ID

41278

Beskrivning

The primary focus of this first time in human (FTIH) study was to evaluate the safety and tolerability of GSK1292263 and to estimate GSK1292263 pharmacokinetic (PK) parameters and pharmacodynamic (PD) effects in healthy volunteers. Subject: FTIH, oral, safety, tolerability, pharmacokinetics, glucose, pharmacodynamics, male, female, gastric emptying Indication Studied: Type 2 Diabetes Mellitis Study ID: 111596 Clinical Study ID: 111596 Study Title: A study in healthy volunteers of single doses of orally administered GSK1292263 to investigate the safety, tolerability, pharmacokinetics and pharmacodynamics of the compound alone and when co-administered with sitagliptin Patient Level Data: Study Listed on ClinicalStudyDataRequest.com Clinicaltrials.gov Identifier: NCT00783549 Sponsor: GlaxoSmithKline Collaborators: N/A Phase: Phase 1 Study Recruitment Status: Completed Generic Name: GSK1292263, Sitagliptin Trade Name: N/A Study Indication: Dyslipidaemias

Nyckelord

Versioner (1)
  1. 2020-08-10 2020-08-10 -
Rättsinnehavare

GlaxoSmithKline

Uppladdad den

10 augusti 2020

DOI

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Licens

Creative Commons BY-NC 4.0
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A study in healthy volunteers of single doses of orally administered GSK1292263 to investigate the safety, tolerability, pharmacokinetics and pharmacodynamics of the compound alone and when co-administered with sitagliptin

Engelsk

Summary Telemetry Abnormalities V12 6-DF

1 Formulär  
RECORD CLINICALLY SIGNIFICANT ABNORMALITIES BELOW
Beskrivning

RECORD CLINICALLY SIGNIFICANT ABNORMALITIES BELOW

Alias
UMLS CUI-1
C0039451
UMLS CUI-2
C1704258
No abnormalities
Beskrivning

No Telemetry Abnormalities

Datatyp

boolean

Alias
UMLS CUI [1,1]
C0039451
UMLS CUI [1,2]
C0438154
Sinus bradycardia (50-59 beats/min)
Beskrivning

Sinus bradycardia (50-59 beats/min)

Datatyp

boolean

Alias
UMLS CUI [1,1]
C0085610
UMLS CUI [1,2]
C0018810
Sinus bradycardia (40-49 beats/min)
Beskrivning

Sinus bradycardia (40-49 beats/min)

Datatyp

boolean

Alias
UMLS CUI [1,1]
C0085610
UMLS CUI [1,2]
C0018810
Sinus bradycardia (30-39 beats/min)
Beskrivning

Sinus bradycardia (30-39 beats/min)

Datatyp

boolean

Alias
UMLS CUI [1,1]
C0085610
UMLS CUI [1,2]
C0018810
Sinus bradycardia (<30 beats/min)
Beskrivning

Sinus bradycardia (<30 beats/min)

Datatyp

boolean

Alias
UMLS CUI [1,1]
C0085610
UMLS CUI [1,2]
C0018810
Sinus pause
Beskrivning

Sinus pause

Datatyp

boolean

Alias
UMLS CUI [1]
C1955864
Sinus tachycardia (heart rate > 100 beats/min)
Beskrivning

Sinus tachycardia

Datatyp

boolean

Alias
UMLS CUI [1,1]
C0039239
UMLS CUI [1,2]
C0018810
Ectopic supraventricular beats
Beskrivning

Ectopic supraventricular beats

Datatyp

boolean

Alias
UMLS CUI [1]
C0033036
Ectopic supraventricular rhythm
Beskrivning

Ectopic supraventricular rhythm

Datatyp

boolean

Alias
UMLS CUI [1]
C2348376
Wandering atrial pacemaker
Beskrivning

Wandering atrial pacemaker

Datatyp

boolean

Alias
UMLS CUI [1]
C1321523
Multifocal atrial tachycardia (wandering atrial pacemaker with heart rate > 100 beats/min)
Beskrivning

