ID

42282

Description

Study Title: LEOSS: Lean European Open Survey on SARS-CoV-2 Infected Patients https://leoss.net Study Indication: COVID-19 Date: 19.03.2021 Published with permission by Prof. Dr. med. J.-J. Vehreschild. LEOSS, a multi-center cohort study, has been created to get more in-depth knowledge about the epidemiology and clinical course of patients infected with SARS-CoV-2. Initiated by the ESCMID Emerging Infections Task Force (EITaF) and the German Infectious Disease Society, and supported by all German Centers for Health Research (DZG), LEOSS has developed into an international network of contributors. Via an integrative research approach with anonymous recruitment and collection of routine data in an open science context, LEOSS is building a uniform clinical dataset and providing real-time analyses. For more information feel free to explore https://leoss.net/. This document is for the Diabetes mellitus sub-cohort. If a text field can't be filled out, note 'ND'.

Link

https://leoss.net

Keywords

Versions (4)
  1. 10/30/20 10/30/20 -
  2. 5/1/21 5/1/21 -
  3. 5/27/21 5/27/21 - Sarah Riepenhausen
  4. 6/28/21 6/28/21 -
Copyright Holder

LEOSS

Uploaded on

May 1, 2021

DOI

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License

Creative Commons BY 4.0
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LEOSS: Lean European Open Survey on SARS-CoV-2 Infected Patients

English

Diabetes mellitus sub-cohort

1 forms  
Diabetes mellitus details
Description

Diabetes mellitus details

Alias
UMLS CUI-1
C0011849
UMLS CUI-2
C1522508
Diabetes mellitus type
Description

DM type

Data type

integer

Alias
UMLS CUI [1]
C1320657
Specification of type 3 diabetes mellitus
Description

E.g. steroid induced, MODY, pancreatic, NODAT.

Data type

text

Alias
UMLS CUI [1,1]
C0011849
UMLS CUI [1,2]
C0441731
UMLS CUI [1,3]
C1521902
Duration of Diabetes mellitus
Description

Indicate duration of Diabetes mellitus before diagnosis of SARS-CoV-2.

Data type

integer

Alias
UMLS CUI [1,1]
C0011849
UMLS CUI [1,2]
C0449238
Hemoglobin A1c (HbA1c ) in blood
Description

Hemoglobin A1c (HbA1c ) in blood

Alias
UMLS CUI-1
C0474680
Hemoglobin A1c (HbA1c ) in blood
Description

Indicate values determined closest to the first positive PCR.

Data type

integer

Alias
UMLS CUI [1]
C0474680
C-peptide in blood
Description

C-peptide in blood

Alias
UMLS CUI-1
C0006558
UMLS CUI-2
C0005768
C-peptide in blood at admission day
Description

Indicate values determined at admission day.

Data type

integer

Measurement units
  • pmol/l
Alias
UMLS CUI [1,1]
C0006558
UMLS CUI [1,2]
C0005768
UMLS CUI [1,3]
C1302393
C-peptide in blood at admission day +1, sober
Description

Indicate values determined in blood at next morning after admission, sober.

Data type

integer

Measurement units
  • pmol/l
Alias
UMLS CUI [1,1]
C2208720
UMLS CUI [1,2]
C0005768
UMLS CUI [1,3]
C0332170
UMLS CUI [1,4]
C0687676
UMLS CUI [1,5]
C1302393
Glucose in blood
Description

Glucose in blood

Alias
UMLS CUI-1
C0392201
Blood glucose level at admission day
Description

Indicate values determined at admission day.

Data type

integer

Alias
UMLS CUI [1,1]
C1302393
UMLS CUI [1,2]
C0392201
Blood glucose level at admission day +1, fasting glucose
Description

Indicate values determined at next morning after admission, fasting glucose.

Data type

integer

Alias
UMLS CUI [1,1]
C0428568
UMLS CUI [1,2]
C0332170
UMLS CUI [1,3]
C0687676
UMLS CUI [1,4]
C1302393
C-peptide-to-Glucose Ratio (CGR) in blood
Description

C-peptide-to-Glucose Ratio (CGR) in blood

Alias
UMLS CUI-1
C0006558
UMLS CUI-2
C0017725
UMLS CUI-3
C0456603
UMLS CUI-4
C0005768
C-peptide-to-Glucose Ratio (CGR) at admission day
Description

Indicate values determined at admission day. C-peptide in (pmol/l); Glucose in (mg/dl).

