ID

41043

Descripción

This form documents the liver biopsy. To be assessed at liver event visit. Study ID: 103629 Clinical Study ID: TRX103629 Study Title: An open-label, randomized, 3-period crossover study to evaluate sumatriptan and naproxen pharmacokinetics for a combination tablet product containing sumatriptan/naproxen sodium followed by IMITREX™ (sumatriptan succinate) Injection 4mg administered using the IMITREX STATdose System and a sumatriptan/naproxen sodium tablet followed by IMITREX (sumatriptan succinate) Injection 6mg administered using the STATdose system compared with an IMITREX tablet 100mg followed by an IMITREX tablet 100mg Patient Level Data: Study Listed on ClinicalStudyDataRequest.com Clinicaltrials.gov Identifier: NCT00875784 Clinicaltrials.gov link: https://clinicaltrials.gov/ct2/show/NCT00875784 Sponsor: GlaxoSmithKline Collaborators: N/A Phase: phase 1 Study Recruitment Status: Completed Generic Name: sumatriptan Trade Name: Imitrex ,Imiject ,Imigran; Imitrex,Imiject,Imigran Study Indication: Migraine Disorders

Link

https://clinicaltrials.gov/ct2/show/NCT00875784

Palabras clave

  1. 16/6/20 16/6/20 -
Titular de derechos de autor

GlaxoSmithKline

Subido en

16 de junio de 2020

DOI

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Licencia

Creative Commons BY-NC 4.0

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Sumatriptan pharmacokinetics for TREXIMA/IMITREX ID 103629

Liver biopsy

  1. StudyEvent: ODM
    1. Liver biopsy
Administrative Data
Descripción

Administrative Data

Alias
UMLS CUI-1
C1320722
Subject Identifier
Descripción

Subject Identifier

Tipo de datos

integer

Alias
UMLS CUI [1]
C2348585
Date of visit/assessment
Descripción

Date of Visit/Assessment

Tipo de datos

date

Alias
UMLS CUI [1]
C1320303
Date of liver biopsy
Descripción

Date of liver biopsy

Alias
UMLS CUI-1
C0193388
UMLS CUI-2
C0011008
1. Date of liver biopsy
Descripción

Date of liver biopsy

Tipo de datos

date

Alias
UMLS CUI [1,1]
C0193388
UMLS CUI [1,2]
C0011008
Biopsy size
Descripción

Biopsy size

Alias
UMLS CUI-1
C1299482
UMLS CUI-2
C0193388
2. Approximate size of liver biopsy
Descripción

Liver Biopsy size

Tipo de datos

integer

Unidades de medida
  • mm
Alias
UMLS CUI [1,1]
C1299482
UMLS CUI [1,2]
C0193388
mm
Final Diagnosis
Descripción

Final Diagnosis

Alias
UMLS CUI-1
C1546485
UMLS CUI-2
C0193388
3. Final Diagnosis
Descripción

Final Diagnosis

Tipo de datos

text

Alias
UMLS CUI [1,1]
C1546485
UMLS CUI [1,2]
C0193388
Acute hepatitis
Descripción

Acute hepatitis

Tipo de datos

boolean

Alias
UMLS CUI [1]
C0267797
Chronic hepatitis
Descripción

Chronic hepatitis

Tipo de datos

boolean

Alias
UMLS CUI [1]
C0019189
Cholestatic hepatitis
Descripción

Cholestatic hepatitis

Tipo de datos

boolean

Alias
UMLS CUI [1]
C0149904
Drug-induced cholestasis
Descripción

Drug-induced cholestasis

Tipo de datos

boolean

Alias
UMLS CUI [1]
C2062350
Acute viral hepatitis
Descripción

Acute viral hepatitis

Tipo de datos

boolean

Alias
UMLS CUI [1]
C0276622
Chronic viral hepatitis
Descripción

Chronic viral hepatitis

Tipo de datos

boolean

Alias
UMLS CUI [1]
C0276623
Drug-induced hepatitis
Descripción

Drug-induced hepatitis

Tipo de datos

boolean

Alias
UMLS CUI [1]
C1262760
Autoimmune hepatitis
Descripción

Autoimmune hepatitis

Tipo de datos

boolean

Alias
UMLS CUI [1]
C0241910
Bridging necrosis
Descripción

Liver Bridging necrosis

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C0333511
UMLS CUI [1,2]
C0023884
Submassive hepatic necrosis
Descripción

Submassive hepatic necrosis

Tipo de datos

boolean

Alias
UMLS CUI [1]
C0151798
Massive hepatic necrosis
Descripción

Massive hepatic necrosis

Tipo de datos

boolean

Alias
UMLS CUI [1]
C0001364
Steatosis - microvesicular
Descripción

Steatosis - microvesicular

Tipo de datos

boolean

Alias
UMLS CUI [1]
C1850415
Steatosis - macrovesicular
Descripción

Steatosis - macrovesicular

Tipo de datos

boolean

Alias
UMLS CUI [1]
C1837256
Steatosis - mixed
Descripción

Steatosis - mixed

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C0015695
UMLS CUI [1,2]
C0205430
Non-alcoholic steatohepatitis
Descripción

Non-alcoholic steatohepatitis

Tipo de datos

boolean

Alias
UMLS CUI [1]
C3241937
Alcoholic hepatitis
Descripción

Alcoholic hepatitis

Tipo de datos

boolean

Alias
UMLS CUI [1]
C0019187
Hepatic granulomas
Descripción

Hepatic granulomas

Tipo de datos

boolean

Alias
UMLS CUI [1]
C0745754
Sarcoidosis
Descripción

Liver Sarcoidosis

Tipo de datos

boolean

Alias
UMLS CUI [1]
C0744822
Fibrosis
Descripción

Liver Fibrosis

Tipo de datos

boolean

Alias
UMLS CUI [1]
C0239946
Cirrhosis
Descripción

Cirrhosis

Tipo de datos

boolean

Alias
UMLS CUI [1]
C0023890
Primary biliary cirrhosis
Descripción

Primary biliary cirrhosis

Tipo de datos

boolean

Alias
UMLS CUI [1]
C0008312
Primary sclerosing cholangitis
Descripción

Primary sclerosing cholangitis

Tipo de datos

boolean

Alias
UMLS CUI [1]
C0008311
Autoimmune overlap syndrome
Descripción

Autoimmune overlap syndrome

Tipo de datos

boolean

Alias
UMLS CUI [1]
C2702837
Hemochromatosis
Descripción

Hemochromatosis

Tipo de datos

boolean

Alias
UMLS CUI [1]
C0018995
Alpha-1-antitrypsin deficiency
Descripción

Alpha-1-antitrypsin deficiency

Tipo de datos

boolean

Alias
UMLS CUI [1]
C0221757
Wilson's disease
Descripción

Wilson's disease

Tipo de datos

boolean

Alias
UMLS CUI [1]
C0019202
Veno-occlusive disease
Descripción

Liver: Veno-occlusive disease

Tipo de datos

boolean

Alias
UMLS CUI [1]
C0019156
Budd-Chiari syndrome
Descripción

Budd-Chiari syndrome

Tipo de datos

boolean

Alias
UMLS CUI [1]
C0856761
Neoplasia
Descripción

Liver Neoplasia

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C1882062
UMLS CUI [1,2]
C0023884
Other
Descripción

Other Final Diagnosis

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C1546485
UMLS CUI [1,2]
C0205394
Other, specify:
Descripción

Other Final Diagnosis specification

Tipo de datos

text

Alias
UMLS CUI [1,1]
C1546485
UMLS CUI [1,2]
C0205394
UMLS CUI [1,3]
C2348235
Liver Architecture
Descripción

Liver Architecture

Alias
UMLS CUI-1
C0023884
UMLS CUI-2
C0935919
4. Liver Architecture
Descripción

Liver Architecture

Tipo de datos

text

Alias
UMLS CUI [1,1]
C0935919
UMLS CUI [1,2]
C0023884
Bridging fibrosis
Descripción