Multifocal atrial tachycardia

Datatyp

boolean

Alias
UMLS CUI [1,1]
C0221158
UMLS CUI [1,2]
C0018810
Non-sustained supraventricular tachycardia (>100 beats/min, 3-30 beats)
Beskrivning

Non-sustained supraventricular tachycardia

Datatyp

boolean

Alias
UMLS CUI [1,1]
C0039240
UMLS CUI [1,2]
C0018810
UMLS CUI [1,3]
C0205374
Sustained supraventricular tachycardia, (>100 beats/min, >30 beats)
Beskrivning

Sustained supraventricular tachycardia

Datatyp

boolean

Alias
UMLS CUI [1,1]
C0039240
UMLS CUI [1,2]
C0443318
UMLS CUI [1,3]
C0018810
Atrial flutter
Beskrivning

Atrial flutter

Datatyp

boolean

Alias
UMLS CUI [1]
C0004239
Atrial fibrillation
Beskrivning

Atrial fibrillation

Datatyp

boolean

Alias
UMLS CUI [1]
C0004238
Junctional rhythm (<= 100 beats/min, defined by narrow QRS complex)
Beskrivning

Junctional rhythm (<= 100 beats/min, defined by narrow QRS complex)

Datatyp

boolean

Alias
UMLS CUI [1,1]
C0232208
UMLS CUI [1,2]
C0018810
Junctional tachycardia (heart rate > 100 beats/min)
Beskrivning

Junctional tachycardia

Datatyp

boolean

Alias
UMLS CUI [1,1]
C0039235
UMLS CUI [1,2]
C0018810
Ventricular premature depolarisation
Beskrivning

Ventricular premature depolarisation

Datatyp

boolean

Alias
UMLS CUI [1]
C0151636
Ventricular couplets
Beskrivning

Ventricular couplets

Datatyp

boolean

Alias
UMLS CUI [1]
C0429001
Bigeminy
Beskrivning

Bigeminy

Datatyp

boolean

Alias
UMLS CUI [1]
C0262662
Trigeminy
Beskrivning

Trigeminy

Datatyp

boolean

Alias
UMLS CUI [1]
C0428999
Electrical alternans
Beskrivning

Electrical alternans

Datatyp

boolean

Alias
UMLS CUI [1]
C1142551
R on T phenomenon
Beskrivning

R on T phenomenon

Datatyp

boolean

Alias
UMLS CUI [1]
C0877658
Ventricular fibrillation
Beskrivning

Ventricular fibrillation

Datatyp

boolean

Alias
UMLS CUI [1]
C0042510
ldioventricular rhythm (<= 100 beats/min, defined by wide QRS complex)
Beskrivning

ldioventricular rhythm

Datatyp

boolean

Alias
UMLS CUI [1]
C0700363
Non-sustained ventricular tachycardia (>100 beats/min, 3-30 beats)
Beskrivning

Non-sustained ventricular tachycardia

Datatyp

boolean

Alias
UMLS CUI [1]
C0750194
Sustained ventricular tachycardia (<100 beats/min, >30 beats)
Beskrivning

Sustained ventricular tachycardia

Datatyp

boolean

Alias
UMLS CUI [1]
C0750197
Wide QRS tachycardia (diagnosis unknown)
Beskrivning

Wide QRS tachycardia

Datatyp

boolean

Alias
UMLS CUI [1,1]
C0344429
UMLS CUI [1,2]
C0439673
UMLS CUI [1,3]
C0011900
Monomorphic non-sustained ventricular tachycardia (>100 beats/min, 3-30 beats)
Beskrivning

Monomorphic non-sustained ventricular tachycardia (>100 beats/min, 3-30 beats)

Datatyp

boolean

Alias
UMLS CUI [1,1]
C0344431
UMLS CUI [1,2]
C0750194
Monomorphic sustained ventricular tachycardia (> 100 beats/min, >30 beats)
Beskrivning

Monomorphic sustained ventricular tachycardia (> 100 beats/min, >30 beats)

Datatyp

boolean

Alias
UMLS CUI [1,1]
C0344431
UMLS CUI [1,2]
C0750197
Polymorphic non-sustained ventricular tachycardia (>100 beats/min, 3-30 beats)
Beskrivning

