ID

42476

Description

Study Title: LEOSS: Lean European Open Survey on SARS-CoV-2 Infected Patients https://leoss.net Study Indication: COVID-19 Date: 19.03.2021 Published with permission by Prof. Dr. med. J.-J. Vehreschild. LEOSS, a multi-center cohort study, has been created to get more in-depth knowledge about the epidemiology and clinical course of patients infected with SARS-CoV-2. Initiated by the ESCMID Emerging Infections Task Force (EITaF) and the German Infectious Disease Society, and supported by all German Centers for Health Research (DZG), LEOSS has developed into an international network of contributors. Via an integrative research approach with anonymous recruitment and collection of routine data in an open science context, LEOSS is building a uniform clinical dataset and providing real-time analyses. For more information feel free to explore https://leoss.net/. Please note that only cases with known outcome are collected! Baseline / diagnosis is defined as the day the sample of the first positive SARS-CoV-2 result was taken. Criteria of the Uncomplicated Phase: Asymptomatic OR Symptoms of upper respiratory tract infection and/or Nausea, emesis, diarrhea and/or Fever Remember: The Uncomplicated Phase ends, if a previously febrile patient has no fever anymore and has completed 14 days of follow-up without entering Complicated or Critical Phase; then move to Recovery Phase. Also, as soon as one of the criteria of the Complicated or Critical Phase are fulfilled, Uncomplicated Phase ends; move over to there. If the patient has died, the phase ends with the death of the patient. If the patient has died, do not report terminal values, e.g. those recorded after switching off life-support or heart rate "0" after death of the patient. Criteria of the Complicated Phase: * Need for oxygen supplementation (In patients with prior oxygen home therapy, clinically meaningful increase in need for oxygenation.) * paO2 at room air < 70 mmHg * SO2 at room air < 90 % * GOT or GPT > 5x ULN * New cardiac arrhythmia * New pericardial effusion >1cm * New heart failure with pulmonary edema, congestive hepatopathy or peripheral edema Remember: The Complicated Phase ends, if none of the criteria for the Complicated Phase is fulfilled anymore AND the patient is free of fever; then move to Recovery Phase. Also, as soon as one of the criteria of the Critical Phase are fulfilled, Complicated Phase ends; move over to Critical Phase. If the patient has died, the phase ends with the death of the patient. If the patient has died, do not report terminal values, e.g. those recorded after switching off life-support or heart rate "0" after death of the patient. Criteria of the Critical Phase: * Need for catecholamines * Life-threatening cardiac arrhythmia * Mechanical ventilation (invasive or non-invasive) * Liver failure with Quick< 50% * qSOFA >= 2 * Renal failure in need of dialysis Remember: The Critical Phase ends as soon as none of the criteria for the Critical Phase is fulfilled anymore AND the patient is free of fever. If the patient has died, it ends with the death of the patient. If the patient has died, do not report terminal values, i.e. those recorded after turning off life-support or heart rate "0" after death of the patient. Criteria of the Recovery Phase: *Improvement by at least one phase, i.e. Critical to Complicated or Complicated to Uncomplicated * Defervescence Remember: Uncomplicated asymptomatic patients enter recovery phase after 14 days of observation without disease progression No further progression or re-hospitalization If a text field can't be filled out, note 'ND' (for not determined).

Link

https://leoss.net

Keywords

  1. 7/2/21 7/2/21 - Sarah Riepenhausen
  2. 7/15/21 7/15/21 - Sarah Riepenhausen
  3. 7/16/21 7/16/21 - Sarah Riepenhausen
Copyright Holder

LEOSS

Uploaded on

July 16, 2021

DOI

10.21961/mdm:42476

License

Creative Commons BY 4.0

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LEOSS: Lean European Open Survey on SARS-CoV-2 Infected Patients

Complicated Phase

Symptoms / findings of complicated phase:
Description

Symptoms / findings of complicated phase:

Alias
UMLS CUI-1
C0243095
UMLS CUI-2
C1457887
UMLS CUI-3
C0231242
UMLS CUI-4
C0205390
paO2 at room air < 70 mmHg
Description

CO (paO2 at room air)

Data type

boolean

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0202155
UMLS CUI [1,4]
C2709070
SO2 at room air < 90 mmHg
Description

CO (SO2 at room air)

Data type

boolean

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0523807
UMLS CUI [1,4]
C2709070
AST or ALT > 5x ULN
Description

CO (AST | ALT)

Data type

boolean

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0201899
UMLS CUI [2,1]
C0231242
UMLS CUI [2,2]
C0205390
UMLS CUI [2,3]
C0201836
New cardiac arrhythmia
Description

CO (New cardiac arrhythmia)

Data type

boolean

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0003811
UMLS CUI [1,4]
C0205314
New pericardial effusion >1cm
Description

CO (New pericardial effusion)

Data type

boolean

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0031039
UMLS CUI [1,4]
C0205314
New heart failure with pulmonary edema, congestive hepatopathy or peripheral edema
Description

CO (New heart failure with pulmonary edema, congestive hepatopathy or peripheral edema)

Data type

boolean

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0205314
UMLS CUI [1,4]
C0018801
UMLS CUI [1,5]
C0034063
UMLS CUI [2,1]
C0231242
UMLS CUI [2,2]
C0205390
UMLS CUI [2,3]
C0205314
UMLS CUI [2,4]
C0018801
UMLS CUI [2,5]
C0085649
UMLS CUI [3,1]
C0231242
UMLS CUI [3,2]
C0205390
UMLS CUI [3,3]
C0205314
UMLS CUI [3,4]
C0018801
UMLS CUI [3,5]
C0023895
Need for oxygen supplementation (based on clinical impression or test results)
Description

CO (Need for oxygen supplementation, based on clinical impression or test result)

Data type

boolean

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0686904
UMLS CUI [1,4]
C0919655
UMLS CUI [1,5]
C2973287
UMLS CUI [2,1]
C0231242
UMLS CUI [2,2]
C0205390
UMLS CUI [2,3]
C0686904
UMLS CUI [2,4]
C0919655
UMLS CUI [2,5]
C0456984
Clinically meaningful increase of prior oxygen home therapy
Description

CO (Increase of prior oxygen home therapy)

Data type

boolean

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0421203
UMLS CUI [1,4]
C1514463
UMLS CUI [1,5]
C0442805
Complicated phase: Feeling of breathlessness
Description

Complicated phase: Feeling of breathlessness

Alias
UMLS CUI-1
C0231242
UMLS CUI-2
C0205390
UMLS CUI-3
C0013404
Feeling of breathlessness
Description

CO (Breathlessness)

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0013404
Complicated phase: Fever
Description

Complicated phase: Fever

Alias
UMLS CUI-1
C0231242
UMLS CUI-2
C0205390
UMLS CUI-3
C0015967
Complicated phase: Duration of fever
Description

You have indicated fever as a symptom or increased temperature in this phase, please indicate the duration only for this phase (the duration of fever cannot exceed the duration of the phase).

Data type

integer

Measurement units
  • days
Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0015967
UMLS CUI [1,4]
C0449238
Complicated phase: Vital signs
Description

Complicated phase: Vital signs

Alias
UMLS CUI-1
C0231242
UMLS CUI-2
C0205390
UMLS CUI-3
C0518766
Systolic BP in CO
Description

Indicate worst value. Worst means farthest from normal range.

Data type

integer

Alias
UMLS CUI [1,1]
C0871470
UMLS CUI [1,2]
C1522166
UMLS CUI [1,3]
C0231242
UMLS CUI [1,4]
C0205390
Diastolic BP in CO
Description

Indicate worst value. Worst means farthest from normal range.

Data type

integer

Alias
UMLS CUI [1,1]
C0428883
UMLS CUI [1,2]
C1522166
UMLS CUI [1,3]
C0231242
UMLS CUI [1,4]
C0205390
Pulse in CO
Description

Indicate worst value. Worst means farthest from normal range.

Data type

integer

Alias
UMLS CUI [1,1]
C0232117
UMLS CUI [1,2]
C1522166
UMLS CUI [1,3]
C0231242
UMLS CUI [1,4]
C0205390
SO2 in CO
Description

Indicate worst value. Worst means farthest from normal range.

Data type

integer

Alias
UMLS CUI [1,1]
C0523807
UMLS CUI [1,2]
C1522166
UMLS CUI [1,3]
C0231242
UMLS CUI [1,4]
C0205390
paO2 in CO
Description

Indicate worst value. Worst means farthest from normal range.

Data type

integer

Alias
UMLS CUI [1,1]
C0202155
UMLS CUI [1,2]
C1522166
UMLS CUI [1,3]
C0231242
UMLS CUI [1,4]
C0205390
paCO2 in CO
Description

Indicate worst value. Worst means farthest from normal range.

Data type

integer

Alias
UMLS CUI [1,1]
C1822070
UMLS CUI [1,2]
C1522166
UMLS CUI [1,3]
C0231242
UMLS CUI [1,4]
C0205390
Temperature in CO
Description

Indicate worst value. Worst means farthest from normal range.

Data type

integer

Alias
UMLS CUI [1,1]
C0039476
UMLS CUI [1,2]
C1522166
UMLS CUI [1,3]
C0231242
UMLS CUI [1,4]
C0205390
Respiratory rate / minute in CO
Description

Indicate worst value. Worst means farthest from normal range.

Data type

integer

Alias
UMLS CUI [1,1]
C0231832
UMLS CUI [1,2]
C1522166
UMLS CUI [1,3]
C0231242
UMLS CUI [1,4]
C0205390
Glasgow Coma scale (GCS) in CO
Description

Indicate worst value. Worst means farthest from normal range.

Data type

integer

Alias
UMLS CUI [1,1]
C0017594
UMLS CUI [1,2]
C1522166
UMLS CUI [1,3]
C0231242
UMLS CUI [1,4]
C0205390
Complicated phase: Lung ultrasound
Description

Complicated phase: Lung ultrasound

Alias
UMLS CUI-1
C0231242
UMLS CUI-2
C0205390
UMLS CUI-3
C0203463
B lines (multifocal, discrete or confluent)
Description

Indicate worst results from all ultrasounds during this phase of disease.

Data type

boolean

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0203463
UMLS CUI [1,4]
C1522166
UMLS CUI [1,5]
C3846158
Confluent B lines
Description

Indicate worst results from all ultrasounds during this phase of disease.

Data type

boolean

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0203463
UMLS CUI [1,4]
C1522166
UMLS CUI [1,5]
C3846158
UMLS CUI [1,6]
C0205200
Consolidation (non translobar and translobar)
Description

Indicate worst results from all ultrasounds during this phase of disease.

Data type

boolean

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0203463
UMLS CUI [1,4]
C1522166
UMLS CUI [1,5]
C0521530
Multilobar distribution of abnormalities
Description

Indicate worst results from all ultrasounds during this phase of disease.

Data type

boolean

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0203463
UMLS CUI [1,4]
C1522166
UMLS CUI [1,5]
C0439064
UMLS CUI [1,6]
C1522010
UMLS CUI [1,7]
C1704711
UMLS CUI [1,8]
C1704258
Small (centomeric) lesions
Description

Indicate worst results from all ultrasounds during this phase of disease.

Data type

boolean

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0203463
UMLS CUI [1,4]
C1522166
UMLS CUI [1,5]
C0700321
UMLS CUI [1,6]
C0221198
Thickened pleural line
Description

Indicate worst results from all ultrasounds during this phase of disease.

Data type

boolean

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0203463
UMLS CUI [1,4]
C1522166
UMLS CUI [1,5]
C0264545
Other lung ultrasound results
Description

CO (Other lung ultrasound result)

Data type

boolean

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0203463
UMLS CUI [1,4]
C0205394
UMLS CUI [1,5]
C1274040
Indicate other lung ultrasound results
Description

CO (indicate other lung ultrasound results)

Data type

text

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0203463
UMLS CUI [1,4]
C0205394
UMLS CUI [1,5]
C1274040
UMLS CUI [1,6]
C1521902
No abnormal findings
Description

CO (lung ultrasound, no abnormal findings)

Data type

boolean

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0203463
UMLS CUI [1,4]
C1704258
UMLS CUI [1,5]
C0549184
Not done
Description

CO (lung ultrasound, not done)

Data type

boolean

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0203463
UMLS CUI [1,4]
C1272696
Unknown
Description

CO (lung ultrasound, unknown)

Data type

boolean

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0203463
UMLS CUI [1,4]
C0439673
Complicated phase: Chest CT results
Description

Complicated phase: Chest CT results

Alias
UMLS CUI-1
C0231242
UMLS CUI-2
C0205390
UMLS CUI-3
C0202823
UMLS CUI-4
C1522166
UMLS CUI-5
C1274040
Air trapping
Description

Worst results from all CTs during this phase of disease.

Data type

boolean

Alias
UMLS CUI [1,1]
C0231819
UMLS CUI [1,2]
C0202823
UMLS CUI [1,3]
C1522166
UMLS CUI [1,4]
C0231242
UMLS CUI [1,5]
C0205390
Areas of consolidation
Description

Worst results from all CTs during this phase of disease.

Data type

boolean

Alias
UMLS CUI [1,1]
C0521530
UMLS CUI [1,2]
C0202823
UMLS CUI [1,3]
C1522166
UMLS CUI [1,4]
C0231242
UMLS CUI [1,5]
C0205390
Bronchiolitis
Description

Worst results from all CTs during this phase of disease.

Data type

boolean

Alias
UMLS CUI [1,1]
C0006271
UMLS CUI [1,2]
C0202823
UMLS CUI [1,3]
C1522166
UMLS CUI [1,4]
C0231242
UMLS CUI [1,5]
C0205390
Crazy paving pattern
Description

Worst results from all CTs during this phase of disease.

Data type

boolean

Alias
UMLS CUI [1,1]
C4476749
UMLS CUI [1,2]
C1522166
UMLS CUI [1,3]
C0231242
UMLS CUI [1,4]
C0205390
Ground glass opacities
Description

Worst results from all CTs during this phase of disease.