Liver: Bridging fibrosis

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C0334160
UMLS CUI [1,2]
C0023884
Diffuse fibrosis
Descripción

Diffuse fibrosis

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C1265984
UMLS CUI [1,2]
C0023884
Nodular regenerative hyperplasia
Descripción

Liver: Nodular regenerative hyperplasia

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C0020510
UMLS CUI [1,2]
C0023884
Congenital hepatic fibrosis
Descripción

Congenital hepatic fibrosis

Tipo de datos

boolean

Alias
UMLS CUI [1]
C0009714
Cirrhosis
Descripción

Cirrhosis

Tipo de datos

boolean

Alias
UMLS CUI [1]
C0023890
Centrilobular congestion
Descripción

Centrilobular congestion

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C0267821
UMLS CUI [1,2]
C0442080
Endophlebitis
Descripción

Liver Endophlebitis

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C0014234
UMLS CUI [1,2]
C0023884
Veno-occlusive disease
Descripción

Liver Veno-occlusive disease

Tipo de datos

boolean

Alias
UMLS CUI [1]
C0019156
Canalicular cholestasis
Descripción

Canalicular cholestasis

Tipo de datos

boolean

Alias
UMLS CUI [1]
C3150342
Apoptosis
Descripción

Liver Apoptosis

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C0162638
UMLS CUI [1,2]
C0023884
Focal (or spotty or mild) hepatocellular necrosis
Descripción

Focal (or spotty or mild) hepatocellular necrosis

Tipo de datos

boolean

Alias
UMLS CUI [1]
C0267800
Interface hepatitis (periportal hepatitis or piecemeal necrosis)
Descripción

Interface hepatitis

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C0333515
UMLS CUI [1,2]
C0023884
Ischaemic necrosis
Descripción

Liver: Ischaemic necrosis

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C3887513
UMLS CUI [1,2]
C0023884
Centrolobular (Zone 3) necrosis
Descripción

Centrolobular necrosis

Tipo de datos

boolean

Alias
UMLS CUI [1]
C3672032
Focal coagulative necrosis
Descripción

Focal coagulative necrosis

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C1522058
UMLS CUI [1,2]
C0205234
Centrolobular (Zone 3) coagulative necrosis
Descripción

Centrolobular coagulative necrosis

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C1522058
UMLS CUI [1,2]
C0682619
Bridging hepatocellular necrosis
Descripción

Bridging hepatocellular necrosis

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C1855038
UMLS CUI [1,2]
C0333511
Massive or panlobular hepatocellular necrosis
Descripción

Massive or panlobular hepatocellular necrosis

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C1855038
UMLS CUI [1,2]
C0442131
UMLS CUI [2]
C0001364
Dysplasia
Descripción

Liver Dysplasia

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C0334044
UMLS CUI [1,2]
C0023884
Neoplasia
Descripción

Liver Neoplasia

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C1882062
UMLS CUI [1,2]
C0023884
Other
Descripción

Other Liver Architecture

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C0023884
UMLS CUI [1,2]
C0935919
UMLS CUI [1,3]
C0205394
Other, specify:
Descripción

Other Liver Architecture specification

Tipo de datos

text

Alias
UMLS CUI [1,1]
C0935919
UMLS CUI [1,2]
C0023884
UMLS CUI [1,3]
C0205394
UMLS CUI [1,4]
C2348235
Description of Liver Cells or Hepatocytes
Descripción

Description of Liver Cells or Hepatocytes

Alias
UMLS CUI-1
C0227525
UMLS CUI-2
C0678257
5. Description of Liver Cells or Hepatocytes
Descripción

Description of or Hepatocytes

Tipo de datos

text

Alias
UMLS CUI [1,1]
C0227525
UMLS CUI [1,2]
C0678257
Ballooning
Descripción

Ballooning Liver Cells or Hepatocytes

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C0333445
UMLS CUI [1,2]
C0227525
Acidophilic
Descripción

Acidophilic Liver Cells or Hepatocytes

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C0227525
UMLS CUI [1,2]
C0333931
Pseudoxanthomatous
Descripción

Pseudoxanthomatous Liver Cells or Hepatocytes

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C0227525
UMLS CUI [1,2]
C3277905
Multinucleated giant hepatocytes
Descripción

Multinucleated giant hepatocytes

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C3550474
UMLS CUI [1,2]
C1850414
Other
Descripción

Other Liver Cells or Hepatocytes

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C0227525
UMLS CUI [1,2]
C0678257
UMLS CUI [1,3]
C0205394
Other, specify:
Descripción

Other Liver Cells or Hepatocytes specification

Tipo de datos

text

Alias
UMLS CUI [1,1]
C0227525
UMLS CUI [1,2]
C0678257
UMLS CUI [1,3]
C0205394
UMLS CUI [1,4]
C2348235
Liver Cell or Hepatocyte Inclusions or Vacuoles
Descripción

Liver Cell or Hepatocyte Inclusions or Vacuoles

Alias
UMLS CUI-1
C0227525
UMLS CUI-2
C1512693
UMLS CUI-3
C0042219
8. Liver Cell or Hepatocyte Inclusions or Vacuoles
Descripción

Liver Cell or Hepatocyte Inclusions or Vacuoles

Tipo de datos

text

Alias
UMLS CUI [1,1]
C0227525
UMLS CUI [1,2]
C0042219
UMLS CUI [2,1]
C0227525
UMLS CUI [2,2]
C1512693
Macrovesicular steatosis
Descripción

Macrovesicular steatosis

Tipo de datos

boolean

Alias
UMLS CUI [1]
C1837256
Microvesicular steatosis
Descripción

Microvesicular steatosis

Tipo de datos

boolean

Alias
UMLS CUI [1]
C1850415
Bile accumulation
Descripción

Bile accumulation

Tipo de datos

boolean

Alias
UMLS CUI [1]
C3686784
Diastase-resistant, PAS-positive cytoplasmic inclusions
Descripción

Diastase-resistant, PAS-positive cytoplasmic inclusions

Tipo de datos

boolean

Alias
UMLS CUI [1]
C1856311
Alpha-1-antitrypsin inclusions
Descripción

Alpha-1-antitrypsin inclusions

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C0002191
UMLS CUI [1,2]
C1512693
UMLS CUI [1,3]
C0227525
Megamitochondria
Descripción

Megamitochondria

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C0544931
UMLS CUI [1,2]
C0227525
Mallory bodies
Descripción

Mallory bodies

Tipo de datos

boolean

Alias
UMLS CUI [1]
C0333744
"Ground Glass" inclusions
Descripción

Ground Glass inclusions

Tipo de datos

boolean

Alias
UMLS CUI [1]
C0598786
Lipofuscin pigment
Descripción

Hepatocyte Lipofuscin pigment

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C0023789
UMLS CUI [1,2]
C0227525
Hemosiderin granules
Descripción

Hemosiderin granules

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C0019113
UMLS CUI [1,2]
C0227525
Orcein-positive cytoplasmin granules
Descripción

Orcein-positive cytoplasmin granules

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C0069596
UMLS CUI [1,2]
C0227525
Protoporphyrin crystals (birefringent under polarised light)
Descripción

Protoporphyrin crystals

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C0033733
UMLS CUI [1,2]
C0227525
Uroporphyrin crystals (red fluorescence under ultraviolet light)
Descripción

Uroporphyrin crystals

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C0042093
UMLS CUI [1,2]
C0227525
Other
Descripción

Other Liver Cell or Hepatocyte Inclusions or Vacuoles

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C0227525
UMLS CUI [1,2]
C0042219
UMLS CUI [1,3]
C0205394
UMLS CUI [2,1]
C0227525
UMLS CUI [2,2]
C1512693
UMLS CUI [2,3]
C0205394
Other, specify:
Descripción

Other Liver Cell or Hepatocyte Inclusions or Vacuoles specification

Tipo de datos

text

Alias
UMLS CUI [1,1]
C0227525
UMLS CUI [1,2]
C0042219
UMLS CUI [1,3]
C0205394
UMLS CUI [2,1]
C0227525
UMLS CUI [2,2]
C1512693
UMLS CUI [2,3]
C0205394
UMLS CUI [3]
C1521902
Hepatocyte or Liver Cell Nuclear Abnormalities
Descripción