Polymorphic non-sustained ventricular tachycardia (>100 beats/min, 3-30 beats)

Datatyp

boolean

Alias
UMLS CUI [1,1]
C0344432
UMLS CUI [1,2]
C0750194
Polymorphic sustained ventricular tachycardia (>100 beats/min, >30 beats)
Beskrivning

Polymorphic sustained ventricular tachycardia (>100 beats/min, >30 beats)

Datatyp

boolean

Alias
UMLS CUI [1,1]
C0344432
UMLS CUI [1,2]
C0750197
Torsades de Pointes (TdP)
Beskrivning

Torsades de Pointes

Datatyp

boolean

Alias
UMLS CUI [1]
C0040479
Pacemaker
Beskrivning

Artificial Pacemaker

Datatyp

boolean

Alias
UMLS CUI [1]
C0030163
First degree AV block (PR interval> 200msec)
Beskrivning

First degree AV block

Datatyp

boolean

Alias
UMLS CUI [1]
C0085614
Short PR interval
Beskrivning

Short PR interval

Datatyp

boolean

Alias
UMLS CUI [1]
C0520878
Second degree AV block (Mobitz type 1)
Beskrivning

Second degree AV block (Mobitz type 1)

Datatyp

boolean

Alias
UMLS CUI [1]
C0264907
Second degree AV block (Mobitz type 2)
Beskrivning

Second degree AV block (Mobitz type 2)

Datatyp

boolean

Alias
UMLS CUI [1]
C0155700
2: 1 AV block
Beskrivning

2: 1 AV block

Datatyp

boolean

Alias
UMLS CUI [1]
C2346542
Third degree AV block
Beskrivning

Third degree AV block

Datatyp

boolean

Alias
UMLS CUI [1]
C0151517
Left axis deviation (QRS axis more negative than -30 degrees)
Beskrivning

Left axis deviation

Datatyp

boolean

Alias
UMLS CUI [1]
C0232297
Right axis deviation (QRS axis more positive than +110 degrees)
Beskrivning

Right axis deviation

Datatyp

boolean

Alias
UMLS CUI [1]
C0232296
Incomplete right bundle branch block
Beskrivning

Incomplete right bundle branch block

Datatyp

boolean

Alias
UMLS CUI [1]
C0262525
Incomplete left bundle branch block
Beskrivning

Incomplete left bundle branch block

Datatyp

boolean

Alias
UMLS CUI [1]
C0281878
Right bundle branch block
Beskrivning

Right bundle branch block

Datatyp

boolean

Alias
UMLS CUI [1]
C0085615
Left anterior hemiblock
Beskrivning

Left anterior hemiblock

Datatyp

boolean

Alias
UMLS CUI [1]
C0264912
Left posterior hemiblock
Beskrivning

Left posterior hemiblock

Datatyp

boolean

Alias
UMLS CUI [1]
C0264913
Left bundle branch block
Beskrivning

Left bundle branch block

Datatyp

boolean

Alias
UMLS CUI [1]
C0023211
Bifascicular block
Beskrivning

Bifascicular block

Datatyp

boolean

Alias
UMLS CUI [1]
C0264914
Non-specific intraventricular conduction delay (QRS >= 120 msec)
Beskrivning

Non-specific intraventricular conduction delay

Datatyp

boolean

Alias
UMLS CUI [1]
C3697597
Accessory pathway (Wolff-Parkinson White, Lown-Ganong-Levine)
Beskrivning

Accessory pathway in Wolff-Parkinson White/Lown-Ganong-Levine Syndrome

Datatyp

boolean

Alias
UMLS CUI [1,1]
C1963785
UMLS CUI [1,2]
C0043202
UMLS CUI [2,1]
C1963785
UMLS CUI [2,2]
C0024054
QTc prolongation >=500msec
Beskrivning

