias
- UMLS CUI-1
- C0150126
- UMLS CUI-2
- C0035237
- UMLS CUI-3
- C0562508
Beschrijving
Oxygen inhalation
Datatype
boolean
Alias
- UMLS CUI [1]
- C0919655
Beschrijving
High-flow-O2
Datatype
boolean
Alias
- UMLS CUI [1]
- C1960097
- UMLS CUI [2]
- C4709666
Beschrijving
Non-invasive ventilation
Datatype
boolean
Alias
- UMLS CUI [1]
- C1997883
Beschrijving
Intubation and mechanical ventilation
Datatype
boolean
Alias
- UMLS CUI [1]
- C0021925
- UMLS CUI [2]
- C0199470
Beschrijving
No airway/respiratory management in the emergency department
Datatype
boolean
Alias
- UMLS CUI [1,1]
- C0150126
- UMLS CUI [1,2]
- C0562508
- UMLS CUI [1,3]
- C0549184
- UMLS CUI [2,1]
- C0035237
- UMLS CUI [2,2]
- C1273870
- UMLS CUI [2,3]
- C0562508
- UMLS CUI [2,4]
- C0549184
Beschrijving
Unknown respiratory / airway management in emergency department
Datatype
boolean
Alias
- UMLS CUI [1,1]
- C0150126
- UMLS CUI [1,2]
- C0562508
- UMLS CUI [1,3]
- C0439673
- UMLS CUI [2,1]
- C0035237
- UMLS CUI [2,2]
- C1273870
- UMLS CUI [2,3]
- C0562508
- UMLS CUI [2,4]
- C0439673
Beschrijving
If oxygen inhalation please select
Alias
- UMLS CUI-1
- C0919655
Beschrijving
Type of oxygen inhalation
Datatype
integer
Alias
- UMLS CUI [1,1]
- C0919655
- UMLS CUI [1,2]
- C0332307
Beschrijving
Indicate other type of oxygen inhalation
Datatype
text
Alias
- UMLS CUI [1,1]
- C0919655
- UMLS CUI [1,2]
- C0205394
- UMLS CUI [1,3]
- C1521902
Beschrijving
High flow nasal cannula (HFNC) details
Alias
- UMLS CUI-1
- C1960097
Beschrijving
Mechanical ventilation: ventilator settings
Alias
- UMLS CUI-1
- C0199470
- UMLS CUI-2
- C1318139
Beschrijving
CSV
Datatype
boolean
Alias
- UMLS CUI [1]
- C0412771
Beschrijving
CPAP
Datatype
boolean
Alias
- UMLS CUI [1]
- C0199451
Beschrijving
ASB
Datatype
boolean
Alias
- UMLS CUI [1]
- C0419003
Beschrijving
CPAP+ASB
Datatype
boolean
Alias
- UMLS CUI [1,1]
- C0199451
- UMLS CUI [1,2]
- C0419003
Beschrijving
BIPAP - SIMV
Datatype
boolean
Alias
- UMLS CUI [1,1]
- C1956423
- UMLS CUI [1,2]
- C0278335
Beschrijving
CMV - PCV
Datatype
boolean
Alias
- UMLS CUI [1,1]
- C2349743
- UMLS CUI [1,2]
- C0564626
Beschrijving
CMV - VCV
Datatype
boolean
Alias
- UMLS CUI [1,1]
- C2349743
- UMLS CUI [1,2]
- C1320708
Beschrijving
Mechanical ventilation not applicable
Datatype
boolean
Alias
- UMLS CUI [1,1]
- C1272460
- UMLS CUI [1,2]
- C0199470
Beschrijving
Unknown mechanical ventilation
Datatype
boolean
Alias
- UMLS CUI [1,1]
- C0199470
- UMLS CUI [1,2]
- C0439673
Beschrijving
BIPAP settings
Alias
- UMLS CUI-1
- C1956423
- UMLS CUI-2
- C1318139
Beschrijving
Level 1 BIPAP pressure setting
Datatype
float
Maateenheden
- mmHg
Alias
- UMLS CUI [1,1]
- C1956423
- UMLS CUI [1,2]
- C0033095
- UMLS CUI [1,3]
- C1318139
- UMLS CUI [1,4]
- C0456947
Beschrijving
Level 2 BIPAP pressure setting
Datatype
float
Maateenheden
- mmHg
Alias
- UMLS CUI [1,1]
- C1956423
- UMLS CUI [1,2]
- C0033095
- UMLS CUI [1,3]
- C1318139
- UMLS CUI [1,4]
- C0456948
Beschrijving
Mechanical ventilation: mean positive endexpiratory pressure (PEEP)
Alias
- UMLS CUI-1
- C0199470
- UMLS CUI-2
- C0032740
- UMLS CUI-3
- C0444504
Beschrijving
Mechanical ventilation: mean fraction of inspired oxygen (FIO2)
Alias
- UMLS CUI-1
- C0428167
- UMLS CUI-2
- C0199470
- UMLS CUI-3
- C0444504
Beschrijving
After the initial visit in the emergency department: Please provide further information concerning admission / discharge
Alias
- UMLS CUI-1
- C0030673
- UMLS CUI-2
- C0030685
- UMLS CUI-3
- C0562508
- UMLS CUI-4
- C1533716
Beschrijving
nformation concerning admission / discharge after emergency department visit
Datatype
integer
Alias
- UMLS CUI [1,1]
- C0030673
- UMLS CUI [1,2]
- C1533716
- UMLS CUI [1,3]
- C0687676
- UMLS CUI [1,4]
- C0562508
- UMLS CUI [2,1]
- C0030685
- UMLS CUI [2,2]
- C0562508
- UMLS CUI [2,3]
- C1533716
- UMLS CUI [2,4]
- C0687676
Beschrijving
Is data entry for this section finished?
