ID

41275

Beschreibung

The primary focus of this first time in human (FTIH) study was to evaluate the safety and tolerability of GSK1292263 and to estimate GSK1292263 pharmacokinetic (PK) parameters and pharmacodynamic (PD) effects in healthy volunteers. Subject: FTIH, oral, safety, tolerability, pharmacokinetics, glucose, pharmacodynamics, male, female, gastric emptying Indication Studied: Type 2 Diabetes Mellitis Study ID: 111596 Clinical Study ID: 111596 Study Title: A study in healthy volunteers of single doses of orally administered GSK1292263 to investigate the safety, tolerability, pharmacokinetics and pharmacodynamics of the compound alone and when co-administered with sitagliptin Patient Level Data: Study Listed on ClinicalStudyDataRequest.com Clinicaltrials.gov Identifier: NCT00783549 Sponsor: GlaxoSmithKline Collaborators: N/A Phase: Phase 1 Study Recruitment Status: Completed Generic Name: GSK1292263, Sitagliptin Trade Name: N/A Study Indication: Dyslipidaemias

Stichworte

Versionen (1)
  1. 10.08.20 10.08.20 -
Rechteinhaber

GlaxoSmithKline

Hochgeladen am

10. August 2020

DOI

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A study in healthy volunteers of single doses of orally administered GSK1292263 to investigate the safety, tolerability, pharmacokinetics and pharmacodynamics of the compound alone and when co-administered with sitagliptin

Englisch

Summary Telemetry Abnormalities V6 14-DF

1 Formulare  
RECORD CLINICALLY SIGNIFICANT ABNORMALITIES BELOW
Beschreibung

RECORD CLINICALLY SIGNIFICANT ABNORMALITIES BELOW

Alias
UMLS CUI-1
C0039451
UMLS CUI-2
C1704258
No abnormalities
Beschreibung

No Telemetry Abnormalities

Datentyp

boolean

Alias
UMLS CUI [1,1]
C0039451
UMLS CUI [1,2]
C0438154
Sinus bradycardia (50-59 beats/min)
Beschreibung

Sinus bradycardia (50-59 beats/min)

Datentyp

boolean

Alias
UMLS CUI [1,1]
C0085610
UMLS CUI [1,2]
C0018810
Sinus bradycardia (40-49 beats/min)
Beschreibung

Sinus bradycardia (40-49 beats/min)

Datentyp

boolean

Alias
UMLS CUI [1,1]
C0085610
UMLS CUI [1,2]
C0018810
Sinus bradycardia (30-39 beats/min)
Beschreibung

Sinus bradycardia (30-39 beats/min)

Datentyp

boolean

Alias
UMLS CUI [1,1]
C0085610
UMLS CUI [1,2]
C0018810
Sinus bradycardia (<30 beats/min)
Beschreibung

Sinus bradycardia (<30 beats/min)

Datentyp

boolean

Alias
UMLS CUI [1,1]
C0085610
UMLS CUI [1,2]
C0018810
Sinus pause
Beschreibung

Sinus pause

Datentyp

boolean

Alias
UMLS CUI [1]
C1955864
Sinus tachycardia (heart rate > 100 beats/min)
Beschreibung

Sinus tachycardia

Datentyp

boolean

Alias
UMLS CUI [1,1]
C0039239
UMLS CUI [1,2]
C0018810
Ectopic supraventricular beats
Beschreibung

Ectopic supraventricular beats

Datentyp

boolean

Alias
UMLS CUI [1]
C0033036
Ectopic supraventricular rhythm
Beschreibung

Ectopic supraventricular rhythm

Datentyp

boolean

Alias
UMLS CUI [1]
C2348376
Wandering atrial pacemaker
Beschreibung

Wandering atrial pacemaker

Datentyp

boolean

Alias
UMLS CUI [1]
C1321523
Multifocal atrial tachycardia (wandering atrial pacemaker with heart rate > 100 beats/min)
Beschreibung

Multifocal atrial tachycardia

Datentyp

boolean

Alias
UMLS CUI [1,1]
C0221158
UMLS CUI [1,2]
C0018810
Non-sustained supraventricular tachycardia (>100 beats/min, 3-30 beats)
Beschreibung