Data type

integer

Alias
UMLS CUI [1,1]
C0006558
UMLS CUI [1,2]
C0017725
UMLS CUI [1,3]
C0456603
UMLS CUI [1,4]
C0005768
UMLS CUI [1,5]
C1302393
C-peptide-to-Glucose Ratio (CGR) at admission day +1, sober
Description

Indicate values determined at next morning after admission, sober. C-peptide in (pmol/l); Glucose in (mg/dl).

Data type

integer

Alias
UMLS CUI [1,1]
C0006558
UMLS CUI [1,2]
C0017725
UMLS CUI [1,3]
C0456603
UMLS CUI [1,4]
C0005768
UMLS CUI [1,5]
C0332170
UMLS CUI [1,6]
C0687676
UMLS CUI [1,7]
C1302393
UMLS CUI [1,8]
C0015663
Insulin level in blood
Description

Insulin level in blood

Alias
UMLS CUI-1
C0021641
UMLS CUI-2
C0005768
Insulin in blood at admission day
Description

Indicate values determined at admission day.

Data type

integer

Measurement units
  • mU/l
Alias
UMLS CUI [1,1]
C0021641
UMLS CUI [1,2]
C0005768
UMLS CUI [1,3]
C1302393
Insulin in blood at admission day +1, sober
Description

Indicate values determined at next morning after admission, sober.

Data type

integer

Measurement units
  • mU/l
Alias
UMLS CUI [1,1]
C0021641
UMLS CUI [1,2]
C0005768
UMLS CUI [1,3]
C0332170
UMLS CUI [1,4]
C0687676
UMLS CUI [1,5]
C1302393
UMLS CUI [1,6]
C0015663
Cortisol level in blood
Description

Cortisol level in blood

Alias
UMLS CUI-1
C0201968
UMLS CUI-2
C0005768
Cortisol level in blood at admission day
Description

Indicate values determined at admission day.

Data type

integer

Measurement units
  • µg/dl
Alias
UMLS CUI [1,1]
C0201968
UMLS CUI [1,2]
C0005768
UMLS CUI [1,3]
C1302393
Cortisol level in blood at admission day +1, sober
Description

Indicate values determined at next morning after admission, sober.

Data type

integer

Measurement units
  • µg/dl
Alias
UMLS CUI [1,1]
C0201968
UMLS CUI [1,2]
C0005768
UMLS CUI [1,3]
C0332170
UMLS CUI [1,4]
C0687676
UMLS CUI [1,5]
C1302393
UMLS CUI [1,6]
C0015663
Has insulin treatment been used before SARS-CoV-2 detection?
Description

Has insulin treatment been used before SARS-CoV-2 detection?

Alias
UMLS CUI-1
C0745343
UMLS CUI-2
C0332152
UMLS CUI-3
C5203676
UMLS CUI-4
C1511790
Insulin treatment
Description

Indicate insulin treatment before diagnosis of SARS-CoV-2.

Data type

integer

Alias
UMLS CUI [1,1]
C0745343
UMLS CUI [1,2]
C0332152
UMLS CUI [1,3]
C5203676
UMLS CUI [1,4]
C1511790
Has the insulin scheme been changed at the time of SARS-CoV-2 detection (+/- 48 h)?
Description

Has the insulin scheme been changed at the time of SARS-CoV-2 detection (+/- 48 h)?

Alias
UMLS CUI-1
C0745343
UMLS CUI-2
C4319952
UMLS CUI-3
C0687676
UMLS CUI-4
C5203676
UMLS CUI-5
C1511790
Change of insulin scheme
Description

Change of insulin scheme before or after diagnosis of SARS-CoV-2 (+/- 48 h).

Data type

integer

Alias
UMLS CUI [1,1]
C0745343
UMLS CUI [1,2]
C4319952
UMLS CUI [1,3]
C0687676
UMLS CUI [1,4]
C5203676
UMLS CUI [1,5]
C1511790
Which oral antidiabetic treatment has been used before SARS-CoV-2 detection?
Description

Which oral antidiabetic treatment has been used before SARS-CoV-2 detection?

Alias
UMLS CUI-1
C0359086
UMLS CUI-2
C0332152
UMLS CUI-3
C5203676
UMLS CUI-4
C1511790
Sulfonylureas
Description

Indicate treatment before diagnosis of SARS-CoV-2.

Data type

boolean

Alias
UMLS CUI [1]
C0038766
Metformin
Description

Indicate treatment before diagnosis of SARS-CoV-2.