Alias
- UMLS CUI-1
- C4684556
- UMLS CUI-2
- C1828479
- UMLS CUI-3
- C0205197
Similar models
Emergency care details
- StudyEvent: Baseline
- StudyEvent: Comorbidities and Pre-medication
- StudyEvent: Phases
- StudyEvent: Therapeutics
- StudyEvent: Diagnostics
C0562508 (UMLS CUI-2)
C1274040 (UMLS CUI-3)
C5203670 (UMLS CUI-4)
C0203463 (UMLS CUI [1,2])
C3846158 (UMLS CUI [1,2])
C0205200 (UMLS CUI [1,3])
C0521530 (UMLS CUI [1,2])
C0439064 (UMLS CUI [1,2])
C1522010 (UMLS CUI [1,3])
C1704711 (UMLS CUI [1,4])
C1704258 (UMLS CUI [1,5])
C0700321 (UMLS CUI [1,2])
C0221198 (UMLS CUI [1,3])
C0264545 (UMLS CUI [1,2])
C1274040 (UMLS CUI [1,2])
C0205394 (UMLS CUI [1,3])
C1274040 (UMLS CUI [1,2])
C0205394 (UMLS CUI [1,3])
C1521902 (UMLS CUI [1,4])
C1272696 (UMLS CUI [1,2])
C0439673 (UMLS CUI [1,2])
C0205265 (UMLS CUI-2)
C0562508 (UMLS CUI-3)
C5203670 (UMLS CUI-4)
C0150126 (UMLS CUI [2])
C0262756 (UMLS CUI [3])
C0205265 (UMLS CUI [1,2])
C5203670 (UMLS CUI [1,3])
C0205394 (UMLS CUI [1,4])
C0205265 (UMLS CUI [1,2])
C5203670 (UMLS CUI [1,3])
C0205394 (UMLS CUI [1,4])
C1521902 (UMLS CUI [1,5])
C0205265 (UMLS CUI [1,2])
C5203670 (UMLS CUI [1,3])
C0439673 (UMLS CUI [1,4])
C0035237 (UMLS CUI-2)
C0562508 (UMLS CUI-3)
C4709666 (UMLS CUI [2])
C0199470 (UMLS CUI [2])
C0562508 (UMLS CUI [1,2])
C0549184 (UMLS CUI [1,3])
C0035237 (UMLS CUI [2,1])
C1273870 (UMLS CUI [2,2])
C0562508 (UMLS CUI [2,3])
C0549184 (UMLS CUI [2,4])
C0562508 (UMLS CUI [1,2])
C0439673 (UMLS CUI [1,3])
C0035237 (UMLS CUI [2,1])
C1273870 (UMLS CUI [2,2])
C0562508 (UMLS CUI [2,3])
C0439673 (UMLS CUI [2,4])
C0332307 (UMLS CUI [1,2])
C0205394 (UMLS CUI [1,2])
C1521902 (UMLS CUI [1,3])
C1318139 (UMLS CUI-2)
C0419003 (UMLS CUI [1,2])
C0278335 (UMLS CUI [1,2])
C0564626 (UMLS CUI [1,2])
C1320708 (UMLS CUI [1,2])
C0199470 (UMLS CUI [1,2])
C0439673 (UMLS CUI [1,2])
C0033095 (UMLS CUI [1,2])
C1318139 (UMLS CUI [1,3])
C0456947 (UMLS CUI [1,4])
C0033095 (UMLS CUI [1,2])
C1318139 (UMLS CUI [1,3])
C0456948 (UMLS CUI [1,4])
C0032740 (UMLS CUI-2)
C0444504 (UMLS CUI-3)
C0032740 (UMLS CUI [1,2])
C0444504 (UMLS CUI [1,3])
C0199470 (UMLS CUI-2)
C0444504 (UMLS CUI-3)
C0199470 (UMLS CUI [1,2])
C0444504 (UMLS CUI [1,3])
C0030685 (UMLS CUI-2)
C0562508 (UMLS CUI-3)
C1533716 (UMLS CUI-4)
C1533716 (UMLS CUI [1,2])
C0687676 (UMLS CUI [1,3])
C0562508 (UMLS CUI [1,4])
C0030685 (UMLS CUI [2,1])
C0562508 (UMLS CUI [2,2])
C1533716 (UMLS CUI [2,3])
C0687676 (UMLS CUI [2,4])
C1828479 (UMLS CUI-2)
C0205197 (UMLS CUI-3)
C1828479 (UMLS CUI [1,2])
C0205197 (UMLS CUI [1,3])
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