ID

42476

Description

Study Title: LEOSS: Lean European Open Survey on SARS-CoV-2 Infected Patients https://leoss.net Study Indication: COVID-19 Date: 19.03.2021 Published with permission by Prof. Dr. med. J.-J. Vehreschild. LEOSS, a multi-center cohort study, has been created to get more in-depth knowledge about the epidemiology and clinical course of patients infected with SARS-CoV-2. Initiated by the ESCMID Emerging Infections Task Force (EITaF) and the German Infectious Disease Society, and supported by all German Centers for Health Research (DZG), LEOSS has developed into an international network of contributors. Via an integrative research approach with anonymous recruitment and collection of routine data in an open science context, LEOSS is building a uniform clinical dataset and providing real-time analyses. For more information feel free to explore https://leoss.net/. Please note that only cases with known outcome are collected! Baseline / diagnosis is defined as the day the sample of the first positive SARS-CoV-2 result was taken. Criteria of the Uncomplicated Phase: Asymptomatic OR Symptoms of upper respiratory tract infection and/or Nausea, emesis, diarrhea and/or Fever Remember: The Uncomplicated Phase ends, if a previously febrile patient has no fever anymore and has completed 14 days of follow-up without entering Complicated or Critical Phase; then move to Recovery Phase. Also, as soon as one of the criteria of the Complicated or Critical Phase are fulfilled, Uncomplicated Phase ends; move over to there. If the patient has died, the phase ends with the death of the patient. If the patient has died, do not report terminal values, e.g. those recorded after switching off life-support or heart rate "0" after death of the patient. Criteria of the Complicated Phase: * Need for oxygen supplementation (In patients with prior oxygen home therapy, clinically meaningful increase in need for oxygenation.) * paO2 at room air < 70 mmHg * SO2 at room air < 90 % * GOT or GPT > 5x ULN * New cardiac arrhythmia * New pericardial effusion >1cm * New heart failure with pulmonary edema, congestive hepatopathy or peripheral edema Remember: The Complicated Phase ends, if none of the criteria for the Complicated Phase is fulfilled anymore AND the patient is free of fever; then move to Recovery Phase. Also, as soon as one of the criteria of the Critical Phase are fulfilled, Complicated Phase ends; move over to Critical Phase. If the patient has died, the phase ends with the death of the patient. If the patient has died, do not report terminal values, e.g. those recorded after switching off life-support or heart rate "0" after death of the patient. Criteria of the Critical Phase: * Need for catecholamines * Life-threatening cardiac arrhythmia * Mechanical ventilation (invasive or non-invasive) * Liver failure with Quick< 50% * qSOFA >= 2 * Renal failure in need of dialysis Remember: The Critical Phase ends as soon as none of the criteria for the Critical Phase is fulfilled anymore AND the patient is free of fever. If the patient has died, it ends with the death of the patient. If the patient has died, do not report terminal values, i.e. those recorded after turning off life-support or heart rate "0" after death of the patient. Criteria of the Recovery Phase: *Improvement by at least one phase, i.e. Critical to Complicated or Complicated to Uncomplicated * Defervescence Remember: Uncomplicated asymptomatic patients enter recovery phase after 14 days of observation without disease progression No further progression or re-hospitalization If a text field can't be filled out, note 'ND' (for not determined).

Link

https://leoss.net

Keywords

  1. 7/2/21 7/2/21 - Sarah Riepenhausen
  2. 7/15/21 7/15/21 - Sarah Riepenhausen
  3. 7/16/21 7/16/21 - Sarah Riepenhausen
Copyright Holder

LEOSS

Uploaded on

July 16, 2021

DOI

10.21961/mdm:42476

License

Creative Commons BY 4.0

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LEOSS: Lean European Open Survey on SARS-CoV-2 Infected Patients

Baseline I

Sociodemography
Description

Sociodemography

Alias
UMLS CUI-1
C0011298
Age at diagnosis
Description

Age at diagnosis

Data type

integer

Alias
UMLS CUI [1]
C1828181
Gender
Description

Gender

Data type

integer

Alias
UMLS CUI [1]
C0079399
Ethnicity
Description

Ethnicity

Data type

integer

Alias
UMLS CUI [1]
C0015031
Country of residence
Description

ISO Alpha-3 code (e.g. Germany= DEU, Iceland= ISL, Spain= ESP)

Data type

text

Alias
UMLS CUI [1]
C1562954
ZIP code area
Description

Please enter the first 3-digits of the zip code of the place of residence

Data type

text

Alias
UMLS CUI [1,1]
C1514254
UMLS CUI [1,2]
C0682130
Indicate if the patient is involved in the health care sector
Description

Involvement in health care sector

Data type

integer

Alias
UMLS CUI [1,1]
C1314939
UMLS CUI [1,2]
C0086388
Indicate other involvement
Description

Other involvement

Data type

text

Alias
UMLS CUI [1,1]
C1314939
UMLS CUI [1,2]
C0205394
Where did the patient stay before SARS-CoV-2 detection?
Description

Patients location before SARS-CoV-2 detection

Data type

integer

Alias
UMLS CUI [1,1]
C0030705
UMLS CUI [1,2]
C0450429
UMLS CUI [1,3]
C0332152
UMLS CUI [1,4]
C5203676
UMLS CUI [1,5]
C1511790
Indicate other place of stay
Description

Other location before SARS-CoV-2 detection

Data type

text

Alias
UMLS CUI [1,1]
C0450429
UMLS CUI [1,2]
C0332152
UMLS CUI [1,3]
C5203676
UMLS CUI [1,4]
C1511790
UMLS CUI [1,5]
C3845569
Where did the patient stay after the follow-up period?
Description

In case of inpatient treatment indicate where was the patient discharged to. In case of outpatient treatment indicate where the patient was staying at the last contact.

Data type

integer

Alias
UMLS CUI [1,1]
C0030705
UMLS CUI [1,2]
C0450429
UMLS CUI [1,3]
C0687676
UMLS CUI [1,4]
C1522577
Indicate other place of stay
Description

Other location after follow-up period

Data type

text

Alias
UMLS CUI [1,1]
C0030705
UMLS CUI [1,2]
C0450429
UMLS CUI [1,3]
C0687676
UMLS CUI [1,4]
C1522577
UMLS CUI [1,5]
C3845569
Comorbidities, Central nervous system / Neurological disesases
Description

Comorbidities, Central nervous system / Neurological disesases

Alias
UMLS CUI-1
C0009488
UMLS CUI-2
C0007682
UMLS CUI-3
C0027765
Hemiplegia
Description

Comorbidities that existed before the positive testing for SARS-CoV-2 Unknown means that there is no access to the patient history

Data type

integer

Alias
UMLS CUI [1]
C0018991
Dementia
Description

Comorbidities that existed before the positive testing for SARS-CoV-2 Unknown means that there is no access to the patient history

Data type

integer

Alias
UMLS CUI [1]
C0497327
Cerebrovascular disease, stroke, TIA
Description

Comorbidities that existed before the positive testing for SARS-CoV-2 Unknown means that there is no access to the patient history

Data type

integer

Alias
UMLS CUI [1]
C0007820
UMLS CUI [2]
C0038454
UMLS CUI [3]
C0007787
Motoneuron disease (e.g. amyotrophic lateral sclerosis, spinal muscular atrophy)
Description

Comorbidities that existed before the positive testing for SARS-CoV-2 Unknown means that there is no access to the patient history

Data type

integer

Alias
UMLS CUI [1,1]
C0026609
UMLS CUI [1,2]
C0012634
UMLS CUI [2]
C0002736
UMLS CUI [3]
C0026847
Movement disorder (e.g. Parkinson's disease, Dystonia, Ataxia, Tremor)
Description

Comorbidities that existed before the positive testing for SARS-CoV-2 Unknown means that there is no access to the patient history

Data type

integer

Alias
UMLS CUI [1]
C0026650
UMLS CUI [2]
C0030567
UMLS CUI [3]
C0013421
UMLS CUI [4]
C0004134
UMLS CUI [5]
C0040822
Multiple sclerosis
Description

Comorbidities that existed before the positive testing for SARS-CoV-2 Unknown means that there is no access to the patient history

Data type

integer

Alias
UMLS CUI [1]
C0026769
Myasthenia gravis
Description

Comorbidities that existed before the positive testing for SARS-CoV-2 Unknown means that there is no access to the patient history

Data type

integer

Alias
UMLS CUI [1]
C0026896
Neuromyelitis optica spectrum disorder (NMOSD)
Description

Comorbidities that existed before the positive testing for SARS-CoV-2 Unknown means that there is no access to the patient history

Data type

integer

Alias
UMLS CUI [1]
C0027873
Other neurological autoimmune diseases
Description

Comorbidities that existed before the positive testing for SARS-CoV-2 Unknown means that there is no access to the patient history

Data type

integer

Alias
UMLS CUI [1,1]
C0004364
UMLS CUI [1,2]
C0027765
UMLS CUI [1,3]
C0205394
Other prior neurological disease
Description

Comorbidities that existed before the positive testing for SARS-CoV-2 Unknown means that there is no access to the patient history

Data type

integer

Alias
UMLS CUI [1,1]
C2015799
UMLS CUI [1,2]
C0332152
UMLS CUI [1,3]
C5203670
Comorbidities, Cardiovascular diseases
Description

Comorbidities, Cardiovascular diseases

Alias
UMLS CUI-1
C0009488
UMLS CUI-2
C0728936
Myocardial infarction
Description

Comorbidities that existed before the positive testing for SARS-CoV-2 Unknown means that there is no access to the patient history

Data type

integer

Alias
UMLS CUI [1]
C0027051
Aortic stenosis
Description

Comorbidities that existed before the positive testing for SARS-CoV-2 Unknown means that there is no access to the patient history

Data type

integer

Alias
UMLS CUI [1]
C0003507
AV block
Description

Comorbidities that existed before the positive testing for SARS-CoV-2 Unknown means that there is no access to the patient history

Data type

integer

Alias
UMLS CUI [1]
C0004245
Carotid arterial disease
Description

Comorbidities that existed before the positive testing for SARS-CoV-2 Unknown means that there is no access to the patient history

Data type

integer

Alias
UMLS CUI [1]
C0007273
Chronic heart failure
Description

Comorbidities that existed before the positive testing for SARS-CoV-2 Unknown means that there is no access to the patient history

Data type

integer

Alias
UMLS CUI [1]
C0264716
Peripheral vascular disease
Description

Comorbidities that existed before the positive testing for SARS-CoV-2 Unknown means that there is no access to the patient history

Data type

integer

Alias
UMLS CUI [1]
C0085096
Hypertension
Description

Comorbidities that existed before the positive testing for SARS-CoV-2 Unknown means that there is no access to the patient history

Data type

integer

Alias
UMLS CUI [1]
C0020538
Atrial fibrillation
Description

Comorbidities that existed before the positive testing for SARS-CoV-2 Unknown means that there is no access to the patient history

Data type

integer

Alias
UMLS CUI [1]
C0004238
Coronary artery disease
Description

Comorbidities that existed before the positive testing for SARS-CoV-2 Unknown means that there is no access to the patient history

