ID
42476
Beschrijving
Study Title: LEOSS: Lean European Open Survey on SARS-CoV-2 Infected Patients https://leoss.net Study Indication: COVID-19 Date: 19.03.2021 Published with permission by Prof. Dr. med. J.-J. Vehreschild. LEOSS, a multi-center cohort study, has been created to get more in-depth knowledge about the epidemiology and clinical course of patients infected with SARS-CoV-2. Initiated by the ESCMID Emerging Infections Task Force (EITaF) and the German Infectious Disease Society, and supported by all German Centers for Health Research (DZG), LEOSS has developed into an international network of contributors. Via an integrative research approach with anonymous recruitment and collection of routine data in an open science context, LEOSS is building a uniform clinical dataset and providing real-time analyses. For more information feel free to explore https://leoss.net/. Please note that only cases with known outcome are collected! Baseline / diagnosis is defined as the day the sample of the first positive SARS-CoV-2 result was taken. Criteria of the Uncomplicated Phase: Asymptomatic OR Symptoms of upper respiratory tract infection and/or Nausea, emesis, diarrhea and/or Fever Remember: The Uncomplicated Phase ends, if a previously febrile patient has no fever anymore and has completed 14 days of follow-up without entering Complicated or Critical Phase; then move to Recovery Phase. Also, as soon as one of the criteria of the Complicated or Critical Phase are fulfilled, Uncomplicated Phase ends; move over to there. If the patient has died, the phase ends with the death of the patient. If the patient has died, do not report terminal values, e.g. those recorded after switching off life-support or heart rate "0" after death of the patient. Criteria of the Complicated Phase: * Need for oxygen supplementation (In patients with prior oxygen home therapy, clinically meaningful increase in need for oxygenation.) * paO2 at room air < 70 mmHg * SO2 at room air < 90 % * GOT or GPT > 5x ULN * New cardiac arrhythmia * New pericardial effusion >1cm * New heart failure with pulmonary edema, congestive hepatopathy or peripheral edema Remember: The Complicated Phase ends, if none of the criteria for the Complicated Phase is fulfilled anymore AND the patient is free of fever; then move to Recovery Phase. Also, as soon as one of the criteria of the Critical Phase are fulfilled, Complicated Phase ends; move over to Critical Phase. If the patient has died, the phase ends with the death of the patient. If the patient has died, do not report terminal values, e.g. those recorded after switching off life-support or heart rate "0" after death of the patient. Criteria of the Critical Phase: * Need for catecholamines * Life-threatening cardiac arrhythmia * Mechanical ventilation (invasive or non-invasive) * Liver failure with Quick< 50% * qSOFA >= 2 * Renal failure in need of dialysis Remember: The Critical Phase ends as soon as none of the criteria for the Critical Phase is fulfilled anymore AND the patient is free of fever. If the patient has died, it ends with the death of the patient. If the patient has died, do not report terminal values, i.e. those recorded after turning off life-support or heart rate "0" after death of the patient. Criteria of the Recovery Phase: *Improvement by at least one phase, i.e. Critical to Complicated or Complicated to Uncomplicated * Defervescence Remember: Uncomplicated asymptomatic patients enter recovery phase after 14 days of observation without disease progression No further progression or re-hospitalization If a text field can't be filled out, note 'ND' (for not determined).
Link
Trefwoorden
Versies (3)
- 02-07-21 02-07-21 - Sarah Riepenhausen
- 15-07-21 15-07-21 - Sarah Riepenhausen
- 16-07-21 16-07-21 - Sarah Riepenhausen
Houder van rechten
LEOSS
Geüploaded op
16 juli 2021
DOI
10.21961/mdm:42476
Licentie
Creative Commons BY 4.0
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LEOSS: Lean European Open Survey on SARS-CoV-2 Infected Patients
Solid organ transplant sub-cohort
- StudyEvent: Baseline
- StudyEvent: Comorbidities and Pre-medication
- StudyEvent: Phases
- StudyEvent: Therapeutics
- StudyEvent: Diagnostics
Beschrijving
Most recent transplantation
Alias
- UMLS CUI-1
- C1513491
- UMLS CUI-2
- C0029216
Beschrijving
Immunsuppression at diagnosis of SARS-CoV-2
Alias
- UMLS CUI-1
- C5203676
- UMLS CUI-2
- C0021079
- UMLS CUI-3
- C0011900
Beschrijving
Indicate immunosuppressive medication at diagnosis of SARS-CoV-2.