Data type

boolean

Alias
UMLS CUI [1,1]
C3827002
UMLS CUI [1,2]
C0202823
UMLS CUI [1,3]
C1522166
UMLS CUI [1,4]
C0231242
UMLS CUI [1,5]
C0205390
Interlobular septal thickening
Description

Worst results from all CTs during this phase of disease.

Data type

boolean

Alias
UMLS CUI [1,1]
C4280727
UMLS CUI [1,2]
C1522166
UMLS CUI [1,3]
C0231242
UMLS CUI [1,4]
C0205390
Nodulary lesions
Description

Worst results from all CTs during this phase of disease.

Data type

boolean

Alias
UMLS CUI [1,1]
C1518345
UMLS CUI [1,2]
C0202823
UMLS CUI [1,3]
C1522166
UMLS CUI [1,4]
C0231242
UMLS CUI [1,5]
C0205390
Pleural effusion
Description

Worst results from all CTs during this phase of disease.

Data type

boolean

Alias
UMLS CUI [1,1]
C0032227
UMLS CUI [1,2]
C0202823
UMLS CUI [1,3]
C1522166
UMLS CUI [1,4]
C0231242
UMLS CUI [1,5]
C0205390
Chest x-ray results
Description

CO (Chest x-ray)

Data type

boolean

Alias
UMLS CUI [1,1]
C0039985
UMLS CUI [1,2]
C0231242
UMLS CUI [1,3]
C0205390
Indicate chest x-ray results
Description

CO (indicate chest x-ray result)

Data type

text

Alias
UMLS CUI [1,1]
C0039985
UMLS CUI [1,2]
C1274040
UMLS CUI [1,3]
C0231242
UMLS CUI [1,4]
C0205390
Other relevant chest CT results
Description

CO (Other relevant CT results)

Data type

boolean

Alias
UMLS CUI [1,1]
C0205394
UMLS CUI [1,2]
C1274040
UMLS CUI [1,3]
C2347946
UMLS CUI [1,4]
C0202823
UMLS CUI [1,5]
C0231242
UMLS CUI [1,6]
C0205390
Indicate other relevant chest CT results
Description

CO (indicate other relevant CT results)

Data type

text

Alias
UMLS CUI [1,1]
C0205394
UMLS CUI [1,2]
C1274040
UMLS CUI [1,3]
C2347946
UMLS CUI [1,4]
C1521902
UMLS CUI [1,5]
C0202823
UMLS CUI [1,6]
C0231242
UMLS CUI [1,7]
C0205390
Normal CT
Description

CO (Normal CT)

Data type

boolean

Alias
UMLS CUI [1,1]
C0205307
UMLS CUI [1,2]
C0202823
UMLS CUI [1,3]
C0231242
UMLS CUI [1,4]
C0205390
Not done
Description

CO (chest CT not done)

Data type

boolean

Alias
UMLS CUI [1,1]
C1272696
UMLS CUI [1,2]
C0202823
UMLS CUI [1,3]
C0231242
UMLS CUI [1,4]
C0205390
Complicated phase: Treatments received, Antivirals
Description

Complicated phase: Treatments received, Antivirals

Alias
UMLS CUI-1
C0231242
UMLS CUI-2
C0205390
UMLS CUI-3
C0280274
Atazanavir
Description

All drugs in the context of the SARS-CoV-2 infection and administered at least once during this phase of disease.

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C1145759
Darunavir
Description

All drugs in the context of the SARS-CoV-2 infection and administered at least once during this phase of disease.

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C1435444
Chloroquine phosphate
Description

All drugs in the context of the SARS-CoV-2 infection and administered at least once during this phase of disease.

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0280274
UMLS CUI [1,4]
C0055447
Hydroxychloroquine
Description

All drugs in the context of the SARS-CoV-2 infection and administered at least once during this phase of disease.

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0280274
UMLS CUI [1,4]
C0020336
Ivermectin
Description

All drugs in the context of the SARS-CoV-2 infection and administered at least once during this phase of disease.

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0280274
UMLS CUI [1,4]
C0022322
Lopinavir/ritonavir
Description

All drugs in the context of the SARS-CoV-2 infection and administered at least once during this phase of disease.

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0674432
UMLS CUI [2,1]
C0231242
UMLS CUI [2,2]
C0205390
UMLS CUI [2,3]
C0292818
Maraviroc
Description

All drugs in the context of the SARS-CoV-2 infection and administered at least once during this phase of disease.

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C1667052
Ganciclovir
Description

All drugs in the context of the SARS-CoV-2 infection and administered at least once during this phase of disease.

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0017066
Oseltamivir
Description

All drugs in the context of the SARS-CoV-2 infection and administered at least once during this phase of disease.

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0874161
Remdesivir
Description

All drugs in the context of the SARS-CoV-2 infection and administered at least once during this phase of disease.

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C4726677
Ribavirin
Description

All drugs in the context of the SARS-CoV-2 infection and administered at least once during this phase of disease.

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0035525
Camostat
Description

All drugs in the context of the SARS-CoV-2 infection and administered at least once during this phase of disease.

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0280274
UMLS CUI [1,4]
C0129975
Favipiravir
Description

All drugs in the context of the SARS-CoV-2 infection and administered at least once during this phase of disease.

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C1138226
Monoclonal antibody therapy (e.g. Bamlanivimab, REGN-COV-2)
Description

CO (Monoclonal antibody therapy, e.g. Bamlanivimab, REGN-COV-2)

Data type

boolean

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0279694
UMLS CUI [1,4]
C0280274
UMLS CUI [2]
C5421805
UMLS CUI [3]
C5389881
Complicated phase: Treatments received, Antibiotics
Description

Complicated phase: Treatments received, Antibiotics

Alias
UMLS CUI-1
C0003232
UMLS CUI-2
C0231242
UMLS CUI-3
C0205390
Betalactams (penicillins, cephalosporines, carbapenems)
Description

All drugs in the context of the SARS-CoV-2 infection and administered at least once during this phase of disease.

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0282215
UMLS CUI [2,1]
C0231242
UMLS CUI [2,2]
C0205390
UMLS CUI [2,3]
C0006968
UMLS CUI [3,1]
C0231242
UMLS CUI [3,2]
C0205390
UMLS CUI [3,3]
C0030842
UMLS CUI [4,1]
C0231242
UMLS CUI [4,2]
C0205390
UMLS CUI [4,3]
C3536856
Azithromycin
Description

All drugs in the context of the SARS-CoV-2 infection and administered at least once during this phase of disease.

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0052796
Other macrolide (erythromycin, clarithromycin, roxithromycin)
Description

All drugs in the context of the SARS-CoV-2 infection and administered at least once during this phase of disease.

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0282563
UMLS CUI [1,4]
C0205394
UMLS CUI [2,1]
C0231242
UMLS CUI [2,2]
C0205390
UMLS CUI [2,3]
C0035891
UMLS CUI [3,1]
C0231242
UMLS CUI [3,2]
C0205390
UMLS CUI [3,3]
C0014806
UMLS CUI [4,1]
C0231242
UMLS CUI [4,2]
C0205390
UMLS CUI [4,3]
C0055856
Fluorochinolones (ciprofloxacin, moxifloxacin, levofloxacin)
Description

All drugs in the context of the SARS-CoV-2 infection and administered at least once during this phase of disease.

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0949665
UMLS CUI [2,1]
C0231242
UMLS CUI [2,2]
C0205390
UMLS CUI [2,3]
C0282386
UMLS CUI [3,1]
C0231242
UMLS CUI [3,2]
C0205390
UMLS CUI [3,3]
C0536495
UMLS CUI [4,1]
C0231242
UMLS CUI [4,2]
C0205390
UMLS CUI [4,3]
C0008809
Complicated phase: Treatments received, Antifungals
Description

Complicated phase: Treatments received, Antifungals

Alias
UMLS CUI-1
C0231242
UMLS CUI-2
C0205390
UMLS CUI-3
C0003308
Itraconazole
Description

All drugs in the context of the SARS-CoV-2 infection and administered at least once during this phase of disease.

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0064113
Posaconazole
Description

All drugs in the context of the SARS-CoV-2 infection and administered at least once during this phase of disease.

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0936148
Other systemically active antifungals
Description

All drugs in the context of the SARS-CoV-2 infection and administered at least once during this phase of disease.

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0003308
UMLS CUI [1,4]
C0205394
UMLS CUI [1,5]
C1515119
Treatments received, Immunomodulators
Description

Treatments received, Immunomodulators

Alias
UMLS CUI-1
C0231242
UMLS CUI-2
C0205390
UMLS CUI-3
C1527392
Steroids > 0.5 mg/kg prednisone equivalents
Description

All drugs in the context of the SARS-CoV-2 infection and administered at least once during this phase of disease.

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0038317
UMLS CUI [1,4]
C0444956
Steroids <= 0.5 mg/kg prednisone equivalents
Description

All drugs in the context of the SARS-CoV-2 infection and administered at least once during this phase of disease.

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0038317
UMLS CUI [1,4]
C0445550
IL-6-receptor antagonist (tocilizumab)
Description

All drugs in the context of the SARS-CoV-2 infection and administered at least once during this phase of disease.

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C3819026
UMLS CUI [2,1]
C0231242
UMLS CUI [2,2]
C0205390
UMLS CUI [2,3]
C1609165
CNI or mTor inhibitors (e.g. cyclosporin A, tacrolimus, sirolimus, everolimus)
Description

All drugs in the context of the SARS-CoV-2 infection and administered at least once during this phase of disease.

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C1562036
UMLS CUI [2,1]
C0231242
UMLS CUI [2,2]
C0205390
UMLS CUI [2,3]
C2746052
UMLS CUI [3,1]
C0231242
UMLS CUI [3,2]
C0205390
UMLS CUI [3,3]
C0541315
UMLS CUI [4,1]
C0231242
UMLS CUI [4,2]
C0205390
UMLS CUI [4,3]
C0072980
UMLS CUI [5,1]
C0231242
UMLS CUI [5,2]
C0205390
UMLS CUI [5,3]
C0010592
UMLS CUI [6,1]
C0231242
UMLS CUI [6,2]
C0205390
UMLS CUI [6,3]
C0085149
Anti-TNF-alpha inhibitors (e.g. adalimumab, etanercept)
Description

All drugs in the context of the SARS-CoV-2 infection and administered at least once during this phase of disease.

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C3653350
UMLS CUI [2,1]
C0231242
UMLS CUI [2,2]
C0205390
UMLS CUI [2,3]
C1122087
UMLS CUI [3,1]
C0231242
UMLS CUI [3,2]
C0205390
UMLS CUI [3,3]
C0717758
Il1-receptor antagonists
Description

All drugs in the context of the SARS-CoV-2 infection and administered at least once during this phase of disease.

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C2917260
JAK inhibitors (Ruxolitinib)
Description

All drugs in the context of the SARS-CoV-2 infection and administered at least once during this phase of disease.

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C3854325
UMLS CUI [2,1]
C0231242
UMLS CUI [2,2]
C0205390
UMLS CUI [2,3]
C2931926
Immunoglobulines
Description

All drugs in the context of the SARS-CoV-2 infection and administered at least once during this phase of disease.

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0021027
Interferone (any)
Description

All drugs in the context of the SARS-CoV-2 infection and administered at least once during this phase of disease.

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0021747
Apheresis therapy
Description

All drugs in the context of the SARS-CoV-2 infection and administered at least once during this phase of disease.

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0005791
Vitamin D
Description

All drugs in the context of the SARS-CoV-2 infection and administered at least once during this phase of disease.

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0042866
UMLS CUI [1,4]
C1527392
Zinc
Description

All drugs in the context of the SARS-CoV-2 infection and administered at least once during this phase of disease.

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0043481
UMLS CUI [1,4]
C1527392
Convalescent plasma
Description

All drugs in the context of the SARS-CoV-2 infection and administered at least once during this phase of disease.

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0032105
UMLS CUI [1,4]
C0740326
Complicated phase: Treatments received, Heart / circulatory medication
Description

Complicated phase: Treatments received, Heart / circulatory medication

Alias
UMLS CUI-1
C0231242
UMLS CUI-2
C0205390
UMLS CUI-3
C0007226
UMLS CUI-4
C0013227
ACE inhibitors (e.g. enalapril, captopril, most drugs ending on -pril)
Description

All drugs in the context of the SARS-CoV-2 infection and administered at least once during this phase of disease.

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0003015
UMLS CUI [2,1]
C0231242
UMLS CUI [2,2]
C0205390
UMLS CUI [2,3]
C0006938
UMLS CUI [3,1]
C0231242
UMLS CUI [3,2]
C0205390
UMLS CUI [3,3]
C0014025
Betablockers (e.g. bisoprolol, metoprolol, most drugs ending on -prolol)
Description

All drugs in the context of the SARS-CoV-2 infection and administered at least once during this phase of disease.

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0053799
UMLS CUI [2,1]
C0231242
UMLS CUI [2,2]
C0205390
UMLS CUI [2,3]
C0025859
UMLS CUI [3,1]
C0231242
UMLS CUI [3,2]
C0205390
UMLS CUI [3,3]
C0304516
AT-II-receptor-1-antagonists (e.g. candesartan, losartan, most drugs ending on -sartan)
Description

All drugs in the context of the SARS-CoV-2 infection and administered at least once during this phase of disease.

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0521942
UMLS CUI [2,1]
C0231242
UMLS CUI [2,2]
C0205390
UMLS CUI [2,3]
C0126174
UMLS CUI [3,1]
C0231242
UMLS CUI [3,2]
C0205390
UMLS CUI [3,3]
C0717550
Other antihypertensives
Description

All drugs in the context of the SARS-CoV-2 infection and administered at least once during this phase of disease.

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0003364
UMLS CUI [1,4]
C0205394
Statines (e.g. atorvastatin, pravastatin, most drugs ending on -statin)
Description

All drugs in the context of the SARS-CoV-2 infection and administered at least once during this phase of disease.

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0286651
UMLS CUI [2,1]
C0231242
UMLS CUI [2,2]
C0205390
UMLS CUI [2,3]
C0085542
UMLS CUI [3,1]
C0231242
UMLS CUI [3,2]
C0205390
UMLS CUI [3,3]
C0360714
Anti-arrhythmics (e.g. digitoxine, verapamil)
Description

All drugs in the context of the SARS-CoV-2 infection and administered at least once during this phase of disease.