Data type

integer

Alias
UMLS CUI [1]
C1956346
Other cardiovascular disease
Description

Comorbidities that existed before the positive testing for SARS-CoV-2 Unknown means that there is no access to the patient history

Data type

integer

Alias
UMLS CUI [1,1]
C0007222
UMLS CUI [1,2]
C0205394
Comorbidities, Pulmonary diseases
Description

Comorbidities, Pulmonary diseases

Alias
UMLS CUI-1
C0009488
UMLS CUI-2
C0024115
COPD
Description

Comorbidities that existed before the positive testing for SARS-CoV-2 Unknown means that there is no access to the patient history

Data type

integer

Alias
UMLS CUI [1]
C0024117
Asthma
Description

Comorbidities that existed before the positive testing for SARS-CoV-2 Unknown means that there is no access to the patient history

Data type

integer

Alias
UMLS CUI [1]
C0004096
Other chronic pulmonary diseases
Description

Comorbidities that existed before the positive testing for SARS-CoV-2 Unknown means that there is no access to the patient history

Data type

integer

Alias
UMLS CUI [1,1]
C0746102
UMLS CUI [1,2]
C0205394
Comorbidities, Hematological / oncological diseases
Description

Comorbidities, Hematological / oncological diseases

Alias
UMLS CUI-1
C0009488
UMLS CUI-2
C0018939
UMLS CUI-3
C0442867
Leukemia
Description

Comorbidities that existed before the positive testing for SARS-CoV-2 Unknown means that there is no access to the patient history

Data type

integer

Alias
UMLS CUI [1]
C0023418
Lymphoma
Description

Comorbidities that existed before the positive testing for SARS-CoV-2 Unknown means that there is no access to the patient history

Data type

integer

Alias
UMLS CUI [1]
C0024299
Solid tumor
Description

Comorbidities that existed before the positive testing for SARS-CoV-2 Unknown means that there is no access to the patient history

Data type

integer

Alias
UMLS CUI [1]
C0280100
Solid tumor, metastasized
Description

Comorbidities that existed before the positive testing for SARS-CoV-2 Unknown means that there is no access to the patient history

Data type

integer

Alias
UMLS CUI [1,1]
C0280100
UMLS CUI [1,2]
C0027627
Stem cell transplantation
Description

Comorbidities that existed before the positive testing for SARS-CoV-2 Unknown means that there is no access to the patient history

Data type

integer

Alias
UMLS CUI [1]
C1504389
Other hematological disease
Description

Comorbidities that existed before the positive testing for SARS-CoV-2 Unknown means that there is no access to the patient history

Data type

integer

Alias
UMLS CUI [1,1]
C0018939
UMLS CUI [1,2]
C0205394
Comorbidities, Rheumatological diseases
Description

Comorbidities, Rheumatological diseases

Alias
UMLS CUI-1
C0419922
UMLS CUI-2
C0035435
Rheumatic disease (e.g. rheumatoid arthritis, vasculitis, spondyloarthritis, psoriatic arthritis)
Description

Comorbidities that existed before the positive testing for SARS-CoV-2 Unknown means that there is no access to the patient history

Data type

integer

Alias
UMLS CUI [1]
C0035435
UMLS CUI [2]
C0003873
UMLS CUI [3]
C0042384
UMLS CUI [4]
C0949690
UMLS CUI [5]
C0003872
Connective tissue disease (e.g. systemic lupus erythematosus, dermatomyositis, Sjögren's syndrome)
Description

Comorbidities that existed before the positive testing for SARS-CoV-2 Unknown means that there is no access to the patient history

Data type

integer

Alias
UMLS CUI [1]
C0009782
UMLS CUI [2]
C0409974
UMLS CUI [3]
C0011633
UMLS CUI [4]
C1527336
Comorbidities, Allergology
Description

Comorbidities, Allergology

Alias
UMLS CUI-1
C0009488
UMLS CUI-2
C0020517
Pollen sensitization
Description

Comorbidities that existed before the positive testing for SARS-CoV-2 Unknown means that there is no access to the patient history

Data type

integer

Alias
UMLS CUI [1]
C0740919
Dust mite senzitization
Description

Comorbidities that existed before the positive testing for SARS-CoV-2 Unknown means that there is no access to the patient history

Data type

integer

Alias
UMLS CUI [1]
C0339808
Other sensitization
Description

Comorbidities that existed before the positive testing for SARS-CoV-2 Unknown means that there is no access to the patient history

Data type

integer

Alias
UMLS CUI [1,1]
C0020517
UMLS CUI [1,2]
C0205394
Comorbidities, Other internal disorders
Description

Comorbidities, Other internal disorders

Alias
UMLS CUI-1
C0009488
UMLS CUI-2
C0205394
UMLS CUI-3
C0012634
UMLS CUI-4
C0205102
Peptic ulcer disease
Description

Comorbidities that existed before the positive testing for SARS-CoV-2 Unknown means that there is no access to the patient history

Data type

integer

Alias
UMLS CUI [1]
C0030920
Chronic liver disease
Description

Comorbidities that existed before the positive testing for SARS-CoV-2 Unknown means that there is no access to the patient history

Data type

integer

Alias
UMLS CUI [1]
C0341439
Liver cirrhosis
Description

Comorbidities that existed before the positive testing for SARS-CoV-2 Unknown means that there is no access to the patient history

Data type

integer

Alias
UMLS CUI [1]
C0023890
Diabetes, no end-organ damage
Description

Comorbidities that existed before the positive testing for SARS-CoV-2 Unknown means that there is no access to the patient history

Data type

integer

Alias
UMLS CUI [1,1]
C0011849
UMLS CUI [1,2]
C0743496
UMLS CUI [1,3]
C0332197
Diabetes, with end-organ damage
Description

Comorbidities that existed before the positive testing for SARS-CoV-2 Unknown means that there is no access to the patient history

Data type

integer

Alias
UMLS CUI [1,1]
C0011849
UMLS CUI [1,2]
C0743496
Chronic kidney disease
Description

Comorbidities that existed before the positive testing for SARS-CoV-2 Unknown means that there is no access to the patient history

Data type

integer

Alias
UMLS CUI [1]
C1561643
On dialysis
Description

Comorbidities that existed before the positive testing for SARS-CoV-2 Unknown means that there is no access to the patient history

Data type

integer

Alias
UMLS CUI [1]
C0011946
Comorbidities, Other conditions
Description

Comorbidities, Other conditions

Alias
UMLS CUI-1
C0009488
UMLS CUI-2
C0205394
Organ transplantation
Description

Comorbidities that existed before the positive testing for SARS-CoV-2 Unknown means that there is no access to the patient history

Data type

integer

Alias
UMLS CUI [1]
C0029216
HIV/AIDS
Description

Comorbidities that existed before the positive testing for SARS-CoV-2 Unknown means that there is no access to the patient history

Data type

integer

Alias
UMLS CUI [1]
C0019693
UMLS CUI [2]
C0001175
Traumatic injury (e.g. head, chest, abdominal and skeletal injuries)
Description

Comorbidities that existed before the positive testing for SARS-CoV-2 Unknown means that there is no access to the patient history

Data type

integer

Alias
UMLS CUI [1]
C3263723
UMLS CUI [2]
C0018674
UMLS CUI [3]
C0039980
UMLS CUI [4]
C0848377
UMLS CUI [5]
C0597457
Burn
Description

Comorbidities that existed before the positive testing for SARS-CoV-2 Unknown means that there is no access to the patient history

Data type

integer

Alias
UMLS CUI [1]
C0006434
Alcohol abuse
Description

Comorbidities that existed before the positive testing for SARS-CoV-2 Unknown means that there is no access to the patient history

Data type

integer

Alias
UMLS CUI [1]
C0085762
Body-Mass-Index (BMI)
Description

Body-Mass-Index (BMI)

Alias
UMLS CUI-1
C1305855
Body-Mass-Index (BMI)
Description

BMI = (weight in kilogram) / (height in meters)^2

Data type

integer

Alias
UMLS CUI [1]
C1305855
Smoking status
Description

Smoking status

Alias
UMLS CUI-1
C1519386
Smoking status
Description

Smoking in this context refers to regular cigarettes (no e-cigarettes)

Data type

integer

Alias
UMLS CUI [1]
C1519386
Use of e-cigarettes and / or vaporizer?
Description

Use of e-cigarettes and / or vaporizer?

Alias
UMLS CUI-1
C3849993
UMLS CUI-2
C4083280
Use of e-cigarettes and / or vaporizer?
Description

E-cigarettes and / or vaporizer

Data type

integer

Alias
UMLS CUI [1]
C3849993
UMLS CUI [2]
C4083280
Pre-existing treatment
Description

Pre-existing treatment

Alias
UMLS CUI-1
C0087111
ACE inhibitors (e.g. enalapril, captopril, most drugs ending on -pril)
Description

Following drugs were taken at the time of diagnosis

Data type

integer

Alias
UMLS CUI [1]
C0003015
UMLS CUI [2]
C0006938
UMLS CUI [3]
C0014025
AT-1 inhibitors (e.g. candesartan, losartan, most drugs ending on -sartan)
Description

Following drugs were taken at the time of diagnosis

Data type

integer

Alias
UMLS CUI [1]
C0521942
UMLS CUI [2]
C0717550
UMLS CUI [3]
C0126174
Statines (e.g. atorvastatin, pravastatin, most drugs ending on -statin)
Description

Following drugs were taken at the time of diagnosis

Data type

integer

Alias
UMLS CUI [1]
C0360714
UMLS CUI [2]
C0286651
UMLS CUI [3]
C0085542
Ibuprofen
Description

Following drugs were taken at the time of diagnosis

Data type

integer

Alias
UMLS CUI [1]
C0020740
Vitamin D
Description

Following drugs were taken at the time of diagnosis

Data type

integer

Alias
UMLS CUI [1]
C0420176
Vaccinated for COVID-19
Description

COVID-19 vaccination

Data type

integer

Alias
UMLS CUI [1]
C5203672
If 1 dosis administered, indicate the number of weeks since the last dosis
Description

Weeks since first dosis

Data type

text

Measurement units
  • weeks
Alias
UMLS CUI [1,1]
C1272706
UMLS CUI [1,2]
C1711239
UMLS CUI [1,3]
C0205435
UMLS CUI [1,4]
C5203672
weeks
If 2 dosis administered, indicate the number of weeks since the last dosis
Description

Weeks since second dosis

Data type

text

Measurement units
  • weeks
Alias
UMLS CUI [1,1]
C1272706
UMLS CUI [1,2]
C1711239
UMLS CUI [1,3]
C0205436
UMLS CUI [1,4]
C5203672
weeks
Vaccine used for COVID-19
Description

In case the vaccines used differed between the 1st and 2nd dose, please indicate the vaccines used separated by comma in other, please specify. In case no vaccination has been performed, indicate not done.

