ID
42476
Beschreibung
Study Title: LEOSS: Lean European Open Survey on SARS-CoV-2 Infected Patients https://leoss.net Study Indication: COVID-19 Date: 19.03.2021 Published with permission by Prof. Dr. med. J.-J. Vehreschild. LEOSS, a multi-center cohort study, has been created to get more in-depth knowledge about the epidemiology and clinical course of patients infected with SARS-CoV-2. Initiated by the ESCMID Emerging Infections Task Force (EITaF) and the German Infectious Disease Society, and supported by all German Centers for Health Research (DZG), LEOSS has developed into an international network of contributors. Via an integrative research approach with anonymous recruitment and collection of routine data in an open science context, LEOSS is building a uniform clinical dataset and providing real-time analyses. For more information feel free to explore https://leoss.net/. Please note that only cases with known outcome are collected! Baseline / diagnosis is defined as the day the sample of the first positive SARS-CoV-2 result was taken. Criteria of the Uncomplicated Phase: Asymptomatic OR Symptoms of upper respiratory tract infection and/or Nausea, emesis, diarrhea and/or Fever Remember: The Uncomplicated Phase ends, if a previously febrile patient has no fever anymore and has completed 14 days of follow-up without entering Complicated or Critical Phase; then move to Recovery Phase. Also, as soon as one of the criteria of the Complicated or Critical Phase are fulfilled, Uncomplicated Phase ends; move over to there. If the patient has died, the phase ends with the death of the patient. If the patient has died, do not report terminal values, e.g. those recorded after switching off life-support or heart rate "0" after death of the patient. Criteria of the Complicated Phase: * Need for oxygen supplementation (In patients with prior oxygen home therapy, clinically meaningful increase in need for oxygenation.) * paO2 at room air < 70 mmHg * SO2 at room air < 90 % * GOT or GPT > 5x ULN * New cardiac arrhythmia * New pericardial effusion >1cm * New heart failure with pulmonary edema, congestive hepatopathy or peripheral edema Remember: The Complicated Phase ends, if none of the criteria for the Complicated Phase is fulfilled anymore AND the patient is free of fever; then move to Recovery Phase. Also, as soon as one of the criteria of the Critical Phase are fulfilled, Complicated Phase ends; move over to Critical Phase. If the patient has died, the phase ends with the death of the patient. If the patient has died, do not report terminal values, e.g. those recorded after switching off life-support or heart rate "0" after death of the patient. Criteria of the Critical Phase: * Need for catecholamines * Life-threatening cardiac arrhythmia * Mechanical ventilation (invasive or non-invasive) * Liver failure with Quick< 50% * qSOFA >= 2 * Renal failure in need of dialysis Remember: The Critical Phase ends as soon as none of the criteria for the Critical Phase is fulfilled anymore AND the patient is free of fever. If the patient has died, it ends with the death of the patient. If the patient has died, do not report terminal values, i.e. those recorded after turning off life-support or heart rate "0" after death of the patient. Criteria of the Recovery Phase: *Improvement by at least one phase, i.e. Critical to Complicated or Complicated to Uncomplicated * Defervescence Remember: Uncomplicated asymptomatic patients enter recovery phase after 14 days of observation without disease progression No further progression or re-hospitalization If a text field can't be filled out, note 'ND' (for not determined).