QTc prolongation

Datatyp

boolean

Alias
UMLS CUI [1]
C0855333
UMLS CUI [2]
C0489625
AV dissociation
Beskrivning

AV dissociation

Datatyp

boolean

Alias
UMLS CUI [1]
C0004331
Myocardial infarction, old
Beskrivning

Myocardial infarction, old

Datatyp

boolean

Alias
UMLS CUI [1]
C0155668
Myocardial infarction, Non Q-wave
Beskrivning

Myocardial infarction, Non Q-wave

Datatyp

boolean

Alias
UMLS CUI [1]
C0542269
Non-specific ST-T changes
Beskrivning

Non-specific ST-T changes

Datatyp

boolean

Alias
UMLS CUI [1]
C1112720
J point elevation
Beskrivning

J point elevation

Datatyp

boolean

Alias
UMLS CUI [1]
C2346597
ST elevation
Beskrivning

ST elevation

Datatyp

boolean

Alias
UMLS CUI [1]
C0520886
ST depression
Beskrivning

ST depression

Datatyp

boolean

Alias
UMLS CUI [1]
C0520887
ST segment abnormality
Beskrivning

ST segment abnormality

Datatyp

boolean

Alias
UMLS CUI [1]
C2348120
U waves
Beskrivning

U waves

Datatyp

boolean

Alias
UMLS CUI [1]
C0232333
T wave inversion
Beskrivning

T wave inversion

Datatyp

boolean

Alias
UMLS CUI [1]
C0520888
T wave peaked
Beskrivning

T wave peaked

Datatyp

boolean

Alias
UMLS CUI [1]
C0239242
T waves biphasic
Beskrivning

T waves biphasic

Datatyp

boolean

Alias
UMLS CUI [1]
C2348639
T waves flat
Beskrivning

T waves flat

Datatyp

boolean

Alias
UMLS CUI [1]
C2215959
Notched T-waves
Beskrivning

Notched T-waves

Datatyp

boolean

Alias
UMLS CUI [1]
C2347367
Low QRS voltage
Beskrivning

Low QRS voltage

Datatyp

boolean

Alias
UMLS CUI [1]
C2349945
T wave abnormality
Beskrivning

T wave abnormality

Datatyp

boolean

Alias
UMLS CUI [1]
C0438167
Other abnormal rhythm
Beskrivning

If yes, enter comment

Datatyp

boolean

Alias
UMLS CUI [1,1]
C0205394
UMLS CUI [1,2]
C0199556
UMLS CUI [1,3]
C0205161
Comment
Beskrivning

12 lead ECG, Abnormality, Electrocardiogram: Rhythm, Comment

Datatyp

text

Alias
UMLS CUI [1,1]
C0430456
UMLS CUI [1,2]
C1704258
UMLS CUI [1,3]
C0199556
UMLS CUI [1,4]
C0947611
Other morphology
Beskrivning

If yes, enter comment

Datatyp

boolean

Alias
UMLS CUI [1,1]
C0205394
UMLS CUI [1,2]
C0332437
Comment
Beskrivning

12 lead ECG, Abnormality, electrocardiogram: P wave shifting morphology, Comment; 12 lead ECG, Abnormality, Electrocardiogram QRS complex, Comment

Datatyp

text

Alias
UMLS CUI [1,1]
C0430456
UMLS CUI [1,2]
C1704258
UMLS CUI [1,3]
C2216025
UMLS CUI [1,4]
C0947611
UMLS CUI [2,1]
C0430456
UMLS CUI [2,2]
C1704258
UMLS CUI [2,3]
C0429098
UMLS CUI [2,4]
C0947611
Other conduction
Beskrivning

If yes, enter comment

Datatyp

boolean

Alias
UMLS CUI [1]
C0340494
Comment
Beskrivning

12 lead ECG, Abnormality, Cardiac Conduction, Comment

Datatyp

text

Alias
UMLS CUI [1,1]
C0430456
UMLS CUI [1,2]
C1704258
UMLS CUI [1,3]
C0232217
UMLS CUI [1,4]
C0947611
Other myocardial infarction
Beskrivning