Hepatocyte or Liver Cell Nuclear Abnormalities

Alias
UMLS CUI-1
C0227525
UMLS CUI-2
C1849376
7. Hepatocyte or Liver Cell Nuclear Abnormalities
Descripción

Hepatocyte or Liver Cell Nuclear Abnormalities

Tipo de datos

text

Alias
UMLS CUI [1,1]
C0227525
UMLS CUI [1,2]
C1849376
Hepatocellular mitosis
Descripción

Hepatocellular mitosis

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C2697585
UMLS CUI [1,2]
C0026255
Binucleated or multinucleated hepatocytes
Descripción

Binucleated or multinucleated hepatocytes

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C0227525
UMLS CUI [1,2]
C0333909
UMLS CUI [2]
C4054455
CMV inclusion bodies
Descripción

CMV inclusion bodies

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C0582172
UMLS CUI [1,2]
C1366904
UMLS CUI [1,3]
C0227525
HSV inclusions
Descripción

HSV inclusions

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C0319232
UMLS CUI [1,2]
C1366904
UMLS CUI [1,3]
C0227525
Varicella inclusions
Descripción

Varicella inclusions

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C0740380
UMLS CUI [1,2]
C1366904
UMLS CUI [1,3]
C0227525
Other
Descripción

Other Hepatocyte or Liver Cell Nuclear Abnormalities

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C0227525
UMLS CUI [1,2]
C1849376
UMLS CUI [1,3]
C0205394
Other, specify:
Descripción

Other Hepatocyte or Liver Cell Nuclear Abnormalities specification

Tipo de datos

text

Alias
UMLS CUI [1,1]
C0227525
UMLS CUI [1,2]
C1849376
UMLS CUI [1,3]
C0205394
UMLS CUI [1,4]
C1521902
Liver or Lobular Infiltrates
Descripción

Liver or Lobular Infiltrates

Alias
UMLS CUI-1
C0205417
UMLS CUI-2
C1400896
UMLS CUI-4
C1400896
8. Liver or Lobular Infiltrates
Descripción

Liver or Lobular Infiltrates

Tipo de datos

text

Alias
UMLS CUI [1,1]
C0205417
UMLS CUI [1,2]
C1400896
UMLS CUI [2]
C1400896
Eosinophils
Descripción

Liver or Lobular Infiltrates Eosinophils

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C0205417
UMLS CUI [1,2]
C1400896
UMLS CUI [1,3]
C0014467
UMLS CUI [2,1]
C1400896
UMLS CUI [2,2]
C0014467
Lymphocytes
Descripción

Liver or Lobular Infiltrates Lymphocytes

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C0205417
UMLS CUI [1,2]
C1400896
UMLS CUI [1,3]
C0024264
UMLS CUI [2,1]
C1400896
UMLS CUI [2,2]
C0024264
Plasma cells
Descripción

Liver or Lobular Infiltrates Plasma cells

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C0205417
UMLS CUI [1,2]
C1400896
UMLS CUI [1,3]
C0032112
UMLS CUI [2,1]
C1400896
UMLS CUI [2,2]
C0032112
Neutrophils
Descripción

Liver or Lobular Infiltrates Neutrophils

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C0205417
UMLS CUI [1,2]
C1400896
UMLS CUI [1,3]
C0027950
UMLS CUI [2,1]
C1400896
UMLS CUI [2,2]
C0027950
Macrophages and proliferating Kupffer cells
Descripción

Liver or Lobular Infiltrates Macrophages and proliferating Kupffer cells

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C0205417
UMLS CUI [1,2]
C1400896
UMLS CUI [1,3]
C0022801
UMLS CUI [2,1]
C1400896
UMLS CUI [2,2]
C0022801
UMLS CUI [3]
C1168262
Granulomas
Descripción

Liver or Lobular Infiltrates Granulomas

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C0745754
UMLS CUI [1,2]
C0205417
UMLS CUI [2]
C0745754
Other
Descripción

Other Liver or Lobular Infiltrates

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C0205417
UMLS CUI [1,2]
C1400896
UMLS CUI [1,3]
C0205394
UMLS CUI [2,1]
C1400896
UMLS CUI [2,2]
C0205394
Other, specify:
Descripción

Other Liver or Lobular Infiltrates specification

Tipo de datos

text

Alias
UMLS CUI [1,1]
C0205417
UMLS CUI [1,2]
C1400896
UMLS CUI [1,3]
C0205394
UMLS CUI [2,1]
C1400896
UMLS CUI [2,2]
C0205394
UMLS CUI [3]
C1521902
Portal Tract Inflammation
Descripción

Portal Tract Inflammation

Alias
UMLS CUI-1
C3854488
9. Portal Tract Inflammation
Descripción

Portal Tract Inflammation

Tipo de datos

text

Alias
UMLS CUI [1]
C3854488
Eosinophils
Descripción

Portal Tract Inflammation Eosinophils

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C0014467
UMLS CUI [1,2]
C3854488
Lymphoid aggregates and/or follicles
Descripción

Portal Tract Inflammation Lymphoid aggregates and/or follicles

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C3854488
UMLS CUI [1,2]
C0229653
Plasma cells
Descripción

Portal Tract Inflammation Plasma cells

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C3854488
UMLS CUI [1,2]
C0032112
Neutrophils
Descripción

Portal Tract Inflammation Neutrophils

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C3854488
UMLS CUI [1,2]
C0027950
Histocytes and macrophages
Descripción

Portal Tract Inflammation Histocytes and macrophages

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C3854488
UMLS CUI [1,2]
C0024432
UMLS CUI [2,1]
C3854488
UMLS CUI [2,2]
C0019612
Other
Descripción

Other Portal Tract Inflammation

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C3854488
UMLS CUI [1,2]
C0205394
Other, specify:
Descripción

Other Portal Tract Inflammation specification

Tipo de datos

text

Alias
UMLS CUI [1,1]
C3854488
UMLS CUI [1,2]
C3845569
Bile Ducts
Descripción

Bile Ducts

Alias
UMLS CUI-1
C0005400
10. Bile Ducts
Descripción

Bile Ducts

Tipo de datos

text

Alias
UMLS CUI [1]
C0005400
Proliferation of bile ducts (bile ductular reaction)
Descripción

Proliferation of bile ducts

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C0005400
UMLS CUI [1,2]
C0334094
Dilation, degeneration or disruption of portal bile ducts
Descripción

Dilation, degeneration or disruption of portal bile ducts

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C0005400
UMLS CUI [1,2]
C0011164
UMLS CUI [2]
C1849767
UMLS CUI [3,1]
C0005400
UMLS CUI [3,2]
C0332453
Paucity of bile ducts
Descripción

Paucity of bile ducts

Tipo de datos

boolean

Alias
UMLS CUI [1]
C4273160
Periductal fibrosis
Descripción

Periductal fibrosis

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C0016059
UMLS CUI [1,2]
C0005400
Other
Descripción

Bile ducts Other

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C0205394
UMLS CUI [1,2]
C0005400
Other, specify
Descripción

Bile ducts Other specification

Tipo de datos

text

Alias
UMLS CUI [1,1]
C0205394
UMLS CUI [1,2]
C0005400
UMLS CUI [1,3]
C2348235
Portal Veins
Descripción

Portal Veins

Alias
UMLS CUI-1
C0032718
11. Portal Veins
Descripción

Portal Veins

Tipo de datos

text

Alias
UMLS CUI [1]
C0032718
Pyelophlebitis
Descripción

Pyelophlebitis

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C1405883
UMLS CUI [1,2]
C0032718
Thrombosis, sclerosis or occlusion of portal vein
Descripción

Thrombosis, sclerosis or occlusion of portal vein

Tipo de datos

boolean

Alias
UMLS CUI [1]
C0155773
UMLS CUI [2]
C0400960
UMLS CUI [3]
C0265029
Neoplastic invasion of portal vein
Descripción

