ID
42476
Descrição
Study Title: LEOSS: Lean European Open Survey on SARS-CoV-2 Infected Patients https://leoss.net Study Indication: COVID-19 Date: 19.03.2021 Published with permission by Prof. Dr. med. J.-J. Vehreschild. LEOSS, a multi-center cohort study, has been created to get more in-depth knowledge about the epidemiology and clinical course of patients infected with SARS-CoV-2. Initiated by the ESCMID Emerging Infections Task Force (EITaF) and the German Infectious Disease Society, and supported by all German Centers for Health Research (DZG), LEOSS has developed into an international network of contributors. Via an integrative research approach with anonymous recruitment and collection of routine data in an open science context, LEOSS is building a uniform clinical dataset and providing real-time analyses. For more information feel free to explore https://leoss.net/. Please note that only cases with known outcome are collected! Baseline / diagnosis is defined as the day the sample of the first positive SARS-CoV-2 result was taken. Criteria of the Uncomplicated Phase: Asymptomatic OR Symptoms of upper respiratory tract infection and/or Nausea, emesis, diarrhea and/or Fever Remember: The Uncomplicated Phase ends, if a previously febrile patient has no fever anymore and has completed 14 days of follow-up without entering Complicated or Critical Phase; then move to Recovery Phase. Also, as soon as one of the criteria of the Complicated or Critical Phase are fulfilled, Uncomplicated Phase ends; move over to there. If the patient has died, the phase ends with the death of the patient. If the patient has died, do not report terminal values, e.g. those recorded after switching off life-support or heart rate "0" after death of the patient. Criteria of the Complicated Phase: * Need for oxygen supplementation (In patients with prior oxygen home therapy, clinically meaningful increase in need for oxygenation.) * paO2 at room air < 70 mmHg * SO2 at room air < 90 % * GOT or GPT > 5x ULN * New cardiac arrhythmia * New pericardial effusion >1cm * New heart failure with pulmonary edema, congestive hepatopathy or peripheral edema Remember: The Complicated Phase ends, if none of the criteria for the Complicated Phase is fulfilled anymore AND the patient is free of fever; then move to Recovery Phase. Also, as soon as one of the criteria of the Critical Phase are fulfilled, Complicated Phase ends; move over to Critical Phase. If the patient has died, the phase ends with the death of the patient. If the patient has died, do not report terminal values, e.g. those recorded after switching off life-support or heart rate "0" after death of the patient. Criteria of the Critical Phase: * Need for catecholamines * Life-threatening cardiac arrhythmia * Mechanical ventilation (invasive or non-invasive) * Liver failure with Quick< 50% * qSOFA >= 2 * Renal failure in need of dialysis Remember: The Critical Phase ends as soon as none of the criteria for the Critical Phase is fulfilled anymore AND the patient is free of fever. If the patient has died, it ends with the death of the patient. If the patient has died, do not report terminal values, i.e. those recorded after turning off life-support or heart rate "0" after death of the patient. Criteria of the Recovery Phase: *Improvement by at least one phase, i.e. Critical to Complicated or Complicated to Uncomplicated * Defervescence Remember: Uncomplicated asymptomatic patients enter recovery phase after 14 days of observation without disease progression No further progression or re-hospitalization If a text field can't be filled out, note 'ND' (for not determined).
Link
Palavras-chave
Versões (3)
- 02/07/2021 02/07/2021 - Sarah Riepenhausen
- 15/07/2021 15/07/2021 - Sarah Riepenhausen
- 16/07/2021 16/07/2021 - Sarah Riepenhausen
Titular dos direitos
LEOSS
Transferido a
16 de julho de 2021
DOI
10.21961/mdm:42476
Licença
Creative Commons BY 4.0
Comentários do modelo :
Aqui pode comentar o modelo. Pode comentá-lo especificamente através dos balões de texto nos grupos de itens e itens.
Comentários do grupo de itens para :
Comentários do item para :
Para descarregar formulários, precisa de ter uma sessão iniciada. Por favor faça login ou registe-se gratuitamente.