If yes, enter comment

Datatyp

boolean

Alias
UMLS CUI [1,1]
C0205394
UMLS CUI [1,2]
C0027051
Comment
Beskrivning

12 lead ECG, Abnormality, Myocardial Infarction, Comment

Datatyp

text

Alias
UMLS CUI [1,1]
C0430456
UMLS CUI [1,2]
C1704258
UMLS CUI [1,3]
C0027051
UMLS CUI [1,4]
C0947611
Other depolarisation/repolarisation
Beskrivning

If yes, enter comment

Datatyp

boolean

Alias
UMLS CUI [1,1]
C0205394
UMLS CUI [1,2]
C0205161
UMLS CUI [1,3]
C2746082
UMLS CUI [2,1]
C0948857
UMLS CUI [2,2]
C0205394
Comment
Beskrivning

12 lead ECG, Abnormality, Ventricular Depolarization [PE], Comment; 12 lead ECG, Abnormality, Electrocardiogram repolarisation abnormality, Comment

Datatyp

text

Alias
UMLS CUI [1,1]
C0430456
UMLS CUI [1,2]
C1704258
UMLS CUI [1,3]
C1331539
UMLS CUI [1,4]
C0947611
UMLS CUI [2,1]
C0430456
UMLS CUI [2,2]
C1704258
UMLS CUI [2,3]
C0948857
UMLS CUI [2,4]
C0947611
Other abnormalities/Cardiologist Comments
Beskrivning

12 lead ECG, Abnormality, Other | Cardiologists, comment

Datatyp

boolean

Alias
UMLS CUI [1,1]
C0430456
UMLS CUI [1,2]
C1704258
UMLS CUI [1,3]
C0205394
UMLS CUI [2,1]
C0175906
UMLS CUI [2,2]
C0947611
Comment
Beskrivning

12 lead ECG, Abnormality, Other, Comment | Cardiologists, Comment

Datatyp

text

Alias
UMLS CUI [1,1]
C0430456
UMLS CUI [1,2]
C1704258
UMLS CUI [1,3]
C0205394
UMLS CUI [1,4]
C0947611
UMLS CUI [2,1]
C0175906
UMLS CUI [2,2]
C0947611
Tillbaka till toppen

