ID
42476
Descrizione
Study Title: LEOSS: Lean European Open Survey on SARS-CoV-2 Infected Patients https://leoss.net Study Indication: COVID-19 Date: 19.03.2021 Published with permission by Prof. Dr. med. J.-J. Vehreschild. LEOSS, a multi-center cohort study, has been created to get more in-depth knowledge about the epidemiology and clinical course of patients infected with SARS-CoV-2. Initiated by the ESCMID Emerging Infections Task Force (EITaF) and the German Infectious Disease Society, and supported by all German Centers for Health Research (DZG), LEOSS has developed into an international network of contributors. Via an integrative research approach with anonymous recruitment and collection of routine data in an open science context, LEOSS is building a uniform clinical dataset and providing real-time analyses. For more information feel free to explore https://leoss.net/. Please note that only cases with known outcome are collected! Baseline / diagnosis is defined as the day the sample of the first positive SARS-CoV-2 result was taken. Criteria of the Uncomplicated Phase: Asymptomatic OR Symptoms of upper respiratory tract infection and/or Nausea, emesis, diarrhea and/or Fever Remember: The Uncomplicated Phase ends, if a previously febrile patient has no fever anymore and has completed 14 days of follow-up without entering Complicated or Critical Phase; then move to Recovery Phase. Also, as soon as one of the criteria of the Complicated or Critical Phase are fulfilled, Uncomplicated Phase ends; move over to there. If the patient has died, the phase ends with the death of the patient. If the patient has died, do not report terminal values, e.g. those recorded after switching off life-support or heart rate "0" after death of the patient. Criteria of the Complicated Phase: * Need for oxygen supplementation (In patients with prior oxygen home therapy, clinically meaningful increase in need for oxygenation.) * paO2 at room air < 70 mmHg * SO2 at room air < 90 % * GOT or GPT > 5x ULN * New cardiac arrhythmia * New pericardial effusion >1cm * New heart failure with pulmonary edema, congestive hepatopathy or peripheral edema Remember: The Complicated Phase ends, if none of the criteria for the Complicated Phase is fulfilled anymore AND the patient is free of fever; then move to Recovery Phase. Also, as soon as one of the criteria of the Critical Phase are fulfilled, Complicated Phase ends; move over to Critical Phase. If the patient has died, the phase ends with the death of the patient. If the patient has died, do not report terminal values, e.g. those recorded after switching off life-support or heart rate "0" after death of the patient. Criteria of the Critical Phase: * Need for catecholamines * Life-threatening cardiac arrhythmia * Mechanical ventilation (invasive or non-invasive) * Liver failure with Quick< 50% * qSOFA >= 2 * Renal failure in need of dialysis Remember: The Critical Phase ends as soon as none of the criteria for the Critical Phase is fulfilled anymore AND the patient is free of fever. If the patient has died, it ends with the death of the patient. If the patient has died, do not report terminal values, i.e. those recorded after turning off life-support or heart rate "0" after death of the patient. Criteria of the Recovery Phase: *Improvement by at least one phase, i.e. Critical to Complicated or Complicated to Uncomplicated * Defervescence Remember: Uncomplicated asymptomatic patients enter recovery phase after 14 days of observation without disease progression No further progression or re-hospitalization If a text field can't be filled out, note 'ND' (for not determined).
collegamento
Keywords
versioni (3)
- 02/07/21 02/07/21 - Sarah Riepenhausen
- 15/07/21 15/07/21 - Sarah Riepenhausen
- 16/07/21 16/07/21 - Sarah Riepenhausen
Titolare del copyright
LEOSS
Caricato su
16 luglio 2021
DOI
10.21961/mdm:42476
Licenza
Creative Commons BY 4.0
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LEOSS: Lean European Open Survey on SARS-CoV-2 Infected Patients
Oncological Sub-cohort
- StudyEvent: Baseline
- StudyEvent: Comorbidities and Pre-medication
- StudyEvent: Phases
- StudyEvent: Therapeutics
- StudyEvent: Diagnostics
Descrizione
Underlying disease: Solid tumors
Alias
- UMLS CUI-1
- C0277554
- UMLS CUI-2
- C0280100
- UMLS CUI-3
- C0205394
Descrizione
Gastrointestinal cancer
Tipo di dati
boolean
Alias
- UMLS CUI [1]
- C0685938
Descrizione
Lung cancer
Tipo di dati
boolean
Alias
- UMLS CUI [1]
- C0242379
Descrizione
Head/Neck cancer
Tipo di dati
boolean
Alias
- UMLS CUI [1]
- C0278996
Descrizione
Prostate cancer
Tipo di dati
boolean
Alias
- UMLS CUI [1]
- C0600139
Descrizione
Bladder cancer
Tipo di dati
boolean
Alias
- UMLS CUI [1]
- C0005684
Descrizione
Breast cancer
Tipo di dati
boolean
Alias
- UMLS CUI [1]
- C0678222
Descrizione
Other gynecological cancer
Tipo di dati
boolean
Alias
- UMLS CUI [1,1]
- C1707251
- UMLS CUI [1,2]
- C0018417
Descrizione
Malignant melanoma
Tipo di dati
boolean
Alias
- UMLS CUI [1]
- C0025202
Descrizione
Underlying disease: Other underlying diseases
Alias
- UMLS CUI-1
- C0277554
- UMLS CUI-2
- C0205394
Descrizione
Other underlying diseases
Tipo di dati
boolean
Alias
- UMLS CUI [1,1]
- C0205394
- UMLS CUI [1,2]
- C0277554
Descrizione
Other underlying diseases_text
Tipo di dati
text
Alias
- UMLS CUI [1,1]
- C0205394
- UMLS CUI [1,2]
- C0277554
- UMLS CUI [1,3]
- C1521902
Descrizione
Unknown underlying diseases
Tipo di dati
boolean
Alias
- UMLS CUI [1,1]
- C0439673
- UMLS CUI [1,2]
- C0277554
Descrizione
Please specify the underlying NHL
Alias
- UMLS CUI-1
- C0277554
- UMLS CUI-2
- C0024305
- UMLS CUI-3
- C1521902
Descrizione
If several NHLs have been diagnosed, please indicate all types.