Datatype
integer
Alias
- UMLS CUI [1]
- C0004482
Beschrijving
Indicate immunosuppressive medication at diagnosis of SARS-CoV-2.
Datatype
integer
Alias
- UMLS CUI [1]
- C1619962
Beschrijving
Indicate immunosuppressive medication at diagnosis of SARS-CoV-2.
Datatype
integer
Alias
- UMLS CUI [1]
- C0001617
Beschrijving
Indicate immunosuppressive medication at diagnosis of SARS-CoV-2.
Datatype
integer
Alias
- UMLS CUI [1]
- C0010592
Beschrijving
Indicate immunosuppressive medication at diagnosis of SARS-CoV-2.
Datatype
integer
Alias
- UMLS CUI [1]
- C2746052
Beschrijving
Indicate immunosuppressive medication at diagnosis of SARS-CoV-2.
Datatype
integer
Alias
- UMLS CUI [1]
- C0026933
- UMLS CUI [2]
- C0209368
Beschrijving
Indicate immunosuppressive medication at diagnosis of SARS-CoV-2.
Datatype
integer
Alias
- UMLS CUI [1]
- C0085149
Beschrijving
Indicate other immunosuppressive medication at diagnosis of SARS-CoV-2.
Datatype
integer
Alias
- UMLS CUI [1,1]
- C0205394
- UMLS CUI [1,2]
- C0021079
Beschrijving
Graft status before COVID-19
Alias
- UMLS CUI-1
- C0478647
- UMLS CUI-2
- C0332152
- UMLS CUI-3
- C5203676
Beschrijving
Indicate graft status before diagnosis of SARS-CoV-2.
Datatype
boolean
Alias
- UMLS CUI [1,1]
- C0478647
- UMLS CUI [1,2]
- C0205360
- UMLS CUI [1,3]
- C0449238
Beschrijving
Indicate graft status before diagnosis of SARS-CoV-2.
Datatype
boolean
Alias
- UMLS CUI [1,1]
- C0877542
- UMLS CUI [1,2]
- C0205191
- UMLS CUI [1,3]
- C0205309
Beschrijving
Indicate T-cell depleting therapy within last 6 month before diagnosis of SARS-CoV-2.
Datatype
boolean
Alias
- UMLS CUI [1,1]
- C0677960
- UMLS CUI [1,2]
- C0332185
Beschrijving
Indicate B-cell depleting therapy within last 6 month before diagnosis of SARS-CoV-2.
Datatype
boolean
Alias
- UMLS CUI [1,1]
- C1171324
- UMLS CUI [1,2]
- C0332185
Beschrijving
Recent steroid bolus therapy
Datatype
boolean
Alias
- UMLS CUI [1,1]
- C0149783
- UMLS CUI [1,2]
- C1705509
- UMLS CUI [1,3]
- C0332185
Beschrijving
Graft status unknown
Datatype
boolean
Alias
- UMLS CUI [1,1]
- C0439673
- UMLS CUI [1,2]
- C0478647
Beschrijving
Therapeutic measures of transplant specific therapy
Alias
- UMLS CUI-1
- C0087111
- UMLS CUI-2
- C0079809
- UMLS CUI-3
- C0029216
Beschrijving
Indicate therapeutic measures of transplant specific therapy during SARS-CoV-2 infection.
Datatype
integer
Alias
- UMLS CUI [1,1]
- C0004482
- UMLS CUI [1,2]
- C3174092
Beschrijving
Indicate therapeutic measures of transplant specific therapy during SARS-CoV-2 infection.
Datatype
integer
Alias
- UMLS CUI [1,1]
- C3174092
- UMLS CUI [1,2]
- C1619962
Beschrijving
Indicate therapeutic measures of transplant specific therapy during SARS-CoV-2 infection.