Non-sustained supraventricular tachycardia

Datentyp

boolean

Alias
UMLS CUI [1,1]
C0039240
UMLS CUI [1,2]
C0018810
UMLS CUI [1,3]
C0205374
Sustained supraventricular tachycardia, (>100 beats/min, >30 beats)
Beschreibung

Sustained supraventricular tachycardia

Datentyp

boolean

Alias
UMLS CUI [1,1]
C0039240
UMLS CUI [1,2]
C0443318
UMLS CUI [1,3]
C0018810
Atrial flutter
Beschreibung

Atrial flutter

Datentyp

boolean

Alias
UMLS CUI [1]
C0004239
Atrial fibrillation
Beschreibung

Atrial fibrillation

Datentyp

boolean

Alias
UMLS CUI [1]
C0004238
Junctional rhythm (<= 100 beats/min, defined by narrow QRS complex)
Beschreibung

Junctional rhythm (<= 100 beats/min, defined by narrow QRS complex)

Datentyp

boolean

Alias
UMLS CUI [1,1]
C0232208
UMLS CUI [1,2]
C0018810
Junctional tachycardia (heart rate > 100 beats/min)
Beschreibung

Junctional tachycardia

Datentyp

boolean

Alias
UMLS CUI [1,1]
C0039235
UMLS CUI [1,2]
C0018810
Ventricular premature depolarisation
Beschreibung

Ventricular premature depolarisation

Datentyp

boolean

Alias
UMLS CUI [1]
C0151636
Ventricular couplets
Beschreibung

Ventricular couplets

Datentyp

boolean

Alias
UMLS CUI [1]
C0429001
Bigeminy
Beschreibung

Bigeminy

Datentyp

boolean

Alias
UMLS CUI [1]
C0262662
Trigeminy
Beschreibung

Trigeminy

Datentyp

boolean

Alias
UMLS CUI [1]
C0428999
Electrical alternans
Beschreibung

Electrical alternans

Datentyp

boolean

Alias
UMLS CUI [1]
C1142551
R on T phenomenon
Beschreibung

R on T phenomenon

Datentyp

boolean

Alias
UMLS CUI [1]
C0877658
Ventricular fibrillation
Beschreibung

Ventricular fibrillation

Datentyp

boolean

Alias
UMLS CUI [1]
C0042510
ldioventricular rhythm (<= 100 beats/min, defined by wide QRS complex)
Beschreibung

ldioventricular rhythm

Datentyp

boolean

Alias
UMLS CUI [1]
C0700363
Non-sustained ventricular tachycardia (>100 beats/min, 3-30 beats)
Beschreibung

Non-sustained ventricular tachycardia

Datentyp

boolean

Alias
UMLS CUI [1]
C0750194
Sustained ventricular tachycardia (<100 beats/min, >30 beats)
Beschreibung

Sustained ventricular tachycardia

Datentyp

boolean

Alias
UMLS CUI [1]
C0750197
Wide QRS tachycardia (diagnosis unknown)
Beschreibung

Wide QRS tachycardia

Datentyp

boolean

Alias
UMLS CUI [1,1]
C0344429
UMLS CUI [1,2]
C0439673
UMLS CUI [1,3]
C0011900
Monomorphic non-sustained ventricular tachycardia (>100 beats/min, 3-30 beats)
Beschreibung

Monomorphic non-sustained ventricular tachycardia (>100 beats/min, 3-30 beats)

Datentyp

boolean

Alias
UMLS CUI [1,1]
C0344431
UMLS CUI [1,2]
C0750194
Monomorphic sustained ventricular tachycardia (> 100 beats/min, >30 beats)
Beschreibung

Monomorphic sustained ventricular tachycardia (> 100 beats/min, >30 beats)

Datentyp

boolean

Alias
UMLS CUI [1,1]
C0344431
UMLS CUI [1,2]
C0750197
Polymorphic non-sustained ventricular tachycardia (>100 beats/min, 3-30 beats)
Beschreibung