LEOSS: Lean European Open Survey on SARS-CoV-2 Infected Patients
Oncological Sub-cohort
- StudyEvent: Baseline
- StudyEvent: Comorbidities and Pre-medication
- StudyEvent: Phases
- StudyEvent: Therapeutics
- StudyEvent: Diagnostics
Descrição
Underlying disease: Solid tumors
Alias
- UMLS CUI-1
- C0277554
- UMLS CUI-2
- C0280100
- UMLS CUI-3
- C0205394
Descrição
Gastrointestinal cancer
Tipo de dados
boolean
Alias
- UMLS CUI [1]
- C0685938
Descrição
Lung cancer
Tipo de dados
boolean
Alias
- UMLS CUI [1]
- C0242379
Descrição
Head/Neck cancer
Tipo de dados
boolean
Alias
- UMLS CUI [1]
- C0278996
Descrição
Prostate cancer
Tipo de dados
boolean
Alias
- UMLS CUI [1]
- C0600139
Descrição
Bladder cancer
Tipo de dados
boolean
Alias
- UMLS CUI [1]
- C0005684
Descrição
Breast cancer
Tipo de dados
boolean
Alias
- UMLS CUI [1]
- C0678222
Descrição
Other gynecological cancer
Tipo de dados
boolean
Alias
- UMLS CUI [1,1]
- C1707251
- UMLS CUI [1,2]
- C0018417
Descrição
Malignant melanoma
Tipo de dados
boolean
Alias
- UMLS CUI [1]
- C0025202
Descrição
Underlying disease: Other underlying diseases
Alias
- UMLS CUI-1
- C0277554
- UMLS CUI-2
- C0205394
Descrição
Other underlying diseases
Tipo de dados
boolean
Alias
- UMLS CUI [1,1]
- C0205394
- UMLS CUI [1,2]
- C0277554
Descrição
Other underlying diseases_text
Tipo de dados
text
Alias
- UMLS CUI [1,1]
- C0205394
- UMLS CUI [1,2]
- C0277554
- UMLS CUI [1,3]
- C1521902
Descrição
Unknown underlying diseases
Tipo de dados
boolean
Alias
- UMLS CUI [1,1]
- C0439673
- UMLS CUI [1,2]
- C0277554
Descrição
Please specify the underlying NHL
Alias
- UMLS CUI-1
- C0277554
- UMLS CUI-2
- C0024305
- UMLS CUI-3
- C1521902
Descrição
If several NHLs have been diagnosed, please indicate all types.
Tipo de dados
boolean
Alias
- UMLS CUI [1]
- C1332225
Descrição
If several NHLs have been diagnosed, please indicate all types.
Tipo de dados
boolean
Alias
- UMLS CUI [1]
- C0026764
Descrição
If several NHLs have been diagnosed, please indicate all types.
Tipo de dados
boolean
Alias
- UMLS CUI [1]
- C0023434
Descrição
If several NHLs have been diagnosed, please indicate all types.
Tipo de dados
boolean
Alias
- UMLS CUI [1,1]
- C1334170
- UMLS CUI [1,2]
- C0205394
Descrição
If several NHLs have been diagnosed, please indicate all types.
Tipo de dados
boolean
Alias
- UMLS CUI [1,1]
- C0439673
- UMLS CUI [1,2]
- C0024305
Descrição
If several NHLs have been diagnosed, please indicate all types.
Tipo de dados
boolean
Alias
- UMLS CUI [1,1]
- C1298908
- UMLS CUI [1,2]
- C0024305
Descrição
Diagnosis date of hematological / oncological disease
Alias
- UMLS CUI-1
- C0018939
- UMLS CUI-2
- C2316983
- UMLS CUI-3
- C0027651
- UMLS CUI-4
- C2316983
Descrição
Please indicate how much time has passed since the patient was first diagnosed.
Tipo de dados
integer
Alias
- UMLS CUI [1,1]
- C0018939
- UMLS CUI [1,2]
- C2316983
- UMLS CUI [2,1]
- C0027651
- UMLS CUI [2,2]
- C2316983
Descrição
Status at Baseline
Alias
- UMLS CUI-1
- C0699749
- UMLS CUI-2
- C1175175
- UMLS CUI-3
- C1511790
Descrição
BL (ECOG)
Tipo de dados
integer
Alias
- UMLS CUI [1,1]
- C1512162
- UMLS CUI [1,2]
- C1442488
Descrição
Active disease
Tipo de dados
integer
Alias
- UMLS CUI [1]
- C2707252
Descrição
Chemotherapy
Tipo de dados
integer
Alias
- UMLS CUI [1]
- C3665472
Descrição
High dose steroids
Tipo de dados
integer
Alias
- UMLS CUI [1,1]
- C0038317
- UMLS CUI [1,2]
- C0444956
Descrição
Targeted therapy
Tipo de dados
integer
Alias
- UMLS CUI [1]
- C2985566
Descrição
Other immunosuppressive medication
Tipo de dados
integer
Alias
- UMLS CUI [1,1]
- C0205394
- UMLS CUI [1,2]
- C0021081
Descrição
Remission
Tipo de dados
integer
Alias
- UMLS CUI [1]
- C0544452
Descrição
Anti-cancer therapy
Alias
- UMLS CUI-1
- C0920425
Descrição
Systemic anti-cancer last month
Tipo de dados
boolean
Alias
- UMLS CUI [1,1]
- C1515119
- UMLS CUI [1,2]
- C2360065
- UMLS CUI [1,3]
- C4331910
Descrição
Indicate the name of the drug/regimen and specify the time frame.
Tipo de dados
text
Alias
- UMLS CUI [1,1]
- C1515119
- UMLS CUI [1,2]
- C2360065
- UMLS CUI [1,3]
- C4331910
Descrição
Systemic anti-cancer last 3 months
Tipo de dados
boolean
Alias
- UMLS CUI [1,1]
- C1515119
- UMLS CUI [1,2]
- C2360065
- UMLS CUI [1,3]
- C3887294
Descrição
Indicate the name of the regimen and specify the time frame.