Datatype
integer
Alias
- UMLS CUI [1,1]
- C0001617
- UMLS CUI [1,2]
- C3174092
Beschrijving
Indicate therapeutic measures of transplant specific therapy during SARS-CoV-2 infection.
Datatype
integer
Alias
- UMLS CUI [1,1]
- C0010592
- UMLS CUI [1,2]
- C3174092
Beschrijving
Indicate therapeutic measures of transplant specific therapy during SARS-CoV-2 infection.
Datatype
integer
Alias
- UMLS CUI [1,1]
- C2746052
- UMLS CUI [1,2]
- C3174092
Beschrijving
Indicate therapeutic measures of transplant specific therapy during SARS-CoV-2 infection.
Datatype
integer
Alias
- UMLS CUI [1,1]
- C0026933
- UMLS CUI [1,2]
- C3174092
- UMLS CUI [2,1]
- C0209368
- UMLS CUI [2,2]
- C3174092
Beschrijving
Indicate therapeutic measures of transplant specific therapy during SARS-CoV-2 infection.
Datatype
integer
Alias
- UMLS CUI [1,1]
- C0085149
- UMLS CUI [1,2]
- C3174092
Beschrijving
Indicate other therapeutic measures of transplant specific therapy during SARS-CoV-2 infection.
Datatype
integer
Alias
- UMLS CUI [1,1]
- C0205394
- UMLS CUI [1,2]
- C0087111
- UMLS CUI [1,3]
- C0029216
Beschrijving
Is data entry for this section finished?
Alias
- UMLS CUI-1
- C4684556
- UMLS CUI-2
- C1828479
- UMLS CUI-3
- C0205197
Similar models
Solid organ transplant sub-cohort
- StudyEvent: Baseline
- StudyEvent: Comorbidities and Pre-medication
- StudyEvent: Phases
- StudyEvent: Therapeutics
- StudyEvent: Diagnostics
C0332307 (UMLS CUI-2)
C0205245 (UMLS CUI-3)
C0029216 (UMLS CUI [1,2])
C0205245 (UMLS CUI [1,3])
C0029216 (UMLS CUI [1,2])
C0205245 (UMLS CUI [1,3])
C0029216 (UMLS CUI [1,2])
C0205245 (UMLS CUI [1,3])
C0029216 (UMLS CUI [1,2])
C0205245 (UMLS CUI [1,3])
C0029216 (UMLS CUI [1,2])
C0205245 (UMLS CUI [1,3])
C0029216 (UMLS CUI [1,2])
C0205245 (UMLS CUI [1,3])
C0029216 (UMLS CUI [1,2])
C0205245 (UMLS CUI [1,3])
C0029216 (UMLS CUI-2)
C1513491 (UMLS CUI [1,2])
C0029216 (UMLS CUI [1,3])
C0021079 (UMLS CUI-2)
C0011900 (UMLS CUI-3)
C0209368 (UMLS CUI [2])
C0021079 (UMLS CUI [1,2])
C0332152 (UMLS CUI-2)
C5203676 (UMLS CUI-3)
C0205360 (UMLS CUI [1,2])
C0449238 (UMLS CUI [1,3])
C0205191 (UMLS CUI [1,2])
C0205309 (UMLS CUI [1,3])
C0332185 (UMLS CUI [1,2])
C0332185 (UMLS CUI [1,2])
C1705509 (UMLS CUI [1,2])
C0332185 (UMLS CUI [1,3])
C0478647 (UMLS CUI [1,2])
C0079809 (UMLS CUI-2)
C0029216 (UMLS CUI-3)
C3174092 (UMLS CUI [1,2])
C3174092 (UMLS CUI [1,2])
C3174092 (UMLS CUI [1,2])
C3174092 (UMLS CUI [1,2])
C3174092 (UMLS CUI [1,2])
C0209368 (UMLS CUI [2,1])
C3174092 (UMLS CUI [2,2])
C0087111 (UMLS CUI [1,2])
C0029216 (UMLS CUI [1,3])
C1828479 (UMLS CUI-2)
C0205197 (UMLS CUI-3)
C1828479 (UMLS CUI [1,2])
C0205197 (UMLS CUI [1,3])