Polymorphic non-sustained ventricular tachycardia (>100 beats/min, 3-30 beats)

Datentyp

boolean

Alias
UMLS CUI [1,1]
C0344432
UMLS CUI [1,2]
C0750194
Polymorphic sustained ventricular tachycardia (>100 beats/min, >30 beats)
Beschreibung

Polymorphic sustained ventricular tachycardia (>100 beats/min, >30 beats)

Datentyp

boolean

Alias
UMLS CUI [1,1]
C0344432
UMLS CUI [1,2]
C0750197
Torsades de Pointes (TdP)
Beschreibung

Torsades de Pointes

Datentyp

boolean

Alias
UMLS CUI [1]
C0040479
Pacemaker
Beschreibung

Artificial Pacemaker

Datentyp

boolean

Alias
UMLS CUI [1]
C0030163
First degree AV block (PR interval> 200msec)
Beschreibung

First degree AV block

Datentyp

boolean

Alias
UMLS CUI [1]
C0085614
Short PR interval
Beschreibung

Short PR interval

Datentyp

boolean

Alias
UMLS CUI [1]
C0520878
Second degree AV block (Mobitz type 1)
Beschreibung

Second degree AV block (Mobitz type 1)

Datentyp

boolean

Alias
UMLS CUI [1]
C0264907
Second degree AV block (Mobitz type 2)
Beschreibung

Second degree AV block (Mobitz type 2)

Datentyp

boolean

Alias
UMLS CUI [1]
C0155700
2: 1 AV block
Beschreibung

2: 1 AV block

Datentyp

boolean

Alias
UMLS CUI [1]
C2346542
Third degree AV block
Beschreibung

Third degree AV block

Datentyp

boolean

Alias
UMLS CUI [1]
C0151517
Left axis deviation (QRS axis more negative than -30 degrees)
Beschreibung

Left axis deviation

Datentyp

boolean

Alias
UMLS CUI [1]
C0232297
Right axis deviation (QRS axis more positive than +110 degrees)
Beschreibung

Right axis deviation

Datentyp

boolean

Alias
UMLS CUI [1]
C0232296
Incomplete right bundle branch block
Beschreibung

Incomplete right bundle branch block

Datentyp

boolean

Alias
UMLS CUI [1]
C0262525
Incomplete left bundle branch block
Beschreibung

Incomplete left bundle branch block

Datentyp

boolean

Alias
UMLS CUI [1]
C0281878
Right bundle branch block
Beschreibung

Right bundle branch block

Datentyp

boolean

Alias
UMLS CUI [1]
C0085615
Left anterior hemiblock
Beschreibung

Left anterior hemiblock

Datentyp

boolean

Alias
UMLS CUI [1]
C0264912
Left posterior hemiblock
Beschreibung

Left posterior hemiblock

Datentyp

boolean

Alias
UMLS CUI [1]
C0264913
Left bundle branch block
Beschreibung

Left bundle branch block

Datentyp

boolean

Alias
UMLS CUI [1]
C0023211
Bifascicular block
Beschreibung

Bifascicular block

Datentyp

boolean

Alias
UMLS CUI [1]
C0264914
Non-specific intraventricular conduction delay (QRS >= 120 msec)
Beschreibung

Non-specific intraventricular conduction delay

Datentyp

boolean

Alias
UMLS CUI [1]
C3697597
Accessory pathway (Wolff-Parkinson White, Lown-Ganong-Levine)
Beschreibung

Accessory pathway in Wolff-Parkinson White/Lown-Ganong-Levine Syndrome

Datentyp

boolean

Alias
UMLS CUI [1,1]
C1963785
UMLS CUI [1,2]
C0043202
UMLS CUI [2,1]
C1963785
UMLS CUI [2,2]
C0024054
QTc prolongation >=500msec
Beschreibung