Data type

boolean

Alias
UMLS CUI [1]
C0025598
GLP-1 analogues
Description

Indicate treatment before diagnosis of SARS-CoV-2.

Data type

boolean

Alias
UMLS CUI [1]
C3273809
DPP-4 blocker
Description

Indicate treatment before diagnosis of SARS-CoV-2.

Data type

boolean

Alias
UMLS CUI [1]
C1827106
SGLT-2 blocker
Description

Indicate treatment before diagnosis of SARS-CoV-2.

Data type

boolean

Alias
UMLS CUI [1]
C3273807
Other treatment
Description

Indicate treatment before diagnosis of SARS-CoV-2.

Data type

boolean

Alias
UMLS CUI [1,1]
C0205394
UMLS CUI [1,2]
C0359086
Name of other oral antidiabetic treatment
Description

Indicate other oral antidiabetic treatment

Data type

text

Alias
UMLS CUI [1,1]
C0205394
UMLS CUI [1,2]
C0359086
UMLS CUI [1,3]
C1521902
None
Description

Indicate treatment before diagnosis of SARS-CoV-2.

Data type

boolean

Alias
UMLS CUI [1,1]
C0549184
UMLS CUI [1,2]
C0359086
Unknown
Description

Oral antidiabetic treatment, unknown

Data type

boolean

Alias
UMLS CUI [1,1]
C0359086
UMLS CUI [1,2]
C0439673
Is data entry for this section finished?
Description

Is data entry for this section finished?

Alias
UMLS CUI-1
C4684556
UMLS CUI-2
C1828479
UMLS CUI-3
C0205197
Is data entry for this section finished?
Description

Is data entry for this section finished?

Data type

boolean

Alias
UMLS CUI [1,1]
C4684556
UMLS CUI [1,2]
C1828479
UMLS CUI [1,3]
C0205197
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Similar models

