ID
42476
Beskrivning
Study Title: LEOSS: Lean European Open Survey on SARS-CoV-2 Infected Patients https://leoss.net Study Indication: COVID-19 Date: 19.03.2021 Published with permission by Prof. Dr. med. J.-J. Vehreschild. LEOSS, a multi-center cohort study, has been created to get more in-depth knowledge about the epidemiology and clinical course of patients infected with SARS-CoV-2. Initiated by the ESCMID Emerging Infections Task Force (EITaF) and the German Infectious Disease Society, and supported by all German Centers for Health Research (DZG), LEOSS has developed into an international network of contributors. Via an integrative research approach with anonymous recruitment and collection of routine data in an open science context, LEOSS is building a uniform clinical dataset and providing real-time analyses. For more information feel free to explore https://leoss.net/. Please note that only cases with known outcome are collected! Baseline / diagnosis is defined as the day the sample of the first positive SARS-CoV-2 result was taken. Criteria of the Uncomplicated Phase: Asymptomatic OR Symptoms of upper respiratory tract infection and/or Nausea, emesis, diarrhea and/or Fever Remember: The Uncomplicated Phase ends, if a previously febrile patient has no fever anymore and has completed 14 days of follow-up without entering Complicated or Critical Phase; then move to Recovery Phase. Also, as soon as one of the criteria of the Complicated or Critical Phase are fulfilled, Uncomplicated Phase ends; move over to there. If the patient has died, the phase ends with the death of the patient. If the patient has died, do not report terminal values, e.g. those recorded after switching off life-support or heart rate "0" after death of the patient. Criteria of the Complicated Phase: * Need for oxygen supplementation (In patients with prior oxygen home therapy, clinically meaningful increase in need for oxygenation.) * paO2 at room air < 70 mmHg * SO2 at room air < 90 % * GOT or GPT > 5x ULN * New cardiac arrhythmia * New pericardial effusion >1cm * New heart failure with pulmonary edema, congestive hepatopathy or peripheral edema Remember: The Complicated Phase ends, if none of the criteria for the Complicated Phase is fulfilled anymore AND the patient is free of fever; then move to Recovery Phase. Also, as soon as one of the criteria of the Critical Phase are fulfilled, Complicated Phase ends; move over to Critical Phase. If the patient has died, the phase ends with the death of the patient. If the patient has died, do not report terminal values, e.g. those recorded after switching off life-support or heart rate "0" after death of the patient. Criteria of the Critical Phase: * Need for catecholamines * Life-threatening cardiac arrhythmia * Mechanical ventilation (invasive or non-invasive) * Liver failure with Quick< 50% * qSOFA >= 2 * Renal failure in need of dialysis Remember: The Critical Phase ends as soon as none of the criteria for the Critical Phase is fulfilled anymore AND the patient is free of fever. If the patient has died, it ends with the death of the patient. If the patient has died, do not report terminal values, i.e. those recorded after turning off life-support or heart rate "0" after death of the patient. Criteria of the Recovery Phase: *Improvement by at least one phase, i.e. Critical to Complicated or Complicated to Uncomplicated * Defervescence Remember: Uncomplicated asymptomatic patients enter recovery phase after 14 days of observation without disease progression No further progression or re-hospitalization If a text field can't be filled out, note 'ND' (for not determined).
Länk
Nyckelord
Versioner (3)
- 2021-07-02 2021-07-02 - Sarah Riepenhausen
- 2021-07-15 2021-07-15 - Sarah Riepenhausen
- 2021-07-16 2021-07-16 - Sarah Riepenhausen
Rättsinnehavare
LEOSS
Uppladdad den
16 juli 2021
DOI
10.21961/mdm:42476
Licens
Creative Commons BY 4.0
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LEOSS: Lean European Open Survey on SARS-CoV-2 Infected Patients
Oncological Sub-cohort
- StudyEvent: Baseline
- StudyEvent: Comorbidities and Pre-medication
- StudyEvent: Phases
- StudyEvent: Therapeutics
- StudyEvent: Diagnostics
Beskrivning
Underlying disease: Solid tumors
Alias
- UMLS CUI-1
- C0277554
- UMLS CUI-2
- C0280100
- UMLS CUI-3
- C0205394
Beskrivning
Gastrointestinal cancer
Datatyp
boolean
Alias
- UMLS CUI [1]
- C0685938
Beskrivning
Lung cancer
Datatyp
boolean
Alias
- UMLS CUI [1]
- C0242379
Beskrivning
Head/Neck cancer
Datatyp
boolean
Alias
- UMLS CUI [1]
- C0278996
Beskrivning
Prostate cancer
Datatyp
boolean
Alias
- UMLS CUI [1]
- C0600139
Beskrivning
Bladder cancer
Datatyp
boolean
Alias
- UMLS CUI [1]
- C0005684
Beskrivning
Breast cancer
Datatyp
boolean
Alias
- UMLS CUI [1]
- C0678222
Beskrivning
Other gynecological cancer
Datatyp
boolean
Alias
- UMLS CUI [1,1]
- C1707251
- UMLS CUI [1,2]
- C0018417
Beskrivning
Malignant melanoma
Datatyp
boolean
Alias
- UMLS CUI [1]
- C0025202
Beskrivning
Underlying disease: Other underlying diseases
Alias
- UMLS CUI-1
- C0277554
- UMLS CUI-2
- C0205394
Beskrivning
Other underlying diseases
Datatyp
boolean
Alias
- UMLS CUI [1,1]
- C0205394
- UMLS CUI [1,2]
- C0277554
Beskrivning
Other underlying diseases_text
Datatyp
text
Alias
- UMLS CUI [1,1]
- C0205394
- UMLS CUI [1,2]
- C0277554
- UMLS CUI [1,3]
- C1521902
Beskrivning
Unknown underlying diseases
Datatyp
boolean
Alias
- UMLS CUI [1,1]
- C0439673
- UMLS CUI [1,2]
- C0277554
Beskrivning
Please specify the underlying NHL
Alias
- UMLS CUI-1
- C0277554
- UMLS CUI-2
- C0024305
- UMLS CUI-3
- C1521902
Beskrivning
If several NHLs have been diagnosed, please indicate all types.