Link
Stichworte
Versionen (3)
- 02.07.21 02.07.21 - Sarah Riepenhausen
- 15.07.21 15.07.21 - Sarah Riepenhausen
- 16.07.21 16.07.21 - Sarah Riepenhausen
Rechteinhaber
LEOSS
Hochgeladen am
16. Juli 2021
DOI
10.21961/mdm:42476
Lizenz
Creative Commons BY 4.0
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LEOSS: Lean European Open Survey on SARS-CoV-2 Infected Patients
Emergency care details
- StudyEvent: Baseline
- StudyEvent: Comorbidities and Pre-medication
- StudyEvent: Phases
- StudyEvent: Therapeutics
- StudyEvent: Diagnostics
Beschreibung
Please select the initial therapeutic approaches performed in the emergency department to treat COVID-19
Alias
- UMLS CUI-1
- C0087111
- UMLS CUI-2
- C0205265
- UMLS CUI-3
- C0562508
- UMLS CUI-4
- C5203670
Beschreibung
Cardiopulmonary resuscitation
Datentyp
boolean
Alias
- UMLS CUI [1]
- C0007203
Beschreibung
Drugs
Datentyp
boolean
Alias
- UMLS CUI [1]
- C0013227
Beschreibung
Fluid administration
Datentyp
boolean
Alias
- UMLS CUI [1]
- C0016286
Beschreibung
Inotropic support
Datentyp
boolean
Alias
- UMLS CUI [1]
- C0304509
Beschreibung
Airway management
Datentyp
boolean
Alias
- UMLS CUI [1]
- C0919655
- UMLS CUI [2]
- C0150126
- UMLS CUI [3]
- C0262756
Beschreibung
Other initial therapeutic approaches
Datentyp
boolean
Alias
- UMLS CUI [1,1]
- C0087111
- UMLS CUI [1,2]
- C0205265
- UMLS CUI [1,3]
- C5203670
- UMLS CUI [1,4]
- C0205394
Beschreibung
Indicate other initial therapeutic approaches to treat COVID-19
Datentyp
text
Alias
- UMLS CUI [1,1]
- C0087111
- UMLS CUI [1,2]
- C0205265
- UMLS CUI [1,3]
- C5203670
- UMLS CUI [1,4]
- C0205394
- UMLS CUI [1,5]
- C1521902
Beschreibung
Unknown initial therapeutic approaches
Datentyp
boolean
Alias
- UMLS CUI [1,1]
- C0087111
- UMLS CUI [1,2]
- C0205265
- UMLS CUI [1,3]
- C5203670
- UMLS CUI [1,4]
- C0439673
Beschreibung
If respiratory / airway management in the emergency department please select
Alias
- UMLS CUI-1
- C0150126
- UMLS CUI-2
- C0035237
- UMLS CUI-3
- C0562508
Beschreibung
Oxygen inhalation
Datentyp
boolean
Alias
- UMLS CUI [1]
- C0919655
Beschreibung
High-flow-O2
Datentyp
boolean
Alias
- UMLS CUI [1]
- C1960097
- UMLS CUI [2]
- C4709666
Beschreibung
Non-invasive ventilation
Datentyp
boolean
Alias
- UMLS CUI [1]
- C1997883
Beschreibung
Intubation and mechanical ventilation
Datentyp
boolean
Alias
- UMLS CUI [1]
- C0021925
- UMLS CUI [2]
- C0199470
Beschreibung
No airway/respiratory management in the emergency department
Datentyp
boolean
Alias
- UMLS CUI [1,1]
- C0150126
- UMLS CUI [1,2]
- C0562508
- UMLS CUI [1,3]
- C0549184
- UMLS CUI [2,1]
- C0035237
- UMLS CUI [2,2]
- C1273870
- UMLS CUI [2,3]
- C0562508
- UMLS CUI [2,4]
- C0549184
Beschreibung
Unknown respiratory / airway management in emergency department
Datentyp
boolean
Alias
- UMLS CUI [1,1]
- C0150126
- UMLS CUI [1,2]
- C0562508
- UMLS CUI [1,3]
- C0439673
- UMLS CUI [2,1]
- C0035237
- UMLS CUI [2,2]