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0003195
UMLS CUI [2,1]
C0231242
UMLS CUI [2,2]
C0205390
UMLS CUI [2,3]
C0042523
UMLS CUI [3,1]
C0231242
UMLS CUI [3,2]
C0205390
UMLS CUI [3,3]
C0012258
Adrenaline or other sympathomimetics (e.g. noradrenaline, dobutamine, epinephrine)
Description

All drugs in the context of the SARS-CoV-2 infection and administered at least once during this phase of disease.

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0014563
UMLS CUI [2,1]
C0231242
UMLS CUI [2,2]
C0205390
UMLS CUI [2,3]
C0012963
UMLS CUI [3,1]
C0231242
UMLS CUI [3,2]
C0205390
UMLS CUI [3,3]
C0028351
UMLS CUI [4,1]
C0231242
UMLS CUI [4,2]
C0205390
UMLS CUI [4,3]
C0205394
UMLS CUI [4,4]
C0039052
Vasopressin (e.g. argipressin, arginine vasopressin)
Description

All drugs in the context of the SARS-CoV-2 infection and administered at least once during this phase of disease.

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0042413
UMLS CUI [2,1]
C0231242
UMLS CUI [2,2]
C0205390
UMLS CUI [2,3]
C0003779
Iloprost
Description

All drugs in the context of the SARS-CoV-2 infection and administered at least once during this phase of disease.

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0079594
Nitrates (nitroglycerin, ISMN, Molsidomin, NO)
Description

All drugs in the context of the SARS-CoV-2 infection and administered at least once during this phase of disease.

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C3654024
UMLS CUI [2,1]
C0231242
UMLS CUI [2,2]
C0205390
UMLS CUI [2,3]
C0017887
UMLS CUI [3,1]
C0231242
UMLS CUI [3,2]
C0205390
UMLS CUI [3,3]
C0064079
UMLS CUI [4,1]
C0231242
UMLS CUI [4,2]
C0205390
UMLS CUI [4,3]
C0026400
UMLS CUI [5,1]
C0231242
UMLS CUI [5,2]
C0205390
UMLS CUI [5,3]
C0028215
Aviptadil (VIP analog)
Description

All drugs in the context of the SARS-CoV-2 infection and administered at least once during this phase of disease.

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C1098515
UMLS CUI [2,1]
C0231242
UMLS CUI [2,2]
C0205390
UMLS CUI [2,3]
C0042395
UMLS CUI [2,4]
C0243071
Colchicine
Description

All drugs in the context of the SARS-CoV-2 infection and administered at least once during this phase of disease.

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0009262
Complicated phase: Non-oral anticoagulants
Description

Complicated phase: Non-oral anticoagulants

Alias
UMLS CUI-1
C0231242
UMLS CUI-2
C0205390
UMLS CUI-3
C0003280
UMLS CUI-4
C0332300
UMLS CUI-5
C0442027
Heparin, prophylactic dose
Description

CO (Heparin, prophylactic)

Data type

boolean

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0019134
UMLS CUI [1,4]
C0199176
Heparin, therapeutic dose
Description

CO (Heparin, therapeutic)

Data type

boolean

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0019134
UMLS CUI [1,4]
C0302350
Heparin, subtherapeutic dose (but higher than prophylactic dose)
Description

CO (Heparin intermediate)

Data type

boolean

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0019134
UMLS CUI [1,4]
C0205103
UMLS CUI [1,5]
C0087111
UMLS CUI [1,6]
C0199176
Low molecular weight heparin (enoxaparin, fraxiparin, etc.), prophylactic dose
Description

CO (Low molecular weight heparin, prophylactic (enoxaparin, fraxiparin, etc.))

Data type

boolean

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0019139
UMLS CUI [1,4]
C0199176
UMLS CUI [2,1]
C0231242
UMLS CUI [2,2]
C0205390
UMLS CUI [2,3]
C0206460
UMLS CUI [2,4]
C0199176
UMLS CUI [3,1]
C0231242
UMLS CUI [3,2]
C0205390
UMLS CUI [3,3]
C0878354
UMLS CUI [3,4]
C0199176
Low molecular weight heparin (enoxaparin, fraxiparin, etc.), therapeutic dose
Description

CO (Low molecular weight heparin, therapeutic (enoxaparin, fraxiparin, etc.))

Data type

boolean

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0019139
UMLS CUI [1,4]
C0302350
UMLS CUI [2,1]
C0231242
UMLS CUI [2,2]
C0205390
UMLS CUI [2,3]
C0206460
UMLS CUI [2,4]
C0302350
UMLS CUI [3,1]
C0231242
UMLS CUI [3,2]
C0205390
UMLS CUI [3,3]
C0878354
UMLS CUI [3,4]
C0302350
Low molecular weight heparin (enoxaparin, fraxiparin, etc.), subtherapeutic dose (but higher than prophylactic dose)
Description

CO (Low molecular weight heparin, intermediate (enoxaparin, fraxiparin, etc.))

Data type

boolean

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0019139
UMLS CUI [1,4]
C0205103
UMLS CUI [1,5]
C0087111
UMLS CUI [1,6]
C0199176
UMLS CUI [2,1]
C0231242
UMLS CUI [2,2]
C0205390
UMLS CUI [2,3]
C0206460
UMLS CUI [2,4]
C0205103
UMLS CUI [2,5]
C0087111
UMLS CUI [2,6]
C0199176
UMLS CUI [3,1]
C0231242
UMLS CUI [3,2]
C0205390
UMLS CUI [3,3]
C0878354
UMLS CUI [3,4]
C0205103
UMLS CUI [3,5]
C0087111
UMLS CUI [3,6]
C0199176
Argatroban
Description

CO (Argatroban)

Data type

boolean

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0048470
Complicated phase: Oral anticoagulants
Description

Complicated phase: Oral anticoagulants

Alias
UMLS CUI-1
C0231242
UMLS CUI-2
C0205390
UMLS CUI-3
C0354604
Warfarin / marcumar
Description

CO (Warfarin / marcumar)

Data type

boolean

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0043031
UMLS CUI [2,1]
C0231242
UMLS CUI [2,2]
C0205390
UMLS CUI [2,3]
C0918269
New / direct oral anticoagulants (rivaroxaban, apixaban, dabigatran)
Description

CO (New / direct oral anticoagulants(rivaroxaban, apixaban, dabigatran))

Data type

boolean

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0360593
UMLS CUI [1,4]
C0354604
UMLS CUI [2,1]
C0231242
UMLS CUI [2,2]
C0205390
UMLS CUI [2,3]
C1739768
UMLS CUI [3,1]
C0231242
UMLS CUI [3,2]
C0205390
UMLS CUI [3,3]
C1831808
UMLS CUI [4,1]
C0231242
UMLS CUI [4,2]
C0205390
UMLS CUI [4,3]
C2348066
Complicated phase: Platelet aggregation inhibition
Description

Complicated phase: Platelet aggregation inhibition

Alias
UMLS CUI-1
C0231242
UMLS CUI-2
C0205390
UMLS CUI-3
C0032177
Aspirin
Description

CO (Aspirin)

Data type

boolean

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0004057
ADP receptor inhibitors (Clopidogrel, Cangrelor, Ticagrelor)
Description

CO (ADP receptor inhibitors)

Data type

boolean

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C1373149
UMLS CUI [2,1]
C0231242
UMLS CUI [2,2]
C0205390
UMLS CUI [2,3]
C0070166
UMLS CUI [3,1]
C0231242
UMLS CUI [3,2]
C0205390
UMLS CUI [3,3]
C1121991
UMLS CUI [4,1]
C0231242
UMLS CUI [4,2]
C0205390
UMLS CUI [4,3]
C1999375
Glycoprotein IIB/IIIA inhibitors
Description

CO (Glycoprotein IIB/IIIA inhibitors)

Data type

boolean

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C1373125
Complicated phase: Further anticoagulation / platelet aggregation inhibition
Description

Complicated phase: Further anticoagulation / platelet aggregation inhibition

Alias
UMLS CUI-1
C0231242
UMLS CUI-2
C0205390
UMLS CUI-3
C0205394
UMLS CUI-4
C0003281
UMLS CUI-5
C0032177
Other anticoagulation/platelet aggregation inhibition
Description

CO (Other anticoagulation/platelet aggregation inhibition)

Data type

boolean

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0205394
UMLS CUI [1,4]
C0003281
UMLS CUI [2,1]
C0231242
UMLS CUI [2,2]
C0205390
UMLS CUI [2,3]
C0205394
UMLS CUI [2,4]
C0032177
Indicate other anticoagulation/platelet aggregation inhibition
Description

CO (indicate other anticoagulation/platelet aggregation inhibition)

Data type

text

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0205394
UMLS CUI [1,4]
C0003281
UMLS CUI [1,5]
C1521902
UMLS CUI [2,1]
C0231242
UMLS CUI [2,2]
C0205390
UMLS CUI [2,3]
C0205394
UMLS CUI [2,4]
C0032177
UMLS CUI [2,5]
C1521902
No anticoagulation/platelet aggregation inhibition
Description

CO (No anticoagulation/platelet aggregation inhibition)

Data type

boolean

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0549184
UMLS CUI [1,4]
C0003281
UMLS CUI [2,1]
C0231242
UMLS CUI [2,2]
C0205390
UMLS CUI [2,3]
C0549184
UMLS CUI [2,4]
C0032177
Unknown anticoagulation/platelet aggregation inhibition
Description

CO (Unknown anticoagulation/platelet aggregation inhibition)

Data type

boolean

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0439673
UMLS CUI [1,4]
C0003281
UMLS CUI [2,1]
C0231242
UMLS CUI [2,2]
C0205390
UMLS CUI [2,3]
C0439673
UMLS CUI [2,4]
C0032177
Complicated phase: Other COVID-19 related therapy
Description

Complicated phase: Other COVID-19 related therapy

Alias
UMLS CUI-1
C0231242
UMLS CUI-2
C0205390
UMLS CUI-3
C5203670
UMLS CUI-4
C0087111
UMLS CUI-5
C0205394
Mucolytic agents
Description

CO (Mucolytic agents)

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0026698
Nonsteroidal anti-inflammatory drugs (e.g. aspirin, ibuprofen, naproxen, diclofenac, coxibs)
Description

CO (Nonsteroidal anti-inflammatory drugs, e.g. aspirin, ibuprofen, naproxen, diclofenac, coxibs)

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0003211
UMLS CUI [2,1]
C0231242
UMLS CUI [2,2]
C0205390
UMLS CUI [2,3]
C0004057
UMLS CUI [3,1]
C0231242
UMLS CUI [3,2]
C0205390
UMLS CUI [3,3]
C0020740
UMLS CUI [4,1]
C0231242
UMLS CUI [4,2]
C0205390
UMLS CUI [4,3]
C0027396
UMLS CUI [5,1]
C0231242
UMLS CUI [5,2]
C0205390
UMLS CUI [5,3]
C0012091
UMLS CUI [6,1]
C0231242
UMLS CUI [6,2]
C0205390
UMLS CUI [6,3]
C1257954
Paracetamol
Description

CO (Paracetamol)

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0000970
Metamizole
Description

CO (Metamizole)

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C3714569
Other COVID-19 related drug therapy
Description

CO (Other COVID-19 related drug therapy)

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C5203670
UMLS CUI [1,4]
C0087111
UMLS CUI [1,5]
C0205394
Indicate other COVID-19 related drug therapy
Description

CO (Other COVID-19 related drug therapy_text)

Data type

text

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C5203670
UMLS CUI [1,4]
C0087111
UMLS CUI [1,5]
C0205394
UMLS CUI [1,6]
C1521902
Complicated phase: Co/Superinfections
Description

Complicated phase: Co/Superinfections

Alias
UMLS CUI-1
C0231242
UMLS CUI-2
C0205390
UMLS CUI-3
C0275524
UMLS CUI-4
C0038826
Proven bacterial infection
Description

CO (Proven bacterial infection)

Data type

boolean

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0004623
UMLS CUI [1,4]
C0456369
Indicate site and respective pathogen of proven bacterial infection
Description

Please fill in the site and respective pathogen if available. Please note if it is a co-infection (co-infection).

Data type

text

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0004623
UMLS CUI [1,4]
C0456369
UMLS CUI [1,5]
C1521902
Probable or suspected bacterial infection
Description

CO (probable or suspected bacterial infection)

Data type

boolean

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0004623
UMLS CUI [1,4]
C0332147
UMLS CUI [2,1]
C0231242
UMLS CUI [2,2]
C0205390
UMLS CUI [2,3]
C0004623
UMLS CUI [2,4]
C0332148
Indicate site and respective pathogen of probable or suspected bacterial infection
Description

Please fill in the site and respective pathogen if available. Please note if it is a co-infection (co-infection).

Data type

text

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0004623
UMLS CUI [1,4]
C0332147
UMLS CUI [1,5]
C1521902
UMLS CUI [2,1]
C0231242
UMLS CUI [2,2]
C0205390
UMLS CUI [2,3]
C0004623
UMLS CUI [2,4]
C0332148
UMLS CUI [2,5]
C1521902
Proven fungal infection
Description

CO (Proven fungal infection)

Data type

boolean

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0026946
UMLS CUI [1,4]
C0456369
Indicate site and respective pathogen of proven fungal infection
Description

Please fill in the site and respective pathogen if available. Please note if it is a co-infection (co-infection).

Data type

text

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0026946
UMLS CUI [1,4]
C0456369
UMLS CUI [1,5]
C1521902
Probable or suspected fungal infection
Description

CO (probable or suspected fungal infection)

Data type

boolean

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0026946
UMLS CUI [1,4]
C0332147
UMLS CUI [2,1]
C0231242
UMLS CUI [2,2]
C0205390
UMLS CUI [2,3]
C0026946
UMLS CUI [2,4]
C0332148
Indicate site and respective pathogen of probable or suspected fungal infection
Description

Please fill in the site and respective pathogen if available. Please note if it is a co-infection (co-infection).

