ID

40877

Descripción

Sorafenib Plus Vitamin K1 Versus Sorafenib in Advanced Hepatocellular Carcinoma; ODM derived from: https://clinicaltrials.gov/show/NCT02259647

Link

https://clinicaltrials.gov/show/NCT02259647

Palabras clave

  1. 29/5/20 29/5/20 -
  2. 27/9/21 27/9/21 -
Titular de derechos de autor

See clinicaltrials.gov

Subido en

29 de mayo de 2020

DOI

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Licencia

Creative Commons BY 4.0

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Eligibility Hepatocellular Carcinoma NCT02259647

Eligibility Hepatocellular Carcinoma NCT02259647

Inclusion Criteria
Descripción

Inclusion Criteria

Alias
UMLS CUI
C1512693
age 18 to 70 years
Descripción

Age

Tipo de datos

boolean

Alias
UMLS CUI [1]
C0001779
child a and b cirrhosis with hepatocellular carcinoma
Descripción

Liver Cirrhosis Child-Pugh Classification | Liver carcinoma

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C0023890
UMLS CUI [1,2]
C2347612
UMLS CUI [2]
C2239176
biochemical, radiological, histological evidence of advanced hepatocellular carcinoma diagnosed as stage c and stage d with serum bilirubin <5 mg/dl according to bclc staging system
Descripción

Advanced Hepatocellular Carcinoma BCLC Stage | Serum total bilirubin measurement

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C1706732
UMLS CUI [1,2]
C3899974
UMLS CUI [2]
C1278039
hcc with portal vein thrombosis
Descripción

Liver carcinoma | Portal vein thrombosis

Tipo de datos

boolean

Alias
UMLS CUI [1]
C2239176
UMLS CUI [2]
C0155773
unresectable cancer, as assessed carefully by individual experts
Descripción

Unresectable Malignant Neoplasm

Tipo de datos

boolean

Alias
UMLS CUI [1]
C1336869
no recent active treatment like surgery, radiofrequency ablation, trans arterial chemo embolization, radiotherapy, chemotherapy (within the past 6 months)
Descripción

Therapeutic procedure Absent | Operative Surgical Procedures Absent | Radiofrequency ablation Absent | Transarterial Chemoembolization Absent | Therapeutic radiology procedure Absent | Chemotherapy Absent

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C0087111
UMLS CUI [1,2]
C0332197
UMLS CUI [2,1]
C0543467
UMLS CUI [2,2]
C0332197
UMLS CUI [3,1]
C0850292
UMLS CUI [3,2]
C0332197
UMLS CUI [4,1]
C3539919
UMLS CUI [4,2]
C0332197
UMLS CUI [5,1]
C1522449
UMLS CUI [5,2]
C0332197
UMLS CUI [6,1]
C0392920
UMLS CUI [6,2]
C0332197
Exclusion Criteria
Descripción

Exclusion Criteria

Alias
UMLS CUI
C0680251
patients with end-stage hepatocellular carcinoma (stage d, bclc)with poor performance status
Descripción

End-stage Liver carcinoma BCLC Stage | Poor performance status

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C0205088
UMLS CUI [1,2]
C2239176
UMLS CUI [1,3]
C3899974
UMLS CUI [2]
C1831741
child c cirrhosis with hcc (hepatocellular carcinoma)
Descripción

Liver Cirrhosis Child-Pugh Classification | Liver carcinoma

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C0023890
UMLS CUI [1,2]
C2347612
UMLS CUI [2]
C2239176
hcc with acute decompensated state of cld - gi bleed, increased jaundice, he, sbp (spontaneous bacterial peritonitis)
Descripción

Liver carcinoma | Chronic liver disease Decompensated | Gastrointestinal Hemorrhage | Icterus Increased | Hepatic Encephalopathy | Primary bacterial peritonitis

Tipo de datos

boolean

Alias
UMLS CUI [1]
C2239176
UMLS CUI [2,1]
C0341439
UMLS CUI [2,2]
C0205434
UMLS CUI [3]
C0017181
UMLS CUI [4,1]
C0022346
UMLS CUI [4,2]
C0205217
UMLS CUI [5]
C0019151
UMLS CUI [6]
C0275551
acute febrile illness
Descripción