Neoplastic invasion of portal vein

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C1709160
UMLS CUI [1,2]
C1510886
UMLS CUI [1,3]
C0032718
Granulomatous compression of portal vein
Descripción

Granulomatous compression of portal vein

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C0032718
UMLS CUI [1,2]
C0439667
UMLS CUI [1,3]
C0728907
Other
Descripción

Portal veins Other

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C0032718
UMLS CUI [1,2]
C0205394
Other, specify:
Descripción

Portal veins Other specification

Tipo de datos

text

Alias
UMLS CUI [1,1]
C0032718
UMLS CUI [1,2]
C0205394
UMLS CUI [1,3]
C2348235
Liver Infections
Descripción

Liver Infections

Alias
UMLS CUI-1
C1112211
12. Liver Infections
Descripción

Liver Infections

Tipo de datos

text

Alias
UMLS CUI [1]
C1112211
Leishmaniasis donovani
Descripción

Liver: Leishmaniasis donovani

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C0023273
UMLS CUI [1,2]
C1112211
Plasmodium falciparum
Descripción

Liver: Plasmodium falciparum

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C0032150
UMLS CUI [1,2]
C1112211
Toxoplasmosis
Descripción

Liver: Toxoplasmosis

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C0040558
UMLS CUI [1,2]
C1112211
Cryptococcus neoformans
Descripción

Liver: Cryptococcus neoformans

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C0010416
UMLS CUI [1,2]
C1112211
Histoplasma capsulatum
Descripción

Liver: Histoplasma capsulatum

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C0319941
UMLS CUI [1,2]
C1112211
Mycobacterium tuberculois
Descripción

Liver: Mycobacterium tuberculois

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C0026926
UMLS CUI [1,2]
C1112211
Other mycobacterial species
Descripción

Other mycobacterial species

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C0205394
UMLS CUI [1,2]
C0026918
UMLS CUI [1,3]
C1112211
Other
Descripción

Other Liver Infections

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C1112211
UMLS CUI [1,2]
C0205394
Other, specify:
Descripción

Other Liver Infections specification

Tipo de datos

text

Alias
UMLS CUI [1,1]
C1112211
UMLS CUI [1,2]
C0205394
UMLS CUI [1,3]
C2348235
Parasites or Ova
Descripción

Parasites or Ova

Alias
UMLS CUI-1
C0030498
UMLS CUI-2
C1267673
UMLS CUI-3
C0023884
13. Parasites or Ova
Descripción

Parasites or Ova

Tipo de datos

text

Alias
UMLS CUI [1,1]
C0030498
UMLS CUI [1,2]
C0023884
UMLS CUI [2,1]
C0555117
UMLS CUI [2,2]
C0023884
Schistosome and/or ova
Descripción

Schistosome and/or ova

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C4303012
UMLS CUI [1,2]
C0023884
UMLS CUI [2,1]
C0036315
UMLS CUI [2,2]
C0023884
Ascaris and/or ova
Descripción

Ascaris and/or ova

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C3698183
UMLS CUI [1,2]
C0023884
UMLS CUI [2,1]
C0003954
UMLS CUI [2,2]
C0023884
Toxocara and/or ova
Descripción

Toxocara and/or ova

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C0040550
UMLS CUI [1,2]
C1267673
UMLS CUI [1,3]
C0023884
UMLS CUI [2,1]
C0040550
UMLS CUI [2,2]
C0023884
Echinococcus cysts
Descripción

Echinococcus cysts

Tipo de datos

boolean

Alias
UMLS CUI [1]
C0013502
Hepatic capillariasis worms and/or ova
Descripción

Hepatic capillariasis worms and/or ova

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C0006896
UMLS CUI [1,2]
C1267673
UMLS CUI [1,3]
C0023884
UMLS CUI [2,1]
C0277202
UMLS CUI [2,2]
C0023884
Other
Descripción

Other Parasites or Ova

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C0030498
UMLS CUI [1,2]
C0205394
UMLS CUI [1,3]
C0023884
UMLS CUI [2,1]
C1267673
UMLS CUI [2,2]
C0205394
UMLS CUI [2,3]
C0023884
Other, specify:
Descripción

Other Parasites or Ova specification

Tipo de datos

text

Alias
UMLS CUI [1,1]
C0030498
UMLS CUI [1,2]
C0205394
UMLS CUI [1,3]
C0023884
UMLS CUI [2,1]
C1267673
UMLS CUI [2,2]
C0205394
UMLS CUI [2,3]
C0023884
UMLS CUI [3]
C2348235
14. Histologic Staining or Additional Studies Obtained
Descripción

14. Histologic Staining or Additional Studies Obtained

Alias
UMLS CUI-1
C0487602
UMLS CUI-2
C0430022
UMLS CUI-3
C0023884
Haematoxylin and eosin (or H & E)
Descripción

Haematoxylin and eosin

Tipo de datos

boolean

Alias
UMLS CUI [1]
C0523207
Masson
Descripción

Masson

Tipo de datos

boolean

Alias
UMLS CUI [1]
C1294297
Toluidine blue or Giemsa
Descripción

Toluidine blue or Giemsa

Tipo de datos

boolean

Alias
UMLS CUI [1]
C0523203
UMLS CUI [2]
C0017542
Prussian blue
Descripción

Prussian blue

Tipo de datos

boolean

Alias
UMLS CUI [1]
C1294004
Periodic Acidic Schiff (PAS), with or without diastase
Descripción

Periodic Acidic Schiff with or without diastase

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C0440048
UMLS CUI [1,2]
C0002712
UMLS CUI [2,1]
C0440048
UMLS CUI [2,2]
C0332288
UMLS CUI [2,3]
C0002712
Oil red O
Descripción

Oil red O

Tipo de datos

boolean

Alias
UMLS CUI [1]
C1294000
Congo red
Descripción

Congo red

Tipo de datos

boolean

Alias
UMLS CUI [1]
C0009742
Hall's stain
Descripción

Hall's stain

Tipo de datos

boolean

Alias
UMLS CUI [1]
C1720394
Gridley's stain
Descripción

Gridley's stain

Tipo de datos

boolean

Alias
UMLS CUI [1]
C1293978
Rhodanine (copper)
Descripción

Rhodanine

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C0035486
UMLS CUI [1,2]
C0009968
UMLS CUI [1,3]
C0487602
Rubeanic acid (copper)
Descripción

Rubeanic acid

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C0073680
UMLS CUI [1,2]
C0009968
UMLS CUI [1,3]
C0487602
Orcein, aldehyde fuchsin or Victoria blue
Descripción

Orcein, aldehyde fuchsin or Victoria blue

Tipo de datos

boolean

Alias
UMLS CUI [1]
C1294001
UMLS CUI [2]
C0491984
UMLS CUI [3,1]
C0078232
UMLS CUI [3,2]
C0487602
Electron microscopy
Descripción

Electron microscopy

Tipo de datos

boolean

Alias
UMLS CUI [1]
C0026019
Hepatitis A immunostains positive
Descripción

Hepatitis A immunostains positive

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C0560226
UMLS CUI [1,2]
C3687908
Hepatitis B core antigen or hepatitis B surface antibody immunostains positive
Descripción

Hepatitis B core antigen or hepatitis B surface antibody immunostains positive

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C0019166
UMLS CUI [1,2]
C3687908
UMLS CUI [2,1]
C0369334
UMLS CUI [2,2]
C3687908
Hepatitis D immunostains
Descripción

Hepatitis D immunostains

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C0011226
UMLS CUI [1,2]
C3687908
Other immunostains
Descripción

Other immunostains

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C3687908
UMLS CUI [1,2]
C0205394
Other
Descripción

Other Histologic Staining or Additional Studies Obtained

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C0487602
UMLS CUI [1,2]
C0205394
Other, specify:
Descripción