Tipo di dati
boolean
Alias
- UMLS CUI [1]
- C1332225
Descrizione
If several NHLs have been diagnosed, please indicate all types.
Tipo di dati
boolean
Alias
- UMLS CUI [1]
- C0026764
Descrizione
If several NHLs have been diagnosed, please indicate all types.
Tipo di dati
boolean
Alias
- UMLS CUI [1]
- C0023434
Descrizione
If several NHLs have been diagnosed, please indicate all types.
Tipo di dati
boolean
Alias
- UMLS CUI [1,1]
- C1334170
- UMLS CUI [1,2]
- C0205394
Descrizione
If several NHLs have been diagnosed, please indicate all types.
Tipo di dati
boolean
Alias
- UMLS CUI [1,1]
- C0439673
- UMLS CUI [1,2]
- C0024305
Descrizione
If several NHLs have been diagnosed, please indicate all types.
Tipo di dati
boolean
Alias
- UMLS CUI [1,1]
- C1298908
- UMLS CUI [1,2]
- C0024305
Descrizione
Diagnosis date of hematological / oncological disease
Alias
- UMLS CUI-1
- C0018939
- UMLS CUI-2
- C2316983
- UMLS CUI-3
- C0027651
- UMLS CUI-4
- C2316983
Descrizione
Please indicate how much time has passed since the patient was first diagnosed.
Tipo di dati
integer
Alias
- UMLS CUI [1,1]
- C0018939
- UMLS CUI [1,2]
- C2316983
- UMLS CUI [2,1]
- C0027651
- UMLS CUI [2,2]
- C2316983
Descrizione
Status at Baseline
Alias
- UMLS CUI-1
- C0699749
- UMLS CUI-2
- C1175175
- UMLS CUI-3
- C1511790
Descrizione
BL (ECOG)
Tipo di dati
integer
Alias
- UMLS CUI [1,1]
- C1512162
- UMLS CUI [1,2]
- C1442488
Descrizione
Active disease
Tipo di dati
integer
Alias
- UMLS CUI [1]
- C2707252
Descrizione
Chemotherapy
Tipo di dati
integer
Alias
- UMLS CUI [1]
- C3665472
Descrizione
High dose steroids
Tipo di dati
integer
Alias
- UMLS CUI [1,1]
- C0038317
- UMLS CUI [1,2]
- C0444956
Descrizione
Targeted therapy
Tipo di dati
integer
Alias
- UMLS CUI [1]
- C2985566
Descrizione
Other immunosuppressive medication
Tipo di dati
integer
Alias
- UMLS CUI [1,1]
- C0205394
- UMLS CUI [1,2]
- C0021081
Descrizione
Remission
Tipo di dati
integer
Alias
- UMLS CUI [1]
- C0544452
Descrizione
Anti-cancer therapy
Alias
- UMLS CUI-1
- C0920425
Descrizione
Systemic anti-cancer last month
Tipo di dati
boolean
Alias
- UMLS CUI [1,1]
- C1515119
- UMLS CUI [1,2]
- C2360065
- UMLS CUI [1,3]
- C4331910
Descrizione
Indicate the name of the drug/regimen and specify the time frame.
Tipo di dati
text
Alias
- UMLS CUI [1,1]
- C1515119
- UMLS CUI [1,2]
- C2360065
- UMLS CUI [1,3]
- C4331910
Descrizione
Systemic anti-cancer last 3 months
Tipo di dati
boolean
Alias
- UMLS CUI [1,1]
- C1515119
- UMLS CUI [1,2]
- C2360065
- UMLS CUI [1,3]
- C3887294
Descrizione
Indicate the name of the regimen and specify the time frame.