Data type

integer

Alias
UMLS CUI [1,1]
C5203672
UMLS CUI [1,2]
C0332307
Indicate other vaccine
Description

Other type of COVID-19 vaccination

Data type

text

Alias
UMLS CUI [1,1]
C5203672
UMLS CUI [1,2]
C0332307
UMLS CUI [1,3]
C0205394
Immunosuppressive medication in the past 3 months?
Description

Immunosuppressive medication in the past 3 months?

Alias
UMLS CUI-1
C0021081
UMLS CUI-2
C0332185
Immunosuppressive medication in the past 3 months?
Description

Consider drugs for treatment of cancer, rheumatological/inflammatory diseases, chronic inflammatory bowel disease, multiple sclerosis etc.

Data type

integer

Alias
UMLS CUI [1,1]
C0021081
UMLS CUI [1,2]
C0332185
Known colonisation with multi-resistant pathogens
Description

Known colonisation with multi-resistant pathogens

Alias
UMLS CUI-1
C3826980
UMLS CUI-2
C2747813
MRSA (Methicillin-resistant St. aureus)
Description

Please do only indicate colonization, super / coinfections are addressed in further questions.

Data type

integer

Alias
UMLS CUI [1,1]
C1265292
UMLS CUI [1,2]
C2747813
VRE (Vancomycin-resistant Enterococci)
Description

Please do only indicate colonization, super / coinfections are addressed in further questions.

Data type

integer

Alias
UMLS CUI [1,1]
C1265175
UMLS CUI [1,2]
C2747813
3rd generation cephalosporin-resistant enterobacteriacae (3GCREB)
Description

Please do only indicate colonization, super / coinfections are addressed in further questions.

Data type

integer

Alias
UMLS CUI [1,1]
C0014346
UMLS CUI [1,2]
C0304320
UMLS CUI [1,3]
C0013203
UMLS CUI [1,4]
C2747813
Other known colonisation
Description

Please do only indicate colonization, super / coinfections are addressed in further questions.

Data type

integer

Alias
UMLS CUI [1,1]
C0205394
UMLS CUI [1,2]
C2747813
Indicate other known colonisation
Description

Other known colonisation

Data type

text

Alias
UMLS CUI [1,1]
C3845569
UMLS CUI [1,2]
C2747813
Did the patient suffer from a life limiting disease with a prognosis of less than one year to live before first positive testing of SARS-CoV-2?
Description

Did the patient suffer from a life limiting disease with a prognosis of less than one year to live before first positive testing of SARS-CoV-2?

Alias
UMLS CUI-1
C0012634
UMLS CUI-2
C0439801
UMLS CUI-3
C0023671
UMLS CUI-4
C0332152
UMLS CUI-5
C5203676
UMLS CUI-6
C0039593
UMLS CUI-7
C1446409
Did the patient suffer from a life limiting disease with a prognosis of less than one year to live before first positive testing of SARS-CoV-2?
Description

Disease limiting life expectancy before positive SARS-CoV-2 testing

Data type

integer

Alias
UMLS CUI [1,1]
C0012634
UMLS CUI [1,2]
C0439801
UMLS CUI [1,3]
C0023671
UMLS CUI [1,4]
C0332152
UMLS CUI [1,5]
C5203676
UMLS CUI [1,6]
C0039593
UMLS CUI [1,7]
C1446409
Days of follow-up since the day the sample of the first positive SARS-CoV-2 result was taken
Description

Days of follow-up since the day the sample of the first positive SARS-CoV-2 result was taken

Alias
UMLS CUI-1
C1522577
UMLS CUI-2
C0449238
UMLS CUI-3
C0011900
UMLS CUI-4
C5203676
Indicate days of follow-up since the day the sample of the first positive SARS-CoV-2 result was taken
Description

Follow-up is meant in the context of the current COVID-19 treatment but does not include long-term follow-ups (e.g. for clinical studies). In case of inpatient settings end of follow-up is identical to discharge. In case of outpatient settings end of follow-up is identical to the last contact in the context of the current SARS-CoV-2 infection. In case of patient's death end of follow-up is identical to the day of death.

Data type

text

Measurement units
  • days
Alias
UMLS CUI [1,1]
C1522577
UMLS CUI [1,2]
C0449238
UMLS CUI [1,3]
C0011900
UMLS CUI [1,4]
C5203676
days
Last known status
Description

Last known status

Alias
UMLS CUI-1
C0699749
UMLS CUI-2
C0011008
UMLS CUI-3
C1517741
Last known status
Description

Uncomplicated asympotmatic patients enter recovery phase after 14 days of observation without disease progression. Indicate a last known status according to your information (e.g. in case of discharge, last documented status at dischage).

Data type

integer

Alias
UMLS CUI [1,1]
C0699749
UMLS CUI [1,2]
C0011008
UMLS CUI [1,3]
C1517741
Indicate other causes of death
Description

Indicate other causes of death

Data type

text

Alias
UMLS CUI [1,1]
C0007465
UMLS CUI [1,2]
C0205394
UMLS CUI [1,3]
C1521902
Context of diagnosis
Description

Context of diagnosis

Alias
UMLS CUI-1
C0011900
Month of first diagnosis
Description

Month of initial COVID-19 diagnosis

Data type

integer

Alias
UMLS CUI [1,1]
C0439231
UMLS CUI [1,2]
C0205265
UMLS CUI [1,3]
C0011900
UMLS CUI [1,4]
C5203676
Context of diagnosis
Description

Context of diagnosis

Data type

integer

Alias
UMLS CUI [1,1]
C0449255
UMLS CUI [1,2]
C0011900
UMLS CUI [1,3]
C5203670
Indicate other context of diagnosis
Description

Other context of diagnosis

Data type

text

Alias
UMLS CUI [1,1]
C0449255
UMLS CUI [1,2]
C0011900
UMLS CUI [1,3]
C5203670
UMLS CUI [1,4]
C0205394
Is the first known contact with infected person traceable?
Description

First known contact with COVID-19 infected person

Data type

integer

Alias
UMLS CUI [1,1]
C0205435
UMLS CUI [1,2]
C0332158
UMLS CUI [1,3]
C5203676
Indicate assumed days between contracting infection and diagnosis
Description

Indicate assumed days between contracting infection and diagnosis. Please keep our definition of diagnosis in mind: diagnosis is defined as the day the sample of the first positive SARS-CoV-2 result was taken.

Data type

text

Measurement units
  • days
Alias
UMLS CUI [1,1]
C0205435
UMLS CUI [1,2]
C0332158
UMLS CUI [1,3]
C5203676
UMLS CUI [1,4]
C2316983
UMLS CUI [1,5]
C1272706
UMLS CUI [1,6]
C1521902
days
Country of diagnosis
Description

ISO Alpha-3 code (e.g. Germany= DEU, Iceland= ISL, Spain= ESP)

Data type

text

Alias
UMLS CUI [1,1]
C0454664
UMLS CUI [1,2]
C0011900
UMLS CUI [1,3]
C5203676
Phase at diagnosis
Description

Please keep our definition of diagnosis in mind. Uncomplicated Phase: Asymtomatic OR Symptoms of upper respiratory tract infection Nausea, emesis, diarrhea Fever Complicated Phase: Need for new oxygen supplementation Clinically meaningful increase of prior oxygen home therapy paO2 at room air < 70 mmHg SO2 at room air < 90 % AST or ALT > 5x ULN New cardiac arrhythmia New pericardial effusion > 1 cm New heart failure with pulmonary edema, congestive hepatopathy or peripheral edema Critical Phase: Need for catecholamines Life-threatening cardiac arrhythmia Need for unplanned mechanical ventilation (invasive or non-invasive) Prolongation (> 24 h) of planned mechanical ventilation Liver failure with Quick < 50 % / INR > 3.5 qSOFA >= 2 Acute renal failure in need of dialysis Recovery Phase: Improvement by one degree of severity according to this scheme or discharge from hospital AND Defervescence AND No further progression or re-hospitalization

Data type

integer

Alias
UMLS CUI [1,1]
C0521117
UMLS CUI [1,2]
C5203676
UMLS CUI [1,3]
C0011900
How did the patient come to the health care facility?
Description

Facility as the place where the first positive PCR swab was taken. In case of transfer from another hospital, please indicate the respective means of transport (e.g. transport patient ambulance).

Data type

integer

Alias
UMLS CUI [1,1]
C3263562
UMLS CUI [1,2]
C0018704
UMLS CUI [2,1]
C0150390
UMLS CUI [2,2]
C0018704
Indicate other ways the patient come to the health care facility
Description

Indicate other methods of transport/arrival to health care facility

Data type

text

Alias
UMLS CUI [1,1]
C3263562
UMLS CUI [1,2]
C0018704
UMLS CUI [1,3]
C3845569
UMLS CUI [2,1]
C0150390
UMLS CUI [2,2]
C0018704
UMLS CUI [2,3]
C3845569
Reason for consultation / admission: COVID-19 or treatment for other medical conditions
Description

Please fill in ICD-10 code

Data type

text

Alias
UMLS CUI [1,1]
C0392360
UMLS CUI [1,2]
C0009818
UMLS CUI [2,1]
C0392360
UMLS CUI [2,2]
C0809949
UMLS CUI [3]
C5203670
UMLS CUI [4,1]
C0012634
UMLS CUI [4,2]
C0205394
UMLS CUI [4,3]
C0087111
UMLS CUI [5]
C2598420
Coded DRG
Description

Please note that a DRG has the structure: LetterNumberNumberLetter (e.g. A11A). Please do not provide the ICD10 here.

Data type

text

Alias
UMLS CUI [1]
C0011928
Details regarding the COVID-19 diagnosis
Description

Details regarding the COVID-19 diagnosis

Alias
UMLS CUI-1
C5203670
UMLS CUI-2
C1522508
Can the current SARS-CoV-2 infection be considered as a re-infection?
Description

Endogenous or exogenous re-infection can be considered in case of new positive SARS-CoV-2 virology after an interval of recovery.

Data type

integer

Alias
UMLS CUI [1,1]
C0521116
UMLS CUI [1,2]
C5203670
UMLS CUI [1,3]
C0205339
If re-infection, indicate the number of months since the recovery of the previous infection
Description

Indicate the number of months since the recovery of the previous infection, in case of less than 1 months indicate 0. If the number of months since the recovery is unknown, please indicate ND.

Data type

text

Measurement units
  • months
Alias
UMLS CUI [1,1]
C1272706
UMLS CUI [1,2]
C1711239
UMLS CUI [1,3]
C0205156
UMLS CUI [1,4]
C5203670
months
Is this case linked to a variant of concern (VOC) identified via sequencing?
Description

Variants of concern (VOC) are considered to increase transmissibility and deteriorate epidemiological situations. The below provided variants are the current 3 virus variants garnered widespread attention. Please consider the whole observational period in case sequencing has been performed in any phase of disease.