Diabetes mellitus sub-cohort

1 forms
Name
Type
Description | Question | Decode (Coded Value)
Data type
Alias
Item Group
Diabetes mellitus details
C0011849 (UMLS CUI-1)
C1522508 (UMLS CUI-2)
Item
Diabetes mellitus type
integer
C1320657 (UMLS CUI [1])
Diabetes type
Code List
Diabetes mellitus type
CL Item
Type 1 (1)
CL Item
Type 2 (2)
CL Item
Type 3 (e.g steroid induced, MODY, pancreatic, NODAT) (3)
CL Item
Unknown (4)
Specification of type 3 diabetes mellitus
Item
Specification of type 3 diabetes mellitus
text
C0011849 (UMLS CUI [1,1])
C0441731 (UMLS CUI [1,2])
C1521902 (UMLS CUI [1,3])
Item
Duration of Diabetes mellitus
integer
C0011849 (UMLS CUI [1,1])
C0449238 (UMLS CUI [1,2])
Duration of Diabetes
Code List
Duration of Diabetes mellitus
CL Item
<1 year (1)
CL Item
1-10 years (2)
CL Item
> 10 years (3)
CL Item
Unknown (4)
Item Group
Hemoglobin A1c (HbA1c ) in blood
C0474680 (UMLS CUI-1)
Item
Hemoglobin A1c (HbA1c ) in blood
integer
C0474680 (UMLS CUI [1])
Hemoglobin A1c (HbA1c ) in blood
Code List
Hemoglobin A1c (HbA1c ) in blood
CL Item
<6.4% (1)
CL Item
6.4% - 8% (2)
CL Item
8.1% - 10% (3)
CL Item
10.1 - 12 % (4)
CL Item
Unknown (5)
Item Group
C-peptide in blood
C0006558 (UMLS CUI-1)
C0005768 (UMLS CUI-2)
Item
C-peptide in blood at admission day
integer
C0006558 (UMLS CUI [1,1])
C0005768 (UMLS CUI [1,2])
C1302393 (UMLS CUI [1,3])
C-peptide admission
Code List
C-peptide in blood at admission day
CL Item
< 20 pmol/l (1)
CL Item
20-80 pmol/l (2)
CL Item
81-200 pmol/l (3)
CL Item
> 200 pmol/l (4)
CL Item
Not done (5)
CL Item
Unknown (6)
Item
C-peptide in blood at admission day +1, sober
integer
C2208720 (UMLS CUI [1,1])
C0005768 (UMLS CUI [1,2])
C0332170 (UMLS CUI [1,3])
C0687676 (UMLS CUI [1,4])
C1302393 (UMLS CUI [1,5])
C-peptide sober
Code List
C-peptide in blood at admission day +1, sober
CL Item
< 20 pmol/l (1)
CL Item
20-80 pmol/l (2)
CL Item
81-200 pmol/l (3)
CL Item
> 200 pmol/l (4)
CL Item
Not done (5)
CL Item
Unknown (6)
Item Group
Glucose in blood
C0392201 (UMLS CUI-1)
Item
Blood glucose level at admission day
integer
C1302393 (UMLS CUI [1,1])
C0392201 (UMLS CUI [1,2])
Blood glucose level: Admission day
Code List
Blood glucose level at admission day
CL Item
<100 mg/dl (1)
CL Item
100-126 mg/dl (2)
CL Item
127-200 mg/dl (3)
CL Item
>200 mg/dl (4)
CL Item
Unknown (5)
Item
Blood glucose level at admission day +1, fasting glucose
integer
C0428568 (UMLS CUI [1,1])
C0332170 (UMLS CUI [1,2])
C0687676 (UMLS CUI [1,3])
C1302393 (UMLS CUI [1,4])
Blood glucose level: Admission day +1 fasting glucose
Code List
Blood glucose level at admission day +1, fasting glucose
CL Item
<100 mg/dl (1)
CL Item
100-126 mg/dl (2)
CL Item
127-200 mg/dl (3)
CL Item
>200 mg/dl (4)
CL Item
Unknown (5)
Item Group
C-peptide-to-Glucose Ratio (CGR) in blood
C0006558 (UMLS CUI-1)
C0017725 (UMLS CUI-2)
C0456603 (UMLS CUI-3)
C0005768 (UMLS CUI-4)
Item
C-peptide-to-Glucose Ratio (CGR) at admission day
integer
C0006558 (UMLS CUI [1,1])
C0017725 (UMLS CUI [1,2])
C0456603 (UMLS CUI [1,3])
C0005768 (UMLS CUI [1,4])
C1302393 (UMLS CUI [1,5])
CGR: Admission day
Code List
C-peptide-to-Glucose Ratio (CGR) at admission day
CL Item
<2 (1)
CL Item
2 - 5 (2)
CL Item
>5 (3)
CL Item
Unknown (4)
Item
C-peptide-to-Glucose Ratio (CGR) at admission day +1, sober
integer
C0006558 (UMLS CUI [1,1])
C0017725 (UMLS CUI [1,2])
C0456603 (UMLS CUI [1,3])
C0005768 (UMLS CUI [1,4])
C0332170 (UMLS CUI [1,5])
C0687676 (UMLS CUI [1,6])
C1302393 (UMLS CUI [1,7])
C0015663 (UMLS CUI [1,8])
CGR: Admission day
Code List
C-peptide-to-Glucose Ratio (CGR) at admission day +1, sober
CL Item
<2 (1)
CL Item
2 - 5 (2)
CL Item
>5 (3)
CL Item
Unknown (4)
Item Group
Insulin level in blood
C0021641 (UMLS CUI-1)
C0005768 (UMLS CUI-2)
Item
Insulin in blood at admission day
integer
C0021641 (UMLS CUI [1,1])
C0005768 (UMLS CUI [1,2])