Tipo de dados
text
Alias
- UMLS CUI [1,1]
- C1515119
- UMLS CUI [1,2]
- C2360065
- UMLS CUI [1,3]
- C3887294
Descrição
Surgery last 3 months
Tipo de dados
boolean
Alias
- UMLS CUI [1,1]
- C0543467
- UMLS CUI [1,2]
- C3887294
Descrição
Radiotherapy last 3 months
Tipo de dados
boolean
Alias
- UMLS CUI [1,1]
- C1522449
- UMLS CUI [1,2]
- C3887294
Descrição
No anti-cancer therapy
Tipo de dados
boolean
Alias
- UMLS CUI [1,1]
- C0920425
- UMLS CUI [1,2]
- C0549184
Descrição
Unknown anti-cancer therapy
Tipo de dados
boolean
Alias
- UMLS CUI [1,1]
- C0439673
- UMLS CUI [1,2]
- C0920425
Descrição
Stem cell transplantation
Alias
- UMLS CUI-1
- C1504389
Descrição
Allogenic SCT
Tipo de dados
boolean
Alias
- UMLS CUI [1]
- C2242529
Descrição
Please provide the number of months that have passed since the stem cell transplantation.
Tipo de dados
text
Unidades de medida
- months
Alias
- UMLS CUI [1,1]
- C2242529
- UMLS CUI [1,2]
- C1272706
Descrição
Autologous SCT
Tipo de dados
boolean
Alias
- UMLS CUI [1]
- C1831743
Descrição
Please provide the number of months that have passed since the stem cell transplantation.
Tipo de dados
text
Unidades de medida
- months
Alias
- UMLS CUI [1,1]
- C1831743
- UMLS CUI [1,2]
- C1272706
Descrição
Unknown SCT
Tipo de dados
boolean
Alias
- UMLS CUI [1,1]
- C1504389
- UMLS CUI [1,2]
- C0439673
Descrição
Specific hypogammaglobuliaemia: IgG
Alias
- UMLS CUI-1
- C0086438
- UMLS CUI-2
- C0020852
Descrição
Is data entry for this section finished?
Alias
- UMLS CUI-1
- C4684556
- UMLS CUI-2
- C1828479
- UMLS CUI-3
- C0205197
Similar models
Oncological Sub-cohort
- StudyEvent: Baseline
- StudyEvent: Comorbidities and Pre-medication
- StudyEvent: Phases
- StudyEvent: Therapeutics
- StudyEvent: Diagnostics
C0018939 (UMLS CUI-2)
C0205183 (UMLS CUI [1,2])
C0376545 (UMLS CUI [1,2])
C0032463 (UMLS CUI [2])
C0040028 (UMLS CUI [3])
C0280100 (UMLS CUI-2)
C0205394 (UMLS CUI-3)
C0018417 (UMLS CUI [1,2])
C0205394 (UMLS CUI-2)
C0277554 (UMLS CUI [1,2])
C0277554 (UMLS CUI [1,2])
C1521902 (UMLS CUI [1,3])
C0277554 (UMLS CUI [1,2])
C0024305 (UMLS CUI-2)
C1521902 (UMLS CUI-3)
C0205394 (UMLS CUI [1,2])
C0024305 (UMLS CUI [1,2])
C0024305 (UMLS CUI [1,2])
C2316983 (UMLS CUI-2)
C0027651 (UMLS CUI-3)
C2316983 (UMLS CUI-4)
C2316983 (UMLS CUI [1,2])
C0027651 (UMLS CUI [2,1])
C2316983 (UMLS CUI [2,2])
C1175175 (UMLS CUI-2)
C1511790 (UMLS CUI-3)
C1442488 (UMLS CUI [1,2])
C0444956 (UMLS CUI [1,2])
C0021081 (UMLS CUI [1,2])
C2360065 (UMLS CUI [1,2])
C4331910 (UMLS CUI [1,3])
C2360065 (UMLS CUI [1,2])
C4331910 (UMLS CUI [1,3])
C2360065 (UMLS CUI [1,2])
C3887294 (UMLS CUI [1,3])
C2360065 (UMLS CUI [1,2])
C3887294 (UMLS CUI [1,3])
C3887294 (UMLS CUI [1,2])
C3887294 (UMLS CUI [1,2])
C0549184 (UMLS CUI [1,2])
C0920425 (UMLS CUI [1,2])
C1272706 (UMLS CUI [1,2])
C1272706 (UMLS CUI [1,2])
C0439673 (UMLS CUI [1,2])
C0020852 (UMLS CUI-2)
C0020852 (UMLS CUI [1,2])
C1828479 (UMLS CUI-2)
C0205197 (UMLS CUI-3)
C1828479 (UMLS CUI [1,2])
C0205197 (UMLS CUI [1,3])