Data type

text

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0026946
UMLS CUI [1,4]
C0332147
UMLS CUI [1,5]
C1521902
UMLS CUI [2,1]
C0231242
UMLS CUI [2,2]
C0205390
UMLS CUI [2,3]
C0026946
UMLS CUI [2,4]
C0332148
UMLS CUI [2,5]
C1521902
None
Description

CO (No Co/Superinfection)

Data type

boolean

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0549184
UMLS CUI [1,4]
C0038826
UMLS CUI [2,1]
C0231242
UMLS CUI [2,2]
C0205390
UMLS CUI [2,3]
C0549184
UMLS CUI [2,4]
C0275524
Unknown
Description

CO (Unknown Co/superinfection)

Data type

boolean

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0439673
UMLS CUI [1,4]
C0038826
UMLS CUI [2,1]
C0231242
UMLS CUI [2,2]
C0205390
UMLS CUI [2,3]
C0439673
UMLS CUI [2,4]
C0275524
Complicated phase: Antibacterial treatment: Betalactams
Description

Complicated phase: Antibacterial treatment: Betalactams

Alias
UMLS CUI-1
C0231242
UMLS CUI-2
C0205390
UMLS CUI-3
C0279516
UMLS CUI-4
C0087111
UMLS CUI-5
C0282215
Penicillins/ aminopenicilins
Description

Please indicate all antibacterials administered at least once for antibacterial treatment during this phase. Please note that antibacterial prophylaxis should not be mentioned here.

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0030842
UMLS CUI [2,1]
C0231242
UMLS CUI [2,2]
C0205390
UMLS CUI [2,3]
C0304324
Cephalosporins I-III
Description

Please indicate all antibacterials administered at least once for antibacterial treatment during this phase. Please note that antibacterial prophylaxis should not be mentioned here.

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0304317
UMLS CUI [2,1]
C0231242
UMLS CUI [2,2]
C0205390
UMLS CUI [2,3]
C0304319
UMLS CUI [3,1]
C0231242
UMLS CUI [3,2]
C0205390
UMLS CUI [3,3]
C0304320
Carbapenems (meropenem, imipenem, ertapenem, doripenem)
Description

Please indicate all antibacterials administered at least once for antibacterial treatment during this phase. Please note that antibacterial prophylaxis should not be mentioned here.

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0006968
UMLS CUI [2,1]
C0231242
UMLS CUI [2,2]
C0205390
UMLS CUI [2,3]
C0066005
UMLS CUI [3,1]
C0231242
UMLS CUI [3,2]
C0205390
UMLS CUI [3,3]
C0020933
UMLS CUI [4,1]
C0231242
UMLS CUI [4,2]
C0205390
UMLS CUI [4,3]
C1120106
UMLS CUI [5,1]
C0231242
UMLS CUI [5,2]
C0205390
UMLS CUI [5,3]
C0389169
Piperacillin/tazobactam
Description

Please indicate all antibacterials administered at least once for antibacterial treatment during this phase. Please note that antibacterial prophylaxis should not be mentioned here.

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0250480
New betalactams for multi-resistent bacteria (ceftazidime/avibactam, ceftolozane/tazobactam, cefiderocol)
Description

Please indicate all antibacterials administered at least once for antibacterial treatment during this phase. Please note that antibacterial prophylaxis should not be mentioned here.

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0205314
UMLS CUI [1,4]
C0282215
UMLS CUI [1,5]
C3826980
UMLS CUI [2,1]
C0231242
UMLS CUI [2,2]
C0205390
UMLS CUI [2,3]
C3656596
UMLS CUI [3,1]
C0231242
UMLS CUI [3,2]
C0205390
UMLS CUI [3,3]
C3656593
UMLS CUI [4,1]
C0231242
UMLS CUI [4,2]
C0205390
UMLS CUI [4,3]
C4548369
Complicated phase: Antibacterial treatment: Macrolides
Description

Complicated phase: Antibacterial treatment: Macrolides

Alias
UMLS CUI-1
C0231242
UMLS CUI-2
C0205390
UMLS CUI-3
C0279516
UMLS CUI-4
C0087111
UMLS CUI-5
C0003240
Azithromycin
Description

Please indicate all antibacterials administered at least once for antibacterial treatment during this phase. Please note that antibacterial prophylaxis should not be mentioned here.

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0052796
Other macrolide (erythromycin, clarithromycin, roxithromycin)
Description

Please indicate all antibacterials administered at least once for antibacterial treatment during this phase. Please note that antibacterial prophylaxis should not be mentioned here.

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0003240
UMLS CUI [1,4]
C0205394
UMLS CUI [2,1]
C0231242
UMLS CUI [2,2]
C0205390
UMLS CUI [2,3]
C0014806
UMLS CUI [3,1]
C0231242
UMLS CUI [3,2]
C0205390
UMLS CUI [3,3]
C0055856
UMLS CUI [4,1]
C0231242
UMLS CUI [4,2]
C0205390
UMLS CUI [4,3]
C0035891
Complicated phase: Antibacterial treatment: Other antibacterial treatment
Description

Complicated phase: Antibacterial treatment: Other antibacterial treatment

Alias
UMLS CUI-1
C0231242
UMLS CUI-2
C0205390
UMLS CUI-3
C0279516
UMLS CUI-4
C0087111
UMLS CUI-5
C0205394
Glycopeptides (vancomycin, teicoplanin)
Description

Please indicate all antibacterials administered at least once for antibacterial treatment during this phase. Please note that antibacterial prophylaxis should not be mentioned here.

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0017953
UMLS CUI [2,1]
C0231242
UMLS CUI [2,2]
C0205390
UMLS CUI [2,3]
C0042313
UMLS CUI [3,1]
C0231242
UMLS CUI [3,2]
C0205390
UMLS CUI [3,3]
C0145106
Other gram-positive active drugs for multiresistant bacteria (e.g. linezolid, daptomycin)
Description

Please indicate all antibacterials administered at least once for antibacterial treatment during this phase. Please note that antibacterial prophylaxis should not be mentioned here.

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0205394
UMLS CUI [1,4]
C0018154
UMLS CUI [1,5]
C3826980
UMLS CUI [2,1]
C0231242
UMLS CUI [2,2]
C0205390
UMLS CUI [2,3]
C0663241
UMLS CUI [3,1]
C0231242
UMLS CUI [3,2]
C0205390
UMLS CUI [3,3]
C0057144
Fluorochinolones (ciprofloxacin, moxifloxacin, levofloxacin)
Description

Please indicate all antibacterials administered at least once for antibacterial treatment during this phase. Please note that antibacterial prophylaxis should not be mentioned here.

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0034428
UMLS CUI [2,1]
C0231242
UMLS CUI [2,2]
C0205390
UMLS CUI [2,3]
C0008809
UMLS CUI [3,1]
C0231242
UMLS CUI [3,2]
C0205390
UMLS CUI [3,3]
C0536495
UMLS CUI [4,1]
C0231242
UMLS CUI [4,2]
C0205390
UMLS CUI [4,3]
C0282386
Other antibacterial treatment
Description

Please indicate all antibacterials administered at least once for antibacterial treatment during this phase. Please note that antibacterial prophylaxis should not be mentioned here.

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0279516
UMLS CUI [1,4]
C0205394
Indicate other antibacterial treatment
Description

Please indicate all antibacterials administered at least once for antibacterial treatment during this phase. Please note that antibacterial prophylaxis should not be mentioned here.

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0279516
UMLS CUI [1,4]
C0205394
UMLS CUI [1,5]
C1521902
Complicated phase: Complications, Thrombotic and thromboembolic manifestations
Description

Complicated phase: Complications, Thrombotic and thromboembolic manifestations

Alias
UMLS CUI-1
C0231242
UMLS CUI-2
C0205390
UMLS CUI-3
C0009566
UMLS CUI-4
C0040053
UMLS CUI-5
C0040038
Abdominal thrombosis/thromboembolism (venous or arterial)
Description

CO (venous or arterial abdominal thrombosis/thromboembolism)

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0151942
UMLS CUI [1,4]
C0000726
UMLS CUI [2,1]
C0231242
UMLS CUI [2,2]
C0205390
UMLS CUI [2,3]
C0042487
UMLS CUI [2,4]
C0000726
UMLS CUI [3,1]
C0231242
UMLS CUI [3,2]
C0205390
UMLS CUI [3,3]
C3544094
UMLS CUI [3,4]
C0000726
UMLS CUI [4,1]
C0231242
UMLS CUI [4,2]
C0205390
UMLS CUI [4,3]
C1861172
UMLS CUI [4,4]
C0000726
Myocardial infarction
Description

CO (Myocardial infarction)

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0027051
Venous thromboses, e.g. leg vein thrombosis
Description

CO (Venous thromboses, e.g. leg vein thrombosis)

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0042487
UMLS CUI [2,1]
C0231242
UMLS CUI [2,2]
C0205390
UMLS CUI [2,3]
C0149871
Pulmonary embolism
Description

CO (Pulmonary embolism)

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0034065
Microangiopathies and microthromboses
Description

CO (Microangiopathies and microthromboses)

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C2717961
UMLS CUI [2,1]
C0231242
UMLS CUI [2,2]
C0205390
UMLS CUI [2,3]
C3686869
Complicated phase: Complications, Neurological
Description

Complicated phase: Complications, Neurological

Alias
UMLS CUI-1
C0231242
UMLS CUI-2
C0205390
UMLS CUI-3
C0009566
UMLS CUI-4
C0027763
Intracerebral bleeding
Description

CO (Intracerebral bleeding)

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C2937358
Ischemic Stroke
Description

CO (Ischemic Stroke)

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0948008
Meningitis / Encephalitis
Description

CO (Meningitis / Encephalitis)

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0497299
Critical Illness Myopathy (CIM)
Description

CO (Critical Illness Myopathy)

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0010340
UMLS CUI [1,4]
C0026848
Critical Illness Polyneuropathy (CIP)
Description

CO (Critical Illness Polyneuropathy)

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0010340
UMLS CUI [1,4]
C0152025
Seizure
Description

CO (Seizure)

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0036572
Ischemic stroke: TOAST classification
Description

Ischemic stroke: TOAST classification

Alias
UMLS CUI-1
C0231242
UMLS CUI-2
C0205390
UMLS CUI-3
C0948008
UMLS CUI-4
C1710306
State most likely cause of ischemic stroke (TOAST)
Description

CO (Cause of ischemic stroke (TOAST))

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0948008
UMLS CUI [1,4]
C1710306
UMLS CUI [1,5]
C0085978
Ischemic stroke: NIHSS score in acute phase
Description

Ischemic stroke: NIHSS score in acute phase

Alias
UMLS CUI-1
C0231242
UMLS CUI-2
C0205390
UMLS CUI-3
C0948008
UMLS CUI-4
C4269147
UMLS CUI-5
C0439557
Indicate NIHSS score in acute phase
Description

The maximum possible score is 42, the minimum score 0.

Data type

text

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0948008
UMLS CUI [1,4]
C4269147
UMLS CUI [1,5]
C0439557
Complicated phase: Complications, Other
Description

Complicated phase: Complications, Other

Alias
UMLS CUI-1
C0231242
UMLS CUI-2
C0205390
UMLS CUI-3
C0009566
UMLS CUI-4
C0205394
Myocarditis
Description

CO (Myocarditis)

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0027059
Vasculitis
Description

CO (Vasculitis)

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0042384
Gastrointestinal bleeding
Description

CO (Gastrointestinal bleeding)

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0017181
Other complication
Description

CO (Other complication)

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0205394
UMLS CUI [1,4]
C0009566
Indicate other complication
Description

CO (indicate other complication)

Data type

text

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0205394
UMLS CUI [1,4]
C0009566
UMLS CUI [1,5]
C1521902
Acute kidney injury (KDIGO criteria)
Description

Acute kidney injury (KDIGO criteria)

Alias
UMLS CUI-1
C0231242
UMLS CUI-2
C0205390
UMLS CUI-3
C2609414
UMLS CUI-4
C0679228
Acute kidney injury (KDIGO criteria)
Description

Definition of stages according to KDIGO: Stage 1: one of the following: Serum creatinine increased 1.5-1.9 times baseline; Serum creatinine increase >0.3mg/dl (26.5 umol/l; Urinary output <0.5ml/kg/h during a 6 hour block Stage 2: one of the following: Serum creatinine increase 2.0-2.9 times baseline; Urinary output <0.3ml/kg/h during two 6 hour blocks Stage 3: one of the following: Serum creatinine increase >3 times baseline; Serum creatinine increases to >4.0mg/dl )353 umol/l); Initiation of renal replacement therapy; Urinary output <0.3ml/kg/h during more than 24 hours; Anuria for more than 12 hours

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C2609414
UMLS CUI [1,4]
C0679228
Complicated phase: SOFA score
Description

Complicated phase: SOFA score

Alias
UMLS CUI-1
C0231242
UMLS CUI-2
C0205390
UMLS CUI-3
C3494459
Complicated phase: SOFA score
Description

Worst during this phase of disease. Enter 999, if unavailable.

Data type

integer

Alias
UMLS CUI [1,1]
C3494459
UMLS CUI [1,2]
C1522166
UMLS CUI [1,3]
C0231242
UMLS CUI [1,4]
C0205390
Complicated phase: Is data entry for this section finished?
Description

Complicated phase: Is data entry for this section finished?