Datatyp
boolean
Alias
- UMLS CUI [1]
- C1332225
Beskrivning
If several NHLs have been diagnosed, please indicate all types.
Datatyp
boolean
Alias
- UMLS CUI [1]
- C0026764
Beskrivning
If several NHLs have been diagnosed, please indicate all types.
Datatyp
boolean
Alias
- UMLS CUI [1]
- C0023434
Beskrivning
If several NHLs have been diagnosed, please indicate all types.
Datatyp
boolean
Alias
- UMLS CUI [1,1]
- C1334170
- UMLS CUI [1,2]
- C0205394
Beskrivning
If several NHLs have been diagnosed, please indicate all types.
Datatyp
boolean
Alias
- UMLS CUI [1,1]
- C0439673
- UMLS CUI [1,2]
- C0024305
Beskrivning
If several NHLs have been diagnosed, please indicate all types.
Datatyp
boolean
Alias
- UMLS CUI [1,1]
- C1298908
- UMLS CUI [1,2]
- C0024305
Beskrivning
Diagnosis date of hematological / oncological disease
Alias
- UMLS CUI-1
- C0018939
- UMLS CUI-2
- C2316983
- UMLS CUI-3
- C0027651
- UMLS CUI-4
- C2316983
Beskrivning
Please indicate how much time has passed since the patient was first diagnosed.
Datatyp
integer
Alias
- UMLS CUI [1,1]
- C0018939
- UMLS CUI [1,2]
- C2316983
- UMLS CUI [2,1]
- C0027651
- UMLS CUI [2,2]
- C2316983
Beskrivning
Status at Baseline
Alias
- UMLS CUI-1
- C0699749
- UMLS CUI-2
- C1175175
- UMLS CUI-3
- C1511790
Beskrivning
BL (ECOG)
Datatyp
integer
Alias
- UMLS CUI [1,1]
- C1512162
- UMLS CUI [1,2]
- C1442488
Beskrivning
Active disease
Datatyp
integer
Alias
- UMLS CUI [1]
- C2707252
Beskrivning
Chemotherapy
Datatyp
integer
Alias
- UMLS CUI [1]
- C3665472
Beskrivning
High dose steroids
Datatyp
integer
Alias
- UMLS CUI [1,1]
- C0038317
- UMLS CUI [1,2]
- C0444956
Beskrivning
Targeted therapy
Datatyp
integer
Alias
- UMLS CUI [1]
- C2985566
Beskrivning
Other immunosuppressive medication
Datatyp
integer
Alias
- UMLS CUI [1,1]
- C0205394
- UMLS CUI [1,2]
- C0021081
Beskrivning
Remission
Datatyp
integer
Alias
- UMLS CUI [1]
- C0544452
Beskrivning
Anti-cancer therapy
Alias
- UMLS CUI-1
- C0920425
Beskrivning
Systemic anti-cancer last month
Datatyp
boolean
Alias
- UMLS CUI [1,1]
- C1515119
- UMLS CUI [1,2]
- C2360065
- UMLS CUI [1,3]
- C4331910
Beskrivning
Indicate the name of the drug/regimen and specify the time frame.
Datatyp
text
Alias
- UMLS CUI [1,1]
- C1515119
- UMLS CUI [1,2]
- C2360065
- UMLS CUI [1,3]
- C4331910
Beskrivning
Systemic anti-cancer last 3 months
Datatyp
boolean
Alias
- UMLS CUI [1,1]
- C1515119
- UMLS CUI [1,2]
- C2360065
- UMLS CUI [1,3]
- C3887294
Beskrivning
Indicate the name of the regimen and specify the time frame.