Data type

integer

Alias
UMLS CUI [1,1]
C0205419
UMLS CUI [1,2]
C2699424
UMLS CUI [1,3]
C5203676
UMLS CUI [1,4]
C0599161
Indicate other variant of concern
Description

Other variant of concern

Data type

text

Alias
UMLS CUI [1,1]
C0205419
UMLS CUI [1,2]
C2699424
UMLS CUI [1,3]
C5203676
UMLS CUI [1,4]
C0599161
UMLS CUI [1,5]
C0205394
Complications at baseline: Thrombotic and thromboembolic manifestations
Description

Complications at baseline: Thrombotic and thromboembolic manifestations

Alias
UMLS CUI-1
C0009566
UMLS CUI-2
C1442488
UMLS CUI-3
C0040053
UMLS CUI-4
C0040038
Abdominal thrombosis/thromboembolism (venous or arterial)
Description

Please indicate the complications on the day when the swab of the first positive testing for SARS-CoV-2 was taken.

Data type

integer

Alias
UMLS CUI [1,1]
C1442488
UMLS CUI [1,2]
C0151942
UMLS CUI [1,3]
C0000726
UMLS CUI [2,1]
C1442488
UMLS CUI [2,2]
C0042487
UMLS CUI [2,3]
C0000726
UMLS CUI [3,1]
C1442488
UMLS CUI [3,2]
C3544094
UMLS CUI [3,3]
C0000726
UMLS CUI [4,1]
C1442488
UMLS CUI [4,2]
C1861172
UMLS CUI [4,3]
C0000726
Myocardial infarction
Description

Please indicate the complications on the day when the swab of the first positive testing for SARS-CoV-2 was taken.

Data type

integer

Alias
UMLS CUI [1,1]
C1442488
UMLS CUI [1,2]
C0027051
Venous thrombosis, e.g. deep leg vein thrombosis
Description

Please indicate the complications on the day when the swab of the first positive testing for SARS-CoV-2 was taken.

Data type

integer

Alias
UMLS CUI [1,1]
C1442488
UMLS CUI [1,2]
C0042487
UMLS CUI [2,1]
C1442488
UMLS CUI [2,2]
C0149871
Pulmonary embolism
Description

Please indicate the complications on the day when the swab of the first positive testing for SARS-CoV-2 was taken.

Data type

integer

Alias
UMLS CUI [1,1]
C1442488
UMLS CUI [1,2]
C0034065
Microangiopathies and microthromboses
Description

Please indicate the complications on the day when the swab of the first positive testing for SARS-CoV-2 was taken.

Data type

integer

Alias
UMLS CUI [1,1]
C1442488
UMLS CUI [1,2]
C2717961
UMLS CUI [2,1]
C1442488
UMLS CUI [2,2]
C3686869
Complications at baseline: Neurological
Description

Complications at baseline: Neurological

Alias
UMLS CUI-1
C0235029
UMLS CUI-2
C1442488
Intracerebral bleeding
Description

Please indicate the complications on the day when the swab of the first positive testing for SARS-CoV-2 was taken.

Data type

integer

Alias
UMLS CUI [1,1]
C1442488
UMLS CUI [1,2]
C2937358
Ischemic Stroke
Description

Please indicate the complications on the day when the swab of the first positive testing for SARS-CoV-2 was taken.

Data type

integer

Alias
UMLS CUI [1,1]
C1442488
UMLS CUI [1,2]
C0948008
Meningitis / Encephalitis
Description

Please indicate the complications on the day when the swab of the first positive testing for SARS-CoV-2 was taken.

Data type

integer

Alias
UMLS CUI [1,1]
C1442488
UMLS CUI [1,2]
C0497299
Critical Illness Myopathy (CIM)
Description

Please indicate the complications on the day when the swab of the first positive testing for SARS-CoV-2 was taken.

Data type

integer

Alias
UMLS CUI [1,1]
C1442488
UMLS CUI [1,2]
C0010340
UMLS CUI [1,3]
C0026848
Critical Illness Polyneuropathy (CIP)
Description

Please indicate the complications on the day when the swab of the first positive testing for SARS-CoV-2 was taken.

Data type

integer

Alias
UMLS CUI [1,1]
C1442488
UMLS CUI [1,2]
C0010340
UMLS CUI [1,3]
C0152025
Seizure
Description

Please indicate the complications on the day when the swab of the first positive testing for SARS-CoV-2 was taken.

Data type

integer

Alias
UMLS CUI [1,1]
C1442488
UMLS CUI [1,2]
C0036572
Complications at baseline: Other severe organ damage
Description

Complications at baseline: Other severe organ damage

Alias
UMLS CUI-1
C0009566
UMLS CUI-2
C1442488
UMLS CUI-3
C0178784
UMLS CUI-4
C1883709
UMLS CUI-5
C0205082
UMLS CUI-6
C0205394
Acute renal failure
Description

Please indicate the complications on the day when the swab of the first positive testing for SARS-CoV-2 was taken.

Data type

integer

Alias
UMLS CUI [1,1]
C1442488
UMLS CUI [1,2]
C0022660
Severe liver failure
Description

Please indicate the complications on the day when the swab of the first positive testing for SARS-CoV-2 was taken.

Data type

integer

Alias
UMLS CUI [1,1]
C1442488
UMLS CUI [1,2]
C0085605
UMLS CUI [1,3]
C0205082
Congestive heart failure
Description

Please indicate the complications on the day when the swab of the first positive testing for SARS-CoV-2 was taken.

Data type

integer

Alias
UMLS CUI [1,1]
C1442488
UMLS CUI [1,2]
C0018802
Complications at baseline: Other
Description

Complications at baseline: Other

Alias
UMLS CUI-1
C0009566
UMLS CUI-2
C1442488
UMLS CUI-3
C0205394
Life threatening cardiac arrhythmia
Description

Please indicate the complications on the day when the swab of the first positive testing for SARS-CoV-2 was taken.

Data type

integer

Alias
UMLS CUI [1,1]
C1442488
UMLS CUI [1,2]
C0003811
UMLS CUI [1,3]
C2826244
Myocarditis
Description

Please indicate the complications on the day when the swab of the first positive testing for SARS-CoV-2 was taken.

Data type

integer

Alias
UMLS CUI [1,1]
C1442488
UMLS CUI [1,2]
C0027059
Vasculitis
Description

Please indicate the complications on the day when the swab of the first positive testing for SARS-CoV-2 was taken.

Data type

integer

Alias
UMLS CUI [1,1]
C1442488
UMLS CUI [1,2]
C0042384
Gastrointestinal bleeding
Description

Please indicate the complications on the day when the swab of the first positive testing for SARS-CoV-2 was taken.

Data type

integer

Alias
UMLS CUI [1,1]
C1442488
UMLS CUI [1,2]
C0017181
Endotracheal bleeding
Description

Please indicate the complications on the day when the swab of the first positive testing for SARS-CoV-2 was taken.

Data type

integer

Alias
UMLS CUI [1,1]
C1442488
UMLS CUI [1,2]
C0019080
UMLS CUI [1,3]
C0599554
Other complication
Description

Please indicate the complications on the day when the swab of the first positive testing for SARS-CoV-2 was taken.

Data type

integer

Alias
UMLS CUI [1,1]
C1442488
UMLS CUI [1,2]
C0009566
UMLS CUI [1,3]
C0205394
Indicate other complication
Description

Baseline: indicate other complication

Data type

text

Alias
UMLS CUI [1,1]
C1442488
UMLS CUI [1,2]
C0009566
UMLS CUI [1,3]
C3845569
Disease course within observational period
Description

Disease course within observational period

Alias
UMLS CUI-1
C0920316
UMLS CUI-2
C0699749
UMLS CUI-3
C1522577
UMLS CUI-4
C1442488
Presence of uncomplicated phase
Description

Please keep our definition of phases in mind. Note that ambulatory treatment implies an uncomplicated phase.

Data type

boolean

Alias
UMLS CUI [1,1]
C0443334
UMLS CUI [1,2]
C0205390
Uncomplicated phase, start day
Description

Please keep our definition of diagnosis in mind and provide days from DIAGNOSIS (day 0) until the START of each phase. If uncomplicated phase started before diagnosis, use negative days. Note that ambulatory treatment implies an uncomplicated phase.

Data type

text

Alias
UMLS CUI [1,1]
C0808070
UMLS CUI [1,2]
C0443334
UMLS CUI [1,3]
C0205390
UMLS CUI [1,4]
C1521902
Presence of complicated phase
Description

Please keep our definition of phases in mind.

Data type

boolean

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
Complicated phase, start day
Description

Please keep our definition of diagnosis in mind and provide days from DIAGNOSIS (day 0) until the START of each phase. If complicated phase started before diagnosis, use negative days.

Data type

text

Alias
UMLS CUI [1,1]
C0808070
UMLS CUI [1,2]
C0231242
UMLS CUI [1,3]
C0205390
UMLS CUI [1,4]
C1521902
Presence of critical phase
Description

Please keep our definition of phases in mind.

Data type

boolean

Alias
UMLS CUI [1,1]
C1511545
UMLS CUI [1,2]
C0205390
Critical phase, start day
Description

Please keep our definition of diagnosis in mind and provide days from DIAGNOSIS (day 0) until the START of each phase. If critical phase started before diagnosis, use negative days.

Data type

text

Alias
UMLS CUI [1,1]
C0808070
UMLS CUI [1,2]
C1511545
UMLS CUI [1,3]
C0205390
UMLS CUI [1,4]
C1521902
Presence of recovery phase
Description

Please keep our definition of phases in mind. Recovery does not necessarily mean the absence of all symptoms, but an improvement according to the delivered criteria. Recovery phase can be defined by discharge. Recovery phase in outpatient settings can be achieved by uncomplicated patients after 14 days of observation without disease progression.

Data type

boolean

Alias
UMLS CUI [1,1]
C2004454
UMLS CUI [1,2]
C0205390
Recovery phase, start day
Description

Please keep our definition of diagnosis in mind and provide days from DIAGNOSIS (day 0) until the START of each phase. If recovery phase is defined by discharge, the start of recovery phase is equal to the date of discharge.

Data type

text

Alias
UMLS CUI [1,1]
C0808070
UMLS CUI [1,2]
C2004454
UMLS CUI [1,3]
C0205390
UMLS CUI [1,4]
C1521902
Day of admission to hospital in reference to first SARS-CoV-2-detection (day 0)
Description

If admission has been before the detection, the day is negative. If there has been no admission to hospital, note ND.

Data type

text

Alias
UMLS CUI [1,1]
C0806429
UMLS CUI [1,2]
C1272706
UMLS CUI [1,3]
C5203676
UMLS CUI [1,4]
C1511790
Did the patient come through the emergency room?
Description

ER means a unit with possible emergency care in case of acute illnesses and injuries, including admission station and in some cases monitoring station and/or ICU.

Data type

integer

Alias
UMLS CUI [1,1]
C3263562
UMLS CUI [1,2]
C4291935
Duration (days) of...
Description

Duration (days) of...

Alias
UMLS CUI-1
C0449238
Overall inpatient stay
Description

Overall inpatient stay is the entire period from first admission (days before SARS-CoV-2 testing included) to final discharge including any short outpatient stay with re-hospitalization in between. If the respective health care option has not been applied, please indicate 0.