Alias
UMLS CUI-1
C4684556
UMLS CUI-2
C1828479
UMLS CUI-3
C0205197
Complicated phase: Is data entry for this section finished?
Description

CO_Completed

Data type

integer

Alias
UMLS CUI [1,1]
C4684556
UMLS CUI [1,2]
C1828479
UMLS CUI [1,3]
C0205197

Similar models

Complicated Phase

Name
Type
Description | Question | Decode (Coded Value)
Data type
Alias
Item Group
Symptoms / findings of complicated phase:
C0243095 (UMLS CUI-1)
C1457887 (UMLS CUI-2)
C0231242 (UMLS CUI-3)
C0205390 (UMLS CUI-4)
CO (paO2 at room air)
Item
paO2 at room air < 70 mmHg
boolean
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0202155 (UMLS CUI [1,3])
C2709070 (UMLS CUI [1,4])
CO (SO2 at room air)
Item
SO2 at room air < 90 mmHg
boolean
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0523807 (UMLS CUI [1,3])
C2709070 (UMLS CUI [1,4])
CO (AST | ALT)
Item
AST or ALT > 5x ULN
boolean
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0201899 (UMLS CUI [1,3])
C0231242 (UMLS CUI [2,1])
C0205390 (UMLS CUI [2,2])
C0201836 (UMLS CUI [2,3])
CO (New cardiac arrhythmia)
Item
New cardiac arrhythmia
boolean
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0003811 (UMLS CUI [1,3])
C0205314 (UMLS CUI [1,4])
CO (New pericardial effusion)
Item
New pericardial effusion >1cm
boolean
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0031039 (UMLS CUI [1,3])
C0205314 (UMLS CUI [1,4])
CO (New heart failure with pulmonary edema, congestive hepatopathy or peripheral edema)
Item
New heart failure with pulmonary edema, congestive hepatopathy or peripheral edema
boolean
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0205314 (UMLS CUI [1,3])
C0018801 (UMLS CUI [1,4])
C0034063 (UMLS CUI [1,5])
C0231242 (UMLS CUI [2,1])
C0205390 (UMLS CUI [2,2])
C0205314 (UMLS CUI [2,3])
C0018801 (UMLS CUI [2,4])
C0085649 (UMLS CUI [2,5])
C0231242 (UMLS CUI [3,1])
C0205390 (UMLS CUI [3,2])
C0205314 (UMLS CUI [3,3])
C0018801 (UMLS CUI [3,4])
C0023895 (UMLS CUI [3,5])
CO (Need for oxygen supplementation, based on clinical impression or test result)
Item
Need for oxygen supplementation (based on clinical impression or test results)
boolean
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0686904 (UMLS CUI [1,3])
C0919655 (UMLS CUI [1,4])
C2973287 (UMLS CUI [1,5])
C0231242 (UMLS CUI [2,1])
C0205390 (UMLS CUI [2,2])
C0686904 (UMLS CUI [2,3])
C0919655 (UMLS CUI [2,4])
C0456984 (UMLS CUI [2,5])
CO (Increase of prior oxygen home therapy)
Item
Clinically meaningful increase of prior oxygen home therapy
boolean
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0421203 (UMLS CUI [1,3])
C1514463 (UMLS CUI [1,4])
C0442805 (UMLS CUI [1,5])
Item Group
Complicated phase: Feeling of breathlessness
C0231242 (UMLS CUI-1)
C0205390 (UMLS CUI-2)
C0013404 (UMLS CUI-3)
Item
Feeling of breathlessness
integer
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0013404 (UMLS CUI [1,3])
Code List
Feeling of breathlessness
CL Item
Mild (1)
CL Item
Moderate (2)
CL Item
Severe (3)
CL Item
None (4)
CL Item
Unknown (5)
Item Group
Complicated phase: Fever
C0231242 (UMLS CUI-1)
C0205390 (UMLS CUI-2)
C0015967 (UMLS CUI-3)
Item
Complicated phase: Duration of fever
integer
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0015967 (UMLS CUI [1,3])
C0449238 (UMLS CUI [1,4])
Code List
Complicated phase: Duration of fever
CL Item
1-3 days (1)
CL Item
4-7 days (2)
CL Item
8-14 days (3)
CL Item
15-30 days (4)
CL Item
> 30 days (5)
CL Item
Unknown (6)
Item Group
Complicated phase: Vital signs
C0231242 (UMLS CUI-1)
C0205390 (UMLS CUI-2)
C0518766 (UMLS CUI-3)
Item
Systolic BP in CO
integer
C0871470 (UMLS CUI [1,1])
C1522166 (UMLS CUI [1,2])
C0231242 (UMLS CUI [1,3])
C0205390 (UMLS CUI [1,4])
CL Item
< 80 mmHg (1)
CL Item
80 - 99 mmHg (2)
CL Item
100 - 119 mmHg (3)
CL Item
120 - 139 mmHg (4)
CL Item
140 - 159 mmHg (5)
CL Item
160 - 179 mmHg (6)
CL Item
> 179 mmHg (7)
CL Item
Not done (8)
CL Item
Unknown (9)
Item
Diastolic BP in CO
integer
C0428883 (UMLS CUI [1,1])
C1522166 (UMLS CUI [1,2])
C0231242 (UMLS CUI [1,3])
C0205390 (UMLS CUI [1,4])
CL Item
< 40 mmHg (1)
CL Item
40 - 59 mmHg (2)
CL Item
60 - 89 mmHg (3)
CL Item
90 - 109 mmHg (4)
CL Item
110 - 119 mmHg (5)
CL Item
> 119 mmHg (6)
CL Item
Unknown (7)
CL Item
Unknown (7)
Item
Pulse in CO
integer
C0232117 (UMLS CUI [1,1])
C1522166 (UMLS CUI [1,2])
C0231242 (UMLS CUI [1,3])
C0205390 (UMLS CUI [1,4])
CL Item
< 45 bpm (1)
CL Item
45 - 59 bpm (2)
CL Item
60 - 89 bpm (3)
CL Item
90 - 119 bpm (4)
CL Item
> 119 bpm (5)
CL Item
Not done (6)
CL Item
Unknown (7)
Item
SO2 in CO
integer
C0523807 (UMLS CUI [1,1])
C1522166 (UMLS CUI [1,2])
C0231242 (UMLS CUI [1,3])
C0205390 (UMLS CUI [1,4])
CL Item
< 60% (1)
CL Item
60 - 69% (2)
CL Item
70 - 79% (3)
CL Item
80 - 89% (4)
CL Item
90 - 95% (5)
CL Item
96 - 100% (6)
CL Item
Not done (7)
CL Item
Unknown (8)
Item
paO2 in CO
integer
C0202155 (UMLS CUI [1,1])
C1522166 (UMLS CUI [1,2])
C0231242 (UMLS CUI [1,3])
C0205390 (UMLS CUI [1,4])
CL Item
< 50 mmHg (< 6.66 kPa) (1)
CL Item
50 - 59 mmHg (6.67 - 7.86 kPa) (2)
CL Item
60 - 69 mmHg (7.87 - 9.2 kPa) (3)
CL Item
70 - 79 mmHg (9.21 - 10.53 kPa) (4)
CL Item
> 79 mmHg (> 10.53 kPa) (5)
CL Item
Not done (6)
CL Item
Unknown (7)
Item
paCO2 in CO
integer
C1822070 (UMLS CUI [1,1])
C1522166 (UMLS CUI [1,2])
C0231242 (UMLS CUI [1,3])
C0205390 (UMLS CUI [1,4])
CL Item
< 30 mmHg (< 4 kPa) (1)
CL Item
30 - 38 mmHg (4 - 5.06 kPa) (2)
CL Item
39 - 45 mmHg (5.07 - 5.99 kPa) (3)
CL Item
46 - 55 mmHg (6 - 7.33 kPa) (4)
CL Item
> 55 mmHg (> 7.33 kPa) (5)
CL Item
Not done (6)
CL Item
Unknown (7)
Item
Temperature in CO
integer
C0039476 (UMLS CUI [1,1])
C1522166 (UMLS CUI [1,2])
C0231242 (UMLS CUI [1,3])
C0205390 (UMLS CUI [1,4])
CL Item
< 35.1°C (< 95.2°F) (1)
CL Item
35.1 - 37.2°C (95.2 - 99.0°F) (2)
CL Item
37.3 - 37.9°C (99.1 - 100.2°F) (3)
CL Item
38 - 38.9°C (100.4 - 102.0°F) (4)
CL Item
39 - 39.9°C (102.1 - 103.8°F) (5)
CL Item
> 39.9°C (>103.8 °F) (6)
CL Item
Not done (7)
CL Item
Unknown (8)
Item
Respiratory rate / minute in CO
integer
C0231832 (UMLS CUI [1,1])
C1522166 (UMLS CUI [1,2])
C0231242 (UMLS CUI [1,3])
C0205390 (UMLS CUI [1,4])
CL Item
< 16 (1)
CL Item
16-21 (2)
CL Item
22-29 (3)
CL Item
> 29 (4)
CL Item
Not done (5)
CL Item
Unknown (6)
Item
Glasgow Coma scale (GCS) in CO
integer
C0017594 (UMLS CUI [1,1])
C1522166 (UMLS CUI [1,2])
C0231242 (UMLS CUI [1,3])
C0205390 (UMLS CUI [1,4])
Code List
Glasgow Coma scale (GCS) in CO
CL Item
15 (1)
CL Item
13 - 14 (2)
CL Item
9 - 12 (3)
CL Item
3 - 8 (4)
CL Item
Not done (5)
CL Item
Unknown (6)
Item Group
Complicated phase: Lung ultrasound
C0231242 (UMLS CUI-1)
C0205390 (UMLS CUI-2)
C0203463 (UMLS CUI-3)
CO (worst lung ultrasound, B lines)
Item
B lines (multifocal, discrete or confluent)
boolean
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0203463 (UMLS CUI [1,3])
C1522166 (UMLS CUI [1,4])
C3846158 (UMLS CUI [1,5])
CO (worst lung ultrasound, Confluent B lines)
Item
Confluent B lines
boolean
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0203463 (UMLS CUI [1,3])
C1522166 (UMLS CUI [1,4])
C3846158 (UMLS CUI [1,5])
C0205200 (UMLS CUI [1,6])
CO (worst lung ultrasound, Consolidation)
Item
Consolidation (non translobar and translobar)
boolean
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0203463 (UMLS CUI [1,3])
C1522166 (UMLS CUI [1,4])
C0521530 (UMLS CUI [1,5])
CO (worst lung ultrasound, Multilobar distribution of abnormalities)
Item
Multilobar distribution of abnormalities
boolean
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0203463 (UMLS CUI [1,3])
C1522166 (UMLS CUI [1,4])
C0439064 (UMLS CUI [1,5])
C1522010 (UMLS CUI [1,6])
C1704711 (UMLS CUI [1,7])
C1704258 (UMLS CUI [1,8])
CO (worst lung ultrasound, Small lesions)
Item
Small (centomeric) lesions
boolean
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0203463 (UMLS CUI [1,3])
C1522166 (UMLS CUI [1,4])
C0700321 (UMLS CUI [1,5])
C0221198 (UMLS CUI [1,6])
CO (worst, lung ultrasound, Thickened pleural line)
Item
Thickened pleural line
boolean
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0203463 (UMLS CUI [1,3])
C1522166 (UMLS CUI [1,4])
C0264545 (UMLS CUI [1,5])
CO (Other lung ultrasound result)
Item
Other lung ultrasound results
boolean
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0203463 (UMLS CUI [1,3])
C0205394 (UMLS CUI [1,4])
C1274040 (UMLS CUI [1,5])
CO (indicate other lung ultrasound results)
Item
Indicate other lung ultrasound results
text
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0203463 (UMLS CUI [1,3])
C0205394 (UMLS CUI [1,4])
C1274040 (UMLS CUI [1,5])
C1521902 (UMLS CUI [1,6])
CO (lung ultrasound, no abnormal findings)
Item
No abnormal findings
boolean
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0203463 (UMLS CUI [1,3])
C1704258 (UMLS CUI [1,4])
C0549184 (UMLS CUI [1,5])
CO (lung ultrasound, not done)
Item
Not done
boolean
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0203463 (UMLS CUI [1,3])
C1272696 (UMLS CUI [1,4])
CO (lung ultrasound, unknown)
Item
Unknown
boolean
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0203463 (UMLS CUI [1,3])
C0439673 (UMLS CUI [1,4])
Item Group
Complicated phase: Chest CT results
C0231242 (UMLS CUI-1)
C0205390 (UMLS CUI-2)
C0202823 (UMLS CUI-3)
C1522166 (UMLS CUI-4)
C1274040 (UMLS CUI-5)
CO (worst chest CT, air trapping)
Item
Air trapping
boolean
C0231819 (UMLS CUI [1,1])
C0202823 (UMLS CUI [1,2])
C1522166 (UMLS CUI [1,3])
C0231242 (UMLS CUI [1,4])
C0205390 (UMLS CUI [1,5])
CO (worst chest CT, Areas of consolidation)
Item
Areas of consolidation
boolean
C0521530 (UMLS CUI [1,1])
C0202823 (UMLS CUI [1,2])
C1522166 (UMLS CUI [1,3])
C0231242 (UMLS CUI [1,4])
C0205390 (UMLS CUI [1,5])
CO (worst chest CT, Bronchiolitis)
Item
Bronchiolitis
boolean
C0006271 (UMLS CUI [1,1])
C0202823 (UMLS CUI [1,2])
C1522166 (UMLS CUI [1,3])
C0231242 (UMLS CUI [1,4])
C0205390 (UMLS CUI [1,5])
CO (worst chest CT, Crazy paving pattern)
Item
Crazy paving pattern
boolean
C4476749 (UMLS CUI [1,1])
C1522166 (UMLS CUI [1,2])
C0231242 (UMLS CUI [1,3])
C0205390 (UMLS CUI [1,4])
CO (worst chest CT, Ground glass opacities)
Item
Ground glass opacities
boolean
C3827002 (UMLS CUI [1,1])
C0202823 (UMLS CUI [1,2])
C1522166 (UMLS CUI [1,3])
C0231242 (UMLS CUI [1,4])
C0205390 (UMLS CUI [1,5])
CO (worst chest CT, Interlobular septal thickening)
Item
Interlobular septal thickening
boolean
C4280727 (UMLS CUI [1,1])
C1522166 (UMLS CUI [1,2])
C0231242 (UMLS CUI [1,3])
C0205390 (UMLS CUI [1,4])
CO (worst chest CT, Nodulary lesions)
Item
Nodulary lesions
boolean
C1518345 (UMLS CUI [1,1])
C0202823 (UMLS CUI [1,2])
C1522166 (UMLS CUI [1,3])
C0231242 (UMLS CUI [1,4])
C0205390 (UMLS CUI [1,5])
CO (worst chest CT, Pleural effusion)
Item
Pleural effusion
boolean
C0032227 (UMLS CUI [1,1])
C0202823 (UMLS CUI [1,2])
C1522166 (UMLS CUI [1,3])
C0231242 (UMLS CUI [1,4])
C0205390 (UMLS CUI [1,5])
CO (Chest x-ray)
Item
Chest x-ray results
boolean
C0039985 (UMLS CUI [1,1])
C0231242 (UMLS CUI [1,2])
C0205390 (UMLS CUI [1,3])
CO (indicate chest x-ray result)
Item
Indicate chest x-ray results
text
C0039985 (UMLS CUI [1,1])
C1274040 (UMLS CUI [1,2])
C0231242 (UMLS CUI [1,3])
C0205390 (UMLS CUI [1,4])
CO (Other relevant CT results)
Item
Other relevant chest CT results
boolean
C0205394 (UMLS CUI [1,1])
C1274040 (UMLS CUI [1,2])
C2347946 (UMLS CUI [1,3])
C0202823 (UMLS CUI [1,4])
C0231242 (UMLS CUI [1,5])
C0205390 (UMLS CUI [1,6])
CO (indicate other relevant CT results)
Item
Indicate other relevant chest CT results
text
C0205394 (UMLS CUI [1,1])
C1274040 (UMLS CUI [1,2])
C2347946 (UMLS CUI [1,3])
C1521902 (UMLS CUI [1,4])
C0202823 (UMLS CUI [1,5])
C0231242 (UMLS CUI [1,6])
C0205390 (UMLS CUI [1,7])
CO (Normal CT)
Item
Normal CT
boolean
C0205307 (UMLS CUI [1,1])
C0202823 (UMLS CUI [1,2])
C0231242 (UMLS CUI [1,3])
C0205390 (UMLS CUI [1,4])
CO (chest CT not done)
Item
Not done
boolean
C1272696 (UMLS CUI [1,1])
C0202823 (UMLS CUI [1,2])
C0231242 (UMLS CUI [1,3])
C0205390 (UMLS CUI [1,4])
Item Group
Complicated phase: Treatments received, Antivirals
C0231242 (UMLS CUI-1)
C0205390 (UMLS CUI-2)
C0280274 (UMLS CUI-3)
Item