QTc prolongation

Datentyp

boolean

Alias
UMLS CUI [1]
C0855333
UMLS CUI [2]
C0489625
AV dissociation
Beschreibung

AV dissociation

Datentyp

boolean

Alias
UMLS CUI [1]
C0004331
Myocardial infarction, old
Beschreibung

Myocardial infarction, old

Datentyp

boolean

Alias
UMLS CUI [1]
C0155668
Myocardial infarction, Non Q-wave
Beschreibung

Myocardial infarction, Non Q-wave

Datentyp

boolean

Alias
UMLS CUI [1]
C0542269
Non-specific ST-T changes
Beschreibung

Non-specific ST-T changes

Datentyp

boolean

Alias
UMLS CUI [1]
C1112720
J point elevation
Beschreibung

J point elevation

Datentyp

boolean

Alias
UMLS CUI [1]
C2346597
ST elevation
Beschreibung

ST elevation

Datentyp

boolean

Alias
UMLS CUI [1]
C0520886
ST depression
Beschreibung

ST depression

Datentyp

boolean

Alias
UMLS CUI [1]
C0520887
ST segment abnormality
Beschreibung

ST segment abnormality

Datentyp

boolean

Alias
UMLS CUI [1]
C2348120
U waves
Beschreibung

U waves

Datentyp

boolean

Alias
UMLS CUI [1]
C0232333
T wave inversion
Beschreibung

T wave inversion

Datentyp

boolean

Alias
UMLS CUI [1]
C0520888
T wave peaked
Beschreibung

T wave peaked

Datentyp

boolean

Alias
UMLS CUI [1]
C0239242
T waves biphasic
Beschreibung

T waves biphasic

Datentyp

boolean

Alias
UMLS CUI [1]
C2348639
T waves flat
Beschreibung

T waves flat

Datentyp

boolean

Alias
UMLS CUI [1]
C2215959
Notched T-waves
Beschreibung

Notched T-waves

Datentyp

boolean

Alias
UMLS CUI [1]
C2347367
Low QRS voltage
Beschreibung

Low QRS voltage

Datentyp

boolean

Alias
UMLS CUI [1]
C2349945
T wave abnormality
Beschreibung

T wave abnormality

Datentyp

boolean

Alias
UMLS CUI [1]
C0438167
Other abnormal rhythm
Beschreibung

If yes, enter comment

Datentyp

boolean

Alias
UMLS CUI [1,1]
C0205394
UMLS CUI [1,2]
C0199556
UMLS CUI [1,3]
C0205161
Comment
Beschreibung

12 lead ECG, Abnormality, Electrocardiogram: Rhythm, Comment

Datentyp

text

Alias
UMLS CUI [1,1]
C0430456
UMLS CUI [1,2]
C1704258
UMLS CUI [1,3]
C0199556
UMLS CUI [1,4]
C0947611
Other morphology
Beschreibung

If yes, enter comment

Datentyp

boolean

Alias
UMLS CUI [1,1]
C0205394
UMLS CUI [1,2]
C0332437
Comment
Beschreibung

12 lead ECG, Abnormality, electrocardiogram: P wave shifting morphology, Comment; 12 lead ECG, Abnormality, Electrocardiogram QRS complex, Comment

Datentyp

text

Alias
UMLS CUI [1,1]
C0430456
UMLS CUI [1,2]
C1704258
UMLS CUI [1,3]
C2216025
UMLS CUI [1,4]
C0947611
UMLS CUI [2,1]
C0430456
UMLS CUI [2,2]
C1704258
UMLS CUI [2,3]
C0429098
UMLS CUI [2,4]
C0947611
Other conduction
Beschreibung

If yes, enter comment

Datentyp

boolean

Alias
UMLS CUI [1]
C0340494
Comment
Beschreibung

12 lead ECG, Abnormality, Cardiac Conduction, Comment

Datentyp

text

Alias
UMLS CUI [1,1]
C0430456
UMLS CUI [1,2]
C1704258
UMLS CUI [1,3]
C0232217
UMLS CUI [1,4]
C0947611
Other myocardial infarction
Beschreibung