Data type

text

Measurement units
  • days
Alias
UMLS CUI [1,1]
C0420512
UMLS CUI [1,2]
C0023303
days
Intensive care unit (ICU) stay
Description

Indicate patient stay at Intensive care unit (ICU). If the respective health care option has not been applied, please indicate 0.

Data type

text

Measurement units
  • days
Alias
UMLS CUI [1,1]
C0085559
UMLS CUI [1,2]
C0023303
days
Intermediate care unit (IMCU) stay
Description

Indicate patient stay at Intermediate care unit (IMCU). If the respective health care option has not been applied, please indicate 0.

Data type

text

Measurement units
  • days
Alias
UMLS CUI [1,1]
C0021767
UMLS CUI [1,2]
C0023303
days
Invasive mechanical ventilation
Description

Indicate days of invasive mechanical ventilation. If the respective health care option has not been applied, please indicate 0.

Data type

text

Measurement units
  • days
Alias
UMLS CUI [1,1]
C0199470
UMLS CUI [1,2]
C0449238
days
ECMO support
Description

Indicate days on which the patient required ECMO support. If the respective health care option has not been applied, please indicate 0.

Data type

text

Measurement units
  • days
Alias
UMLS CUI [1,1]
C0015357
UMLS CUI [1,2]
C0449238
days
Non-invasive mechanical ventilation
Description

Indicate days of non-invasive mechanical ventilation. If the respective health care option has not been applied, please indicate 0.

Data type

text

Measurement units
  • days
Alias
UMLS CUI [1,1]
C1997883
UMLS CUI [1,2]
C0449238
days
Symptoms: Please click all symptoms which occurred in the respective clinical phase
Description

Symptoms: Please click all symptoms which occurred in the respective clinical phase

Alias
UMLS CUI-1
C1457887
Baseline (BL): None / asymptomatic
Description

Order of symptoms: upper-, lower respiratory, cardiac, gastrointestinal, musculoskeletal, systemic, neurological, other.

Data type

integer

Alias
UMLS CUI [1,1]
C1442488
UMLS CUI [1,2]
C1298908
UMLS CUI [1,3]
C0037088
UMLS CUI [2,1]
C1442488
UMLS CUI [2,2]
C0231221
Baseline (BL): Runny nose
Description

Order of symptoms: upper-, lower respiratory, cardiac, gastrointestinal, musculoskeletal, systemic, neurological, other.

Data type

integer

Alias
UMLS CUI [1,1]
C1442488
UMLS CUI [1,2]
C1260880
Baseline (BL): Sore throat
Description

Order of symptoms: upper-, lower respiratory, cardiac, gastrointestinal, musculoskeletal, systemic, neurological, other.

Data type

integer

Alias
UMLS CUI [1,1]
C1442488
UMLS CUI [1,2]
C0242429
Baseline (BL): Dry cough
Description

Order of symptoms: upper-, lower respiratory, cardiac, gastrointestinal, musculoskeletal, systemic, neurological, other.

Data type

integer

Alias
UMLS CUI [1,1]
C1442488
UMLS CUI [1,2]
C0850149
Baseline (BL): Productive cough
Description

Order of symptoms: upper-, lower respiratory, cardiac, gastrointestinal, musculoskeletal, systemic, neurological, other.

Data type

integer

Alias
UMLS CUI [1,1]
C1442488
UMLS CUI [1,2]
C0239134
Baseline (BL): Wheezing
Description

Order of symptoms: upper-, lower respiratory, cardiac, gastrointestinal, musculoskeletal, systemic, neurological, other.

Data type

integer

Alias
UMLS CUI [1,1]
C1442488
UMLS CUI [1,2]
C0043144
Baseline (BL): Dyspnoe
Description

Order of symptoms: upper-, lower respiratory, cardiac, gastrointestinal, musculoskeletal, systemic, neurological, other.

Data type

integer

Alias
UMLS CUI [1,1]
C1442488
UMLS CUI [1,2]
C0013404
Baseline (BL): Palpitations
Description

Order of symptoms: upper-, lower respiratory, cardiac, gastrointestinal, musculoskeletal, systemic, neurological, other.

Data type

integer

Alias
UMLS CUI [1,1]
C1442488
UMLS CUI [1,2]
C0030252
Baseline (BL): Diarrhea
Description

Order of symptoms: upper-, lower respiratory, cardiac, gastrointestinal, musculoskeletal, systemic, neurological, other.

Data type

integer

Alias
UMLS CUI [1,1]
C1442488
UMLS CUI [1,2]
C0011991
Baseline (BL): Nausea / Emesis
Description

Order of symptoms: upper-, lower respiratory, cardiac, gastrointestinal, musculoskeletal, systemic, neurological, other.

Data type

integer

Alias
UMLS CUI [1,1]
C1442488
UMLS CUI [1,2]
C0027497
UMLS CUI [2,1]
C1442488
UMLS CUI [2,2]
C0042963
Baseline (BL): Muscle aches
Description

Order of symptoms: upper-, lower respiratory, cardiac, gastrointestinal, musculoskeletal, systemic, neurological, other.

Data type

integer

Alias
UMLS CUI [1,1]
C1442488
UMLS CUI [1,2]
C0231528
Baseline (BL): Muscle weakness
Description

Order of symptoms: upper-, lower respiratory, cardiac, gastrointestinal, musculoskeletal, systemic, neurological, other.

Data type

integer

Alias
UMLS CUI [1,1]
C1442488
UMLS CUI [1,2]
C0151786
Baseline (BL): Fever
Description

Order of symptoms: upper-, lower respiratory, cardiac, gastrointestinal, musculoskeletal, systemic, neurological, other.

Data type

integer

Alias
UMLS CUI [1,1]
C1442488
UMLS CUI [1,2]
C0015967
Baseline (BL): Delirium
Description

Order of symptoms: upper-, lower respiratory, cardiac, gastrointestinal, musculoskeletal, systemic, neurological, other.

Data type

integer

Alias
UMLS CUI [1,1]
C1442488
UMLS CUI [1,2]
C0011206
Baseline (BL): Excessive tiredness
Description

Order of symptoms: upper-, lower respiratory, cardiac, gastrointestinal, musculoskeletal, systemic, neurological, other.

Data type

integer

Alias
UMLS CUI [1,1]
C1442488
UMLS CUI [1,2]
C0442802
UMLS CUI [1,3]
C0848717
Baseline (BL): Headache
Description

Order of symptoms: upper-, lower respiratory, cardiac, gastrointestinal, musculoskeletal, systemic, neurological, other.

Data type

integer

Alias
UMLS CUI [1,1]
C1442488
UMLS CUI [1,2]
C0018681
Baseline (BL): Meningism
Description

Order of symptoms: upper-, lower respiratory, cardiac, gastrointestinal, musculoskeletal, systemic, neurological, other.

Data type

integer

Alias
UMLS CUI [1,1]
C1442488
UMLS CUI [1,2]
C0025287
Baseline (BL): Smell disorder
Description

Order of symptoms: upper-, lower respiratory, cardiac, gastrointestinal, musculoskeletal, systemic, neurological, other.

Data type

integer

Alias
UMLS CUI [1,1]
C1442488
UMLS CUI [1,2]
C0553757
Baseline (BL): Taste disorder
Description

Order of symptoms: upper-, lower respiratory, cardiac, gastrointestinal, musculoskeletal, systemic, neurological, other.

Data type

integer

Alias
UMLS CUI [1,1]
C1442488
UMLS CUI [1,2]
C0549590
Baseline (BL): Other neurological symptoms
Description

Order of symptoms: upper-, lower respiratory, cardiac, gastrointestinal, musculoskeletal, systemic, neurological, other.

Data type

integer

Alias
UMLS CUI [1,1]
C1442488
UMLS CUI [1,2]
C0235031
UMLS CUI [1,3]
C0205394
Baseline (BL): Red eye
Description

Order of symptoms: upper-, lower respiratory, cardiac, gastrointestinal, musculoskeletal, systemic, neurological, other.

Data type

integer

Alias
UMLS CUI [1,1]
C1442488
UMLS CUI [1,2]
C0015392
UMLS CUI [1,3]
C0332575
Baseline (BL): Skin rash
Description

Order of symptoms: upper-, lower respiratory, cardiac, gastrointestinal, musculoskeletal, systemic, neurological, other.

Data type

integer

Alias
UMLS CUI [1,1]
C1442488
UMLS CUI [1,2]
C0015230
Baseline (BL): Swollen lymph nodes
Description

Order of symptoms: upper-, lower respiratory, cardiac, gastrointestinal, musculoskeletal, systemic, neurological, other.

Data type

integer

Alias
UMLS CUI [1,1]
C1442488
UMLS CUI [1,2]
C0497156
Uncomplicated (UC): None / asymptomatic
Description

Order of symptoms: upper-, lower respiratory, cardiac, gastrointestinal, musculoskeletal, systemic, neurological, other.

Data type

integer

Alias
UMLS CUI [1,1]
C0443334
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C1298908
UMLS CUI [1,4]
C0037088
UMLS CUI [2,1]
C0443334
UMLS CUI [2,2]
C0205390
UMLS CUI [2,3]
C0231221
Uncomplicated (UC): Runny nose
Description

Order of symptoms: upper-, lower respiratory, cardiac, gastrointestinal, musculoskeletal, systemic, neurological, other.

Data type

integer

Alias
UMLS CUI [1,1]
C0443334
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C1260880
Uncomplicated (UC): Sore throat
Description

Order of symptoms: upper-, lower respiratory, cardiac, gastrointestinal, musculoskeletal, systemic, neurological, other.

Data type

integer

Alias
UMLS CUI [1,1]
C0443334
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0242429
Uncomplicated (UC): Dry cough
Description

Order of symptoms: upper-, lower respiratory, cardiac, gastrointestinal, musculoskeletal, systemic, neurological, other.

Data type

integer

Alias
UMLS CUI [1,1]
C0443334
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0850149
Uncomplicated (UC): Productive cough
Description

Order of symptoms: upper-, lower respiratory, cardiac, gastrointestinal, musculoskeletal, systemic, neurological, other.

Data type

integer

Alias
UMLS CUI [1,1]
C0443334
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0239134
Uncomplicated (UC): Wheezing
Description

Order of symptoms: upper-, lower respiratory, cardiac, gastrointestinal, musculoskeletal, systemic, neurological, other.

Data type

integer

Alias
UMLS CUI [1,1]
C0443334
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0043144
Uncomplicated (UC): Dyspnoe
Description

Order of symptoms: upper-, lower respiratory, cardiac, gastrointestinal, musculoskeletal, systemic, neurological, other.

Data type

integer

Alias
UMLS CUI [1,1]
C0443334
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0013404
Uncomplicated (UC): Palpitations
Description

Order of symptoms: upper-, lower respiratory, cardiac, gastrointestinal, musculoskeletal, systemic, neurological, other.

Data type

integer

Alias
UMLS CUI [1,1]
C0443334
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0030252
Uncomplicated (UC): Diarrhea
Description

Order of symptoms: upper-, lower respiratory, cardiac, gastrointestinal, musculoskeletal, systemic, neurological, other.