Other Histologic Staining or Additional Studies Obtained specification

Tipo de datos

text

Alias
UMLS CUI [1,1]
C0487602
UMLS CUI [1,2]
C0205394
UMLS CUI [1,3]
C2348235

Similar models

Liver biopsy

  1. StudyEvent: ODM
    1. Liver biopsy
Name
Tipo
Description | Question | Decode (Coded Value)
Tipo de datos
Alias
Item Group
Administrative Data
C1320722 (UMLS CUI-1)
Subject Identifier
Item
Subject Identifier
integer
C2348585 (UMLS CUI [1])
Date of Visit/Assessment
Item
Date of visit/assessment
date
C1320303 (UMLS CUI [1])
Item Group
Date of liver biopsy
C0193388 (UMLS CUI-1)
C0011008 (UMLS CUI-2)
Date of liver biopsy
Item
1. Date of liver biopsy
date
C0193388 (UMLS CUI [1,1])
C0011008 (UMLS CUI [1,2])
Item Group
Biopsy size
C1299482 (UMLS CUI-1)
C0193388 (UMLS CUI-2)
Liver Biopsy size
Item
2. Approximate size of liver biopsy
integer
C1299482 (UMLS CUI [1,1])
C0193388 (UMLS CUI [1,2])
Item Group
Final Diagnosis
C1546485 (UMLS CUI-1)
C0193388 (UMLS CUI-2)
Item
3. Final Diagnosis
text
C1546485 (UMLS CUI [1,1])
C0193388 (UMLS CUI [1,2])
Code List
3. Final Diagnosis
CL Item
Normal (Normal)
CL Item
Check all that apply (Check all that apply)
Acute hepatitis
Item
Acute hepatitis
boolean
C0267797 (UMLS CUI [1])
Chronic hepatitis
Item
Chronic hepatitis
boolean
C0019189 (UMLS CUI [1])
Cholestatic hepatitis
Item
Cholestatic hepatitis
boolean
C0149904 (UMLS CUI [1])
Drug-induced cholestasis
Item
Drug-induced cholestasis
boolean
C2062350 (UMLS CUI [1])
Acute viral hepatitis
Item
Acute viral hepatitis
boolean
C0276622 (UMLS CUI [1])
Chronic viral hepatitis
Item
Chronic viral hepatitis
boolean
C0276623 (UMLS CUI [1])
Drug-induced hepatitis
Item
Drug-induced hepatitis
boolean
C1262760 (UMLS CUI [1])
Autoimmune hepatitis
Item
Autoimmune hepatitis
boolean
C0241910 (UMLS CUI [1])
Liver Bridging necrosis
Item
Bridging necrosis
boolean
C0333511 (UMLS CUI [1,1])
C0023884 (UMLS CUI [1,2])
Submassive hepatic necrosis
Item
Submassive hepatic necrosis
boolean
C0151798 (UMLS CUI [1])
Massive hepatic necrosis
Item
Massive hepatic necrosis
boolean
C0001364 (UMLS CUI [1])
Steatosis - microvesicular
Item
Steatosis - microvesicular
boolean
C1850415 (UMLS CUI [1])
Steatosis - macrovesicular
Item
Steatosis - macrovesicular
boolean
C1837256 (UMLS CUI [1])
Steatosis - mixed
Item
Steatosis - mixed
boolean
C0015695 (UMLS CUI [1,1])
C0205430 (UMLS CUI [1,2])
Non-alcoholic steatohepatitis
Item
Non-alcoholic steatohepatitis
boolean
C3241937 (UMLS CUI [1])
Alcoholic hepatitis
Item
Alcoholic hepatitis
boolean
C0019187 (UMLS CUI [1])
Hepatic granulomas
Item
Hepatic granulomas
boolean
C0745754 (UMLS CUI [1])
Liver Sarcoidosis
Item
Sarcoidosis
boolean
C0744822 (UMLS CUI [1])
Liver Fibrosis
Item
Fibrosis
boolean
C0239946 (UMLS CUI [1])
Cirrhosis
Item
Cirrhosis
boolean
C0023890 (UMLS CUI [1])
Primary biliary cirrhosis
Item
Primary biliary cirrhosis
boolean
C0008312 (UMLS CUI [1])
Primary sclerosing cholangitis
Item
Primary sclerosing cholangitis
boolean
C0008311 (UMLS CUI [1])
Autoimmune overlap syndrome
Item
Autoimmune overlap syndrome
boolean
C2702837 (UMLS CUI [1])
Hemochromatosis
Item
Hemochromatosis
boolean
C0018995 (UMLS CUI [1])
Alpha-1-antitrypsin deficiency
Item
Alpha-1-antitrypsin deficiency
boolean
C0221757 (UMLS CUI [1])
Wilson's disease
Item
Wilson's disease
boolean
C0019202 (UMLS CUI [1])
Liver: Veno-occlusive disease
Item
Veno-occlusive disease
boolean
C0019156 (UMLS CUI [1])
Budd-Chiari syndrome
Item
Budd-Chiari syndrome
boolean
C0856761 (UMLS CUI [1])
Liver Neoplasia
Item
Neoplasia
boolean
C1882062 (UMLS CUI [1,1])
C0023884 (UMLS CUI [1,2])
Other Final Diagnosis
Item
Other
boolean
C1546485 (UMLS CUI [1,1])
C0205394 (UMLS CUI [1,2])
Other Final Diagnosis specification
Item
Other, specify:
text
C1546485 (UMLS CUI [1,1])
C0205394 (UMLS CUI [1,2])
C2348235 (UMLS CUI [1,3])
Item Group
Liver Architecture
C0023884 (UMLS CUI-1)
C0935919 (UMLS CUI-2)
Item
4. Liver Architecture
text
C0935919 (UMLS CUI [1,1])
C0023884 (UMLS CUI [1,2])
Code List
4. Liver Architecture
CL Item
Normal (Normal1)
CL Item
Check all that apply (Check all that apply)
Liver: Bridging fibrosis
Item
Bridging fibrosis
boolean
C0334160 (UMLS CUI [1,1])
C0023884 (UMLS CUI [1,2])
Diffuse fibrosis
Item
Diffuse fibrosis
boolean
C1265984 (UMLS CUI [1,1])
C0023884 (UMLS CUI [1,2])
Liver: Nodular regenerative hyperplasia
Item
Nodular regenerative hyperplasia
boolean
C0020510 (UMLS CUI [1,1])
C0023884 (UMLS CUI [1,2])
Congenital hepatic fibrosis
Item
Congenital hepatic fibrosis
boolean
C0009714 (UMLS CUI [1])
Cirrhosis
Item
Cirrhosis
boolean
C0023890 (UMLS CUI [1])
Centrilobular congestion
Item
Centrilobular congestion
boolean
C0267821 (UMLS CUI [1,1])
C0442080 (UMLS CUI [1,2])
Liver Endophlebitis
Item
Endophlebitis
boolean
C0014234 (UMLS CUI [1,1])
C0023884 (UMLS CUI [1,2])
Liver Veno-occlusive disease
Item
Veno-occlusive disease
boolean
C0019156 (UMLS CUI [1])
Canalicular cholestasis
Item
Canalicular cholestasis
boolean
C3150342 (UMLS CUI [1])
Liver Apoptosis
Item
Apoptosis
boolean
C0162638 (UMLS CUI [1,1])
C0023884 (UMLS CUI [1,2])
Focal (or spotty or mild) hepatocellular necrosis
Item
Focal (or spotty or mild) hepatocellular necrosis
boolean
C0267800 (UMLS CUI [1])
Interface hepatitis
Item
Interface hepatitis (periportal hepatitis or piecemeal necrosis)
boolean
C0333515 (UMLS CUI [1,1])
C0023884 (UMLS CUI [1,2])
Liver: Ischaemic necrosis
Item
Ischaemic necrosis
boolean
C3887513 (UMLS CUI [1,1])
C0023884 (UMLS CUI [1,2])
Centrolobular necrosis
Item
Centrolobular (Zone 3) necrosis