Atazanavir
integer
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C1145759 (UMLS CUI [1,3])
Code List
Atazanavir
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Darunavir
integer
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C1435444 (UMLS CUI [1,3])
Code List
Darunavir
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Chloroquine phosphate
integer
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0280274 (UMLS CUI [1,3])
C0055447 (UMLS CUI [1,4])
Code List
Chloroquine phosphate
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Hydroxychloroquine
integer
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0280274 (UMLS CUI [1,3])
C0020336 (UMLS CUI [1,4])
Code List
Hydroxychloroquine
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Ivermectin
integer
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0280274 (UMLS CUI [1,3])
C0022322 (UMLS CUI [1,4])
Code List
Ivermectin
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Lopinavir/ritonavir
integer
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0674432 (UMLS CUI [1,3])
C0231242 (UMLS CUI [2,1])
C0205390 (UMLS CUI [2,2])
C0292818 (UMLS CUI [2,3])
Code List
Lopinavir/ritonavir
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Maraviroc
integer
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C1667052 (UMLS CUI [1,3])
Code List
Maraviroc
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Ganciclovir
integer
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0017066 (UMLS CUI [1,3])
Code List
Ganciclovir
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Oseltamivir
integer
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0874161 (UMLS CUI [1,3])
Code List
Oseltamivir
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Remdesivir
integer
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C4726677 (UMLS CUI [1,3])
Code List
Remdesivir
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Ribavirin
integer
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0035525 (UMLS CUI [1,3])
Code List
Ribavirin
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Camostat
integer
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0280274 (UMLS CUI [1,3])
C0129975 (UMLS CUI [1,4])
Code List
Camostat
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Favipiravir
integer
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C1138226 (UMLS CUI [1,3])
Code List
Favipiravir
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
CO (Monoclonal antibody therapy, e.g. Bamlanivimab, REGN-COV-2)
Item
Monoclonal antibody therapy (e.g. Bamlanivimab, REGN-COV-2)
boolean
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0279694 (UMLS CUI [1,3])
C0280274 (UMLS CUI [1,4])
C5421805 (UMLS CUI [2])
C5389881 (UMLS CUI [3])
Item Group
Complicated phase: Treatments received, Antibiotics
C0003232 (UMLS CUI-1)
C0231242 (UMLS CUI-2)
C0205390 (UMLS CUI-3)
Item
Betalactams (penicillins, cephalosporines, carbapenems)
integer
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0282215 (UMLS CUI [1,3])
C0231242 (UMLS CUI [2,1])
C0205390 (UMLS CUI [2,2])
C0006968 (UMLS CUI [2,3])
C0231242 (UMLS CUI [3,1])
C0205390 (UMLS CUI [3,2])
C0030842 (UMLS CUI [3,3])
C0231242 (UMLS CUI [4,1])
C0205390 (UMLS CUI [4,2])
C3536856 (UMLS CUI [4,3])
Code List
Betalactams (penicillins, cephalosporines, carbapenems)
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Azithromycin
integer
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0052796 (UMLS CUI [1,3])
Code List
Azithromycin
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Other macrolide (erythromycin, clarithromycin, roxithromycin)
integer
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0282563 (UMLS CUI [1,3])
C0205394 (UMLS CUI [1,4])
C0231242 (UMLS CUI [2,1])
C0205390 (UMLS CUI [2,2])
C0035891 (UMLS CUI [2,3])
C0231242 (UMLS CUI [3,1])
C0205390 (UMLS CUI [3,2])
C0014806 (UMLS CUI [3,3])
C0231242 (UMLS CUI [4,1])
C0205390 (UMLS CUI [4,2])
C0055856 (UMLS CUI [4,3])
Code List
Other macrolide (erythromycin, clarithromycin, roxithromycin)
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Fluorochinolones (ciprofloxacin, moxifloxacin, levofloxacin)
integer
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0949665 (UMLS CUI [1,3])
C0231242 (UMLS CUI [2,1])
C0205390 (UMLS CUI [2,2])
C0282386 (UMLS CUI [2,3])
C0231242 (UMLS CUI [3,1])
C0205390 (UMLS CUI [3,2])
C0536495 (UMLS CUI [3,3])
C0231242 (UMLS CUI [4,1])
C0205390 (UMLS CUI [4,2])
C0008809 (UMLS CUI [4,3])
Code List
Fluorochinolones (ciprofloxacin, moxifloxacin, levofloxacin)
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item Group
Complicated phase: Treatments received, Antifungals
C0231242 (UMLS CUI-1)
C0205390 (UMLS CUI-2)
C0003308 (UMLS CUI-3)
Item
Itraconazole
integer
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0064113 (UMLS CUI [1,3])
Code List
Itraconazole
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Posaconazole
integer
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0936148 (UMLS CUI [1,3])
Code List
Posaconazole
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Other systemically active antifungals
integer
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0003308 (UMLS CUI [1,3])
C0205394 (UMLS CUI [1,4])
C1515119 (UMLS CUI [1,5])
Code List
Other systemically active antifungals
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item Group
Treatments received, Immunomodulators
C0231242 (UMLS CUI-1)
C0205390 (UMLS CUI-2)
C1527392 (UMLS CUI-3)
Item
Steroids > 0.5 mg/kg prednisone equivalents
integer
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0038317 (UMLS CUI [1,3])
C0444956 (UMLS CUI [1,4])
Code List
Steroids > 0.5 mg/kg prednisone equivalents
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Steroids <= 0.5 mg/kg prednisone equivalents
integer
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0038317 (UMLS CUI [1,3])
C0445550 (UMLS CUI [1,4])
Code List
Steroids <= 0.5 mg/kg prednisone equivalents
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
IL-6-receptor antagonist (tocilizumab)
integer
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C3819026 (UMLS CUI [1,3])
C0231242 (UMLS CUI [2,1])
C0205390 (UMLS CUI [2,2])
C1609165 (UMLS CUI [2,3])
Code List
IL-6-receptor antagonist (tocilizumab)
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
CNI or mTor inhibitors (e.g. cyclosporin A, tacrolimus, sirolimus, everolimus)
integer
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C1562036 (UMLS CUI [1,3])
C0231242 (UMLS CUI [2,1])
C0205390 (UMLS CUI [2,2])
C2746052 (UMLS CUI [2,3])
C0231242 (UMLS CUI [3,1])
C0205390 (UMLS CUI [3,2])
C0541315 (UMLS CUI [3,3])
C0231242 (UMLS CUI [4,1])
C0205390 (UMLS CUI [4,2])
C0072980 (UMLS CUI [4,3])
C0231242 (UMLS CUI [5,1])
C0205390 (UMLS CUI [5,2])
C0010592 (UMLS CUI [5,3])
C0231242 (UMLS CUI [6,1])
C0205390 (UMLS CUI [6,2])
C0085149 (UMLS CUI [6,3])
Code List
CNI or mTor inhibitors (e.g. cyclosporin A, tacrolimus, sirolimus, everolimus)
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Anti-TNF-alpha inhibitors (e.g. adalimumab, etanercept)
integer
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C3653350 (UMLS CUI [1,3])
C0231242 (UMLS CUI [2,1])
C0205390 (UMLS CUI [2,2])
C1122087 (UMLS CUI [2,3])
C0231242 (UMLS CUI [3,1])
C0205390 (UMLS CUI [3,2])
C0717758 (UMLS CUI [3,3])
Code List
Anti-TNF-alpha inhibitors (e.g. adalimumab, etanercept)
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Il1-receptor antagonists
integer
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C2917260 (UMLS CUI [1,3])
Code List
Il1-receptor antagonists
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
JAK inhibitors (Ruxolitinib)
integer
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C3854325 (UMLS CUI [1,3])
C0231242 (UMLS CUI [2,1])
C0205390 (UMLS CUI [2,2])
C2931926 (UMLS CUI [2,3])
Code List
JAK inhibitors (Ruxolitinib)
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Immunoglobulines
integer
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0021027 (UMLS CUI [1,3])
Code List
Immunoglobulines
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Interferone (any)
integer
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0021747 (UMLS CUI [1,3])
Code List
Interferone (any)
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Apheresis therapy
integer
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0005791 (UMLS CUI [1,3])
Code List
Apheresis therapy
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Vitamin D
integer
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0042866 (UMLS CUI [1,3])
C1527392 (UMLS CUI [1,4])
Code List
Vitamin D
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Zinc
integer
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0043481 (UMLS CUI [1,3])
C1527392 (UMLS CUI [1,4])
Code List
Zinc
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Convalescent plasma
integer
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0032105 (UMLS CUI [1,3])
C0740326 (UMLS CUI [1,4])
Code List
Convalescent plasma
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item Group
Complicated phase: Treatments received, Heart / circulatory medication
C0231242 (UMLS CUI-1)
C0205390 (UMLS CUI-2)
C0007226 (UMLS CUI-3)
C0013227 (UMLS CUI-4)
Item
ACE inhibitors (e.g. enalapril, captopril, most drugs ending on -pril)
integer
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0003015 (UMLS CUI [1,3])
C0231242 (UMLS CUI [2,1])
C0205390 (UMLS CUI [2,2])
C0006938 (UMLS CUI [2,3])
C0231242 (UMLS CUI [3,1])
C0205390 (UMLS CUI [3,2])
C0014025 (UMLS CUI [3,3])
Code List
ACE inhibitors (e.g. enalapril, captopril, most drugs ending on -pril)
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Betablockers (e.g. bisoprolol, metoprolol, most drugs ending on -prolol)
integer
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0053799 (UMLS CUI [1,3])
C0231242 (UMLS CUI [2,1])
C0205390 (UMLS CUI [2,2])
C0025859 (UMLS CUI [2,3])
C0231242 (UMLS CUI [3,1])
C0205390 (UMLS CUI [3,2])
C0304516 (UMLS CUI [3,3])
Code List
Betablockers (e.g. bisoprolol, metoprolol, most drugs ending on -prolol)
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
AT-II-receptor-1-antagonists (e.g. candesartan, losartan, most drugs ending on -sartan)
integer
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0521942 (UMLS CUI [1,3])
C0231242 (UMLS CUI [2,1])
C0205390 (UMLS CUI [2,2])
C0126174 (UMLS CUI [2,3])
C0231242 (UMLS CUI [3,1])
C0205390 (UMLS CUI [3,2])
C0717550 (UMLS CUI [3,3])
Code List
AT-II-receptor-1-antagonists (e.g. candesartan, losartan, most drugs ending on -sartan)
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Other antihypertensives
integer
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0003364 (UMLS CUI [1,3])
C0205394 (UMLS CUI [1,4])
Code List
Other antihypertensives
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Statines (e.g. atorvastatin, pravastatin, most drugs ending on -statin)
integer
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0286651 (UMLS CUI [1,3])
C0231242 (UMLS CUI [2,1])
C0205390 (UMLS CUI [2,2])
C0085542 (UMLS CUI [2,3])
C0231242 (UMLS CUI [3,1])
C0205390 (UMLS CUI [3,2])
C0360714 (UMLS CUI [3,3])
Code List
Statines (e.g. atorvastatin, pravastatin, most drugs ending on -statin)
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Anti-arrhythmics (e.g. digitoxine, verapamil)
integer
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0003195 (UMLS CUI [1,3])
C0231242 (UMLS CUI [2,1])
C0205390 (UMLS CUI [2,2])
C0042523 (UMLS CUI [2,3])
C0231242 (UMLS CUI [3,1])
C0205390 (UMLS CUI [3,2])
C0012258 (UMLS CUI [3,3])
Code List
Anti-arrhythmics (e.g. digitoxine, verapamil)
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Adrenaline or other sympathomimetics (e.g. noradrenaline, dobutamine, epinephrine)
integer
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0014563 (UMLS CUI [1,3])
C0231242 (UMLS CUI [2,1])
C0205390 (UMLS CUI [2,2])
C0012963 (UMLS CUI [2,3])
C0231242 (UMLS CUI [3,1])
C0205390 (UMLS CUI [3,2])
C0028351 (UMLS CUI [3,3])
C0231242 (UMLS CUI [4,1])