If yes, enter comment

Datentyp

boolean

Alias
UMLS CUI [1,1]
C0205394
UMLS CUI [1,2]
C0027051
Comment
Beschreibung

12 lead ECG, Abnormality, Myocardial Infarction, Comment

Datentyp

text

Alias
UMLS CUI [1,1]
C0430456
UMLS CUI [1,2]
C1704258
UMLS CUI [1,3]
C0027051
UMLS CUI [1,4]
C0947611
Other depolarisation/repolarisation
Beschreibung

If yes, enter comment

Datentyp

boolean

Alias
UMLS CUI [1,1]
C0205394
UMLS CUI [1,2]
C0205161
UMLS CUI [1,3]
C2746082
UMLS CUI [2,1]
C0948857
UMLS CUI [2,2]
C0205394
Comment
Beschreibung

12 lead ECG, Abnormality, Ventricular Depolarization [PE], Comment; 12 lead ECG, Abnormality, Electrocardiogram repolarisation abnormality, Comment

Datentyp

text

Alias
UMLS CUI [1,1]
C0430456
UMLS CUI [1,2]
C1704258
UMLS CUI [1,3]
C1331539
UMLS CUI [1,4]
C0947611
UMLS CUI [2,1]
C0430456
UMLS CUI [2,2]
C1704258
UMLS CUI [2,3]
C0948857
UMLS CUI [2,4]
C0947611
Other abnormalities/Cardiologist Comments
Beschreibung

12 lead ECG, Abnormality, Other | Cardiologists, comment

Datentyp

boolean

Alias
UMLS CUI [1,1]
C0430456
UMLS CUI [1,2]
C1704258
UMLS CUI [1,3]
C0205394
UMLS CUI [2,1]
C0175906
UMLS CUI [2,2]
C0947611
Comment
Beschreibung

12 lead ECG, Abnormality, Other, Comment | Cardiologists, Comment

Datentyp

text

Alias
UMLS CUI [1,1]
C0430456
UMLS CUI [1,2]
C1704258
UMLS CUI [1,3]
C0205394
UMLS CUI [1,4]
C0947611
UMLS CUI [2,1]
C0175906
UMLS CUI [2,2]
C0947611
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Ähnliche Modelle