boolean
C3672032 (UMLS CUI [1])
Focal coagulative necrosis
Item
Focal coagulative necrosis
boolean
C1522058 (UMLS CUI [1,1])
C0205234 (UMLS CUI [1,2])
Centrolobular coagulative necrosis
Item
Centrolobular (Zone 3) coagulative necrosis
boolean
C1522058 (UMLS CUI [1,1])
C0682619 (UMLS CUI [1,2])
Bridging hepatocellular necrosis
Item
Bridging hepatocellular necrosis
boolean
C1855038 (UMLS CUI [1,1])
C0333511 (UMLS CUI [1,2])
Massive or panlobular hepatocellular necrosis
Item
Massive or panlobular hepatocellular necrosis
boolean
C1855038 (UMLS CUI [1,1])
C0442131 (UMLS CUI [1,2])
C0001364 (UMLS CUI [2])
Liver Dysplasia
Item
Dysplasia
boolean
C0334044 (UMLS CUI [1,1])
C0023884 (UMLS CUI [1,2])
Liver Neoplasia
Item
Neoplasia
boolean
C1882062 (UMLS CUI [1,1])
C0023884 (UMLS CUI [1,2])
Other Liver Architecture
Item
Other
boolean
C0023884 (UMLS CUI [1,1])
C0935919 (UMLS CUI [1,2])
C0205394 (UMLS CUI [1,3])
Other Liver Architecture specification
Item
Other, specify:
text
C0935919 (UMLS CUI [1,1])
C0023884 (UMLS CUI [1,2])
C0205394 (UMLS CUI [1,3])
C2348235 (UMLS CUI [1,4])
Item Group
Description of Liver Cells or Hepatocytes
C0227525 (UMLS CUI-1)
C0678257 (UMLS CUI-2)
Item
5. Description of Liver Cells or Hepatocytes
text
C0227525 (UMLS CUI [1,1])
C0678257 (UMLS CUI [1,2])
Code List
5. Description of Liver Cells or Hepatocytes
CL Item
Normal (Normal)
CL Item
Check all that apply (Check all that apply)
Ballooning Liver Cells or Hepatocytes
Item
Ballooning
boolean
C0333445 (UMLS CUI [1,1])
C0227525 (UMLS CUI [1,2])
Acidophilic Liver Cells or Hepatocytes
Item
Acidophilic
boolean
C0227525 (UMLS CUI [1,1])
C0333931 (UMLS CUI [1,2])
Pseudoxanthomatous Liver Cells or Hepatocytes
Item
Pseudoxanthomatous
boolean
C0227525 (UMLS CUI [1,1])
C3277905 (UMLS CUI [1,2])
Multinucleated giant hepatocytes
Item
Multinucleated giant hepatocytes
boolean
C3550474 (UMLS CUI [1,1])
C1850414 (UMLS CUI [1,2])
Other Liver Cells or Hepatocytes
Item
Other
boolean
C0227525 (UMLS CUI [1,1])
C0678257 (UMLS CUI [1,2])
C0205394 (UMLS CUI [1,3])
Other Liver Cells or Hepatocytes specification
Item
Other, specify:
text
C0227525 (UMLS CUI [1,1])
C0678257 (UMLS CUI [1,2])
C0205394 (UMLS CUI [1,3])
C2348235 (UMLS CUI [1,4])
Item Group
Liver Cell or Hepatocyte Inclusions or Vacuoles
C0227525 (UMLS CUI-1)
C1512693 (UMLS CUI-2)
C0042219 (UMLS CUI-3)
Item
8. Liver Cell or Hepatocyte Inclusions or Vacuoles
text
C0227525 (UMLS CUI [1,1])
C0042219 (UMLS CUI [1,2])
C0227525 (UMLS CUI [2,1])
C1512693 (UMLS CUI [2,2])
Code List
8. Liver Cell or Hepatocyte Inclusions or Vacuoles
CL Item
No inclusions (No inclusions)
CL Item
Check all that apply (Check all that apply)
Macrovesicular steatosis
Item
Macrovesicular steatosis
boolean
C1837256 (UMLS CUI [1])
Microvesicular steatosis
Item
Microvesicular steatosis
boolean
C1850415 (UMLS CUI [1])
Bile accumulation
Item
Bile accumulation
boolean
C3686784 (UMLS CUI [1])
Diastase-resistant, PAS-positive cytoplasmic inclusions
Item
Diastase-resistant, PAS-positive cytoplasmic inclusions
boolean
C1856311 (UMLS CUI [1])
Alpha-1-antitrypsin inclusions
Item
Alpha-1-antitrypsin inclusions
boolean
C0002191 (UMLS CUI [1,1])
C1512693 (UMLS CUI [1,2])
C0227525 (UMLS CUI [1,3])
Megamitochondria
Item
Megamitochondria
boolean
C0544931 (UMLS CUI [1,1])
C0227525 (UMLS CUI [1,2])
Mallory bodies
Item
Mallory bodies
boolean
C0333744 (UMLS CUI [1])
Ground Glass inclusions
Item
"Ground Glass" inclusions
boolean
C0598786 (UMLS CUI [1])
Hepatocyte Lipofuscin pigment
Item
Lipofuscin pigment
boolean
C0023789 (UMLS CUI [1,1])
C0227525 (UMLS CUI [1,2])
Hemosiderin granules
Item
Hemosiderin granules
boolean
C0019113 (UMLS CUI [1,1])
C0227525 (UMLS CUI [1,2])
Orcein-positive cytoplasmin granules
Item
Orcein-positive cytoplasmin granules
boolean
C0069596 (UMLS CUI [1,1])
C0227525 (UMLS CUI [1,2])
Protoporphyrin crystals
Item
Protoporphyrin crystals (birefringent under polarised light)
boolean
C0033733 (UMLS CUI [1,1])
C0227525 (UMLS CUI [1,2])
Uroporphyrin crystals
Item
Uroporphyrin crystals (red fluorescence under ultraviolet light)
boolean
C0042093 (UMLS CUI [1,1])
C0227525 (UMLS CUI [1,2])
Other Liver Cell or Hepatocyte Inclusions or Vacuoles
Item
Other
boolean
C0227525 (UMLS CUI [1,1])
C0042219 (UMLS CUI [1,2])
C0205394 (UMLS CUI [1,3])
C0227525 (UMLS CUI [2,1])
C1512693 (UMLS CUI [2,2])
C0205394 (UMLS CUI [2,3])
Other Liver Cell or Hepatocyte Inclusions or Vacuoles specification
Item
Other, specify:
text
C0227525 (UMLS CUI [1,1])
C0042219 (UMLS CUI [1,2])
C0205394 (UMLS CUI [1,3])
C0227525 (UMLS CUI [2,1])
C1512693 (UMLS CUI [2,2])
C0205394 (UMLS CUI [2,3])
C1521902 (UMLS CUI [3])
Item Group
Hepatocyte or Liver Cell Nuclear Abnormalities
C0227525 (UMLS CUI-1)
C1849376 (UMLS CUI-2)
Item
7. Hepatocyte or Liver Cell Nuclear Abnormalities
text
C0227525 (UMLS CUI [1,1])
C1849376 (UMLS CUI [1,2])
Code List
7. Hepatocyte or Liver Cell Nuclear Abnormalities
CL Item
None (None)
CL Item
Check all that apply (Check all that apply)
Hepatocellular mitosis
Item
Hepatocellular mitosis
boolean
C2697585 (UMLS CUI [1,1])
C0026255 (UMLS CUI [1,2])
Binucleated or multinucleated hepatocytes
Item
Binucleated or multinucleated hepatocytes
boolean
C0227525 (UMLS CUI [1,1])
C0333909 (UMLS CUI [1,2])
C4054455 (UMLS CUI [2])
CMV inclusion bodies
Item
CMV inclusion bodies
boolean
C0582172 (UMLS CUI [1,1])
C1366904 (UMLS CUI [1,2])
C0227525 (UMLS CUI [1,3])
HSV inclusions
Item
HSV inclusions
boolean
C0319232 (UMLS CUI [1,1])
C1366904 (UMLS CUI [1,2])