- C1273870
- UMLS CUI [2,3]
- C0562508
- UMLS CUI [2,4]
- C0439673
Beschreibung
If oxygen inhalation please select
Alias
- UMLS CUI-1
- C0919655
Beschreibung
Type of oxygen inhalation
Datentyp
integer
Alias
- UMLS CUI [1,1]
- C0919655
- UMLS CUI [1,2]
- C0332307
Beschreibung
Indicate other type of oxygen inhalation
Datentyp
text
Alias
- UMLS CUI [1,1]
- C0919655
- UMLS CUI [1,2]
- C0205394
- UMLS CUI [1,3]
- C1521902
Beschreibung
High flow nasal cannula (HFNC) details
Alias
- UMLS CUI-1
- C1960097
Beschreibung
Mechanical ventilation: ventilator settings
Alias
- UMLS CUI-1
- C0199470
- UMLS CUI-2
- C1318139
Beschreibung
CSV
Datentyp
boolean
Alias
- UMLS CUI [1]
- C0412771
Beschreibung
CPAP
Datentyp
boolean
Alias
- UMLS CUI [1]
- C0199451
Beschreibung
ASB
Datentyp
boolean
Alias
- UMLS CUI [1]
- C0419003
Beschreibung
CPAP+ASB
Datentyp
boolean
Alias
- UMLS CUI [1,1]
- C0199451
- UMLS CUI [1,2]
- C0419003
Beschreibung
BIPAP - SIMV
Datentyp
boolean
Alias
- UMLS CUI [1,1]
- C1956423
- UMLS CUI [1,2]
- C0278335
Beschreibung
CMV - PCV
Datentyp
boolean
Alias
- UMLS CUI [1,1]
- C2349743
- UMLS CUI [1,2]
- C0564626
Beschreibung
CMV - VCV
Datentyp
boolean
Alias
- UMLS CUI [1,1]
- C2349743
- UMLS CUI [1,2]
- C1320708
Beschreibung
Mechanical ventilation not applicable
Datentyp
boolean
Alias
- UMLS CUI [1,1]
- C1272460
- UMLS CUI [1,2]
- C0199470
Beschreibung
Unknown mechanical ventilation
Datentyp
boolean
Alias
- UMLS CUI [1,1]
- C0199470
- UMLS CUI [1,2]
- C0439673
Beschreibung
BIPAP settings
Alias
- UMLS CUI-1
- C1956423
- UMLS CUI-2
- C1318139
Beschreibung
Level 1 BIPAP pressure setting
Datentyp
float
Maßeinheiten
- mmHg
Alias
- UMLS CUI [1,1]
- C1956423
- UMLS CUI [1,2]
- C0033095
- UMLS CUI [1,3]
- C1318139
- UMLS CUI [1,4]
- C0456947
Beschreibung
Level 2 BIPAP pressure setting
Datentyp
float
Maßeinheiten
- mmHg
Alias
- UMLS CUI [1,1]
- C1956423
- UMLS CUI [1,2]
- C0033095
- UMLS CUI [1,3]
- C1318139
- UMLS CUI [1,4]
- C0456948
Beschreibung
Mechanical ventilation: mean positive endexpiratory pressure (PEEP)
Alias
- UMLS CUI-1
- C0199470
- UMLS CUI-2
- C0032740
- UMLS CUI-3
- C0444504
Beschreibung
Mechanical ventilation: mean fraction of inspired oxygen (FIO2)
Alias
- UMLS CUI-1
- C0428167
- UMLS CUI-2
- C0199470
- UMLS CUI-3
- C0444504
Beschreibung
After the initial visit in the emergency department: Please provide further information concerning admission / discharge
Alias
- UMLS CUI-1
- C0030673
- UMLS CUI-2
- C0030685
- UMLS CUI-3
- C0562508
- UMLS CUI-4
- C1533716
Beschreibung
nformation concerning admission / discharge after emergency department visit
Datentyp
integer
Alias
- UMLS CUI [1,1]
- C0030673
- UMLS CUI [1,2]
- C1533716
- UMLS CUI [1,3]
- C0687676
- UMLS CUI [1,4]
- C0562508
- UMLS CUI [2,1]
- C0030685
- UMLS CUI [2,2]
- C0562508
- UMLS CUI [2,3]
- C1533716
- UMLS CUI [2,4]
- C0687676
Beschreibung
Is data entry for this section finished?