Summary Telemetry Abnormalities V6 14-DF

1 Formulare
Name
Typ
Description | Question | Decode (Coded Value)
Datentyp
Alias
Item Group
RECORD CLINICALLY SIGNIFICANT ABNORMALITIES BELOW
C0039451 (UMLS CUI-1)
C1704258 (UMLS CUI-2)
No Telemetry Abnormalities
Item
No abnormalities
boolean
C0039451 (UMLS CUI [1,1])
C0438154 (UMLS CUI [1,2])
Sinus bradycardia (50-59 beats/min)
Item
Sinus bradycardia (50-59 beats/min)
boolean
C0085610 (UMLS CUI [1,1])
C0018810 (UMLS CUI [1,2])
Sinus bradycardia (40-49 beats/min)
Item
Sinus bradycardia (40-49 beats/min)
boolean
C0085610 (UMLS CUI [1,1])
C0018810 (UMLS CUI [1,2])
Sinus bradycardia (30-39 beats/min)
Item
Sinus bradycardia (30-39 beats/min)
boolean
C0085610 (UMLS CUI [1,1])
C0018810 (UMLS CUI [1,2])
Sinus bradycardia (<30 beats/min)
Item
Sinus bradycardia (<30 beats/min)
boolean
C0085610 (UMLS CUI [1,1])
C0018810 (UMLS CUI [1,2])
Sinus pause
Item
Sinus pause
boolean
C1955864 (UMLS CUI [1])
Sinus tachycardia
Item
Sinus tachycardia (heart rate > 100 beats/min)
boolean
C0039239 (UMLS CUI [1,1])
C0018810 (UMLS CUI [1,2])
Ectopic supraventricular beats
Item
Ectopic supraventricular beats
boolean
C0033036 (UMLS CUI [1])
Ectopic supraventricular rhythm
Item
Ectopic supraventricular rhythm
boolean
C2348376 (UMLS CUI [1])
Wandering atrial pacemaker
Item
Wandering atrial pacemaker
boolean
C1321523 (UMLS CUI [1])
Multifocal atrial tachycardia
Item
Multifocal atrial tachycardia (wandering atrial pacemaker with heart rate > 100 beats/min)
boolean
C0221158 (UMLS CUI [1,1])
C0018810 (UMLS CUI [1,2])
Non-sustained supraventricular tachycardia
Item
Non-sustained supraventricular tachycardia (>100 beats/min, 3-30 beats)
boolean
C0039240 (UMLS CUI [1,1])
C0018810 (UMLS CUI [1,2])
C0205374 (UMLS CUI [1,3])
Sustained supraventricular tachycardia
Item
Sustained supraventricular tachycardia, (>100 beats/min, >30 beats)
boolean
C0039240 (UMLS CUI [1,1])
C0443318 (UMLS CUI [1,2])
C0018810 (UMLS CUI [1,3])
Atrial flutter
Item
Atrial flutter
boolean
C0004239 (UMLS CUI [1])
Atrial fibrillation
Item
Atrial fibrillation
boolean
C0004238 (UMLS CUI [1])
Junctional rhythm (<= 100 beats/min, defined by narrow QRS complex)
Item
Junctional rhythm (<= 100 beats/min, defined by narrow QRS complex)
boolean
C0232208 (UMLS CUI [1,1])
C0018810 (UMLS CUI [1,2])
Junctional tachycardia
Item
Junctional tachycardia (heart rate > 100 beats/min)
boolean
C0039235 (UMLS CUI [1,1])
C0018810 (UMLS CUI [1,2])
Ventricular premature depolarisation
Item
Ventricular premature depolarisation
boolean
C0151636 (UMLS CUI [1])
Ventricular couplets
Item
Ventricular couplets
boolean
C0429001 (UMLS CUI [1])
Bigeminy
Item
Bigeminy
boolean
C0262662 (UMLS CUI [1])
Trigeminy
Item
Trigeminy
boolean
C0428999 (UMLS CUI [1])
Electrical alternans
Item
Electrical alternans
boolean
C1142551 (UMLS CUI [1])
R on T phenomenon
Item
R on T phenomenon
boolean
C0877658 (UMLS CUI [1])
Ventricular fibrillation
Item
Ventricular fibrillation
boolean
C0042510 (UMLS CUI [1])
ldioventricular rhythm
Item
ldioventricular rhythm (<= 100 beats/min, defined by wide QRS complex)
boolean
C0700363 (UMLS CUI [1])
Non-sustained ventricular tachycardia
Item
Non-sustained ventricular tachycardia (>100 beats/min, 3-30 beats)
boolean
C0750194 (UMLS CUI [1])
Sustained ventricular tachycardia
Item
Sustained ventricular tachycardia (<100 beats/min, >30 beats)
boolean
C0750197 (UMLS CUI [1])