Data type

integer

Alias
UMLS CUI [1,1]
C0443334
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0011991
Uncomplicated (UC): Nausea / Emesis
Description

Order of symptoms: upper-, lower respiratory, cardiac, gastrointestinal, musculoskeletal, systemic, neurological, other.

Data type

integer

Alias
UMLS CUI [1,1]
C0443334
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0027497
UMLS CUI [2,1]
C0443334
UMLS CUI [2,2]
C0205390
UMLS CUI [2,3]
C0042963
Uncomplicated (UC): Muscle aches
Description

Order of symptoms: upper-, lower respiratory, cardiac, gastrointestinal, musculoskeletal, systemic, neurological, other.

Data type

integer

Alias
UMLS CUI [1,1]
C0443334
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0231528
Uncomplicated (UC): Muscle weakness
Description

Order of symptoms: upper-, lower respiratory, cardiac, gastrointestinal, musculoskeletal, systemic, neurological, other.

Data type

integer

Alias
UMLS CUI [1,1]
C0443334
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0151786
Uncomplicated (UC): Fever
Description

Order of symptoms: upper-, lower respiratory, cardiac, gastrointestinal, musculoskeletal, systemic, neurological, other.

Data type

integer

Alias
UMLS CUI [1,1]
C0443334
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0015967
Uncomplicated (UC): Delirium
Description

Order of symptoms: upper-, lower respiratory, cardiac, gastrointestinal, musculoskeletal, systemic, neurological, other.

Data type

integer

Alias
UMLS CUI [1,1]
C0443334
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0011206
Uncomplicated (UC): Excessive tiredness
Description

Order of symptoms: upper-, lower respiratory, cardiac, gastrointestinal, musculoskeletal, systemic, neurological, other.

Data type

integer

Alias
UMLS CUI [1,1]
C0443334
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0442802
Uncomplicated (UC): Headache
Description

Order of symptoms: upper-, lower respiratory, cardiac, gastrointestinal, musculoskeletal, systemic, neurological, other.

Data type

integer

Alias
UMLS CUI [1,1]
C0443334
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0018681
Uncomplicated (UC): Meningism
Description

Order of symptoms: upper-, lower respiratory, cardiac, gastrointestinal, musculoskeletal, systemic, neurological, other.

Data type

integer

Alias
UMLS CUI [1,1]
C0443334
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0025287
Uncomplicated (UC): Smell disorder
Description

Order of symptoms: upper-, lower respiratory, cardiac, gastrointestinal, musculoskeletal, systemic, neurological, other.

Data type

integer

Alias
UMLS CUI [1,1]
C0443334
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0553757
Uncomplicated (UC): Taste disorder
Description

Order of symptoms: upper-, lower respiratory, cardiac, gastrointestinal, musculoskeletal, systemic, neurological, other.

Data type

integer

Alias
UMLS CUI [1,1]
C0443334
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0549590
Uncomplicated (UC): Other neurological symptoms
Description

Order of symptoms: upper-, lower respiratory, cardiac, gastrointestinal, musculoskeletal, systemic, neurological, other.

Data type

integer

Alias
UMLS CUI [1,1]
C0443334
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0235031
UMLS CUI [1,4]
C0205394
Uncomplicated (UC): Red eye
Description

Order of symptoms: upper-, lower respiratory, cardiac, gastrointestinal, musculoskeletal, systemic, neurological, other.

Data type

integer

Alias
UMLS CUI [1,1]
C0443334
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0015392
UMLS CUI [1,4]
C0332575
Uncomplicated (UC): Skin rash
Description

Order of symptoms: upper-, lower respiratory, cardiac, gastrointestinal, musculoskeletal, systemic, neurological, other.

Data type

integer

Alias
UMLS CUI [1,1]
C0443334
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0015230
Uncomplicated (UC): Swollen lymph nodes
Description

Order of symptoms: upper-, lower respiratory, cardiac, gastrointestinal, musculoskeletal, systemic, neurological, other.

Data type

integer

Alias
UMLS CUI [1,1]
C0443334
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0497156
Complicated (CO): None / asymptomatic
Description

Order of symptoms: upper-, lower respiratory, cardiac, gastrointestinal, musculoskeletal, systemic, neurological, other.

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C1298908
UMLS CUI [1,4]
C0037088
UMLS CUI [2,1]
C0231242
UMLS CUI [2,2]
C0205390
UMLS CUI [2,3]
C0231221
Complicated (CO): Runny nose
Description

Order of symptoms: upper-, lower respiratory, cardiac, gastrointestinal, musculoskeletal, systemic, neurological, other.

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C1260880
Complicated (CO): Sore throat
Description

Order of symptoms: upper-, lower respiratory, cardiac, gastrointestinal, musculoskeletal, systemic, neurological, other.

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0242429
Complicated (CO): Dry cough
Description

Order of symptoms: upper-, lower respiratory, cardiac, gastrointestinal, musculoskeletal, systemic, neurological, other.

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0850149
Complicated (CO): Productive cough
Description

Order of symptoms: upper-, lower respiratory, cardiac, gastrointestinal, musculoskeletal, systemic, neurological, other.

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0239134
Complicated (CO): Wheezing
Description

Order of symptoms: upper-, lower respiratory, cardiac, gastrointestinal, musculoskeletal, systemic, neurological, other.

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0043144
Complicated (CO): Dyspnoe
Description

Order of symptoms: upper-, lower respiratory, cardiac, gastrointestinal, musculoskeletal, systemic, neurological, other.

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0013404
Complicated (CO): Palpitations
Description

Order of symptoms: upper-, lower respiratory, cardiac, gastrointestinal, musculoskeletal, systemic, neurological, other.

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0030252
Complicated (CO): Diarrhea
Description

Order of symptoms: upper-, lower respiratory, cardiac, gastrointestinal, musculoskeletal, systemic, neurological, other.

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0011991
Complicated (CO): Nausea / Emesis
Description

Order of symptoms: upper-, lower respiratory, cardiac, gastrointestinal, musculoskeletal, systemic, neurological, other.

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0027497
UMLS CUI [2,1]
C0231242
UMLS CUI [2,2]
C0205390
UMLS CUI [2,3]
C0042963
Complicated (CO): Muscle aches
Description

Order of symptoms: upper-, lower respiratory, cardiac, gastrointestinal, musculoskeletal, systemic, neurological, other.

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0231528
Complicated (CO): Muscle weakness
Description

Order of symptoms: upper-, lower respiratory, cardiac, gastrointestinal, musculoskeletal, systemic, neurological, other.

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0151786
Complicated (CO): Fever
Description

Order of symptoms: upper-, lower respiratory, cardiac, gastrointestinal, musculoskeletal, systemic, neurological, other.

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0015967
Complicated (CO): Delirium
Description

Order of symptoms: upper-, lower respiratory, cardiac, gastrointestinal, musculoskeletal, systemic, neurological, other.

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0011206
Complicated (CO): Excessive tiredness
Description

Order of symptoms: upper-, lower respiratory, cardiac, gastrointestinal, musculoskeletal, systemic, neurological, other.

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0442802
Complicated (CO): Headache
Description

Order of symptoms: upper-, lower respiratory, cardiac, gastrointestinal, musculoskeletal, systemic, neurological, other.

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0018681
Complicated (CO): Meningism
Description

Order of symptoms: upper-, lower respiratory, cardiac, gastrointestinal, musculoskeletal, systemic, neurological, other.

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0025287
Complicated (CO): Smell disorder
Description

Order of symptoms: upper-, lower respiratory, cardiac, gastrointestinal, musculoskeletal, systemic, neurological, other.

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0553757
Complicated (CO): Taste disorder
Description

Order of symptoms: upper-, lower respiratory, cardiac, gastrointestinal, musculoskeletal, systemic, neurological, other.

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0549590
Complicated (CO): Other neurological symptoms
Description

Order of symptoms: upper-, lower respiratory, cardiac, gastrointestinal, musculoskeletal, systemic, neurological, other.

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0235031
UMLS CUI [1,4]
C0205394
Complicated (CO): Red eye
Description

Order of symptoms: upper-, lower respiratory, cardiac, gastrointestinal, musculoskeletal, systemic, neurological, other.

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0015392
UMLS CUI [1,4]
C0332575
Complicated (CO): Skin rash
Description

Order of symptoms: upper-, lower respiratory, cardiac, gastrointestinal, musculoskeletal, systemic, neurological, other.

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0015230
Complicated (CO): Swollen lymph nodes
Description

Order of symptoms: upper-, lower respiratory, cardiac, gastrointestinal, musculoskeletal, systemic, neurological, other.

Data type

integer

Alias
UMLS CUI [1,1]
C0231242
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0497156
Critical (CR): None / asymptomatic
Description

Order of symptoms: upper-, lower respiratory, cardiac, gastrointestinal, musculoskeletal, systemic, neurological, other.

Data type

integer

Alias
UMLS CUI [1,1]
C1511545
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C1298908
UMLS CUI [1,4]
C0037088
UMLS CUI [2,1]
C1511545
UMLS CUI [2,2]
C0205390
UMLS CUI [2,3]
C0231221
Critical (CR): Runny nose
Description

Order of symptoms: upper-, lower respiratory, cardiac, gastrointestinal, musculoskeletal, systemic, neurological, other.

Data type

integer

Alias
UMLS CUI [1,1]
C1511545
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C1260880
Critical (CR): Sore throat
Description

Order of symptoms: upper-, lower respiratory, cardiac, gastrointestinal, musculoskeletal, systemic, neurological, other.

Data type

integer

Alias
UMLS CUI [1,1]
C1511545
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0242429
Critical (CR): Dry cough
Description

Order of symptoms: upper-, lower respiratory, cardiac, gastrointestinal, musculoskeletal, systemic, neurological, other.

Data type

integer

Alias
UMLS CUI [1,1]
C1511545
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0850149
Critical (CR): Productive cough
Description

Order of symptoms: upper-, lower respiratory, cardiac, gastrointestinal, musculoskeletal, systemic, neurological, other.

Data type

integer

Alias
UMLS CUI [1,1]
C1511545
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0239134
Critical (CR): Wheezing
Description

Order of symptoms: upper-, lower respiratory, cardiac, gastrointestinal, musculoskeletal, systemic, neurological, other.

Data type

integer

Alias
UMLS CUI [1,1]
C1511545
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0043144
Critical (CR): Dyspnoe
Description

Order of symptoms: upper-, lower respiratory, cardiac, gastrointestinal, musculoskeletal, systemic, neurological, other.

Data type

integer

Alias
UMLS CUI [1,1]
C1511545
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0013404
Critical (CR): Palpitations
Description

Order of symptoms: upper-, lower respiratory, cardiac, gastrointestinal, musculoskeletal, systemic, neurological, other.

Data type

integer

Alias
UMLS CUI [1,1]
C1511545
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0030252
Critical (CR): Diarrhea
Description

Order of symptoms: upper-, lower respiratory, cardiac, gastrointestinal, musculoskeletal, systemic, neurological, other.

Data type

integer

Alias
UMLS CUI [1,1]
C1511545
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0011991
Critical (CR): Nausea / Emesis
Description

Order of symptoms: upper-, lower respiratory, cardiac, gastrointestinal, musculoskeletal, systemic, neurological, other.