Similar models

Summary Telemetry Abnormalities V12 6-DF

1 Formulär
Name
Typ
Description | Question | Decode (Coded Value)
Datatyp
Alias
Item Group
RECORD CLINICALLY SIGNIFICANT ABNORMALITIES BELOW
C0039451 (UMLS CUI-1)
C1704258 (UMLS CUI-2)
No Telemetry Abnormalities
Item
No abnormalities
boolean
C0039451 (UMLS CUI [1,1])
C0438154 (UMLS CUI [1,2])
Sinus bradycardia (50-59 beats/min)
Item
Sinus bradycardia (50-59 beats/min)
boolean
C0085610 (UMLS CUI [1,1])
C0018810 (UMLS CUI [1,2])
Sinus bradycardia (40-49 beats/min)
Item
Sinus bradycardia (40-49 beats/min)
boolean
C0085610 (UMLS CUI [1,1])
C0018810 (UMLS CUI [1,2])
Sinus bradycardia (30-39 beats/min)
Item
Sinus bradycardia (30-39 beats/min)
boolean
C0085610 (UMLS CUI [1,1])
C0018810 (UMLS CUI [1,2])
Sinus bradycardia (<30 beats/min)
Item
Sinus bradycardia (<30 beats/min)
boolean
C0085610 (UMLS CUI [1,1])
C0018810 (UMLS CUI [1,2])
Sinus pause
Item
Sinus pause
boolean
C1955864 (UMLS CUI [1])
Sinus tachycardia
Item
Sinus tachycardia (heart rate > 100 beats/min)
boolean
C0039239 (UMLS CUI [1,1])
C0018810 (UMLS CUI [1,2])
Ectopic supraventricular beats
Item
Ectopic supraventricular beats
boolean
C0033036 (UMLS CUI [1])
Ectopic supraventricular rhythm
Item
Ectopic supraventricular rhythm
boolean
C2348376 (UMLS CUI [1])
Wandering atrial pacemaker
Item
Wandering atrial pacemaker
boolean
C1321523 (UMLS CUI [1])
Multifocal atrial tachycardia
Item
Multifocal atrial tachycardia (wandering atrial pacemaker with heart rate > 100 beats/min)
boolean
C0221158 (UMLS CUI [1,1])
C0018810 (UMLS CUI [1,2])
Non-sustained supraventricular tachycardia
Item
Non-sustained supraventricular tachycardia (>100 beats/min, 3-30 beats)
boolean
C0039240 (UMLS CUI [1,1])
C0018810 (UMLS CUI [1,2])
C0205374 (UMLS CUI [1,3])
Sustained supraventricular tachycardia
Item
Sustained supraventricular tachycardia, (>100 beats/min, >30 beats)
boolean
C0039240 (UMLS CUI [1,1])
C0443318 (UMLS CUI [1,2])
C0018810 (UMLS CUI [1,3])
Atrial flutter
Item
Atrial flutter
boolean
C0004239 (UMLS CUI [1])
Atrial fibrillation
Item
Atrial fibrillation
boolean
C0004238 (UMLS CUI [1])
Junctional rhythm (<= 100 beats/min, defined by narrow QRS complex)
Item
Junctional rhythm (<= 100 beats/min, defined by narrow QRS complex)
boolean
C0232208 (UMLS CUI [1,1])
C0018810 (UMLS CUI [1,2])
Junctional tachycardia
Item
Junctional tachycardia (heart rate > 100 beats/min)
boolean
C0039235 (UMLS CUI [1,1])
C0018810 (UMLS CUI [1,2])
Ventricular premature depolarisation
Item
Ventricular premature depolarisation
boolean
C0151636 (UMLS CUI [1])
Ventricular couplets
Item
Ventricular couplets
boolean
C0429001 (UMLS CUI [1])
Bigeminy
Item
Bigeminy
boolean
C0262662 (UMLS CUI [1])
Trigeminy
Item
Trigeminy
boolean
C0428999 (UMLS CUI [1])
Electrical alternans
Item
Electrical alternans
boolean
C1142551 (UMLS CUI [1])
R on T phenomenon
Item
R on T phenomenon
boolean
C0877658 (UMLS CUI [1])
Ventricular fibrillation
Item
Ventricular fibrillation
boolean
C0042510 (UMLS CUI [1])
ldioventricular rhythm
Item
ldioventricular rhythm (<= 100 beats/min, defined by wide QRS complex)
boolean
C0700363 (UMLS CUI [1])
Non-sustained ventricular tachycardia
Item
Non-sustained ventricular tachycardia (>100 beats/min, 3-30 beats)
boolean
C0750194 (UMLS CUI [1])
Sustained ventricular tachycardia
Item
Sustained ventricular tachycardia (<100 beats/min, >30 beats)
boolean