Wide QRS tachycardia
Item
Wide QRS tachycardia (diagnosis unknown)
boolean
C0344429 (UMLS CUI [1,1])
C0439673 (UMLS CUI [1,2])
C0011900 (UMLS CUI [1,3])
Monomorphic non-sustained ventricular tachycardia (>100 beats/min, 3-30 beats)
Item
Monomorphic non-sustained ventricular tachycardia (>100 beats/min, 3-30 beats)
boolean
C0344431 (UMLS CUI [1,1])
C0750194 (UMLS CUI [1,2])
Monomorphic sustained ventricular tachycardia (> 100 beats/min, >30 beats)
Item
Monomorphic sustained ventricular tachycardia (> 100 beats/min, >30 beats)
boolean
C0344431 (UMLS CUI [1,1])
C0750197 (UMLS CUI [1,2])
Polymorphic non-sustained ventricular tachycardia (>100 beats/min, 3-30 beats)
Item
Polymorphic non-sustained ventricular tachycardia (>100 beats/min, 3-30 beats)
boolean
C0344432 (UMLS CUI [1,1])
C0750194 (UMLS CUI [1,2])
Polymorphic sustained ventricular tachycardia (>100 beats/min, >30 beats)
Item
Polymorphic sustained ventricular tachycardia (>100 beats/min, >30 beats)
boolean
C0344432 (UMLS CUI [1,1])
C0750197 (UMLS CUI [1,2])
Torsades de Pointes
Item
Torsades de Pointes (TdP)
boolean
C0040479 (UMLS CUI [1])
Artificial Pacemaker
Item
Pacemaker
boolean
C0030163 (UMLS CUI [1])
First degree AV block
Item
First degree AV block (PR interval> 200msec)
boolean
C0085614 (UMLS CUI [1])
Short PR interval
Item
Short PR interval
boolean
C0520878 (UMLS CUI [1])
Second degree AV block (Mobitz type 1)
Item
Second degree AV block (Mobitz type 1)
boolean
C0264907 (UMLS CUI [1])
Second degree AV block (Mobitz type 2)
Item
Second degree AV block (Mobitz type 2)
boolean
C0155700 (UMLS CUI [1])
2: 1 AV block
Item
2: 1 AV block
boolean
C2346542 (UMLS CUI [1])
Third degree AV block
Item
Third degree AV block
boolean
C0151517 (UMLS CUI [1])
Left axis deviation
Item
Left axis deviation (QRS axis more negative than -30 degrees)
boolean
C0232297 (UMLS CUI [1])
Right axis deviation
Item
Right axis deviation (QRS axis more positive than +110 degrees)
boolean
C0232296 (UMLS CUI [1])
Incomplete right bundle branch block
Item
Incomplete right bundle branch block
boolean
C0262525 (UMLS CUI [1])
Incomplete left bundle branch block
Item
Incomplete left bundle branch block
boolean
C0281878 (UMLS CUI [1])
Right bundle branch block
Item
Right bundle branch block
boolean
C0085615 (UMLS CUI [1])
Left anterior hemiblock
Item
Left anterior hemiblock
boolean
C0264912 (UMLS CUI [1])
Left posterior hemiblock
Item
Left posterior hemiblock
boolean
C0264913 (UMLS CUI [1])
Left bundle branch block
Item
Left bundle branch block
boolean
C0023211 (UMLS CUI [1])
Bifascicular block
Item
Bifascicular block
boolean
C0264914 (UMLS CUI [1])
Non-specific intraventricular conduction delay
Item
Non-specific intraventricular conduction delay (QRS >= 120 msec)
boolean
C3697597 (UMLS CUI [1])
Accessory pathway in Wolff-Parkinson White/Lown-Ganong-Levine Syndrome
Item
Accessory pathway (Wolff-Parkinson White, Lown-Ganong-Levine)
boolean
C1963785 (UMLS CUI [1,1])
C0043202 (UMLS CUI [1,2])
C1963785 (UMLS CUI [2,1])
C0024054 (UMLS CUI [2,2])
QTc prolongation
Item
QTc prolongation >=500msec
boolean
C0855333 (UMLS CUI [1])
C0489625 (UMLS CUI [2])
AV dissociation
Item
AV dissociation
boolean
C0004331 (UMLS CUI [1])
Myocardial infarction, old
Item
Myocardial infarction, old
boolean
C0155668 (UMLS CUI [1])
Myocardial infarction, Non Q-wave
Item
Myocardial infarction, Non Q-wave
boolean
C0542269 (UMLS CUI [1])