C0205390 (UMLS CUI [4,2])
C0205394 (UMLS CUI [4,3])
C0039052 (UMLS CUI [4,4])
Code List
Adrenaline or other sympathomimetics (e.g. noradrenaline, dobutamine, epinephrine)
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Vasopressin (e.g. argipressin, arginine vasopressin)
integer
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0042413 (UMLS CUI [1,3])
C0231242 (UMLS CUI [2,1])
C0205390 (UMLS CUI [2,2])
C0003779 (UMLS CUI [2,3])
Code List
Vasopressin (e.g. argipressin, arginine vasopressin)
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Iloprost
integer
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0079594 (UMLS CUI [1,3])
Code List
Iloprost
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Nitrates (nitroglycerin, ISMN, Molsidomin, NO)
integer
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C3654024 (UMLS CUI [1,3])
C0231242 (UMLS CUI [2,1])
C0205390 (UMLS CUI [2,2])
C0017887 (UMLS CUI [2,3])
C0231242 (UMLS CUI [3,1])
C0205390 (UMLS CUI [3,2])
C0064079 (UMLS CUI [3,3])
C0231242 (UMLS CUI [4,1])
C0205390 (UMLS CUI [4,2])
C0026400 (UMLS CUI [4,3])
C0231242 (UMLS CUI [5,1])
C0205390 (UMLS CUI [5,2])
C0028215 (UMLS CUI [5,3])
Code List
Nitrates (nitroglycerin, ISMN, Molsidomin, NO)
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Aviptadil (VIP analog)
integer
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C1098515 (UMLS CUI [1,3])
C0231242 (UMLS CUI [2,1])
C0205390 (UMLS CUI [2,2])
C0042395 (UMLS CUI [2,3])
C0243071 (UMLS CUI [2,4])
Code List
Aviptadil (VIP analog)
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Colchicine
integer
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0009262 (UMLS CUI [1,3])
Code List
Colchicine
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item Group
Complicated phase: Non-oral anticoagulants
C0231242 (UMLS CUI-1)
C0205390 (UMLS CUI-2)
C0003280 (UMLS CUI-3)
C0332300 (UMLS CUI-4)
C0442027 (UMLS CUI-5)
CO (Heparin, prophylactic)
Item
Heparin, prophylactic dose
boolean
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0019134 (UMLS CUI [1,3])
C0199176 (UMLS CUI [1,4])
CO (Heparin, therapeutic)
Item
Heparin, therapeutic dose
boolean
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0019134 (UMLS CUI [1,3])
C0302350 (UMLS CUI [1,4])
CO (Heparin intermediate)
Item
Heparin, subtherapeutic dose (but higher than prophylactic dose)
boolean
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0019134 (UMLS CUI [1,3])
C0205103 (UMLS CUI [1,4])
C0087111 (UMLS CUI [1,5])
C0199176 (UMLS CUI [1,6])
CO (Low molecular weight heparin, prophylactic (enoxaparin, fraxiparin, etc.))
Item
Low molecular weight heparin (enoxaparin, fraxiparin, etc.), prophylactic dose
boolean
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0019139 (UMLS CUI [1,3])
C0199176 (UMLS CUI [1,4])
C0231242 (UMLS CUI [2,1])
C0205390 (UMLS CUI [2,2])
C0206460 (UMLS CUI [2,3])
C0199176 (UMLS CUI [2,4])
C0231242 (UMLS CUI [3,1])
C0205390 (UMLS CUI [3,2])
C0878354 (UMLS CUI [3,3])
C0199176 (UMLS CUI [3,4])
CO (Low molecular weight heparin, therapeutic (enoxaparin, fraxiparin, etc.))
Item
Low molecular weight heparin (enoxaparin, fraxiparin, etc.), therapeutic dose
boolean
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0019139 (UMLS CUI [1,3])
C0302350 (UMLS CUI [1,4])
C0231242 (UMLS CUI [2,1])
C0205390 (UMLS CUI [2,2])
C0206460 (UMLS CUI [2,3])
C0302350 (UMLS CUI [2,4])
C0231242 (UMLS CUI [3,1])
C0205390 (UMLS CUI [3,2])
C0878354 (UMLS CUI [3,3])
C0302350 (UMLS CUI [3,4])
CO (Low molecular weight heparin, intermediate (enoxaparin, fraxiparin, etc.))
Item
Low molecular weight heparin (enoxaparin, fraxiparin, etc.), subtherapeutic dose (but higher than prophylactic dose)
boolean
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0019139 (UMLS CUI [1,3])
C0205103 (UMLS CUI [1,4])
C0087111 (UMLS CUI [1,5])
C0199176 (UMLS CUI [1,6])
C0231242 (UMLS CUI [2,1])
C0205390 (UMLS CUI [2,2])
C0206460 (UMLS CUI [2,3])
C0205103 (UMLS CUI [2,4])
C0087111 (UMLS CUI [2,5])
C0199176 (UMLS CUI [2,6])
C0231242 (UMLS CUI [3,1])
C0205390 (UMLS CUI [3,2])
C0878354 (UMLS CUI [3,3])
C0205103 (UMLS CUI [3,4])
C0087111 (UMLS CUI [3,5])
C0199176 (UMLS CUI [3,6])
CO (Argatroban)
Item
Argatroban
boolean
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0048470 (UMLS CUI [1,3])
Item Group
Complicated phase: Oral anticoagulants
C0231242 (UMLS CUI-1)
C0205390 (UMLS CUI-2)
C0354604 (UMLS CUI-3)
CO (Warfarin / marcumar)
Item
Warfarin / marcumar
boolean
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0043031 (UMLS CUI [1,3])
C0231242 (UMLS CUI [2,1])
C0205390 (UMLS CUI [2,2])
C0918269 (UMLS CUI [2,3])
CO (New / direct oral anticoagulants(rivaroxaban, apixaban, dabigatran))
Item
New / direct oral anticoagulants (rivaroxaban, apixaban, dabigatran)
boolean
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0360593 (UMLS CUI [1,3])
C0354604 (UMLS CUI [1,4])
C0231242 (UMLS CUI [2,1])
C0205390 (UMLS CUI [2,2])
C1739768 (UMLS CUI [2,3])
C0231242 (UMLS CUI [3,1])
C0205390 (UMLS CUI [3,2])
C1831808 (UMLS CUI [3,3])
C0231242 (UMLS CUI [4,1])
C0205390 (UMLS CUI [4,2])
C2348066 (UMLS CUI [4,3])
Item Group
Complicated phase: Platelet aggregation inhibition
C0231242 (UMLS CUI-1)
C0205390 (UMLS CUI-2)
C0032177 (UMLS CUI-3)
CO (Aspirin)
Item
Aspirin
boolean
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0004057 (UMLS CUI [1,3])
CO (ADP receptor inhibitors)
Item
ADP receptor inhibitors (Clopidogrel, Cangrelor, Ticagrelor)
boolean
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C1373149 (UMLS CUI [1,3])
C0231242 (UMLS CUI [2,1])
C0205390 (UMLS CUI [2,2])
C0070166 (UMLS CUI [2,3])
C0231242 (UMLS CUI [3,1])
C0205390 (UMLS CUI [3,2])
C1121991 (UMLS CUI [3,3])
C0231242 (UMLS CUI [4,1])
C0205390 (UMLS CUI [4,2])
C1999375 (UMLS CUI [4,3])
CO (Glycoprotein IIB/IIIA inhibitors)
Item
Glycoprotein IIB/IIIA inhibitors
boolean
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C1373125 (UMLS CUI [1,3])
Item Group
Complicated phase: Further anticoagulation / platelet aggregation inhibition
C0231242 (UMLS CUI-1)
C0205390 (UMLS CUI-2)
C0205394 (UMLS CUI-3)
C0003281 (UMLS CUI-4)
C0032177 (UMLS CUI-5)
CO (Other anticoagulation/platelet aggregation inhibition)
Item
Other anticoagulation/platelet aggregation inhibition
boolean
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0205394 (UMLS CUI [1,3])
C0003281 (UMLS CUI [1,4])
C0231242 (UMLS CUI [2,1])
C0205390 (UMLS CUI [2,2])
C0205394 (UMLS CUI [2,3])
C0032177 (UMLS CUI [2,4])
CO (indicate other anticoagulation/platelet aggregation inhibition)
Item
Indicate other anticoagulation/platelet aggregation inhibition
text
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0205394 (UMLS CUI [1,3])
C0003281 (UMLS CUI [1,4])
C1521902 (UMLS CUI [1,5])
C0231242 (UMLS CUI [2,1])
C0205390 (UMLS CUI [2,2])
C0205394 (UMLS CUI [2,3])
C0032177 (UMLS CUI [2,4])
C1521902 (UMLS CUI [2,5])
CO (No anticoagulation/platelet aggregation inhibition)
Item
No anticoagulation/platelet aggregation inhibition
boolean
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0549184 (UMLS CUI [1,3])
C0003281 (UMLS CUI [1,4])
C0231242 (UMLS CUI [2,1])
C0205390 (UMLS CUI [2,2])
C0549184 (UMLS CUI [2,3])
C0032177 (UMLS CUI [2,4])
CO (Unknown anticoagulation/platelet aggregation inhibition)
Item
Unknown anticoagulation/platelet aggregation inhibition
boolean
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0439673 (UMLS CUI [1,3])
C0003281 (UMLS CUI [1,4])
C0231242 (UMLS CUI [2,1])
C0205390 (UMLS CUI [2,2])
C0439673 (UMLS CUI [2,3])
C0032177 (UMLS CUI [2,4])
Item Group
Complicated phase: Other COVID-19 related therapy
C0231242 (UMLS CUI-1)
C0205390 (UMLS CUI-2)
C5203670 (UMLS CUI-3)
C0087111 (UMLS CUI-4)
C0205394 (UMLS CUI-5)
Item
Mucolytic agents
integer
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0026698 (UMLS CUI [1,3])
Code List
Mucolytic agents
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Nonsteroidal anti-inflammatory drugs (e.g. aspirin, ibuprofen, naproxen, diclofenac, coxibs)
integer
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0003211 (UMLS CUI [1,3])
C0231242 (UMLS CUI [2,1])
C0205390 (UMLS CUI [2,2])
C0004057 (UMLS CUI [2,3])
C0231242 (UMLS CUI [3,1])
C0205390 (UMLS CUI [3,2])
C0020740 (UMLS CUI [3,3])
C0231242 (UMLS CUI [4,1])
C0205390 (UMLS CUI [4,2])
C0027396 (UMLS CUI [4,3])
C0231242 (UMLS CUI [5,1])
C0205390 (UMLS CUI [5,2])
C0012091 (UMLS CUI [5,3])
C0231242 (UMLS CUI [6,1])
C0205390 (UMLS CUI [6,2])
C1257954 (UMLS CUI [6,3])
Code List
Nonsteroidal anti-inflammatory drugs (e.g. aspirin, ibuprofen, naproxen, diclofenac, coxibs)
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Paracetamol
integer
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0000970 (UMLS CUI [1,3])
Code List
Paracetamol
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Metamizole
integer
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C3714569 (UMLS CUI [1,3])
Code List
Metamizole
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Other COVID-19 related drug therapy
integer
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C5203670 (UMLS CUI [1,3])
C0087111 (UMLS CUI [1,4])
C0205394 (UMLS CUI [1,5])
Code List
Other COVID-19 related drug therapy
CL Item
Yes, please specify (1)
CL Item
No (2)
CL Item
Unknown (3)
CO (Other COVID-19 related drug therapy_text)
Item
Indicate other COVID-19 related drug therapy
text
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C5203670 (UMLS CUI [1,3])
C0087111 (UMLS CUI [1,4])
C0205394 (UMLS CUI [1,5])
C1521902 (UMLS CUI [1,6])
Item Group
Complicated phase: Co/Superinfections
C0231242 (UMLS CUI-1)
C0205390 (UMLS CUI-2)
C0275524 (UMLS CUI-3)
C0038826 (UMLS CUI-4)
CO (Proven bacterial infection)
Item
Proven bacterial infection
boolean
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0004623 (UMLS CUI [1,3])
C0456369 (UMLS CUI [1,4])
CO (indicate proven bacterial infection)
Item
Indicate site and respective pathogen of proven bacterial infection
text
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0004623 (UMLS CUI [1,3])
C0456369 (UMLS CUI [1,4])
C1521902 (UMLS CUI [1,5])
CO (probable or suspected bacterial infection)
Item
Probable or suspected bacterial infection
boolean
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0004623 (UMLS CUI [1,3])
C0332147 (UMLS CUI [1,4])
C0231242 (UMLS CUI [2,1])
C0205390 (UMLS CUI [2,2])
C0004623 (UMLS CUI [2,3])
C0332148 (UMLS CUI [2,4])
CO (Indicate probable or suspected bacterial infection)
Item
Indicate site and respective pathogen of probable or suspected bacterial infection
text
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0004623 (UMLS CUI [1,3])
C0332147 (UMLS CUI [1,4])
C1521902 (UMLS CUI [1,5])
C0231242 (UMLS CUI [2,1])
C0205390 (UMLS CUI [2,2])
C0004623 (UMLS CUI [2,3])
C0332148 (UMLS CUI [2,4])
C1521902 (UMLS CUI [2,5])
CO (Proven fungal infection)
Item
Proven fungal infection
boolean
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0026946 (UMLS CUI [1,3])
C0456369 (UMLS CUI [1,4])
CO (indicate proven fungal infection)
Item
Indicate site and respective pathogen of proven fungal infection
text
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0026946 (UMLS CUI [1,3])
C0456369 (UMLS CUI [1,4])
C1521902 (UMLS CUI [1,5])
CO (probable or suspected fungal infection)
Item
Probable or suspected fungal infection
boolean
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0026946 (UMLS CUI [1,3])
C0332147 (UMLS CUI [1,4])
C0231242 (UMLS CUI [2,1])
C0205390 (UMLS CUI [2,2])
C0026946 (UMLS CUI [2,3])
C0332148 (UMLS CUI [2,4])
CO (Indicate probable or suspected fungal infection)
Item
Indicate site and respective pathogen of probable or suspected fungal infection
text
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0026946 (UMLS CUI [1,3])
C0332147 (UMLS CUI [1,4])
C1521902 (UMLS CUI [1,5])
C0231242 (UMLS CUI [2,1])
C0205390 (UMLS CUI [2,2])
C0026946 (UMLS CUI [2,3])
C0332148 (UMLS CUI [2,4])
C1521902 (UMLS CUI [2,5])
CO (No Co/Superinfection)
Item
None
boolean
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0549184 (UMLS CUI [1,3])