Acute febrile illness

Tipo de datos

boolean

Alias
UMLS CUI [1]
C0743842
pregnancy or lactation
Descripción

Pregnancy | Breast Feeding

Tipo de datos

boolean

Alias
UMLS CUI [1]
C0032961
UMLS CUI [2]
C0006147

Similar models

Eligibility Hepatocellular Carcinoma NCT02259647

Name
Tipo
Description | Question | Decode (Coded Value)
Tipo de datos
Alias
Item Group
C1512693 (UMLS CUI)
Age
Item
age 18 to 70 years
boolean
C0001779 (UMLS CUI [1])
Liver Cirrhosis Child-Pugh Classification | Liver carcinoma
Item
child a and b cirrhosis with hepatocellular carcinoma
boolean
C0023890 (UMLS CUI [1,1])
C2347612 (UMLS CUI [1,2])
C2239176 (UMLS CUI [2])
Advanced Hepatocellular Carcinoma BCLC Stage | Serum total bilirubin measurement
Item
biochemical, radiological, histological evidence of advanced hepatocellular carcinoma diagnosed as stage c and stage d with serum bilirubin <5 mg/dl according to bclc staging system
boolean
C1706732 (UMLS CUI [1,1])
C3899974 (UMLS CUI [1,2])
C1278039 (UMLS CUI [2])
Liver carcinoma | Portal vein thrombosis
Item
hcc with portal vein thrombosis
boolean
C2239176 (UMLS CUI [1])
C0155773 (UMLS CUI [2])
Unresectable Malignant Neoplasm
Item
unresectable cancer, as assessed carefully by individual experts
boolean
C1336869 (UMLS CUI [1])
Therapeutic procedure Absent | Operative Surgical Procedures Absent | Radiofrequency ablation Absent | Transarterial Chemoembolization Absent | Therapeutic radiology procedure Absent | Chemotherapy Absent
Item
no recent active treatment like surgery, radiofrequency ablation, trans arterial chemo embolization, radiotherapy, chemotherapy (within the past 6 months)
boolean
C0087111 (UMLS CUI [1,1])
C0332197 (UMLS CUI [1,2])
C0543467 (UMLS CUI [2,1])
C0332197 (UMLS CUI [2,2])
C0850292 (UMLS CUI [3,1])
C0332197 (UMLS CUI [3,2])
C3539919 (UMLS CUI [4,1])
C0332197 (UMLS CUI [4,2])
C1522449 (UMLS CUI [5,1])
C0332197 (UMLS CUI [5,2])
C0392920 (UMLS CUI [6,1])
C0332197 (UMLS CUI [6,2])
Item Group
C0680251 (UMLS CUI)
End-stage Liver carcinoma BCLC Stage | Poor performance status
Item
patients with end-stage hepatocellular carcinoma (stage d, bclc)with poor performance status
boolean
C0205088 (UMLS CUI [1,1])
C2239176 (UMLS CUI [1,2])
C3899974 (UMLS CUI [1,3])
C1831741 (UMLS CUI [2])
Liver Cirrhosis Child-Pugh Classification | Liver carcinoma
Item
child c cirrhosis with hcc (hepatocellular carcinoma)
boolean
C0023890 (UMLS CUI [1,1])
C2347612 (UMLS CUI [1,2])
C2239176 (UMLS CUI [2])
Liver carcinoma | Chronic liver disease Decompensated | Gastrointestinal Hemorrhage | Icterus Increased | Hepatic Encephalopathy | Primary bacterial peritonitis
Item
hcc with acute decompensated state of cld - gi bleed, increased jaundice, he, sbp (spontaneous bacterial peritonitis)
boolean
C2239176 (UMLS CUI [1])
C0341439 (UMLS CUI [2,1])
C0205434 (UMLS CUI [2,2])
C0017181 (UMLS CUI [3])
C0022346 (UMLS CUI [4,1])
C0205217 (UMLS CUI [4,2])
C0019151 (UMLS CUI [5])
C0275551 (UMLS CUI [6])
Acute febrile illness
Item
acute febrile illness
boolean
C0743842 (UMLS CUI [1])
Pregnancy | Breast Feeding
Item
pregnancy or lactation
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])

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