Alias
- UMLS CUI-1
- C4684556
- UMLS CUI-2
- C1828479
- UMLS CUI-3
- C0205197
Ähnliche Modelle
Emergency care details
- StudyEvent: Baseline
- StudyEvent: Comorbidities and Pre-medication
- StudyEvent: Phases
- StudyEvent: Therapeutics
- StudyEvent: Diagnostics
C0562508 (UMLS CUI-2)
C1274040 (UMLS CUI-3)
C5203670 (UMLS CUI-4)
C0203463 (UMLS CUI [1,2])
C3846158 (UMLS CUI [1,2])
C0205200 (UMLS CUI [1,3])
C0521530 (UMLS CUI [1,2])
C0439064 (UMLS CUI [1,2])
C1522010 (UMLS CUI [1,3])
C1704711 (UMLS CUI [1,4])
C1704258 (UMLS CUI [1,5])
C0700321 (UMLS CUI [1,2])
C0221198 (UMLS CUI [1,3])
C0264545 (UMLS CUI [1,2])
C1274040 (UMLS CUI [1,2])
C0205394 (UMLS CUI [1,3])
C1274040 (UMLS CUI [1,2])
C0205394 (UMLS CUI [1,3])
C1521902 (UMLS CUI [1,4])
C1272696 (UMLS CUI [1,2])
C0439673 (UMLS CUI [1,2])
C0205265 (UMLS CUI-2)
C0562508 (UMLS CUI-3)
C5203670 (UMLS CUI-4)
C0150126 (UMLS CUI [2])
C0262756 (UMLS CUI [3])
C0205265 (UMLS CUI [1,2])
C5203670 (UMLS CUI [1,3])
C0205394 (UMLS CUI [1,4])
C0205265 (UMLS CUI [1,2])
C5203670 (UMLS CUI [1,3])
C0205394 (UMLS CUI [1,4])
C1521902 (UMLS CUI [1,5])
C0205265 (UMLS CUI [1,2])
C5203670 (UMLS CUI [1,3])
C0439673 (UMLS CUI [1,4])
C0035237 (UMLS CUI-2)
C0562508 (UMLS CUI-3)
C4709666 (UMLS CUI [2])
C0199470 (UMLS CUI [2])
C0562508 (UMLS CUI [1,2])
C0549184 (UMLS CUI [1,3])
C0035237 (UMLS CUI [2,1])
C1273870 (UMLS CUI [2,2])
C0562508 (UMLS CUI [2,3])
C0549184 (UMLS CUI [2,4])
C0562508 (UMLS CUI [1,2])
C0439673 (UMLS CUI [1,3])
C0035237 (UMLS CUI [2,1])
C1273870 (UMLS CUI [2,2])
C0562508 (UMLS CUI [2,3])
C0439673 (UMLS CUI [2,4])
C0332307 (UMLS CUI [1,2])
C0205394 (UMLS CUI [1,2])
C1521902 (UMLS CUI [1,3])
C1318139 (UMLS CUI-2)
C0419003 (UMLS CUI [1,2])
C0278335 (UMLS CUI [1,2])
C0564626 (UMLS CUI [1,2])
C1320708 (UMLS CUI [1,2])
C0199470 (UMLS CUI [1,2])
C0439673 (UMLS CUI [1,2])
C0033095 (UMLS CUI [1,2])
C1318139 (UMLS CUI [1,3])
C0456947 (UMLS CUI [1,4])
C0033095 (UMLS CUI [1,2])
C1318139 (UMLS CUI [1,3])
C0456948 (UMLS CUI [1,4])
C0032740 (UMLS CUI-2)
C0444504 (UMLS CUI-3)
C0032740 (UMLS CUI [1,2])
C0444504 (UMLS CUI [1,3])
C0199470 (UMLS CUI-2)
C0444504 (UMLS CUI-3)
C0199470 (UMLS CUI [1,2])
C0444504 (UMLS CUI [1,3])
C0030685 (UMLS CUI-2)
C0562508 (UMLS CUI-3)
C1533716 (UMLS CUI-4)
C1533716 (UMLS CUI [1,2])
C0687676 (UMLS CUI [1,3])
C0562508 (UMLS CUI [1,4])
C0030685 (UMLS CUI [2,1])
C0562508 (UMLS CUI [2,2])
C1533716 (UMLS CUI [2,3])
C0687676 (UMLS CUI [2,4])
C1828479 (UMLS CUI-2)
C0205197 (UMLS CUI-3)
C1828479 (UMLS CUI [1,2])
C0205197 (UMLS CUI [1,3])
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