C0750197 (UMLS CUI [1])
Wide QRS tachycardia
Item
Wide QRS tachycardia (diagnosis unknown)
boolean
C0344429 (UMLS CUI [1,1])
C0439673 (UMLS CUI [1,2])
C0011900 (UMLS CUI [1,3])
Monomorphic non-sustained ventricular tachycardia (>100 beats/min, 3-30 beats)
Item
Monomorphic non-sustained ventricular tachycardia (>100 beats/min, 3-30 beats)
boolean
C0344431 (UMLS CUI [1,1])
C0750194 (UMLS CUI [1,2])
Monomorphic sustained ventricular tachycardia (> 100 beats/min, >30 beats)
Item
Monomorphic sustained ventricular tachycardia (> 100 beats/min, >30 beats)
boolean
C0344431 (UMLS CUI [1,1])
C0750197 (UMLS CUI [1,2])
Polymorphic non-sustained ventricular tachycardia (>100 beats/min, 3-30 beats)
Item
Polymorphic non-sustained ventricular tachycardia (>100 beats/min, 3-30 beats)
boolean
C0344432 (UMLS CUI [1,1])
C0750194 (UMLS CUI [1,2])
Polymorphic sustained ventricular tachycardia (>100 beats/min, >30 beats)
Item
Polymorphic sustained ventricular tachycardia (>100 beats/min, >30 beats)
boolean
C0344432 (UMLS CUI [1,1])
C0750197 (UMLS CUI [1,2])
Torsades de Pointes
Item
Torsades de Pointes (TdP)
boolean
C0040479 (UMLS CUI [1])
Artificial Pacemaker
Item
Pacemaker
boolean
C0030163 (UMLS CUI [1])
First degree AV block
Item
First degree AV block (PR interval> 200msec)
boolean
C0085614 (UMLS CUI [1])
Short PR interval
Item
Short PR interval
boolean
C0520878 (UMLS CUI [1])
Second degree AV block (Mobitz type 1)
Item
Second degree AV block (Mobitz type 1)
boolean
C0264907 (UMLS CUI [1])
Second degree AV block (Mobitz type 2)
Item
Second degree AV block (Mobitz type 2)
boolean
C0155700 (UMLS CUI [1])
2: 1 AV block
Item
2: 1 AV block
boolean
C2346542 (UMLS CUI [1])
Third degree AV block
Item
Third degree AV block
boolean
C0151517 (UMLS CUI [1])
Left axis deviation
Item
Left axis deviation (QRS axis more negative than -30 degrees)
boolean
C0232297 (UMLS CUI [1])
Right axis deviation
Item
Right axis deviation (QRS axis more positive than +110 degrees)
boolean
C0232296 (UMLS CUI [1])
Incomplete right bundle branch block
Item
Incomplete right bundle branch block
boolean
C0262525 (UMLS CUI [1])
Incomplete left bundle branch block
Item
Incomplete left bundle branch block
boolean
C0281878 (UMLS CUI [1])
Right bundle branch block
Item
Right bundle branch block
boolean
C0085615 (UMLS CUI [1])
Left anterior hemiblock
Item
Left anterior hemiblock
boolean
C0264912 (UMLS CUI [1])
Left posterior hemiblock
Item
Left posterior hemiblock
boolean
C0264913 (UMLS CUI [1])
Left bundle branch block
Item
Left bundle branch block
boolean
C0023211 (UMLS CUI [1])
Bifascicular block
Item
Bifascicular block
boolean
C0264914 (UMLS CUI [1])
Non-specific intraventricular conduction delay
Item
Non-specific intraventricular conduction delay (QRS >= 120 msec)
boolean
C3697597 (UMLS CUI [1])
Accessory pathway in Wolff-Parkinson White/Lown-Ganong-Levine Syndrome
Item
Accessory pathway (Wolff-Parkinson White, Lown-Ganong-Levine)
boolean
C1963785 (UMLS CUI [1,1])
C0043202 (UMLS CUI [1,2])
C1963785 (UMLS CUI [2,1])
C0024054 (UMLS CUI [2,2])
QTc prolongation
Item
QTc prolongation >=500msec
boolean
C0855333 (UMLS CUI [1])
C0489625 (UMLS CUI [2])
AV dissociation
Item
AV dissociation
boolean
C0004331 (UMLS CUI [1])
Myocardial infarction, old
Item
Myocardial infarction, old
boolean
C0155668 (UMLS CUI [1])
Myocardial infarction, Non Q-wave
Item
Myocardial infarction, Non Q-wave
boolean