Data type

integer

Alias
UMLS CUI [1,1]
C1511545
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0027497
UMLS CUI [2,1]
C1511545
UMLS CUI [2,2]
C0205390
UMLS CUI [2,3]
C0042963
Critical (CR): Muscle aches
Description

Order of symptoms: upper-, lower respiratory, cardiac, gastrointestinal, musculoskeletal, systemic, neurological, other.

Data type

integer

Alias
UMLS CUI [1,1]
C1511545
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0231528
Critical (CR): Muscle weakness
Description

Order of symptoms: upper-, lower respiratory, cardiac, gastrointestinal, musculoskeletal, systemic, neurological, other.

Data type

integer

Alias
UMLS CUI [1,1]
C1511545
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0151786
Critical (CR): Fever
Description

Order of symptoms: upper-, lower respiratory, cardiac, gastrointestinal, musculoskeletal, systemic, neurological, other.

Data type

integer

Alias
UMLS CUI [1,1]
C1511545
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0015967
Critical (CR): Delirium
Description

Order of symptoms: upper-, lower respiratory, cardiac, gastrointestinal, musculoskeletal, systemic, neurological, other.

Data type

integer

Alias
UMLS CUI [1,1]
C1511545
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0011206
Critical (CR): Excessive tiredness
Description

Order of symptoms: upper-, lower respiratory, cardiac, gastrointestinal, musculoskeletal, systemic, neurological, other.

Data type

integer

Alias
UMLS CUI [1,1]
C1511545
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0442802
Critical (CR): Headache
Description

Order of symptoms: upper-, lower respiratory, cardiac, gastrointestinal, musculoskeletal, systemic, neurological, other.

Data type

integer

Alias
UMLS CUI [1,1]
C1511545
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0018681
Critical (CR): Meningism
Description

Order of symptoms: upper-, lower respiratory, cardiac, gastrointestinal, musculoskeletal, systemic, neurological, other.

Data type

integer

Alias
UMLS CUI [1,1]
C1511545
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0025287
Critical (CR): Smell disorder
Description

Order of symptoms: upper-, lower respiratory, cardiac, gastrointestinal, musculoskeletal, systemic, neurological, other.

Data type

integer

Alias
UMLS CUI [1,1]
C1511545
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0553757
Critical (CR): Taste disorder
Description

Order of symptoms: upper-, lower respiratory, cardiac, gastrointestinal, musculoskeletal, systemic, neurological, other.

Data type

integer

Alias
UMLS CUI [1,1]
C1511545
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0549590
Critical (CR): Other neurological symptoms
Description

Order of symptoms: upper-, lower respiratory, cardiac, gastrointestinal, musculoskeletal, systemic, neurological, other.

Data type

integer

Alias
UMLS CUI [1,1]
C1511545
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0235031
UMLS CUI [1,4]
C0205394
Critical (CR): Red eye
Description

Order of symptoms: upper-, lower respiratory, cardiac, gastrointestinal, musculoskeletal, systemic, neurological, other.

Data type

integer

Alias
UMLS CUI [1,1]
C1511545
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0015392
UMLS CUI [1,4]
C0332575
Critical (CR): Skin rash
Description

Order of symptoms: upper-, lower respiratory, cardiac, gastrointestinal, musculoskeletal, systemic, neurological, other.

Data type

integer

Alias
UMLS CUI [1,1]
C1511545
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0015230
Critical (CR): Swollen lymph nodes
Description

Order of symptoms: upper-, lower respiratory, cardiac, gastrointestinal, musculoskeletal, systemic, neurological, other.

Data type

integer

Alias
UMLS CUI [1,1]
C1511545
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0497156
Vital signs
Description

Vital signs

Alias
UMLS CUI-1
C0518766
Systolic BP at Baseline
Description

Please indicate values determined closest to the first positive PCR. If values were not determined within the first 48 hours, report as "Not done". You will have the opportunity to document further values later.

Data type

integer

Alias
UMLS CUI [1,1]
C1442488
UMLS CUI [1,2]
C0871470
Diastolic BP at Baseline
Description

Please indicate values determined closest to the first positive PCR. If values were not determined within the first 48 hours, report as "Not done". You will have the opportunity to document further values later.

Data type

integer

Alias
UMLS CUI [1,1]
C1442488
UMLS CUI [1,2]
C0428883
Pulse at Baseline
Description

Please indicate values determined closest to the first positive PCR. If values were not determined within the first 48 hours, report as "Not done". You will have the opportunity to document further values later.

Data type

integer

Alias
UMLS CUI [1,1]
C1442488
UMLS CUI [1,2]
C0232117
SO2 at Baseline
Description

Please indicate values determined closest to the first positive PCR. If values were not determined within the first 48 hours, report as "Not done". You will have the opportunity to document further values later.

Data type

integer

Alias
UMLS CUI [1,1]
C1442488
UMLS CUI [1,2]
C0523807
paO2 at Baseline
Description

Please indicate values determined closest to the first positive PCR. If values were not determined within the first 48 hours, report as "Not done". You will have the opportunity to document further values later.

Data type

integer

Alias
UMLS CUI [1,1]
C1442488
UMLS CUI [1,2]
C0391840
paCO2 at Baseline
Description

Please indicate values determined closest to the first positive PCR. If values were not determined within the first 48 hours, report as "Not done". You will have the opportunity to document further values later.

Data type

integer

Alias
UMLS CUI [1,1]
C1442488
UMLS CUI [1,2]
C1822070
Temperature at Baseline
Description

Please indicate values determined closest to the first positive PCR. If values were not determined within the first 48 hours, report as "Not done". You will have the opportunity to document further values later.

Data type

integer

Alias
UMLS CUI [1,1]
C1442488
UMLS CUI [1,2]
C0005903
Respiratory rate / minute at Baseline
Description

Please indicate values determined closest to the first positive PCR. If values were not determined within the first 48 hours, report as "Not done". You will have the opportunity to document further values later.

Data type

integer

Alias
UMLS CUI [1,1]
C1442488
UMLS CUI [1,2]
C0231832
Glasgow Coma Scale at Baseline
Description

Please indicate values determined closest to the first positive PCR. If values were not determined within the first 48 hours, report as "Not done". You will have the opportunity to document further values later.

Data type

integer

Alias
UMLS CUI [1,1]
C1442488
UMLS CUI [1,2]
C1271007
Lung ultrasound results at SARS-CoV-2 detection
Description

Lung ultrasound results at SARS-CoV-2 detection

Alias
UMLS CUI-1
C0203463
UMLS CUI-2
C0562508
UMLS CUI-3
C1274040
UMLS CUI-4
C5203670
B lines (multifocal, discrete or confluent)
Description

Please indicate the results of a lung ultrasound closest to the first positive PCR. If lung ultrasound was not done within the first 48 hours, report as "not done". You will have the opportunity to document further results later.

Data type

boolean

Alias
UMLS CUI [1,1]
C1442488
UMLS CUI [1,2]
C0203463
UMLS CUI [1,3]
C3846158
Confluent B lines
Description

Please indicate the results of a lung ultrasound closest to the first positive PCR. If lung ultrasound was not done within the first 48 hours, report as "not done". You will have the opportunity to document further results later.

Data type

boolean

Alias
UMLS CUI [1,1]
C1442488
UMLS CUI [1,2]
C0203463
UMLS CUI [1,3]
C3846158
UMLS CUI [1,4]
C0205200
Consolidation
Description

Please indicate the results of a lung ultrasound closest to the first positive PCR. If lung ultrasound was not done within the first 48 hours, report as "not done". You will have the opportunity to document further results later.

Data type

boolean

Alias
UMLS CUI [1,1]
C1442488
UMLS CUI [1,2]
C0203463
UMLS CUI [1,3]
C0521530
Multilobar distribution of abnormalities
Description

Please indicate the results of a lung ultrasound closest to the first positive PCR. If lung ultrasound was not done within the first 48 hours, report as "not done". You will have the opportunity to document further results later.

Data type

boolean

Alias
UMLS CUI [1,1]
C1442488
UMLS CUI [1,2]
C0203463
UMLS CUI [1,3]
C0439064
UMLS CUI [1,4]
C1522010
UMLS CUI [1,5]
C1704711
UMLS CUI [1,6]
C1704258
Small lesions
Description

Please indicate the results of a lung ultrasound closest to the first positive PCR. If lung ultrasound was not done within the first 48 hours, report as "not done". You will have the opportunity to document further results later.

Data type

boolean

Alias
UMLS CUI [1,1]
C1442488
UMLS CUI [1,2]
C0203463
UMLS CUI [1,3]
C0700321
UMLS CUI [1,4]
C0221198
Thickened pleural line
Description

Please indicate the results of a lung ultrasound closest to the first positive PCR. If lung ultrasound was not done within the first 48 hours, report as "not done". You will have the opportunity to document further results later.

Data type

boolean

Alias
UMLS CUI [1,1]
C1442488
UMLS CUI [1,2]
C0203463
UMLS CUI [1,3]
C0264545
Indicate other relevant lung ultrasound results
Description

Please indicate the results of a lung ultrasound closest to the first positive PCR. If lung ultrasound was not done within the first 48 hours, report as "not done". You will have the opportunity to document further results later.

Data type

boolean

Alias
UMLS CUI [1,1]
C1442488
UMLS CUI [1,2]
C0203463
UMLS CUI [1,3]
C1274040
UMLS CUI [1,4]
C0205394
No abnormal findings
Description

Please indicate the results of a lung ultrasound closest to the first positive PCR. If lung ultrasound was not done within the first 48 hours, report as "not done". You will have the opportunity to document further results later.

Data type

boolean

Alias
UMLS CUI [1,1]
C1442488
UMLS CUI [1,2]
C0205307
UMLS CUI [1,3]
C0203463
Not done
Description

Please indicate the results of a lung ultrasound closest to the first positive PCR. If lung ultrasound was not done within the first 48 hours, report as "not done". You will have the opportunity to document further results later.

Data type

boolean

Alias
UMLS CUI [1,1]
C1442488
UMLS CUI [1,2]
C0203463
UMLS CUI [1,3]
C1272696
Chest CT results at SARS-CoV-2 detection
Description

Chest CT results at SARS-CoV-2 detection

Alias
UMLS CUI-1
C1442488
UMLS CUI-2
C0202823
UMLS CUI-3
C1274040
UMLS CUI-4
C5203676
UMLS CUI-5
C1511790
Air trapping
Description

Please indicate the results of the CT / x-ray closest to the first positive PCR. If CT / x-ray was not done within the first 48 hours, report as "not done".

Data type

boolean

Alias
UMLS CUI [1,1]
C1442488
UMLS CUI [1,2]
C0231819
Areas of consolidation
Description

Please indicate the results of the CT / x-ray closest to the first positive PCR. If CT / x-ray was not done within the first 48 hours, report as "not done".