C1302393 (UMLS CUI [1,3])
Insulin Admission
Code List
Insulin in blood at admission day
CL Item
< 3 mU/l (1)
CL Item
3-20 mU/l (2)
CL Item
21-200 mU/l (3)
CL Item
> 200 mU/l  (4)
CL Item
Not done (5)
CL Item
Unknown (6)
Item
Insulin in blood at admission day +1, sober
integer
C0021641 (UMLS CUI [1,1])
C0005768 (UMLS CUI [1,2])
C0332170 (UMLS CUI [1,3])
C0687676 (UMLS CUI [1,4])
C1302393 (UMLS CUI [1,5])
C0015663 (UMLS CUI [1,6])
Insulin admission +1
Code List
Insulin in blood at admission day +1, sober
CL Item
< 3 mU/l (1)
CL Item
3-20 mU/l (2)
CL Item
21-200 mU/l (3)
CL Item
> 200 mU/l  (4)
CL Item
Not done (5)
CL Item
Unknown (6)
Item Group
Cortisol level in blood
C0201968 (UMLS CUI-1)
C0005768 (UMLS CUI-2)
Item
Cortisol level in blood at admission day
integer
C0201968 (UMLS CUI [1,1])
C0005768 (UMLS CUI [1,2])
C1302393 (UMLS CUI [1,3])
Cortisol admission
Code List
Cortisol level in blood at admission day
CL Item
< 2 µg/dl (1)
CL Item
2-10 µg/dl (2)
CL Item
11-20 µg/dl (3)
CL Item
> 20 µg/dl (4)
CL Item
Not done (5)
CL Item
Unknown (6)
Item
Cortisol level in blood at admission day +1, sober
integer
C0201968 (UMLS CUI [1,1])
C0005768 (UMLS CUI [1,2])
C0332170 (UMLS CUI [1,3])
C0687676 (UMLS CUI [1,4])
C1302393 (UMLS CUI [1,5])
C0015663 (UMLS CUI [1,6])
Cortisol admission +1
Code List
Cortisol level in blood at admission day +1, sober
CL Item
< 2 µg/dl (1)
CL Item
2-10 µg/dl (2)
CL Item
11-20 µg/dl (3)
CL Item
> 20 µg/dl (4)
CL Item
Not done (5)
CL Item
Unknown (6)
Item Group
Has insulin treatment been used before SARS-CoV-2 detection?
C0745343 (UMLS CUI-1)
C0332152 (UMLS CUI-2)
C5203676 (UMLS CUI-3)
C1511790 (UMLS CUI-4)
Item
Insulin treatment
integer
C0745343 (UMLS CUI [1,1])
C0332152 (UMLS CUI [1,2])
C5203676 (UMLS CUI [1,3])
C1511790 (UMLS CUI [1,4])
Has insulin treatment been used before SARS-CoV-2 detection?
Code List
Insulin treatment
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item Group
Has the insulin scheme been changed at the time of SARS-CoV-2 detection (+/- 48 h)?
C0745343 (UMLS CUI-1)
C4319952 (UMLS CUI-2)
C0687676 (UMLS CUI-3)
C5203676 (UMLS CUI-4)
C1511790 (UMLS CUI-5)
Item
Change of insulin scheme
integer
C0745343 (UMLS CUI [1,1])
C4319952 (UMLS CUI [1,2])
C0687676 (UMLS CUI [1,3])
C5203676 (UMLS CUI [1,4])
C1511790 (UMLS CUI [1,5])
Has the insulin scheme been changed at the time of SARS-CoV-2 detection (+/- 48 h)?
Code List
Change of insulin scheme
CL Item
Yes (1)
CL Item
No (2)
CL Item
Unknown (3)
Item Group
Which oral antidiabetic treatment has been used before SARS-CoV-2 detection?
C0359086 (UMLS CUI-1)
C0332152 (UMLS CUI-2)
C5203676 (UMLS CUI-3)
C1511790 (UMLS CUI-4)
Sulfonylureas
Item
Sulfonylureas
boolean
C0038766 (UMLS CUI [1])
Metformin
Item
Metformin
boolean
C0025598 (UMLS CUI [1])
GLP-1 analogues
Item
GLP-1 analogues
boolean
C3273809 (UMLS CUI [1])
DPP-4 blocker
Item
DPP-4 blocker
boolean
C1827106 (UMLS CUI [1])
SGLT-2 blocker
Item
SGLT-2 blocker
boolean
C3273807 (UMLS CUI [1])
Other oral antidiabetic treatment
Item
Other treatment
boolean
C0205394 (UMLS CUI [1,1])
C0359086 (UMLS CUI [1,2])
Indicate other oral antidiabetic treatment
Item
Name of other oral antidiabetic treatment
text
C0205394 (UMLS CUI [1,1])
C0359086 (UMLS CUI [1,2])
C1521902 (UMLS CUI [1,3])
No oral antidiabetic treatment
Item
None
boolean
C0549184 (UMLS CUI [1,1])
C0359086 (UMLS CUI [1,2])
Oral antidiabetic treatment, unknown
Item
Unknown
boolean
C0359086 (UMLS CUI [1,1])
C0439673 (UMLS CUI [1,2])
Item Group
Is data entry for this section finished?
C4684556 (UMLS CUI-1)
C1828479 (UMLS CUI-2)
C0205197 (UMLS CUI-3)
Is data entry for this section finished?
Item
Is data entry for this section finished?
boolean
C4684556 (UMLS CUI [1,1])
C1828479 (UMLS CUI [1,2])
C0205197 (UMLS CUI [1,3])
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