Tipo di dati
text
Alias
- UMLS CUI [1,1]
- C1515119
- UMLS CUI [1,2]
- C2360065
- UMLS CUI [1,3]
- C3887294
Descrizione
Surgery last 3 months
Tipo di dati
boolean
Alias
- UMLS CUI [1,1]
- C0543467
- UMLS CUI [1,2]
- C3887294
Descrizione
Radiotherapy last 3 months
Tipo di dati
boolean
Alias
- UMLS CUI [1,1]
- C1522449
- UMLS CUI [1,2]
- C3887294
Descrizione
No anti-cancer therapy
Tipo di dati
boolean
Alias
- UMLS CUI [1,1]
- C0920425
- UMLS CUI [1,2]
- C0549184
Descrizione
Unknown anti-cancer therapy
Tipo di dati
boolean
Alias
- UMLS CUI [1,1]
- C0439673
- UMLS CUI [1,2]
- C0920425
Descrizione
Stem cell transplantation
Alias
- UMLS CUI-1
- C1504389
Descrizione
Allogenic SCT
Tipo di dati
boolean
Alias
- UMLS CUI [1]
- C2242529
Descrizione
Please provide the number of months that have passed since the stem cell transplantation.
Tipo di dati
text
Unità di misura
- months
Alias
- UMLS CUI [1,1]
- C2242529
- UMLS CUI [1,2]
- C1272706
Descrizione
Autologous SCT
Tipo di dati
boolean
Alias
- UMLS CUI [1]
- C1831743
Descrizione
Please provide the number of months that have passed since the stem cell transplantation.
Tipo di dati
text
Unità di misura
- months
Alias
- UMLS CUI [1,1]
- C1831743
- UMLS CUI [1,2]
- C1272706
Descrizione
Unknown SCT
Tipo di dati
boolean
Alias
- UMLS CUI [1,1]
- C1504389
- UMLS CUI [1,2]
- C0439673
Descrizione
Specific hypogammaglobuliaemia: IgG
Alias
- UMLS CUI-1
- C0086438
- UMLS CUI-2
- C0020852
Descrizione
Is data entry for this section finished?
Alias
- UMLS CUI-1
- C4684556
- UMLS CUI-2
- C1828479
- UMLS CUI-3
- C0205197
Similar models
Oncological Sub-cohort
- StudyEvent: Baseline
- StudyEvent: Comorbidities and Pre-medication
- StudyEvent: Phases
- StudyEvent: Therapeutics
- StudyEvent: Diagnostics
C0018939 (UMLS CUI-2)
C0205183 (UMLS CUI [1,2])
C0376545 (UMLS CUI [1,2])
C0032463 (UMLS CUI [2])
C0040028 (UMLS CUI [3])
C0280100 (UMLS CUI-2)
C0205394 (UMLS CUI-3)
C0018417 (UMLS CUI [1,2])
C0205394 (UMLS CUI-2)
C0277554 (UMLS CUI [1,2])
C0277554 (UMLS CUI [1,2])
C1521902 (UMLS CUI [1,3])
C0277554 (UMLS CUI [1,2])
C0024305 (UMLS CUI-2)
C1521902 (UMLS CUI-3)
C0205394 (UMLS CUI [1,2])
C0024305 (UMLS CUI [1,2])
C0024305 (UMLS CUI [1,2])
C2316983 (UMLS CUI-2)
C0027651 (UMLS CUI-3)
C2316983 (UMLS CUI-4)
C2316983 (UMLS CUI [1,2])
C0027651 (UMLS CUI [2,1])
C2316983 (UMLS CUI [2,2])
C1175175 (UMLS CUI-2)
C1511790 (UMLS CUI-3)
C1442488 (UMLS CUI [1,2])
C0444956 (UMLS CUI [1,2])
C0021081 (UMLS CUI [1,2])
C2360065 (UMLS CUI [1,2])
C4331910 (UMLS CUI [1,3])
C2360065 (UMLS CUI [1,2])
C4331910 (UMLS CUI [1,3])
C2360065 (UMLS CUI [1,2])
C3887294 (UMLS CUI [1,3])
C2360065 (UMLS CUI [1,2])
C3887294 (UMLS CUI [1,3])
C3887294 (UMLS CUI [1,2])
C3887294 (UMLS CUI [1,2])
C0549184 (UMLS CUI [1,2])
C0920425 (UMLS CUI [1,2])
C1272706 (UMLS CUI [1,2])
C1272706 (UMLS CUI [1,2])
C0439673 (UMLS CUI [1,2])
C0020852 (UMLS CUI-2)
C0020852 (UMLS CUI [1,2])
C1828479 (UMLS CUI-2)
C0205197 (UMLS CUI-3)
C1828479 (UMLS CUI [1,2])
C0205197 (UMLS CUI [1,3])