C0542269 (UMLS CUI [1])
Non-specific ST-T changes
Item
Non-specific ST-T changes
boolean
C1112720 (UMLS CUI [1])
J point elevation
Item
J point elevation
boolean
C2346597 (UMLS CUI [1])
ST elevation
Item
ST elevation
boolean
C0520886 (UMLS CUI [1])
ST depression
Item
ST depression
boolean
C0520887 (UMLS CUI [1])
ST segment abnormality
Item
ST segment abnormality
boolean
C2348120 (UMLS CUI [1])
U waves
Item
U waves
boolean
C0232333 (UMLS CUI [1])
T wave inversion
Item
T wave inversion
boolean
C0520888 (UMLS CUI [1])
T wave peaked
Item
T wave peaked
boolean
C0239242 (UMLS CUI [1])
T waves biphasic
Item
T waves biphasic
boolean
C2348639 (UMLS CUI [1])
T waves flat
Item
T waves flat
boolean
C2215959 (UMLS CUI [1])
Notched T-waves
Item
Notched T-waves
boolean
C2347367 (UMLS CUI [1])
Low QRS voltage
Item
Low QRS voltage
boolean
C2349945 (UMLS CUI [1])
T wave abnormality
Item
T wave abnormality
boolean
C0438167 (UMLS CUI [1])
Other abnormal rhythm
Item
Other abnormal rhythm
boolean
C0205394 (UMLS CUI [1,1])
C0199556 (UMLS CUI [1,2])
C0205161 (UMLS CUI [1,3])
12 lead ECG, Abnormality, Electrocardiogram: Rhythm, Comment
Item
Comment
text
C0430456 (UMLS CUI [1,1])
C1704258 (UMLS CUI [1,2])
C0199556 (UMLS CUI [1,3])
C0947611 (UMLS CUI [1,4])
Other morphology
Item
Other morphology
boolean
C0205394 (UMLS CUI [1,1])
C0332437 (UMLS CUI [1,2])
12 lead ECG, Abnormality, electrocardiogram: P wave shifting morphology, Comment; 12 lead ECG, Abnormality, Electrocardiogram QRS complex, Comment
Item
Comment
text
C0430456 (UMLS CUI [1,1])
C1704258 (UMLS CUI [1,2])
C2216025 (UMLS CUI [1,3])
C0947611 (UMLS CUI [1,4])
C0430456 (UMLS CUI [2,1])
C1704258 (UMLS CUI [2,2])
C0429098 (UMLS CUI [2,3])
C0947611 (UMLS CUI [2,4])
Other conduction
Item
Other conduction
boolean
C0340494 (UMLS CUI [1])
12 lead ECG, Abnormality, Cardiac Conduction, Comment
Item
Comment
text
C0430456 (UMLS CUI [1,1])
C1704258 (UMLS CUI [1,2])
C0232217 (UMLS CUI [1,3])
C0947611 (UMLS CUI [1,4])
Other myocardial infarction
Item
Other myocardial infarction
boolean
C0205394 (UMLS CUI [1,1])
C0027051 (UMLS CUI [1,2])
12 lead ECG, Abnormality, Myocardial Infarction, Comment
Item
Comment
text
C0430456 (UMLS CUI [1,1])
C1704258 (UMLS CUI [1,2])
C0027051 (UMLS CUI [1,3])
C0947611 (UMLS CUI [1,4])
Other depolarisation/repolarisation
Item
Other depolarisation/repolarisation
boolean
C0205394 (UMLS CUI [1,1])
C0205161 (UMLS CUI [1,2])
C2746082 (UMLS CUI [1,3])
C0948857 (UMLS CUI [2,1])
C0205394 (UMLS CUI [2,2])
12 lead ECG, Abnormality, Ventricular Depolarization [PE], Comment; 12 lead ECG, Abnormality, Electrocardiogram repolarisation abnormality, Comment
Item
Comment
text
C0430456 (UMLS CUI [1,1])
C1704258 (UMLS CUI [1,2])
C1331539 (UMLS CUI [1,3])
C0947611 (UMLS CUI [1,4])
C0430456 (UMLS CUI [2,1])
C1704258 (UMLS CUI [2,2])
C0948857 (UMLS CUI [2,3])
C0947611 (UMLS CUI [2,4])
12 lead ECG, Abnormality, Other | Cardiologists, comment
Item
Other abnormalities/Cardiologist Comments
boolean
C0430456 (UMLS CUI [1,1])
C1704258 (UMLS CUI [1,2])
C0205394 (UMLS CUI [1,3])
C0175906 (UMLS CUI [2,1])
C0947611 (UMLS CUI [2,2])
12 lead ECG, Abnormality, Other, Comment | Cardiologists, Comment
Item
Comment
text
C0430456 (UMLS CUI [1,1])
C1704258 (UMLS CUI [1,2])
C0205394 (UMLS CUI [1,3])
C0947611 (UMLS CUI [1,4])
C0175906 (UMLS CUI [2,1])
C0947611 (UMLS CUI [2,2])
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