Non-specific ST-T changes
Item
Non-specific ST-T changes
boolean
C1112720 (UMLS CUI [1])
J point elevation
Item
J point elevation
boolean
C2346597 (UMLS CUI [1])
ST elevation
Item
ST elevation
boolean
C0520886 (UMLS CUI [1])
ST depression
Item
ST depression
boolean
C0520887 (UMLS CUI [1])
ST segment abnormality
Item
ST segment abnormality
boolean
C2348120 (UMLS CUI [1])
U waves
Item
U waves
boolean
C0232333 (UMLS CUI [1])
T wave inversion
Item
T wave inversion
boolean
C0520888 (UMLS CUI [1])
T wave peaked
Item
T wave peaked
boolean
C0239242 (UMLS CUI [1])
T waves biphasic
Item
T waves biphasic
boolean
C2348639 (UMLS CUI [1])
T waves flat
Item
T waves flat
boolean
C2215959 (UMLS CUI [1])
Notched T-waves
Item
Notched T-waves
boolean
C2347367 (UMLS CUI [1])
Low QRS voltage
Item
Low QRS voltage
boolean
C2349945 (UMLS CUI [1])
T wave abnormality
Item
T wave abnormality
boolean
C0438167 (UMLS CUI [1])
Other abnormal rhythm
Item
Other abnormal rhythm
boolean
C0205394 (UMLS CUI [1,1])
C0199556 (UMLS CUI [1,2])
C0205161 (UMLS CUI [1,3])
12 lead ECG, Abnormality, Electrocardiogram: Rhythm, Comment
Item
Comment
text
C0430456 (UMLS CUI [1,1])
C1704258 (UMLS CUI [1,2])
C0199556 (UMLS CUI [1,3])
C0947611 (UMLS CUI [1,4])
Other morphology
Item
Other morphology
boolean
C0205394 (UMLS CUI [1,1])
C0332437 (UMLS CUI [1,2])
12 lead ECG, Abnormality, electrocardiogram: P wave shifting morphology, Comment; 12 lead ECG, Abnormality, Electrocardiogram QRS complex, Comment
Item
Comment
text
C0430456 (UMLS CUI [1,1])
C1704258 (UMLS CUI [1,2])
C2216025 (UMLS CUI [1,3])
C0947611 (UMLS CUI [1,4])
C0430456 (UMLS CUI [2,1])
C1704258 (UMLS CUI [2,2])
C0429098 (UMLS CUI [2,3])
C0947611 (UMLS CUI [2,4])
Other conduction
Item
Other conduction
boolean
C0340494 (UMLS CUI [1])
12 lead ECG, Abnormality, Cardiac Conduction, Comment
Item
Comment
text
C0430456 (UMLS CUI [1,1])
C1704258 (UMLS CUI [1,2])
C0232217 (UMLS CUI [1,3])
C0947611 (UMLS CUI [1,4])
Other myocardial infarction
Item
Other myocardial infarction
boolean
C0205394 (UMLS CUI [1,1])
C0027051 (UMLS CUI [1,2])
12 lead ECG, Abnormality, Myocardial Infarction, Comment
Item
Comment
text
C0430456 (UMLS CUI [1,1])
C1704258 (UMLS CUI [1,2])
C0027051 (UMLS CUI [1,3])
C0947611 (UMLS CUI [1,4])
Other depolarisation/repolarisation
Item
Other depolarisation/repolarisation
boolean
C0205394 (UMLS CUI [1,1])
C0205161 (UMLS CUI [1,2])
C2746082 (UMLS CUI [1,3])
C0948857 (UMLS CUI [2,1])
C0205394 (UMLS CUI [2,2])
12 lead ECG, Abnormality, Ventricular Depolarization [PE], Comment; 12 lead ECG, Abnormality, Electrocardiogram repolarisation abnormality, Comment
Item
Comment
text
C0430456 (UMLS CUI [1,1])
C1704258 (UMLS CUI [1,2])
C1331539 (UMLS CUI [1,3])
C0947611 (UMLS CUI [1,4])
C0430456 (UMLS CUI [2,1])
C1704258 (UMLS CUI [2,2])
C0948857 (UMLS CUI [2,3])
C0947611 (UMLS CUI [2,4])
12 lead ECG, Abnormality, Other | Cardiologists, comment
Item
Other abnormalities/Cardiologist Comments
boolean
C0430456 (UMLS CUI [1,1])
C1704258 (UMLS CUI [1,2])
C0205394 (UMLS CUI [1,3])
C0175906 (UMLS CUI [2,1])
C0947611 (UMLS CUI [2,2])
12 lead ECG, Abnormality, Other, Comment | Cardiologists, Comment
Item
Comment
text
C0430456 (UMLS CUI [1,1])
C1704258 (UMLS CUI [1,2])
C0205394 (UMLS CUI [1,3])
C0947611 (UMLS CUI [1,4])
C0175906 (UMLS CUI [2,1])
C0947611 (UMLS CUI [2,2])
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