Data type

boolean

Alias
UMLS CUI [1,1]
C1442488
UMLS CUI [1,2]
C0521530
UMLS CUI [1,3]
C0205146
Bronchiolitis
Description

Please indicate the results of the CT / x-ray closest to the first positive PCR. If CT / x-ray was not done within the first 48 hours, report as "not done".

Data type

boolean

Alias
UMLS CUI [1,1]
C1442488
UMLS CUI [1,2]
C0006271
Crazy paving pattern
Description

Please indicate the results of the CT / x-ray closest to the first positive PCR. If CT / x-ray was not done within the first 48 hours, report as "not done".

Data type

boolean

Alias
UMLS CUI [1,1]
C1442488
UMLS CUI [1,2]
C4476749
Ground glass opacities
Description

Please indicate the results of the CT / x-ray closest to the first positive PCR. If CT / x-ray was not done within the first 48 hours, report as "not done".

Data type

boolean

Alias
UMLS CUI [1,1]
C1442488
UMLS CUI [1,2]
C3827002
Interlobular septal thickening
Description

Please indicate the results of the CT / x-ray closest to the first positive PCR. If CT / x-ray was not done within the first 48 hours, report as "not done".

Data type

boolean

Alias
UMLS CUI [1,1]
C1442488
UMLS CUI [1,2]
C4280727
Nodulary lesions
Description

Please indicate the results of the CT / x-ray closest to the first positive PCR. If CT / x-ray was not done within the first 48 hours, report as "not done".

Data type

boolean

Alias
UMLS CUI [1,1]
C1442488
UMLS CUI [1,2]
C1518345
Pleural effusion
Description

Please indicate the results of the CT / x-ray closest to the first positive PCR. If CT / x-ray was not done within the first 48 hours, report as "not done".

Data type

boolean

Alias
UMLS CUI [1,1]
C1442488
UMLS CUI [1,2]
C0032227
Chest x-ray done
Description

Baseline: Chest x-ray result

Data type

boolean

Alias
UMLS CUI [1,1]
C1442488
UMLS CUI [1,2]
C0039985
UMLS CUI [1,3]
C1274040
Indicate Chest x-ray results
Description

Please indicate the results of the x-ray closest to the first positive PCR. If x-ray was not done within the first 48 hours, report as "not done".

Data type

text

Alias
UMLS CUI [1,1]
C1442488
UMLS CUI [1,2]
C0039985
UMLS CUI [1,3]
C1274040
UMLS CUI [1,4]
C1521902
Other relevant CT results
Description

Please indicate the results of the CT closest to the first positive PCR. If CT was not done within the first 48 hours, report as "not done".

Data type

boolean

Alias
UMLS CUI [1,1]
C1442488
UMLS CUI [1,2]
C0040405
UMLS CUI [1,3]
C1274040
UMLS CUI [1,4]
C2826293
UMLS CUI [1,5]
C0205394
Indicate other relevant CT results
Description

Baseline: Indicate other relevant CT results

Data type

text

Alias
UMLS CUI [1,1]
C1442488
UMLS CUI [1,2]
C0040405
UMLS CUI [1,3]
C1274040
UMLS CUI [1,4]
C2826293
UMLS CUI [1,5]
C0205394
UMLS CUI [1,6]
C1521902
Normal CT
Description

Please indicate the results of the CT closest to the first positive PCR. If CT was not done within the first 48 hours, report as "not done".

Data type

boolean

Alias
UMLS CUI [1,1]
C1442488
UMLS CUI [1,2]
C0040405
UMLS CUI [1,3]
C0205307
Not done
Description

If CT / x-ray was not done within the first 48 hours, report as "not done".

Data type

boolean

Alias
UMLS CUI [1,1]
C1442488
UMLS CUI [1,2]
C0040405
UMLS CUI [1,3]
C1272696
Heart function: Ejection fraction (EF) at SARS-CoV-2 detection
Description

Heart function: Ejection fraction (EF) at SARS-CoV-2 detection

Alias
UMLS CUI-1
C0232164
UMLS CUI-2
C0013516
UMLS CUI-3
C0232174
UMLS CUI-4
C1511790
UMLS CUI-5
C5203676
Heart function: Ejection fraction (EF) at SARS-CoV-2 detection
Description

Echo results. If values were not determined within the first 48 hours, report as "not done".

Data type

integer

Alias
UMLS CUI [1,1]
C1442488
UMLS CUI [1,2]
C0232164
UMLS CUI [1,3]
C0013516
UMLS CUI [1,4]
C0232174
UMLS CUI [1,5]
C1511790
UMLS CUI [1,6]
C5203676
Has a cardiovascular magnetic resonance imaging (CMR) been performed in any clinical phase?
Description

Has a cardiovascular magnetic resonance imaging (CMR) been performed in any clinical phase?

Alias
UMLS CUI-1
C3873775
UMLS CUI-2
C0205390
UMLS CUI-3
C0205210
UMLS CUI-4
C1552551
Has a cardiovascular magnetic resonance imaging (CMR) been performed in any clinical phase?
Description

Cardiovascular magnetic resonance imaging system performed in any clinical phase

Data type

integer

Alias
UMLS CUI [1,1]
C3873775
UMLS CUI [1,2]
C0205390
UMLS CUI [1,3]
C0205210
UMLS CUI [1,4]
C1552551
Has neurological diagnostic taken place in the various phases?
Description

Has neurological diagnostic taken place in the various phases?

Alias
UMLS CUI-1
C0852602
UMLS CUI-2
C1552551
UMLS CUI-3
C0205390
Neurological diagnostic at Baseline
Description

E.g. cCT, cMRI, EEG, Electrophysiology

Data type

integer

Alias
UMLS CUI [1,1]
C0852602
UMLS CUI [1,2]
C1442488
Neurological diagnostic at Uncomplicated phase
Description

E.g. cCT, cMRI, EEG, Electrophysiology

Data type

integer

Alias
UMLS CUI [1,1]
C0852602
UMLS CUI [1,2]
C0443334
UMLS CUI [1,3]
C0205390
Neurological diagnostic at Complicated phase
Description

E.g. cCT, cMRI, EEG, Electrophysiology

Data type

integer

Alias
UMLS CUI [1,1]
C0852602
UMLS CUI [1,2]
C0231242
UMLS CUI [1,3]
C0205390
Neurological diagnostic at Critical phase
Description

E.g. cCT, cMRI, EEG, Electrophysiology

Data type

integer

Alias
UMLS CUI [1,1]
C0852602
UMLS CUI [1,2]
C1511545
UMLS CUI [1,3]
C0205390
Was complementary and/or integrative medicine (CIM) used in any phase?
Description

Was complementary and/or integrative medicine (CIM) used in any phase?

Alias
UMLS CUI-1
C4053461
UMLS CUI-2
C0205390
UMLS CUI-3
C1552551
Was complementary and/or integrative medicine (CIM) used in any phase?
Description

E.g. Naturopathy, wraps and pads, Phytotherapy

Data type

integer

Alias
UMLS CUI [1]
C4053461
Was limitation of therapy discussed at any time during the SARS-CoV-2 infection?
Description

Was limitation of therapy discussed at any time during the SARS-CoV-2 infection?

Alias
UMLS CUI-1
C0557061
UMLS CUI-2
C0449295
UMLS CUI-3
C0087111
UMLS CUI-4
C0347984
UMLS CUI-5
C5203676
Was limitation of therapy discussed at any time during the SARS-CoV-2 infection?
Description

Discussion of limitation of therapy during SARS-CoV-2 infection

Data type

integer

Alias
UMLS CUI [1,1]
C0557061
UMLS CUI [1,2]
C0449295
UMLS CUI [1,3]
C0087111
UMLS CUI [1,4]
C0347984
UMLS CUI [1,5]
C5203676
Did the patient receive specialist palliative care during the SARS-CoV-2 infection?
Description

Did the patient receive specialist palliative care during the SARS-CoV-2 infection?

Alias
UMLS CUI-1
C5203676
UMLS CUI-2
C0030231
Did the patient receive specialist palliative care during the SARS-CoV-2 infection?
Description

Specialist palliative care includes PCU (palliative care unit), PCHT (palliative care hospital team), palliative home care team, inpatient hospice. Please do also keep current patients in mind receiving palliative care at any point.

Data type

integer

Alias
UMLS CUI [1,1]
C5203676
UMLS CUI [1,2]
C0030231
Has the patient signed a general agreement to share data for scientific purposes?
Description

Has the patient signed a general agreement to share data for scientific purposes?

Alias
UMLS CUI-1
C0680240
UMLS CUI-2
C0035168
UMLS CUI-3
C2713450
Yes, to share data
Description

Yes, to share data

Data type

boolean

Alias
UMLS CUI [1,1]
C0680240
UMLS CUI [1,2]
C0035168
UMLS CUI [1,3]
C2713450
Yes, to share biomaterial samples
Description

Yes, to share biomaterial samples

Data type

boolean

Alias
UMLS CUI [1,1]
C0680240
UMLS CUI [1,2]
C2347026
UMLS CUI [1,3]
C0457083
No
Description

No, to share biomaterial samples

Data type

boolean

Alias
UMLS CUI [1,1]
C0680240
UMLS CUI [1,2]
C0035168
UMLS CUI [1,3]
C2713450
UMLS CUI [1,4]
C1298908
Unknown
Description

Agreement to share biomaterial samples, unknown

Data type

boolean

Alias
UMLS CUI [1,1]
C2347026
UMLS CUI [1,2]
C0470187
UMLS CUI [1,3]
C0035168
UMLS CUI [1,4]
C0439673
Is biomaterial of this patient available for research proposes?
Description

Is biomaterial of this patient available for research proposes?

Alias
UMLS CUI-1
C2347026
UMLS CUI-2
C0470187
UMLS CUI-3
C0035168
Serum
Description

Serum

Data type

boolean

Alias
UMLS CUI [1]
C0229671
Blood
Description

Blood

Data type

boolean

Alias
UMLS CUI [1]
C0005767
Cells
Description

Cells

Data type

boolean

Alias
UMLS CUI [1]
C0007634
Stool
Description

Stool

Data type

boolean

Alias
UMLS CUI [1]
C0015733
Cerebrospinal fluid
Description

Cerebrospinal fluid

Data type

boolean

Alias
UMLS CUI [1]
C0007806
Other biomaterial
Description

Other biomaterial

Data type

boolean

Alias
UMLS CUI [1,1]
C0205394
UMLS CUI [1,2]
C2347026
Indicate other biomaterial
Description

Indicate other biomaterial

Data type

text

Alias
UMLS CUI [1,1]
C0205394
UMLS CUI [1,2]
C2347026
UMLS CUI [1,3]
C1521902
None
Description

No biomaterial available

Data type

boolean

Alias
UMLS CUI [1,1]
C0549184
UMLS CUI [1,2]
C2347026
UMLS CUI [1,3]
C0470187
Unknown
Description

Biomaterial available, unknown

Data type

boolean

Alias
UMLS CUI [1,1]
C2347026
UMLS CUI [1,2]
C0470187
UMLS CUI [1,3]
C0439673
Did the patient participate in an interventional clinical trial?
Description

Did the patient participate in an interventional clinical trial?

Alias
UMLS CUI-1