C0038826 (UMLS CUI [1,4])
C0231242 (UMLS CUI [2,1])
C0205390 (UMLS CUI [2,2])
C0549184 (UMLS CUI [2,3])
C0275524 (UMLS CUI [2,4])
CO (Unknown Co/superinfection)
Item
Unknown
boolean
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0439673 (UMLS CUI [1,3])
C0038826 (UMLS CUI [1,4])
C0231242 (UMLS CUI [2,1])
C0205390 (UMLS CUI [2,2])
C0439673 (UMLS CUI [2,3])
C0275524 (UMLS CUI [2,4])
Item Group
Complicated phase: Antibacterial treatment: Betalactams
C0231242 (UMLS CUI-1)
C0205390 (UMLS CUI-2)
C0279516 (UMLS CUI-3)
C0087111 (UMLS CUI-4)
C0282215 (UMLS CUI-5)
Item
Penicillins/ aminopenicilins
integer
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0030842 (UMLS CUI [1,3])
C0231242 (UMLS CUI [2,1])
C0205390 (UMLS CUI [2,2])
C0304324 (UMLS CUI [2,3])
Code List
Penicillins/ aminopenicilins
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Cephalosporins I-III
integer
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0304317 (UMLS CUI [1,3])
C0231242 (UMLS CUI [2,1])
C0205390 (UMLS CUI [2,2])
C0304319 (UMLS CUI [2,3])
C0231242 (UMLS CUI [3,1])
C0205390 (UMLS CUI [3,2])
C0304320 (UMLS CUI [3,3])
Code List
Cephalosporins I-III
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Carbapenems (meropenem, imipenem, ertapenem, doripenem)
integer
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0006968 (UMLS CUI [1,3])
C0231242 (UMLS CUI [2,1])
C0205390 (UMLS CUI [2,2])
C0066005 (UMLS CUI [2,3])
C0231242 (UMLS CUI [3,1])
C0205390 (UMLS CUI [3,2])
C0020933 (UMLS CUI [3,3])
C0231242 (UMLS CUI [4,1])
C0205390 (UMLS CUI [4,2])
C1120106 (UMLS CUI [4,3])
C0231242 (UMLS CUI [5,1])
C0205390 (UMLS CUI [5,2])
C0389169 (UMLS CUI [5,3])
Code List
Carbapenems (meropenem, imipenem, ertapenem, doripenem)
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Piperacillin/tazobactam
integer
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0250480 (UMLS CUI [1,3])
Code List
Piperacillin/tazobactam
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
New betalactams for multi-resistent bacteria (ceftazidime/avibactam, ceftolozane/tazobactam, cefiderocol)
integer
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0205314 (UMLS CUI [1,3])
C0282215 (UMLS CUI [1,4])
C3826980 (UMLS CUI [1,5])
C0231242 (UMLS CUI [2,1])
C0205390 (UMLS CUI [2,2])
C3656596 (UMLS CUI [2,3])
C0231242 (UMLS CUI [3,1])
C0205390 (UMLS CUI [3,2])
C3656593 (UMLS CUI [3,3])
C0231242 (UMLS CUI [4,1])
C0205390 (UMLS CUI [4,2])
C4548369 (UMLS CUI [4,3])
Code List
New betalactams for multi-resistent bacteria (ceftazidime/avibactam, ceftolozane/tazobactam, cefiderocol)
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item Group
Complicated phase: Antibacterial treatment: Macrolides
C0231242 (UMLS CUI-1)
C0205390 (UMLS CUI-2)
C0279516 (UMLS CUI-3)
C0087111 (UMLS CUI-4)
C0003240 (UMLS CUI-5)
Item
Azithromycin
integer
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0052796 (UMLS CUI [1,3])
Code List
Azithromycin
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Other macrolide (erythromycin, clarithromycin, roxithromycin)
integer
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0003240 (UMLS CUI [1,3])
C0205394 (UMLS CUI [1,4])
C0231242 (UMLS CUI [2,1])
C0205390 (UMLS CUI [2,2])
C0014806 (UMLS CUI [2,3])
C0231242 (UMLS CUI [3,1])
C0205390 (UMLS CUI [3,2])
C0055856 (UMLS CUI [3,3])
C0231242 (UMLS CUI [4,1])
C0205390 (UMLS CUI [4,2])
C0035891 (UMLS CUI [4,3])
Code List
Other macrolide (erythromycin, clarithromycin, roxithromycin)
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item Group
Complicated phase: Antibacterial treatment: Other antibacterial treatment
C0231242 (UMLS CUI-1)
C0205390 (UMLS CUI-2)
C0279516 (UMLS CUI-3)
C0087111 (UMLS CUI-4)
C0205394 (UMLS CUI-5)
Item
Glycopeptides (vancomycin, teicoplanin)
integer
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0017953 (UMLS CUI [1,3])
C0231242 (UMLS CUI [2,1])
C0205390 (UMLS CUI [2,2])
C0042313 (UMLS CUI [2,3])
C0231242 (UMLS CUI [3,1])
C0205390 (UMLS CUI [3,2])
C0145106 (UMLS CUI [3,3])
Code List
Glycopeptides (vancomycin, teicoplanin)
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Other gram-positive active drugs for multiresistant bacteria (e.g. linezolid, daptomycin)
integer
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0205394 (UMLS CUI [1,3])
C0018154 (UMLS CUI [1,4])
C3826980 (UMLS CUI [1,5])
C0231242 (UMLS CUI [2,1])
C0205390 (UMLS CUI [2,2])
C0663241 (UMLS CUI [2,3])
C0231242 (UMLS CUI [3,1])
C0205390 (UMLS CUI [3,2])
C0057144 (UMLS CUI [3,3])
Code List
Other gram-positive active drugs for multiresistant bacteria (e.g. linezolid, daptomycin)
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Fluorochinolones (ciprofloxacin, moxifloxacin, levofloxacin)
integer
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0034428 (UMLS CUI [1,3])
C0231242 (UMLS CUI [2,1])
C0205390 (UMLS CUI [2,2])
C0008809 (UMLS CUI [2,3])
C0231242 (UMLS CUI [3,1])
C0205390 (UMLS CUI [3,2])
C0536495 (UMLS CUI [3,3])
C0231242 (UMLS CUI [4,1])
C0205390 (UMLS CUI [4,2])
C0282386 (UMLS CUI [4,3])
Code List
Fluorochinolones (ciprofloxacin, moxifloxacin, levofloxacin)
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Other antibacterial treatment
integer
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0279516 (UMLS CUI [1,3])
C0205394 (UMLS CUI [1,4])
Code List
Other antibacterial treatment
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Indicate other antibacterial treatment
integer
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0279516 (UMLS CUI [1,3])
C0205394 (UMLS CUI [1,4])
C1521902 (UMLS CUI [1,5])
Code List
Indicate other antibacterial treatment
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item Group
Complicated phase: Complications, Thrombotic and thromboembolic manifestations
C0231242 (UMLS CUI-1)
C0205390 (UMLS CUI-2)
C0009566 (UMLS CUI-3)
C0040053 (UMLS CUI-4)
C0040038 (UMLS CUI-5)
Item
Abdominal thrombosis/thromboembolism (venous or arterial)
integer
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0151942 (UMLS CUI [1,3])
C0000726 (UMLS CUI [1,4])
C0231242 (UMLS CUI [2,1])
C0205390 (UMLS CUI [2,2])
C0042487 (UMLS CUI [2,3])
C0000726 (UMLS CUI [2,4])
C0231242 (UMLS CUI [3,1])
C0205390 (UMLS CUI [3,2])
C3544094 (UMLS CUI [3,3])
C0000726 (UMLS CUI [3,4])
C0231242 (UMLS CUI [4,1])
C0205390 (UMLS CUI [4,2])
C1861172 (UMLS CUI [4,3])
C0000726 (UMLS CUI [4,4])
Code List
Abdominal thrombosis/thromboembolism (venous or arterial)
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Myocardial infarction
integer
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0027051 (UMLS CUI [1,3])
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Venous thromboses, e.g. leg vein thrombosis
integer
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0042487 (UMLS CUI [1,3])
C0231242 (UMLS CUI [2,1])
C0205390 (UMLS CUI [2,2])
C0149871 (UMLS CUI [2,3])
Code List
Venous thromboses, e.g. leg vein thrombosis
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Pulmonary embolism
integer
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0034065 (UMLS CUI [1,3])
Code List
Pulmonary embolism
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Microangiopathies and microthromboses
integer
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C2717961 (UMLS CUI [1,3])
C0231242 (UMLS CUI [2,1])
C0205390 (UMLS CUI [2,2])
C3686869 (UMLS CUI [2,3])
Code List
Microangiopathies and microthromboses
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item Group
Complicated phase: Complications, Neurological
C0231242 (UMLS CUI-1)
C0205390 (UMLS CUI-2)
C0009566 (UMLS CUI-3)
C0027763 (UMLS CUI-4)
Item
Intracerebral bleeding
integer
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C2937358 (UMLS CUI [1,3])
Code List
Intracerebral bleeding
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Ischemic Stroke
integer
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0948008 (UMLS CUI [1,3])
Code List
Ischemic Stroke
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Meningitis / Encephalitis
integer
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0497299 (UMLS CUI [1,3])
Code List
Meningitis / Encephalitis
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Critical Illness Myopathy (CIM)
integer
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0010340 (UMLS CUI [1,3])
C0026848 (UMLS CUI [1,4])
Code List
Critical Illness Myopathy (CIM)
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Critical Illness Polyneuropathy (CIP)
integer
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0010340 (UMLS CUI [1,3])
C0152025 (UMLS CUI [1,4])
Code List
Critical Illness Polyneuropathy (CIP)
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Seizure
integer
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0036572 (UMLS CUI [1,3])
Code List
Seizure
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item Group
Ischemic stroke: TOAST classification
C0231242 (UMLS CUI-1)
C0205390 (UMLS CUI-2)
C0948008 (UMLS CUI-3)
C1710306 (UMLS CUI-4)
Item
State most likely cause of ischemic stroke (TOAST)
integer
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0948008 (UMLS CUI [1,3])
C1710306 (UMLS CUI [1,4])
C0085978 (UMLS CUI [1,5])
Code List
State most likely cause of ischemic stroke (TOAST)
CL Item
Cardioembolic (CE) (1)
CL Item
Large-arteryatherosclerosis (LAA) (2)
CL Item
Small artery occlusion (SAO) (3)
CL Item
Other causes (OTH) (4)
CL Item
Undefined (UND) (5)
CL Item
Unknown (6)
Item Group
Ischemic stroke: NIHSS score in acute phase
C0231242 (UMLS CUI-1)
C0205390 (UMLS CUI-2)
C0948008 (UMLS CUI-3)
C4269147 (UMLS CUI-4)
C0439557 (UMLS CUI-5)
CO (Indicate NIHSS score in acute phase)
Item
Indicate NIHSS score in acute phase
text
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0948008 (UMLS CUI [1,3])
C4269147 (UMLS CUI [1,4])
C0439557 (UMLS CUI [1,5])
Item Group
Complicated phase: Complications, Other
C0231242 (UMLS CUI-1)
C0205390 (UMLS CUI-2)
C0009566 (UMLS CUI-3)
C0205394 (UMLS CUI-4)
Item
Myocarditis
integer
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0027059 (UMLS CUI [1,3])
Code List
Myocarditis
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Vasculitis
integer
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0042384 (UMLS CUI [1,3])
Code List
Vasculitis
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Gastrointestinal bleeding
integer
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0017181 (UMLS CUI [1,3])
Code List
Gastrointestinal bleeding
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item
Other complication
integer
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0205394 (UMLS CUI [1,3])
C0009566 (UMLS CUI [1,4])
Code List
Other complication
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
CO (indicate other complication)
Item
Indicate other complication
text
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C0205394 (UMLS CUI [1,3])
C0009566 (UMLS CUI [1,4])
C1521902 (UMLS CUI [1,5])
Item Group
Acute kidney injury (KDIGO criteria)
C0231242 (UMLS CUI-1)
C0205390 (UMLS CUI-2)
C2609414 (UMLS CUI-3)
C0679228 (UMLS CUI-4)
Item
Acute kidney injury (KDIGO criteria)
integer
C0231242 (UMLS CUI [1,1])
C0205390 (UMLS CUI [1,2])
C2609414 (UMLS CUI [1,3])
C0679228 (UMLS CUI [1,4])
Code List
Acute kidney injury (KDIGO criteria)
CL Item
Stage I (1)
CL Item
Stage II (2)
CL Item
Stage III (3)
CL Item
None (4)
CL Item
Unknown (5)
Item Group
Complicated phase: SOFA score
C0231242 (UMLS CUI-1)
C0205390 (UMLS CUI-2)
C3494459 (UMLS CUI-3)
CO (worst SOFA)
Item
Complicated phase: SOFA score
integer
C3494459 (UMLS CUI [1,1])
C1522166 (UMLS CUI [1,2])
C0231242 (UMLS CUI [1,3])
C0205390 (UMLS CUI [1,4])
Item Group
Complicated phase: Is data entry for this section finished?
C4684556 (UMLS CUI-1)
C1828479 (UMLS CUI-2)
C0205197 (UMLS CUI-3)
Item
Complicated phase: Is data entry for this section finished?
integer
C4684556 (UMLS CUI [1,1])
C1828479 (UMLS CUI [1,2])
C0205197 (UMLS CUI [1,3])
Code List
Complicated phase: Is data entry for this section finished?
CL Item
Yes (1)
CL Item
No (2)

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