C0227525 (UMLS CUI [1,3])
Varicella inclusions
Item
Varicella inclusions
boolean
C0740380 (UMLS CUI [1,1])
C1366904 (UMLS CUI [1,2])
C0227525 (UMLS CUI [1,3])
Other Hepatocyte or Liver Cell Nuclear Abnormalities
Item
Other
boolean
C0227525 (UMLS CUI [1,1])
C1849376 (UMLS CUI [1,2])
C0205394 (UMLS CUI [1,3])
Other Hepatocyte or Liver Cell Nuclear Abnormalities specification
Item
Other, specify:
text
C0227525 (UMLS CUI [1,1])
C1849376 (UMLS CUI [1,2])
C0205394 (UMLS CUI [1,3])
C1521902 (UMLS CUI [1,4])
Item Group
Liver or Lobular Infiltrates
C0205417 (UMLS CUI-1)
C1400896 (UMLS CUI-2)
C1400896 (UMLS CUI-4)
Item
8. Liver or Lobular Infiltrates
text
C0205417 (UMLS CUI [1,1])
C1400896 (UMLS CUI [1,2])
C1400896 (UMLS CUI [2])
Code List
8. Liver or Lobular Infiltrates
CL Item
None (None)
CL Item
Check all that apply (Check all that apply)
Liver or Lobular Infiltrates Eosinophils
Item
Eosinophils
boolean
C0205417 (UMLS CUI [1,1])
C1400896 (UMLS CUI [1,2])
C0014467 (UMLS CUI [1,3])
C1400896 (UMLS CUI [2,1])
C0014467 (UMLS CUI [2,2])
Liver or Lobular Infiltrates Lymphocytes
Item
Lymphocytes
boolean
C0205417 (UMLS CUI [1,1])
C1400896 (UMLS CUI [1,2])
C0024264 (UMLS CUI [1,3])
C1400896 (UMLS CUI [2,1])
C0024264 (UMLS CUI [2,2])
Liver or Lobular Infiltrates Plasma cells
Item
Plasma cells
boolean
C0205417 (UMLS CUI [1,1])
C1400896 (UMLS CUI [1,2])
C0032112 (UMLS CUI [1,3])
C1400896 (UMLS CUI [2,1])
C0032112 (UMLS CUI [2,2])
Liver or Lobular Infiltrates Neutrophils
Item
Neutrophils
boolean
C0205417 (UMLS CUI [1,1])
C1400896 (UMLS CUI [1,2])
C0027950 (UMLS CUI [1,3])
C1400896 (UMLS CUI [2,1])
C0027950 (UMLS CUI [2,2])
Liver or Lobular Infiltrates Macrophages and proliferating Kupffer cells
Item
Macrophages and proliferating Kupffer cells
boolean
C0205417 (UMLS CUI [1,1])
C1400896 (UMLS CUI [1,2])
C0022801 (UMLS CUI [1,3])
C1400896 (UMLS CUI [2,1])
C0022801 (UMLS CUI [2,2])
C1168262 (UMLS CUI [3])
Liver or Lobular Infiltrates Granulomas
Item
Granulomas
boolean
C0745754 (UMLS CUI [1,1])
C0205417 (UMLS CUI [1,2])
C0745754 (UMLS CUI [2])
Other Liver or Lobular Infiltrates
Item
Other
boolean
C0205417 (UMLS CUI [1,1])
C1400896 (UMLS CUI [1,2])
C0205394 (UMLS CUI [1,3])
C1400896 (UMLS CUI [2,1])
C0205394 (UMLS CUI [2,2])
Other Liver or Lobular Infiltrates specification
Item
Other, specify:
text
C0205417 (UMLS CUI [1,1])
C1400896 (UMLS CUI [1,2])
C0205394 (UMLS CUI [1,3])
C1400896 (UMLS CUI [2,1])
C0205394 (UMLS CUI [2,2])
C1521902 (UMLS CUI [3])
Item Group
Portal Tract Inflammation
C3854488 (UMLS CUI-1)
Item
9. Portal Tract Inflammation
text
C3854488 (UMLS CUI [1])
Code List
9. Portal Tract Inflammation
CL Item
None (None)
CL Item
Check all that apply (Check all that apply)
Portal Tract Inflammation Eosinophils
Item
Eosinophils
boolean
C0014467 (UMLS CUI [1,1])
C3854488 (UMLS CUI [1,2])
Portal Tract Inflammation Lymphoid aggregates and/or follicles
Item
Lymphoid aggregates and/or follicles
boolean
C3854488 (UMLS CUI [1,1])
C0229653 (UMLS CUI [1,2])
Portal Tract Inflammation Plasma cells
Item
Plasma cells
boolean
C3854488 (UMLS CUI [1,1])
C0032112 (UMLS CUI [1,2])
Portal Tract Inflammation Neutrophils
Item
Neutrophils
boolean
C3854488 (UMLS CUI [1,1])
C0027950 (UMLS CUI [1,2])
Portal Tract Inflammation Histocytes and macrophages
Item
Histocytes and macrophages
boolean
C3854488 (UMLS CUI [1,1])
C0024432 (UMLS CUI [1,2])
C3854488 (UMLS CUI [2,1])
C0019612 (UMLS CUI [2,2])
Other Portal Tract Inflammation
Item
Other
boolean
C3854488 (UMLS CUI [1,1])
C0205394 (UMLS CUI [1,2])
Other Portal Tract Inflammation specification
Item
Other, specify:
text
C3854488 (UMLS CUI [1,1])
C3845569 (UMLS CUI [1,2])
Item Group
Bile Ducts
C0005400 (UMLS CUI-1)
Item
10. Bile Ducts
text
C0005400 (UMLS CUI [1])
Code List
10. Bile Ducts
CL Item
Normal (Normal)
CL Item
Check all that apply (Check all that apply)
Proliferation of bile ducts
Item
Proliferation of bile ducts (bile ductular reaction)
boolean
C0005400 (UMLS CUI [1,1])
C0334094 (UMLS CUI [1,2])
Dilation, degeneration or disruption of portal bile ducts
Item
Dilation, degeneration or disruption of portal bile ducts
boolean
C0005400 (UMLS CUI [1,1])
C0011164 (UMLS CUI [1,2])
C1849767 (UMLS CUI [2])
C0005400 (UMLS CUI [3,1])
C0332453 (UMLS CUI [3,2])
Paucity of bile ducts
Item
Paucity of bile ducts
boolean
C4273160 (UMLS CUI [1])
Periductal fibrosis
Item
Periductal fibrosis
boolean
C0016059 (UMLS CUI [1,1])
C0005400 (UMLS CUI [1,2])
Bile ducts Other
Item
Other
boolean
C0205394 (UMLS CUI [1,1])
C0005400 (UMLS CUI [1,2])
Bile ducts Other specification
Item
Other, specify
text
C0205394 (UMLS CUI [1,1])
C0005400 (UMLS CUI [1,2])
C2348235 (UMLS CUI [1,3])
Item Group
Portal Veins
C0032718 (UMLS CUI-1)
Item
11. Portal Veins
text
C0032718 (UMLS CUI [1])
Code List
11. Portal Veins
CL Item
Normal (Normal)
CL Item
Check all that apply (Check all that apply)
Pyelophlebitis
Item
Pyelophlebitis
boolean
C1405883 (UMLS CUI [1,1])
C0032718 (UMLS CUI [1,2])
Thrombosis, sclerosis or occlusion of portal vein
Item
Thrombosis, sclerosis or occlusion of portal vein
boolean
C0155773 (UMLS CUI [1])
C0400960 (UMLS CUI [2])
C0265029 (UMLS CUI [3])
Neoplastic invasion of portal vein
Item
Neoplastic invasion of portal vein
boolean
C1709160 (UMLS CUI [1,1])
C1510886 (UMLS CUI [1,2])
C0032718 (UMLS CUI [1,3])
Granulomatous compression of portal vein
Item
Granulomatous compression of portal vein
boolean
C0032718 (UMLS CUI [1,1])
C0439667 (UMLS CUI [1,2])
C0728907 (UMLS CUI [1,3])
Portal veins Other
Item
Other
boolean