Datatyp
text
Alias
- UMLS CUI [1,1]
- C1515119
- UMLS CUI [1,2]
- C2360065
- UMLS CUI [1,3]
- C3887294
Beskrivning
Surgery last 3 months
Datatyp
boolean
Alias
- UMLS CUI [1,1]
- C0543467
- UMLS CUI [1,2]
- C3887294
Beskrivning
Radiotherapy last 3 months
Datatyp
boolean
Alias
- UMLS CUI [1,1]
- C1522449
- UMLS CUI [1,2]
- C3887294
Beskrivning
No anti-cancer therapy
Datatyp
boolean
Alias
- UMLS CUI [1,1]
- C0920425
- UMLS CUI [1,2]
- C0549184
Beskrivning
Unknown anti-cancer therapy
Datatyp
boolean
Alias
- UMLS CUI [1,1]
- C0439673
- UMLS CUI [1,2]
- C0920425
Beskrivning
Stem cell transplantation
Alias
- UMLS CUI-1
- C1504389
Beskrivning
Allogenic SCT
Datatyp
boolean
Alias
- UMLS CUI [1]
- C2242529
Beskrivning
Please provide the number of months that have passed since the stem cell transplantation.
Datatyp
text
Måttenheter
- months
Alias
- UMLS CUI [1,1]
- C2242529
- UMLS CUI [1,2]
- C1272706
Beskrivning
Autologous SCT
Datatyp
boolean
Alias
- UMLS CUI [1]
- C1831743
Beskrivning
Please provide the number of months that have passed since the stem cell transplantation.
Datatyp
text
Måttenheter
- months
Alias
- UMLS CUI [1,1]
- C1831743
- UMLS CUI [1,2]
- C1272706
Beskrivning
Unknown SCT
Datatyp
boolean
Alias
- UMLS CUI [1,1]
- C1504389
- UMLS CUI [1,2]
- C0439673
Beskrivning
Specific hypogammaglobuliaemia: IgG
Alias
- UMLS CUI-1
- C0086438
- UMLS CUI-2
- C0020852
Beskrivning
Is data entry for this section finished?
Alias
- UMLS CUI-1
- C4684556
- UMLS CUI-2
- C1828479
- UMLS CUI-3
- C0205197
Similar models
Oncological Sub-cohort
- StudyEvent: Baseline
- StudyEvent: Comorbidities and Pre-medication
- StudyEvent: Phases
- StudyEvent: Therapeutics
- StudyEvent: Diagnostics
C0018939 (UMLS CUI-2)
C0205183 (UMLS CUI [1,2])
C0376545 (UMLS CUI [1,2])
C0032463 (UMLS CUI [2])
C0040028 (UMLS CUI [3])
C0280100 (UMLS CUI-2)
C0205394 (UMLS CUI-3)
C0018417 (UMLS CUI [1,2])
C0205394 (UMLS CUI-2)
C0277554 (UMLS CUI [1,2])
C0277554 (UMLS CUI [1,2])
C1521902 (UMLS CUI [1,3])
C0277554 (UMLS CUI [1,2])
C0024305 (UMLS CUI-2)
C1521902 (UMLS CUI-3)
C0205394 (UMLS CUI [1,2])
C0024305 (UMLS CUI [1,2])
C0024305 (UMLS CUI [1,2])
C2316983 (UMLS CUI-2)
C0027651 (UMLS CUI-3)
C2316983 (UMLS CUI-4)
C2316983 (UMLS CUI [1,2])
C0027651 (UMLS CUI [2,1])
C2316983 (UMLS CUI [2,2])
C1175175 (UMLS CUI-2)
C1511790 (UMLS CUI-3)
C1442488 (UMLS CUI [1,2])
C0444956 (UMLS CUI [1,2])
C0021081 (UMLS CUI [1,2])
C2360065 (UMLS CUI [1,2])
C4331910 (UMLS CUI [1,3])
C2360065 (UMLS CUI [1,2])
C4331910 (UMLS CUI [1,3])
C2360065 (UMLS CUI [1,2])
C3887294 (UMLS CUI [1,3])
C2360065 (UMLS CUI [1,2])
C3887294 (UMLS CUI [1,3])
C3887294 (UMLS CUI [1,2])
C3887294 (UMLS CUI [1,2])
C0549184 (UMLS CUI [1,2])
C0920425 (UMLS CUI [1,2])
C1272706 (UMLS CUI [1,2])
C1272706 (UMLS CUI [1,2])
C0439673 (UMLS CUI [1,2])
C0020852 (UMLS CUI-2)
C0020852 (UMLS CUI [1,2])
C1828479 (UMLS CUI-2)
C0205197 (UMLS CUI-3)
C1828479 (UMLS CUI [1,2])
C0205197 (UMLS CUI [1,3])