C0032718 (UMLS CUI [1,1])
C0205394 (UMLS CUI [1,2])
Portal veins Other specification
Item
Other, specify:
text
C0032718 (UMLS CUI [1,1])
C0205394 (UMLS CUI [1,2])
C2348235 (UMLS CUI [1,3])
Item Group
Liver Infections
C1112211 (UMLS CUI-1)
Item
12. Liver Infections
text
C1112211 (UMLS CUI [1])
Code List
12. Liver Infections
CL Item
Normal (Normal)
CL Item
Check all that apply (Check all that apply)
Liver: Leishmaniasis donovani
Item
Leishmaniasis donovani
boolean
C0023273 (UMLS CUI [1,1])
C1112211 (UMLS CUI [1,2])
Liver: Plasmodium falciparum
Item
Plasmodium falciparum
boolean
C0032150 (UMLS CUI [1,1])
C1112211 (UMLS CUI [1,2])
Liver: Toxoplasmosis
Item
Toxoplasmosis
boolean
C0040558 (UMLS CUI [1,1])
C1112211 (UMLS CUI [1,2])
Liver: Cryptococcus neoformans
Item
Cryptococcus neoformans
boolean
C0010416 (UMLS CUI [1,1])
C1112211 (UMLS CUI [1,2])
Liver: Histoplasma capsulatum
Item
Histoplasma capsulatum
boolean
C0319941 (UMLS CUI [1,1])
C1112211 (UMLS CUI [1,2])
Liver: Mycobacterium tuberculois
Item
Mycobacterium tuberculois
boolean
C0026926 (UMLS CUI [1,1])
C1112211 (UMLS CUI [1,2])
Other mycobacterial species
Item
Other mycobacterial species
boolean
C0205394 (UMLS CUI [1,1])
C0026918 (UMLS CUI [1,2])
C1112211 (UMLS CUI [1,3])
Other Liver Infections
Item
Other
boolean
C1112211 (UMLS CUI [1,1])
C0205394 (UMLS CUI [1,2])
Other Liver Infections specification
Item
Other, specify:
text
C1112211 (UMLS CUI [1,1])
C0205394 (UMLS CUI [1,2])
C2348235 (UMLS CUI [1,3])
Item Group
Parasites or Ova
C0030498 (UMLS CUI-1)
C1267673 (UMLS CUI-2)
C0023884 (UMLS CUI-3)
Item
13. Parasites or Ova
text
C0030498 (UMLS CUI [1,1])
C0023884 (UMLS CUI [1,2])
C0555117 (UMLS CUI [2,1])
C0023884 (UMLS CUI [2,2])
Code List
13. Parasites or Ova
CL Item
None (None)
CL Item
Check all that apply (Check all that apply)
Schistosome and/or ova
Item
Schistosome and/or ova
boolean
C4303012 (UMLS CUI [1,1])
C0023884 (UMLS CUI [1,2])
C0036315 (UMLS CUI [2,1])
C0023884 (UMLS CUI [2,2])
Ascaris and/or ova
Item
Ascaris and/or ova
boolean
C3698183 (UMLS CUI [1,1])
C0023884 (UMLS CUI [1,2])
C0003954 (UMLS CUI [2,1])
C0023884 (UMLS CUI [2,2])
Toxocara and/or ova
Item
Toxocara and/or ova
boolean
C0040550 (UMLS CUI [1,1])
C1267673 (UMLS CUI [1,2])
C0023884 (UMLS CUI [1,3])
C0040550 (UMLS CUI [2,1])
C0023884 (UMLS CUI [2,2])
Echinococcus cysts
Item
Echinococcus cysts
boolean
C0013502 (UMLS CUI [1])
Hepatic capillariasis worms and/or ova
Item
Hepatic capillariasis worms and/or ova
boolean
C0006896 (UMLS CUI [1,1])
C1267673 (UMLS CUI [1,2])
C0023884 (UMLS CUI [1,3])
C0277202 (UMLS CUI [2,1])
C0023884 (UMLS CUI [2,2])
Other Parasites or Ova
Item
Other
boolean
C0030498 (UMLS CUI [1,1])
C0205394 (UMLS CUI [1,2])
C0023884 (UMLS CUI [1,3])
C1267673 (UMLS CUI [2,1])
C0205394 (UMLS CUI [2,2])
C0023884 (UMLS CUI [2,3])
Other Parasites or Ova specification
Item
Other, specify:
text
C0030498 (UMLS CUI [1,1])
C0205394 (UMLS CUI [1,2])
C0023884 (UMLS CUI [1,3])
C1267673 (UMLS CUI [2,1])
C0205394 (UMLS CUI [2,2])
C0023884 (UMLS CUI [2,3])
C2348235 (UMLS CUI [3])
Item Group
14. Histologic Staining or Additional Studies Obtained
C0487602 (UMLS CUI-1)
C0430022 (UMLS CUI-2)
C0023884 (UMLS CUI-3)
Haematoxylin and eosin
Item
Haematoxylin and eosin (or H & E)
boolean
C0523207 (UMLS CUI [1])
Masson
Item
Masson
boolean
C1294297 (UMLS CUI [1])
Toluidine blue or Giemsa
Item
Toluidine blue or Giemsa
boolean
C0523203 (UMLS CUI [1])
C0017542 (UMLS CUI [2])
Prussian blue
Item
Prussian blue
boolean
C1294004 (UMLS CUI [1])
Periodic Acidic Schiff with or without diastase
Item
Periodic Acidic Schiff (PAS), with or without diastase
boolean
C0440048 (UMLS CUI [1,1])
C0002712 (UMLS CUI [1,2])
C0440048 (UMLS CUI [2,1])
C0332288 (UMLS CUI [2,2])
C0002712 (UMLS CUI [2,3])
Oil red O
Item
Oil red O
boolean
C1294000 (UMLS CUI [1])
Congo red
Item
Congo red
boolean
C0009742 (UMLS CUI [1])
Hall's stain
Item
Hall's stain
boolean
C1720394 (UMLS CUI [1])
Gridley's stain
Item
Gridley's stain
boolean
C1293978 (UMLS CUI [1])
Rhodanine
Item
Rhodanine (copper)
boolean
C0035486 (UMLS CUI [1,1])
C0009968 (UMLS CUI [1,2])
C0487602 (UMLS CUI [1,3])
Rubeanic acid
Item
Rubeanic acid (copper)
boolean
C0073680 (UMLS CUI [1,1])
C0009968 (UMLS CUI [1,2])
C0487602 (UMLS CUI [1,3])
Orcein, aldehyde fuchsin or Victoria blue
Item
Orcein, aldehyde fuchsin or Victoria blue
boolean
C1294001 (UMLS CUI [1])
C0491984 (UMLS CUI [2])
C0078232 (UMLS CUI [3,1])
C0487602 (UMLS CUI [3,2])
Electron microscopy
Item
Electron microscopy
boolean
C0026019 (UMLS CUI [1])
Hepatitis A immunostains positive
Item
Hepatitis A immunostains positive
boolean
C0560226 (UMLS CUI [1,1])
C3687908 (UMLS CUI [1,2])
Hepatitis B core antigen or hepatitis B surface antibody immunostains positive
Item
Hepatitis B core antigen or hepatitis B surface antibody immunostains positive
boolean
C0019166 (UMLS CUI [1,1])
C3687908 (UMLS CUI [1,2])
C0369334 (UMLS CUI [2,1])
C3687908 (UMLS CUI [2,2])
Hepatitis D immunostains
Item
Hepatitis D immunostains
boolean
C0011226 (UMLS CUI [1,1])
C3687908 (UMLS CUI [1,2])
Other immunostains
Item
Other immunostains
boolean
C3687908 (UMLS CUI [1,1])
C0205394 (UMLS CUI [1,2])
Other Histologic Staining or Additional Studies Obtained
Item
Other
boolean
C0487602 (UMLS CUI [1,1])
C0205394 (UMLS CUI [1,2])
Other Histologic Staining or Additional Studies Obtained specification
Item
Other, specify:
text
C0487602 (UMLS CUI [1,1])
C0205394 (UMLS CUI [1,2])
C2348235 (UMLS CUI [1,3])

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